Donnan Equilibrium

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  • Опубликовано: 31 дек 2024

Комментарии • 215

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 года назад +3

    🧫 Antibiotics Lectures: www.medicosisperfectionalis.com/
    🧪 Electrolytes Course: www.medicosisperfectionalis.com/

  • @mohitkandari6085
    @mohitkandari6085 4 года назад +101

    When you understand something rather than learning something, you remember it for life. Thank you dr for helping me understand.

  • @nidhig2644
    @nidhig2644 3 года назад +20

    Cannot explain how good it feels to finally understand. You sir are godsent.

  • @azalkibsi
    @azalkibsi 3 года назад +28

    This is just amazing, Never enjoyed a medical video such as this one. Thank you for your hard work Dr.

  • @soumiaboudjemaa1179
    @soumiaboudjemaa1179 3 года назад +17

    this is just incredible
    i really appreciate your efforts , thank you so much for making me not just understand , but also laugh the whole video
    you litterrally made my day

  • @angeljacob4620
    @angeljacob4620 3 года назад +5

    searched for this topic and just came across your video...It's the best video I have ever seen in my life !!!! THANK YOU!

  • @dynamite_being
    @dynamite_being Год назад +6

    Simple and effective explanation is a symptom of someone highly perfused with knowledge📚

  • @deae3831
    @deae3831 5 месяцев назад +2

    I feel like im having a conversation with out saying anything. I love this, thank u dude

  • @ahmedkoraichi997
    @ahmedkoraichi997 Год назад +2

    U're just helping us to be great doctors thank uuu

  • @bionium6976
    @bionium6976 2 года назад +2

    Sir i love you , i mean this channel is sucha boon to mee like i understood this concept so well , im a medical student from india i like your accent as well, like so active and inclusive

  • @rijakhalid9011
    @rijakhalid9011 4 года назад +14

    OMG you're amazing! Hope you can be the next Dr Najeeb hehe

  • @r.bishvajeet2820
    @r.bishvajeet2820 6 месяцев назад +3

    Love from India...explained well❤

  • @rs6731
    @rs6731 3 года назад +4

    This was just magic..great work sir!!

  • @pratikshyalamichhane4326
    @pratikshyalamichhane4326 4 года назад +5

    Ohh my god , I can feel the tone of my professor's today's class about this topic. And it was freaking same as medicosis explained how proffessors do .

  • @mataboras4816
    @mataboras4816 11 месяцев назад +1

    A really great video that helped a lot with understanding the concept. Much thanks!!!

  • @rigormortis6981
    @rigormortis6981 4 года назад +4

    I wasn't even listening attentively but I understood it! Amazing!

  • @joeramirez2156
    @joeramirez2156 3 года назад +3

    That’s legit! Love it man. Keep up the awesome work.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      Thank you so much 😊

    • @joeramirez2156
      @joeramirez2156 3 года назад +1

      Yeah currently doing nephrology as I type this...you broke down some really good topics. I’ll def. be using your channel to help get through future blocks!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      Awesome 👏
      I am honored!
      Thank you 🙏

  • @vadimushakov5883
    @vadimushakov5883 2 года назад +2

    Greatest explanation of one of the hardest blocks in medicine. Cheers!

  • @bhatshahid5214
    @bhatshahid5214 4 года назад +3

    Really unparallel
    Thank you sir
    Keep shining

  • @thekingofsomething
    @thekingofsomething Год назад

    I appreciate your work, though I have a couple inquiries
    Facilitated diffusion includes a channel thus it shouldn't be simple diffusion, it should be either the umbrella term passive transport or the more specific term facilitated diffusion. Secondly, regarding volume replenishment, when dehydrated you feel thirsty and havenmuscle cramps, the cells shrunk in the hypothalamus and muscle cells lost water respectively. Thus you can't only think of the IVF and Interstitial fluid alone when rehydrating, after all if water is lost, some ICF will help the ECF. Unless the patient you mentioned had absolutely normal water volume

  • @justsamira4477
    @justsamira4477 4 года назад +5

    Hi life saver.. thanks alot i loved this lecture.. it's very useful.. I'm preparing for USMLE step 1 🌹👍🏼

  • @CLEMENCEEELIAS
    @CLEMENCEEELIAS 3 года назад +7

    8 Na+ ions are needed in the protein component

  • @anastasia2162
    @anastasia2162 3 года назад +1

    OMG that is the best explanation ive seen so far!!

