Factors Shifting Oxygen Hemoglobin Dissociation Curve

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Video Summary:
It's recommended that you watch the first video on oxygen hemoglobin dissociation curve before starting this video. All the basic are covered in that video. In this video we are focusing on the shift in oxygen hemoglobin dissociation curve. This video is in two parts. First I have mentioned how the binding of oxygen with hemoglobin is affected with shift in the curve. Here I have avoided siting any examples. Then in second part, we will see factors that shift the curve. Here we have increased temperature, carbon dioxide, hydrogen ion and 2,3 DPG which shift the curve to left. Shift in curve to right by increased carbon dioxide and hydrogen is also called Bohr's effect. It helps deliver more oxygen to tissues. 2,3 DPG level is increased in hypoxia and it helps in adaptation to it. Carbon monoxide shifts the curve to left. It increases affinity of hemoglobin so much that hemoglobin don't release oxygen at peripheral sites, depriving the tissue of oxygen.
🎞More videos on Respiratory Physiology:
● Transport of Gases
- Oxygen Hemoglobin Dissociation Curve: • Oxygen Hemoglobin Diss...
- Factors Shifting Oxygen Hemoglobin Dissociation Curve: • Factors Shifting Oxyge...
- Oxygen Hemoglobin Dissociation Curve during Exercise: • Oxygen Hemoglobin Diss...
- Transport Of Carbon Dioxide: • Transport of Carbon Di...
- Carbon Dioxide Dissociation Curve: • Carbon Dioxide Dissoci...
- Haldane Effect: • Haldane Effect in Tran...
● Lung Mechanics
- Alveolar Pressure and Pleural Pressure: • Alveolar Pressure and ...
- Surface Tension in Lung Alveoli: • Surface Tension in Lun...
- Surfactants Mechanism of Action: • Surfactants Mechanism ...
- Functions of Surfactants: • Functions of Surfactan...
- Compliance of Lungs: • Compliance of Lungs
- Diseases Affecting Lung Compliance: • Diseases Affecting Lun...
• Ventilation & Dead Spaces in Respiratory Tract: • Ventilation & Dead Spa...
• Lung Volumes and Capacities: • Lung volumes and capac...
• What Determines Lung Volume?: • What Determines Lung V...
00:00 Introduction
00:21 What a shift means
02:38 Factors shifting the curve
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DISCLAIMER: This video is for education purpose only. Although every effort is made to ensure accuracy of material, viewer should refer to the appropriate regulatory body/authorised websites, guidelines and other suitable sources of information as deemed relevant and applicable. In view of possibility of human error or changes in medical science, any person or organization involved in preparation of this work accepts no responsibility for any errors or omissions or results obtained from use of information in this video.

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[@adarshpagad427]

I've been trying it since 1st year , now i got crystal clear about the topic

[@alexanderalexander7476]

Thank you. I saw many videos to understand this concept. And now... i found this video and the topic is very clear.

[@ifraamir2783]

Highly appreciated .very easy to understand in such short time

[@prof.dr.habibrehman7354]

One of the best clip I would say even clear my concept. Congratulation for making so much informative video along with learning materials in a very short time

[@NonstopNeuron]

Thanks a lot!

[@arshithgowda8728]

@@NonstopNeuron sir does the dissolved O2 perfuse tissues

[@arshithgowda8728]

I mean unbounded oxygen with hemoglobin

[@sangrams]

Greatly simplified explanation.....time saving and confidence boosting 👏

[@adityamane7084]

Sir hats off to you, you are changing the course of learning and education!!

[@NonstopNeuron]

Thank you Aditya. The motto is to make medical education as easy as watching cartoons. Hope we succeed. 😊

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Excellent description

[@NonstopNeuron]

Thanks!

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It was the best class I have ever seen on this topic! Thank you so much.....

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Great explanation, thank you

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after 4 years of studying i finally understand this, tysm

[@aejhae1]

This is on point! Clear and concise.
Thank you very much!

[@NonstopNeuron]

Most welcome. Please share the video. We need your support. Thank you 😊

[@LeviAckreman-jf3bg]

Awesome explanation

[@thedesidoc1377]

I wonder how this topic bcm so simple when it's in cartoonists form and when it's made by non stop neuron ,anyway proud to hit the 1st like

[@NonstopNeuron]

That’s exactly the goal of my work “to make the medical education as easy as watching cartoons”. So such complements mean a lot. If you are enjoying it and want to support, please share the videos with all your friends and colleagues too. Thank you.😊

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You made Learning medical concept as easy as watching cartoon ❤

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Wonderful explanation

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Thank you sir.

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thanks a lot, this is the best vid i v seen about this topic

[@NonstopNeuron]

Welcome 😊

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Superb...

[@UPHROSHAN]

Thanks a lot for this video

[@NonstopNeuron]

Most welcome 😊

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Thanks for giving good concept

[@NonstopNeuron]

Welcome😊

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[@NonstopNeuron]

Most welcome

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Thanku.. For ur wonderful explanation☺️❤️

[@NonstopNeuron]

My pleasure 😊

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[@NonstopNeuron]

Bahut bahut dhanyavad Sharmaji🤗

[@medicinskomail9376]

Very good but the example with CO is not the best choice since CO also shifts the curve down... Better example is Fetal hemoglobin ...

[@s.rishteee]

Thank you so so much sir but🤍 ......is that much detailed questions comes under NEET or cbse board papers ?

[@ghostoflego3390]

Sir i have a doubt. You say that carbon monoxide increases affinity for oxygen in haemoglobin. But isnt carbon monoxide itself suppose to attach with haemoglobin( forming carboxyhaemoglobin ) and prevent oxygen combining.

[@NonstopNeuron]

I will have to re-check the textbooks I referred.

[@DrAK-ex6do]

Wow

[@user-rx5zd2um3g]

First time I have fully understood this. I guess that’s why they say to read Ganong but in reality med students chose to learn from other books which are less time consuming but skip on the core concept making.

[@NonstopNeuron]

I am glad it helped 😊

[@jeni3486]

❤❤❤❤

[@AjaibMohamed]

❤

[@abdulrahmansyed7608]

Do partial pressure of O2 affects the shifting of curve

[@NonstopNeuron]

the curve is recorded at different pressure of O2 itself. The partial pressure is fundamental factor to produce the curve whether shifted or not. Then we study effect of different factors how they affect O2 saturation at different partial pressures. I hope you are getting it.

[@sanjusikarwar8002]

thank you.... You don't know what this mean to us 🙂

[@pihuupanwar1994]

Very nice sir. Per bht fast h..

[@NonstopNeuron]

Fast speed is deliberate so that you can revise quickly. Still you can use speed control feature of RUclips as per your confirt.

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get lost then 😂😂