Here’s What to Do About VDR Mutations | Chris Masterjohn Lite #44
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- Опубликовано: 22 янв 2018
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Thanks for the info! Appreciate your videos so much, keep up the great work.
Awesome tutorial Chris , well done, cheers. 👍🏽
Thanks for a rational, super simple way to determine your D status. I'm heterozygous for all three VDR mutations and my Vitamin D levels tend to run low or drop very quickly if I discontinue my 5,000 iu supplements. I've never tried looking at my PTH levels before, but have always been interested if I could just get away with using Cod Liver Oil and eating lots of fish instead of synthetic D supplements. It's pretty amazing how being in the sun all day during the summers (without sunscreen) in Utah never seems to alter my status.
Thanks. Great info here.
I have multiple MTHFR snps, and VDR taq. I began taking Douglas Labs B Complex with Metafolin last summer (once, every 72 hours in the morning), and it has completely changed my life (balanced my brain like never before, energy balance, three years of chronic insomnia with months of no sleep and hospitalizations CURED, hypersensitivity down 90%, stress management incredible, etc). I live in a dark place and cannot get enough sun (Portland, OR). Last year I became crazy sensitive to D3 in all oral/digestable forms-gives me gallbladder attacks. I am a 200lb 6'2" male, and I just began taking topical D3, putting it on my feet and in my armpits (only 2000iu) per day, and it has completely brought me out the winter slump that tons of folks are in right now in February/March. I can't recommend looking into either enough. I would love to do a panel with the specifics in this video eventually to see where my balance is now. Thanks, Chris!
is this still helping you? I just tested for the same genetic issues. I am chronic sick with severe fatigue and connective tissue disease
@@Star5dg same with me, in fact my issues were triggered from taking methylated B vitamins even tho it should have helped
@@Star5dg Yes. It has been possibly the most important element in a the holistic approach to healing I've taken.
@@baysick11 This can happen, I've had to go quite slowly with starting my methylation process. If you suddenly start methylating a lot when you haven't, you can place quite a burden on your body without meaning to. Make sure you've got kidney and liver support herbs and whole foods going on, avoiding additives and pesticides as much as possible before beginning to methylate.
@@Contracrostics do you think there’s a way to reverse the damage I’ve done? I’ve continued to get steadily worse the last 5 years
I heard healthy range for Vit D 25 Hydroxy is 60-70 ng/mL (Dr. WIlliam Davis) and that is what I aim for with Vit D3 supplementation. I am homozygous for VDR Taq btw.. no other VDR mutations.
Helpful, thanks.
thanks, i did not know how to assess my vitamin D levels. Will forward this to my doc.
I have VDR TAQ. I'm ordering a Sperti UVB Panel to see if this helps. Right now I'm taking D3 and K2 with it. It feels so much better when I take the D3 and K2, I know there must be something to it.
You should check your vitamin A levels tocopherols/tocotrienols help activate the VDR receptor.
... really?
Which test is best?
Which specific "vitamin A" should I measure?
Source ?
Tocotrienols and tocopherols are vitamin E?
You talk about many ways to cook or store foods without losing nutrients in other videos. Could you possibly talk about how to safely eat high PUFA fish? How do I store or cook them, and where should I buy them from? Should I avoid raw fish? (ex. is canned bad for sardines?) any advice would help =)
carnivore/zero carb??? what do you think of georgia ede and dr. shawn baker?no fiber? plant compounds agitate human physiology?
hi - very interesting. Any update on the Vit A -D3 - K2 ? I have more complex question regarding this when it comes to coagulation …
Yes, I take 160 mcg vitamin K2 (MK7) every day, along with 320+ mg magnesium and 15+ mg zinc.
BTW: magnesium requirements differ for men and women (men need more). I don't know about the other nutrients.
Yes, I'd like info on the vit A & D connection
I have the mutation and an auto immune disease...I take 10000 iu with 200 mcg of k2 a day to up my regulate my T reg cells
Do you also take magnesium?