  • @aridjb1302
    @aridjb1302 4 года назад +2

    You save my life!!, tnx so much 💚😍

  • @gaebu68
    @gaebu68 10 месяцев назад

    5:46 I don't understand why the sodium would want to go to the left. Surely, there are more negatives on the left to attract it, but also the exact same amount of positives to repel it. So why would you say that still overall it wants to go to the left?

  • @snehamasuna8745
    @snehamasuna8745 3 года назад +3

    Loved the way you explain ❤️❤️❤️❤️❤️❤️❤️❤️

  • @sheetalmahajan4150
    @sheetalmahajan4150 4 года назад +2

    Perfect explanation

  • @naaengmann2117
    @naaengmann2117 4 года назад +11

    8 Na+ ions?

  • @jeroendewaal2652
    @jeroendewaal2652 Год назад +1

    why isn't the example with "before equilibrium" also at equilibrium?
    The electrical gradient and the concentration gradient are both at 0 between the protein component and the non-protein component.

  • @hinamushtaq1757
    @hinamushtaq1757 2 года назад +1

    Awesome.... it cleared my all doubts

  • @raaishzeeshan
    @raaishzeeshan Год назад +1

    It was a blessing to scroll and tap on it.. just love the way of teaching. Last mint preparation of exam 😅 hope to deal with exam way more better.. thanks for this one

  • @doughnut469
    @doughnut469 Год назад

    One question. When Water flows to the Protein compartment, wouldn't it dilate the Ion concentration thus the Donna's Equation would never be stable and Water would flow to protein compartment until the cell looses all his water and die from lack of wetness or from greediness of the thirsty protein compartment? I feel like Donnan must be stopped

  • @sayanibasu__
    @sayanibasu__ Месяц назад

    8 Na+ ions, btw thank you for such a nice explanation

  • @rayansyed1714
    @rayansyed1714 4 месяца назад

    thank you medicosis. The answer is 8 Na+.

  • @keziaint1533
    @keziaint1533 Год назад

    wait soo like the donnan effect happens when there is hypoperfusion in the body?

  • @mrtenbbh1670
    @mrtenbbh1670 Год назад

    So good i really enjoyed your teaching.

  • @xavierxrc
    @xavierxrc 10 месяцев назад

    Is there something I'm missing? The protein content in the body is higher intercellular than extracellular. So water will want to move inside the cell according to this. However, it's extracellular sodium that prevents this.

  • @dr.amitgupta_
    @dr.amitgupta_ 4 года назад +2

    Amazingly explained 😍😍😍

  • @nidhig2644
    @nidhig2644 3 года назад +1

    Small doubt - plasma volume is around 5L and total body volume 42L. Doesn't that make the ratio 1/8th instead of 1/4th? Since whatever fluid we administer being isosmotic will get equally distributed between ICF and ECF?

    • @DrApurvaCV
      @DrApurvaCV 3 года назад

      I have the same doubt

    • @AhmedMostafa-hl9yl
      @AhmedMostafa-hl9yl 2 года назад

      okay...
      firstly, plasma is 3.5L and it represents 5% (3.5/42) of total body water
      Secondly, Fluid wont move if no one tells it to, its lazy. Fluid moves from plasma to Interstitial fluid due to hydrostatic pressure, but to move to ICF, it would need osmotic pressure. The infused fluid is isotonic which means it has same osmolarity as ICF, so there is no osmotic pressure, so water will not move into the cells or we would all be dead from our cells bursting doofus. Joking, sry

  • @d00mch1ld
    @d00mch1ld 2 года назад +3

    What the flip? This is the best explanation I have ever seen.

