Coagulation Cascade and Fibrinolysis - clotting factors, regulation and control mechanism

"The classic coagulation cascade is divided into the extrinsic and intrinsic pathways which both lead to what is called the common pathway. The hallmark of both intrinsic and extrinsic pathway of coagulation is the sequential activation of a series of clotting factors. Clotting factors are shown as Roman numerals, and numerals followed by the alphabet represents an active clotting factor. For example X --: Xa (Xa being the active factor)
The classical view of coagulation is very useful to interpret coagulation tests and identifying bleeding disorders based on coagulation factors. However physiologically the coagulation cascade is much more confusing. There is a cell based model of coagulation which involves 3 steps: initiation, amplification and propagation."
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[@DoctorLokeshprabhakar]

Keep doing your work, and please upload atleast 2 or 3 videos if you have time. No pressure on you sir. I'm in medschool, currently watching your whole videos. It's helping me a lot, even if it's posted 9 years ago. Love you from INDIA ❤️❤️❤️

[@hammerradiology1470]

That's a really nice comment :) Hi to a future colleague from Germany! 🖐

[@hammerradiology1470]

This topic is quite hard or time consuming to learn... Nice presentation! Thank you!

[@sakshambangotra7236]

It's pretty hard
But I wanna tell you that our professor finished it in barely 20 minutes
But now I think I learned at least 40% of it in 1 go

[@princess_katana]

This is better than my class lectures!

[@hammerradiology1470]

RUclips is awesome because we can help each other out :) good luck on your journey!

[@princess_katana]

@@hammerradiology1470 yes 100%, I just saw that you do Radiology videos!! Definitely checking them out 🙂

[@hammerradiology1470]

@@princess_katana Thank you! Started making videos a few months back so I'm learning as I go. :) But each day I think- oh this case would be so useful to put out in the world...

[@49rasalyogesh49]

Thank u sir for amazing video .. clear the concept as well as helpfull for study

[@serenalass5053]

thank you so much, you've made a difficult topic much easier to grasp

[@balaramchowdary9]

Please make more videos, I love your content ❤️

[@shbangash437]

Really love your lecture Sir

[@kindifalon3208]

it was 109 slides and you help me in 10 minutes to understand thankyou☺

[@belieber.isa1234]

LOVED IT!!!!!!! A great class, thank you

[@ramchandrasuthar2848]

GREAT ANALYSIS SIR 👍👏👌🙌

[@mimimbachi4460]

Thank youuu from Nigeria it really helps

[@طبعام-ذ6ف]

Very needed i v stadied hemostasis alone and it was so hard for me, thank you so much .it s a great job i have to revise it more and more

[@curiousmind7143]

Nice explanation sir

[@prasanna4399]

omg waited so long for this, thanks a lot.

[@daksithchandula116]

Superb superb you have exceptional teaching skills 😊

[@dr.jemimah]

Thank you for your video, it was very helpful! Keep up your hardwork

[@stixinst5791]

Almost perfect! Lovely work!

[@ghufran9479]

Thank you so much for this amazing video good job

[@kzgnhulkmuge9084]

Perfect explanation❤

[@shirazsalah8249]

Amazing 👍 love your content

[@medicalbiochemistry_]

Amazing video

[@fatimasuleman1980]

Thank you very much

[@scienceqila3993]

You Rock Sir ❤

[@aazimasultana4807]

pleaseeeeee make a vedio on sinusitis and nasal polyp......your vedios are very helpful.....

[@Mohammad-xe2qw]

Much appreciated ☺️

Tranexamic acid also useful for skin discoloration

[@AnastasiaChatzisavvidou]

Excellent thank you

[@AmilaR1989]

Excellent work :)

[@samadali5532]

Love you man

[@Jay2423M]

still can't understand it but i now know more than i did before this video

[@MsAbby.3]

Same

[@Ahaider22]

Amazing

[@issahssn8273]

If hard headche in chapter I open Armando hadusan easy and best to learn understand

[@Dr_feelgood_zw]

👏 Thank you

[@Lmab-qs1kr]

Tysm

[@dr.shandhanchowdhury3955]

The best . love

[@davidegarzone8699]

great content. May I ask you how do you make your videos? is it with Doodly? THanks.

[@uroojaarif9943]

The Best

[@syedidrisahmed17]

Can you make chemistry related videos.

[@syedidrisahmed17]

Like,
Human anatomy and physiology,
Pharmaceutics and
Medicinal biochemistry.

[@hammerradiology1470]

Radiology?? :)

[@machipeurangkau1528]

Sir... Is coagulation cascade and coagulation of blood same??

[@tak2malay24]

Yes

[@flowaagurl1396]

This is great! As constructive criticism- it was unable to be heard at 7:36 if you were saying TFPI inhibits tissue factor and ____? I’m guessing 7a
Overall ur amazing, thank you!

[@1aliveandwell]

Anylabs if chilblain when chili?

[@alexandracastelorosa9664]

I cannot find the PDF on the shop for this? Help?

[@willenova]

Factor elöven

[@gaylecheung3087]

Wow way to Advanced for me

[@ma_kau_]

Beautiful 😍😍😍😍😍😍

[@comemucho5599]

Is collagen a factor of fibrosis?

[@Pathologyformedicalstudents]

An excess in collagen production is necessary for the development of pulmonary fibrosis. The cells responsible for collagen production are believed to be fibroblasts and myofibroblasts

[@LuckeyClover]

Man this crap neverfails to scramble my brain, that's just way too much info to ingest in one sitting, like this go back and fourth back and fourth and around, and than back to the middle😵‍💫😵‍💫I'll never get it lol

[@rishiraj9131]

🙏👍👍

[@clinicalpediatrics]

1st view! Lol

[@walaadabbas9354]

🥰🥰🥰🥰🥰

[@misakostic2524]

Not practical, confusing (i bet the author needs some clinical and more practical assay approach before making this video)

[@tethkaromar9252]

Thank you very much

[@adhyssuzie1129]

Amazing