NMN Vs NR For Longevity | Comparing NAD Booster Supplements
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- Опубликовано: 22 июл 2024
- NMN and NR are both NAD boosters...so which is better? In this video I will discuss the difference between NAD, NMN and NR, explaining how they work to increase lifespan and improve your overall health.
Free Gift: Guide for the 5 best supplements you can take: bit.ly/3CaLQCM
NAD stands Nicotinamide Adenine Dinucleotide and its important in your mitochondria, helping you convert food into energy. NAD is also important for maintaining your DNA to protect you from ageing and disease. Unfortunately, your levels of NAD naturally decline as you get older
Nicotinamide MonoNucleotide (NMN) is a precursor of NAD, & Nicotinamide Riboside (NR) is a precursor of NMN
You can take both NMN and NR orally and they both move into your bloodstream and get taken up into all of your cells.
NR is nice and small, so it gets taken up into your cells via a transporter, but NMN is medium sized and sometimes it can be taken up your cells...but sometimes it needs to be broken down into NR before it can move into your cells.
ANYWAY, once it’s in the cell, NR turns into NMN, NMN turns into NAD, and NAD works to make more energy and it also activates sirtuins, which slow down the ageing process.
Studies have shown that Yeast strains can live 30% longer when given NR, and mice have been shown to live 9% longer when given NR. Those mice also had more energy, less inflammation, and were generally healthier than the mice that didn’t receive NR
NMN vs NR Website
www.nmn.com/precursors/nmn-vs-nr
Sirtuins and NAD boosters
www.nature.com/articles/nrm.2...
2018 Review of NMN and NR
www.sciencedirect.com/science...
About NAD
www.aboutnad.com/nad-precursors
NR is orally bioavailable in humans and mice
pubmed.ncbi.nlm.nih.gov/27721...
NR increases lifespan in mice
pubmed.ncbi.nlm.nih.gov/27127...
NMN & NR research summary
blog.insidetracker.com/nr-nmn...
Similar studies with similar results have been seen with NMN. In terms of humans, there hasn’t been a lot of research yet. All we know is that taking 250-500mg of either NR or NMN orally will greatly increase your NAD levels.
The main difference between NMN and NR is the size. Because NR is smaller, it is cheaper to make in a laboratory so it’s probably cheaper to purchase.
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00:00 Intro
00:39 NAD Explained
01:13 NMN & NR Explained
01:32 How Do NMN & NR Work?
02:28 NMN & NR Current Research
02:57 NMN & NR Dosages
03:18 Which is Better? NMN or NR
Have you tried taking NMN or NAD supplements? Leave a comment and let us know what you think about NAD Boosters
TY for making these videos from a non biased scientific perspective. Very helpful.
This is super interesting. Thanks for making this video!
No worries Cassie Apple
Good video. Thanks.
Great content!
Exactly the information I was looking for with no bullshit attached, great video! Thanks :)
Excellent vid.
you are incredible 👏the best explanation 👏
well said. thanks
Thank you so much!
Top job 👍
Great explanation. Is there any proof that NMN can actually enter a cell without converting to NR? I think r. Sinclair had to back down on that claim. I take NR. It cleared up my psoriasis and I no longer feel stiff in the morning. Friends and family have benefitted too regarding peripheral neuropathy, restless leg syndrome, and lupus. I even give some to my 12 year old dog, who is doing great.
Well considering NMN is NR + a phosphate molecule I have no idea where you got the notion that NMN comes before NR in the pathway of producing NAD in a cell.
WOW I've been researching these supplements and finally I understand the difference. Thank you for explaining it so clearly. Do we need to take TMG or resversatrol or other supplements with either NR or NMN?? Which one is better for a 48 year old female to take that is on hormone replacement therapy estradiol patch, progesterone and testosterone gel.. also low dose of levothyroxine for hypothyroidism. Ty.
Thank you for your scientific review. I personally tried both. NR is much more effective for me for the same dosage probably because of its smaller molecular size.
Hey legend, I’m glad you agree that NR is more effective than NmN, although I’m sure both help to increase NaD levels and hence improve health span and life span. Thanks so much for watching and commenting, I appreciate you!
What's the dosage of NR compare to nmn 1000mg please
@@MultiKewalee its around 800mg
@@DUDIDUAN thank you 😊 🙏
This makes zero sense...lol. Both will increase NAD levels, and the molecule size has nothing to do with the efficacy.
Did dude really say "mouth hole". Lol
What do you think about resveratrol,?
What about liposomal nmn, does that change the game?
Hi 👋 there is study now that said there is link between b3 and heart disease can u tell me ur opinion?
Do you need to take gly nac with NR?
NR FTW!
If NR is converted to NMN which is converted to NAD, what is also needed for conversion? Obviously if we are short on that there will be no conversion. What else is needed to ensure we have what we need?
I have read that the efficiency of the process is influenced by our gut bacteria. I am not sure what to do regarding that - eat whole grains? eat yogurt with a variety of healthful bacteria? I do know that NR has helped me and friends and family. We also should try to regulate the glycol-protein CD38. That is done by eating various herbs and vegetables. CD38 inhibits NAD production and uses it up.
I've been taking NR for several weeks, for awhile i was full of energy like i was 16 again (I'm 31). Now that the effects have leveled off i still feel like I'm just overall in better shape.
But what brand is actually best
Can you make video about FISETIN …
Hey @Abdullah q8 interesting, I'll look into it an maybe I will :D Thanks for reaching out, I hope you check out some of my other videos
You didn't mention the missing phosphate molecule of NR. Once it is in the cell, won't it need the phosphate to convert to NMN? Would it deplete the phosphate in bones to get the phosphate?
I had the same question after watching Dr Sinclairs video , doesnt it depend upon the fact if your body is running low on Phosphate ??? A normal Human should be fine just with NR and may be keep alternating between NR and NMN. 2 Months of NR and 1 month of NMN.
NR is better for the body. NMN is way better for David Sinclair’s net worth.
Why NR is expensive than NMN?
Can I take both NR and NMN at the same time daily? If so what the daily dose for a 55 yr Male? Thank you 🙏
That wouldn't make sense to take both. Just choose 1.
@@Kelvintjju87Hi NR will convert to MNN and then it will convert to Nad .
NR>NMN so you don't watch the whole video lolol. Smaller molecule for NR enters cells in body more readily.
Tru Niagen is NR? is that cheaper?
yes that is a particular form of NR bound with chloride
RENUE beats all their competitors prices. Great company very high quality! Check them out!!
I took a molecule so small it fell right out of my throat
It is not clear: "Take NR it becomes NMN and then it becomes NAD."
Why not supplement with just NAD+?
This is super interesting. Thanks for making this video!
Cheers Cassie Apple, you’re a gem!
This is super interesting. Thanks for making this video!
Thanks Cassie Apple, I’m glad you enjoyed it