  • @mohamedabomera5598
    @mohamedabomera5598 4 года назад +2

    Can I get the chance to work with you as a translator to your content ?
    I am a medical student from Egypt

  • @SaraAhmed-gx2jd
    @SaraAhmed-gx2jd Год назад

    Please doctor, what's the application that you use 😊❤

  • @sburns90
    @sburns90 4 года назад +4

    Wow, I wish some of the doctors I have dealt with in the past have watched your videos. If they did my family would probably be in much better health. I may have to show this to my family member's doctor, lol.
    I have some family members whose doctors don't understand dehydration and hypoperfusion, or so it seems. They say just drink more water (which makes it worse due to lack of electrolytes) and they assume it's normal to have low blood pressure, hypo-osmolar blood osmolality, Reynolds like phenomenon, dizziness, fatigue, dry skin, dehydration, and adipsia.
    Then even when we tell them plain water generally makes symptoms worse, then their answer is well all you need is more water. 😲

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +2

      It’s sad 😔

    • @sburns90
      @sburns90 4 года назад

      @@MedicosisPerfectionalis what's really sad is the 8+ doctors from different medical disciplines, different health systems, and different states who still say drink more water. Even though it is plainly obvious the person is experiencing hypo-osmolality hypo-perfusion.
      It seems it is just too much to ask to get several liters of fluid to fill the cellular compartment and improve tissue perfusion.
      What a shame.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      You’re right, bro

  • @smdr5576
    @smdr5576 4 года назад +3

    DOPE! Thanks a lot!! very well explained

  • @jessjames5530
    @jessjames5530 3 года назад +2

    Thanks😊🙏🙏this was so good🙌🙌
    You sound like L Lawliet from Death Note😍🔥🔥🔥

  • @Qamaramed
    @Qamaramed 8 месяцев назад +1

    Un grand merci à vous , où je peux trouvez la 2ème vidéo pour savoir la réponse ? C est quelle playlist ? X= 8 ( avec 6 protéine dans plasma ?)

  • @eloischill1391
    @eloischill1391 3 года назад +1

    my woke irl professor has failed me and i needed this SO BAD thank you so much

  • @rudramodha6048
    @rudramodha6048 2 года назад +1

    What!!!!! You know Dr najeeb 😱

  • @Qamaramed
    @Qamaramed 8 месяцев назад

    Please what's the name of this playlist ??? 😊😊

  • @ranjitk9115
    @ranjitk9115 2 года назад +1

    The non protein compartment should be interstitium not cell. Gibbs donnan equilibrium is actually explained btw protein compartment (cell) and non protein compartment interstitium. Am i correct. Plz correct me if am wrong.

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад

    👨‍🏫 Physiology Playlist: ruclips.net/p/PLYcLrRDaR8_eAjmngd289ghWijs2wfqnj

  • @melomane6936
    @melomane6936 Год назад

    Is x=3
    Thank you for the video 😊

  • @abhisheksharma0426
    @abhisheksharma0426 3 года назад +4

    Your heart 💓 is history
    Your brain 🧠 is a mystery
    Your kidney is screwed
    Epic😂

  • @astaghfirullah10000
    @astaghfirullah10000 2 года назад +2

    شُكراََ جزيلاََ .

  • @janakayed7536
    @janakayed7536 Год назад +1

    Thank youuu so much !!! Couldn't have been clearer :)

  • @stevenshine6116
    @stevenshine6116 4 года назад +2

    This is AWESOME!!

