this was an absolute godsend, I was trying to relate fatty acids structure to their role as energy storage molecules and everything was coming up blank until i found out I needed to be looking at oxidation, thank you so much!!
WOW! This is my first time knowing why fats can give more energy than glucose. Although it sounds intrinsic, I never know why this is the case. Brilliant video, thank you Rana. :)
That 107 ATP comes from merely from oxidation! If we added the ATP from each ETC that runs after the acetyl CoA. OMG!!! That's really a lot. I've never thought of fats can be that powerful, comparing only about 32 ATP produced from glucose.😂👍
Even though is not in this video, but I recognised your voice. thank you so much! You helped me aced my test. You are voice is so calming and it feels so easy listening to your explanation🥺💜
Do the fatty chains turn into an exact amount of Acetyl-CoAs that we need or do we just produce a whole bunch of acetyl-coa which will return into fatty acids if we don't use them?
Good question. I believe beta oxidation will continue until all you have are Acetyl-CoAs. Then they can be used in fatty acid synthesis or ketone metabolism
Absolutely not, but they're close to the same, the only variation is about 1/2 ATP. Keep in mind also that the ∆G of this will also depend on the molecular makeup of the Fatty Acid Chain. Things also like Substrate availability, efficiency of the ETC, and overall mitochondrial health of the subject. If you like this subject, Harvard University offers a free course in Biochem that is VERY challenging.
So are ATPs what we use to burn calories? Does 1 ATP allow us to burn exactly 1 calorie? What happens if we have a lot of ATP? Where do we store it? Is body fat our main stored source of energy for times of need? Where else do we hold energy?
ATP is adenosine triphosphate, it is the energy currency of cells in the body. Think of it like money, you have to go to work to make money, if you don't have money you can't go have fun. Similarly with low ATP synthesis your cells don't have the free energy ∆G to do work (have fun). ATP doesn't burn kCal what you're talking about are two different functions. You've got it kinda backwards, the burning of the kcal in your body is what leads to the oxidation and phosphorylation of glucose and then produces ATP, so that your cells can live. Does this help, three years too late? lol
technically it should be considered acyl-coA since it helps in the metabolism of fatty acids rather than helping in protein and carbohydrate which acetyl-coA does
is the 27 ATP portion from the fatty acid chains or from only the kreb cycle? because kreb cycle produces 8 NADH, 2 FADH2, and 2 ATP. When you do the calculations and stuff it equals to 27 ATP. But when you do calculations for the fatty acid chain, it's also 27 and so i'm a bit confused because i know the number also depends on the length of the fatty acid chain.
@@jannthomas7915 From what I've read, 1 Acetyl-Coa produces 10 ATP as it moves onto Krebs (into the cycle itself). But before that, while it is still going through the beta-oxidation stage, it produces a net ATP count of 2 ATP as it needs 2 ATP to activate the fatty acid and beta-oxidation produces 4 ATP (1 FADH2 + 1 NADH). I think the 27 ATP comes from the beta-oxi stage (16 C = 8 Acetyl-Coa = 7 cycles of beta-oxidation) while the 80 ATP comes from the 8 Acetyl-coa entering Krebs.
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lightyears better than the teachers at my school. please keep making these
this was an absolute godsend, I was trying to relate fatty acids structure to their role as energy storage molecules and everything was coming up blank until i found out I needed to be looking at oxidation, thank you so much!!
Thanks! Your videos on fatty acid oxidation/synthesis are so good! I love how you explain the big detail, I learnt a lot from it!
omg first person to do this type of lecture with nice handwriting!
Love every minute of this . Keep it coming
I appreciate this resource. Much love and thank you.
Great video with explaining the process step by step. Much appreciated.
WOW! This is my first time knowing why fats can give more energy than glucose. Although it sounds intrinsic, I never know why this is the case. Brilliant video, thank you Rana. :)
Than you very much. I appreciate what have you done :) .
Really clear explanation. Thank you!!
Exactly what I was looking for thank you!!
beautiful, thank you!
OK you guys are really good
Way easier to understand than other movies 5 star narration.
beautiful! thank youuuuu x
Thanks a lot.... I'ts so amazing !!
Excellent explanation thank you
In order to have the net ATP's shall we deduct 1 ATP from the step of conversion of fatty acid to Acetyl CoA?
You’re the best!!
You are the best 💖
Omg she sounds so adorable! I didn't understand anything...
Lol
Yah her voice is seducing...
