Cell differentiation | Fate specification | Specification vs determination | Developmental biology
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- Опубликовано: 7 сен 2024
- This video talks about Cell differentiation and cell fate specification. This video will give an overview of the specification vs determination process which is key to understanding developmental biology.
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Sir, can you please make a video on analysis of quantitative real time PCR data?
Perfect video thank you so much. You explained it very well in an easy to understand way.
dev bio playlist ruclips.net/p/PLKtiwIJ8Q7rruflUezPJV0pZBIKLmEJE_&si=ajw8NRt5iQ_OfAXo
this was exactly what I was looking for, thank you!
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What a Perfection ...to the next level.... Hat's 📴 to your patience, that too in Educating ...
You really have inspired me to do better in Teaching Biology..
Thank you so much .. 📚📚📖📖 🖋️🖊️
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@@animatedbiologywitharpan Thank you for the video. This flashcard is not on facebook. Where can we access this? Thank you.
this video just saved my life 😀
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God bless you InshaAllah.very nice video 👌🏻
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Congratulations! I am amazed at the didactic and straightforward way that you can convey the topic. I have been teaching this topic, but I have been inspired by you to improve my class. Thanks for sharing your talent with the world
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Please share among students
1:03 “or neuron reverting back to a stem cell”
What about reprogramming?
@@YairHach yes reprogramming is possible with Yamanaka factors. Basically a set of 4 transcription factors could be expressed to change the fate of differentiated cells into stem cell. this is the basis of induced pluripotency.
@@YairHach please check out our entire dev bio playlist
Why autonomous condition is under the category of specification? Why it's not *autonomous determination* ?
could you please elaborate , we did not get your question properly
@@animatedbiologywitharpanif a cell or group of cell has autonomous specification which actually act as determined cell; if whatever the circumstances it will achieve its fate. Then why it is called autonomous specification, why it is not called autonomous determination.
what about dedifferentiation??
Great job
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Awesome content
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Is it like master regulatory transcription factor is the key for advancing the cell into determined stage of division?
Yes...it is one of the way not the only way. There could be tons of other mechanism that can drive the deterimination.
Nice video
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Thanks
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Hey please help me... Can you tell me what to study under the heading "tag based enzyme purification "... Can't find this topic anywhere.. Please reply as soon as possible... Thank you 🌻
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Its basically affinity purification ruclips.net/video/DgtpnXZz4wQ/видео.html
Thank you so much 🌻💌
Enzyme engineering by site directed mutagenesis... Link for thiss topic? If you have .
Sir, what is the problem, addressing which through research, would make these transplantations possess medically feasible...?
I we don't normally imagine someone who lost his hand in an accident have a new hand transplanted from his own iPSC... or the skin of a Man has burnt and new skin is transplanted...
Is there any area researchimg on which make it feasible...?
One thing I would like to add... Cancer is said to be the main disadvantage behind stem cell Therapies... is it the only problem...?
Where does the cell get the information about differentiation?
In cell fate specification, signaling centers play pivotal roles by secreting molecules that influence nearby cells. These signaling molecules, often proteins or growth factors, bind to receptors on target cells, initiating a cascade of intracellular events. This signaling cascade can activate or repress specific genes, determining the cell's fate, such as differentiation into a specific cell type or remaining undifferentiated. Notable examples include the notochord in vertebrate development, which secretes Sonic Hedgehog to pattern the neural tube, and the organizer region in early amphibian embryos, producing Noggin to regulate neural and mesodermal differentiation. Signaling centers are crucial for orchestrating complex developmental processes.
@@animatedbiologywitharpan I'm aware of morphogens but that's not what I was referring to. The signalling process is either random or deliberate. It's obviously not random since we don't have a foot sticking out of our foreheads. But if it's deliberate then there must be a source of information that determines morphogen behaviour. Also, do we know exactly how information is transferred between morphogens and cells (DNA)? As I'm researching this question I find it bizarre that so much is taken for granted but not entirely understood. The science on the mechanism of DNA expression sounds like there's so much of it that is unknown that it's hard to make definitive conclusions. Thank you for your answer.
Very bad explanation
Thanks for your feedback