  • @MohammadRezaFayyazi-c8s
    @MohammadRezaFayyazi-c8s 4 месяца назад

    I think the first consequence isn't correct. In the picture "after equilibrium", there is no electrical gradient because the electrical sum of ions in both sides is zero. And the only force on sodium is just the chemical gradient which leads to disturbance of equilibrium😕
    I think what is showed as equilibrium is wrong

  • @heartcomedy5
    @heartcomedy5 4 года назад +3

    Great video 👍

  • @gerlaxhelili422
    @gerlaxhelili422 4 года назад +2

    Thank you! Great video

  • @fatimabushra1758
    @fatimabushra1758 3 года назад +5

    Thanku Dr for such a nice explaination..
    8 Na+.

  • @mobenkane2075
    @mobenkane2075 3 года назад

    Isn’t that #1 is facilitated diffusion? Because Chloride is facilitates through protein channels.

  • @indu6629
    @indu6629 3 года назад

    Excellent explanation...

  • @johnmarston8532
    @johnmarston8532 3 года назад

    Everything is superb except too many ads which destroy the focus on the topic...if possible, please try to fix.

  • @hewaahmedmustafa8027
    @hewaahmedmustafa8027 Год назад +1

    You have a mistake, I think .
    what about Donnan Electrical Potential?
    If ions are equal in both sides there will be no electrical potential.

  • @qondohmbokwana9013
    @qondohmbokwana9013 3 года назад +1

    "all kinds of gains"- The Hodge twins

  • @ankitasaha7425
    @ankitasaha7425 4 года назад +1

    First one yaay! Haven't watched video though . 😂
    Watching ...

  • @CHEH_tf
    @CHEH_tf 2 года назад

    Bro thank you for this

  • @ankitasaha7425
    @ankitasaha7425 4 года назад +4

    At this point I have only one confusion if I should call you Dr Sir or Sir Dr :) It's because you are a great teacher and I guess rather I'm sure you are a doctor too .
    Anyways video was great understood everything ! ✨

  • @roro47308
    @roro47308 3 года назад +1

    +8 particales of Na

  • @karthikisr8
    @karthikisr8 9 месяцев назад

    it's like Rowan Atkinson's teaching me

  • @oxell4925
    @oxell4925 3 года назад

    I think the answer to the question is 8 Na+ ions!

  • @abdeldjalilbenaissa3397
    @abdeldjalilbenaissa3397 2 года назад

    earned a sub brother

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  2 года назад

      Thank you 🙏

    • @abdeldjalilbenaissa3397
      @abdeldjalilbenaissa3397 2 года назад

      @@MedicosisPerfectionalis really you should know that you are helping people from all the world to become doctors and we apperciat what you doing love from algeria

  • @drramoray9057
    @drramoray9057 4 года назад

    Bro make vedios on cvs .
    Request bro.

  • @nayantarabiju1928
    @nayantarabiju1928 2 года назад

    Thank youuuu😭

  • @ahmedmousa3358
    @ahmedmousa3358 Год назад +1

    ابداع🔥

  • @maimuna20
    @maimuna20 2 года назад +1

    So cool 🧡

  • @mahbubamaria1742
    @mahbubamaria1742 4 года назад

    Will the value of "X" be 14?

  • @ashujnn
    @ashujnn 4 года назад

    How to increase platelet count through food. My father tested positive for covid 19.he is normal.his platelet count is 60000, daily it is fluctuating.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      Hey Ashu.
      I am sorry to hear that...It must be hard on the family.
      Does your father have bleeding symptoms?

    • @ashujnn
      @ashujnn 4 года назад

      @@MedicosisPerfectionalis no bleeding. No temperature

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      Talk to the doctor, because the lack of bleeding symptoms may require no treatment for the 60,000 platelet count.
      Other labs need to be taken into account...Please talk to his doctor!

  • @riyatripathi6893
    @riyatripathi6893 9 месяцев назад

    8 sodium ions

  • @nanneboyinapranavi1060
    @nanneboyinapranavi1060 3 года назад

    x=8 because the produt equals that is 2'x=16 x=8

    • @vishantsingh325
      @vishantsingh325 2 года назад

      what about+ve = -neg in each compartment?