😂😂😂😂😂😂😂😂😂😂😂😂
😅🤣🤣🤣😂😂
The green color makes difficult to follow up
That 107 ATP comes from merely from oxidation! If we added the ATP from each ETC that runs after the acetyl CoA. OMG!!! That's really a lot. I've never thought of fats can be that powerful, comparing only about 32 ATP produced from glucose.😂👍
Even though is not in this video, but I recognised your voice. thank you so much! You helped me aced my test. You are voice is so calming and it feels so easy listening to your explanation🥺💜
Do the fatty chains turn into an exact amount of Acetyl-CoAs that we need or do we just produce a whole bunch of acetyl-coa which will return into fatty acids if we don't use them?
Good question. I believe beta oxidation will continue until all you have are Acetyl-CoAs. Then they can be used in fatty acid synthesis or ketone metabolism
The fatty acid each produces 8 acetyl coa , and yes the acetyl coa does return into fatty acids through the fatty acid synthesis pathway
Do all fatty acids from different sources of fats (saturated, unsaturated, trans) produce the same amount of ATP?
Absolutely not, but they're close to the same, the only variation is about 1/2 ATP. Keep in mind also that the ∆G of this will also depend on the molecular makeup of the Fatty Acid Chain. Things also like Substrate availability, efficiency of the ETC, and overall mitochondrial health of the subject. If you like this subject, Harvard University offers a free course in Biochem that is VERY challenging.
joking grate video
So soothing, the sound....
not at all
why some book 107 106 or 130 ?
Isn't it a total of 108 ATP's?
C16 - 8 acetyl CoA - x 10 ATP's = 80 ATP's
7 NADH x 2.5. = 17.5 ATP's
7 FADH x 1.5 = 10.5 ATP's
sw No its actually 106 ATPs as 2 ATPs were where initially used after mobilisation for activation of the fatty acid before it could be transported
So are ATPs what we use to burn calories? Does 1 ATP allow us to burn exactly 1 calorie? What happens if we have a lot of ATP? Where do we store it? Is body fat our main stored source of energy for times of need? Where else do we hold energy?
ATP is adenosine triphosphate, it is the energy currency of cells in the body. Think of it like money, you have to go to work to make money, if you don't have money you can't go have fun. Similarly with low ATP synthesis your cells don't have the free energy ∆G to do work (have fun). ATP doesn't burn kCal what you're talking about are two different functions. You've got it kinda backwards, the burning of the kcal in your body is what leads to the oxidation and phosphorylation of glucose and then produces ATP, so that your cells can live. Does this help, three years too late? lol
Explain clearly, but actually yield 108 atp from fatty acid oxidation, love your video, keep going
4:25 quantity of atp produced from the oxidation of fat
technically it should be considered acyl-coA since it helps in the metabolism of fatty acids rather than helping in protein and carbohydrate which acetyl-coA does
is the 27 ATP portion from the fatty acid chains or from only the kreb cycle? because kreb cycle produces 8 NADH, 2 FADH2, and 2 ATP. When you do the calculations and stuff it equals to 27 ATP. But when you do calculations for the fatty acid chain, it's also 27 and so i'm a bit confused because i know the number also depends on the length of the fatty acid chain.
How did you get 27?
that's what I wanna know too
@@jannthomas7915 From what I've read, 1 Acetyl-Coa produces 10 ATP as it moves onto Krebs (into the cycle itself). But before that, while it is still going through the beta-oxidation stage, it produces a net ATP count of 2 ATP as it needs 2 ATP to activate the fatty acid and beta-oxidation produces 4 ATP (1 FADH2 + 1 NADH). I think the 27 ATP comes from the beta-oxi stage (16 C = 8 Acetyl-Coa = 7 cycles of beta-oxidation) while the 80 ATP comes from the 8 Acetyl-coa entering Krebs.
1 acetyl coa should yield 12 ATP molecules, not 10.
gotta go birds eye view
It is actually 106 ATP
somehow I'm even more confused?
SA MGA BISAYA ARA NGANO DIAY 10ATP MAN ANG IPRODUCE SA KADA SINGLE ACETYL COA?
Laban hahahahahahahah
kreb cycle, 1 gtp, 1 fadh2 (1.5atp), 3 nadh(7.5) = 10atp. kaya mo yan
bad text color, I can't read them
106ATP not107
What the fuck have I just watched?!
I feel like I learn less because it sounds like I'm being taught by a sorority sister
hey..