This is involved in *many* body functions.
Wish 23andme didn't have a shady privacy and ownership agreement.
I've heard the testing with 23andme is not as accurate as it originally was. Or is this just a competitor's opinion?
Does this ultimately come down to taking in more vitamin D than the average? I’m scouring the internet for simple action plans. I’ve found that circumin can increase VD receptors.
Look into Coimbra protocol; short answer is yes, more D. Best of luck
Hi Chris
If you could guess, what do you think the vitamin D and calcium requirements are for African Americans (AAs)? I say this because I am African American and when I take supplemental vitamin d even as little as 1000IU I get bone pains and my skin on my hands starts to break. I do believe that you make a solid point when you state that AAs and other people with darker skin may have an adaptation to require less Vit D and calcium. When you consider the studies such as one that looked at adolescent girls in Baltimore, both black and white, and saw that the AA girls had higher bone mineral density but consumed less calcium and milk products, the primary source of vitamin d in the American diet. I find it ironic that the conclusion of the study was for blacks to increase dairy consumption when the results didn’t reflect it.
Hey Brandon. I would get tested genetically and find out if your VDR's are working properly which it sounds like they are. If you're taking that relatively small amount and have noticeable symptoms my guess is you're getting enough sun/diet to cover your Vitamin D needs. I thought I remember reading long ago that AA's needed more sun exposure because of more melanin. But then again you may be right that AA's have adapted by needing less for that same reason. Hope that helps.
Brandon,
1) I would take less vitamin D3, if you're having those symptoms. Maybe stop for a week. I don't take more than 5,000 IUs at a meal, and typically only once a day.
2) Get a blood test (all three which were mentioned in the video).
3) Are you taking the additional vitamins and minerals to help your body absorb vitamin D?
--> magnesium, zinc, vitamin K2 (MK7)
Does anyone know where in Europe I can do the VDR gene polymorphism check up?
I got mine from 23andMe.
I had two parathyroids removed in 2020 and just found out I carry VDR taq +/+. I’m so curious if this mutation caused the hyperparathyroid issue. I can’t take vitamin D cause it makes me super sick, but all vitamins do. I also have an amine issue (MAOA +/+) so vitamins/supplements are a nightmare for me.
I have the same issue in regards to VDR taq, MAOA, and vitamin D. Still trying to figure this out.
Same!
I think I struggle with vitamin D because it may use up B vitamins in the process (I'm low in b12 too)
I have comt ++ and vdrtaq++ with a long history of low vitamin d even though I eat cheese and fish and meat and get sun(live in California)
Even when I supplement with vit d there’s times it helps my mood so much but others where I feel sick?
And even if the supplementation raises it, the second I stop taking the vit d supplement it tanks rapidly
Anyone have any tips ?
Should I just take more vit d and pair it with magnesium ?
I wouldn’t do anything that makes you feel sick. But if your levels drop easily it seems you need the supplement to maintain them which is fairly straightforward.
Does liposomal vitamin D bypass the receptor and enter the cells more readily?
Doubt it.
i have this problem...I'm white and live in Canada
Sadly I have the mutation but taking d
In any form makes
Me feel terrible
You’re not alone. It makes me sick.
@@Silly-Little-Mama your the first one to say the same. Even the smallest amounts make me so ill
Have you ever figured out a solution to vitamin D making you feel terrible? I have the same thing. I've tried so many things to try and tolerate it.
As far as I'm concerned this was click bait. There must be something specific that can be done to activate this gene including diet, supplements and cofactors. This definitely didn't tell me what to do about vdr mutations like the title said. I'm guessing that your a chiropractor???
Mike Morgan lol yes he did. Get those things tested even PTH. And get more vitamin D than average
I think this SNP is still being assessed. In the meantime, use the strategies mentioned in this short video.
I would also add: make sure you have enough magnesium, zinc and vitamin K2 (MK7) so your body effectively utilizes calcium. You don't want all that vitamin D doing stupid stuff.