    • @srijoni1237
      @srijoni1237 2 года назад +1

      @@vishantsingh325 they match too . There are 6 plasma proteins and two chloride ions so 8 neg so there must be 8 positives

    • @vishantsingh325
      @vishantsingh325 2 года назад +1

      @@srijoni1237 ah yes. :) Thank you Bear

    • @vishantsingh325
      @vishantsingh325 2 года назад

      By any chance, are you from Water field?

    • @srijoni1237
      @srijoni1237 2 года назад

      @@vishantsingh325 If that’s a place then I’m sorry I haven’t heard of it.

  • @hansmenares3850
    @hansmenares3850 Месяц назад

    science and capitalism, my favorites :)

  • @laxmihalam6068
    @laxmihalam6068 Год назад

    Now let's go to wisdom baby❤...fallen in love with you sir
    Okay so I must say this video is just awesome...thank you soo muchhhh

  • @dungnguyentrung8135
    @dungnguyentrung8135 3 месяца назад

    nice bro

  • @partomeraji3084
    @partomeraji3084 3 года назад

    briiiiiiiiiiiiiiiiiiiiilliant

  • @snehamasuna8745
    @snehamasuna8745 3 года назад +1

    The answer is 8

  • @bichadiva6717
    @bichadiva6717 3 года назад +1

    U R A LEGEEEND
    IT TOOK ONE LECTURE AND MANY HOURS BEHIND WRITTEN LESSON AND STILL DIDN'T GET IT
    MEANWHILES I COULD GET IT IN 15 MIN
    🤯🤯🤯
    Edit: btw answer is 8 Na+

  • @aneesmusic7174
    @aneesmusic7174 3 года назад +1

    Answer is8

  • @drpepper7801
    @drpepper7801 3 года назад +3

    Lol first time watching your videos... You have a sharp mouth lol

  • @mukajii
    @mukajii 24 дня назад

    My answer is 8 Na

  • @sevinch6304
    @sevinch6304 3 года назад

    N o i c e

  • @jeskaisekai_6785
    @jeskaisekai_6785 4 года назад

    X= 8

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад

      Why?

    • @jeskaisekai_6785
      @jeskaisekai_6785 4 года назад +2

      @@MedicosisPerfectionalis becuase the product of NaxCl in the protein compartment is equal to the product in the non-protein compartment so 2×X=4×4 -> X=8. Also the difference of Na and Cl in the protein compartment is 8-2=6 and this excess of positivity is balanced by the 6 (negative) plasma protein particles in the protein compartment. (I think this is the right answer but anyway I really wanted to thank you, even if english is not my first language I find very easy and enjoyable to watch your videos; this channel is a blessing xD)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +3

      Awesome 👏
      You’re excellent!

  • @excitementsoflife5110
    @excitementsoflife5110 8 месяцев назад

    8

  • @Apostate_ofmind
    @Apostate_ofmind 2 года назад

    bloody hell, i understand

  • @joseireyessoto9747
    @joseireyessoto9747 4 года назад

    I can't find your name :( Whoa are you?

  • @sat1327
    @sat1327 4 года назад +1

    Wow

  • @aminaassbayou85
    @aminaassbayou85 3 года назад +1

    i love you

  • @rolf6868
    @rolf6868 2 года назад

    Damn myself if this video isn't perfect XD

  • @arathy592
    @arathy592 3 года назад

    Plz give me class...and not qnz..plzz🥺🥺😁😁

  • @yumxhtutkai8591
    @yumxhtutkai8591 3 года назад

    Ohh eight

  • @mohamedazaarudeens1311
    @mohamedazaarudeens1311 2 года назад

    8 Na

    • @mohamedazaarudeens1311
      @mohamedazaarudeens1311 2 года назад

      Product of Na and Cl inside protein compartment= product of Na and Cl inside non protein compartment
      2 x X = 4 x 4
      2 x X= 16
      X= 16/2 = 8