New Drug Development for Schizophrenia
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- Опубликовано: 24 авг 2024
- This presentation by Oliver Freudenreich, MD, FACLP, Co-Director of the Schizophrenia Clinical and Research Program at Mass General, was part of Schizophrenia Education Day 2018: Progress in Schizophrenia. The Department of Psychiatry provides free educational programs featuring Mass General clinicians for patients and families facing a variety of mental health challenges. Learn more about these programs: www.massgenera...
CBD discussed at 11:00
Exercise discussed at 16:10
Thank you for posting! Thank you for your research Dr Freudenreich
Thank you for this very informative video. I listen to everything I can get my hands on. My 32 year old son was diagnosed about 4 years ago. Long story short, he has just started on invega sustenna. What a difference already. Of course I am concerned about side affects. Will keep listening for more updates in this area of pharmacology and mental illness. Agree something needs to be done to raise awareness.
Medications for the negative symptoms of schizophrenia are needed ASAP
I request all filmmakers to minimize doing horror movies for the sake of these bloody innocent patients...
Yes this mental illness needs more testing,it's a horrible thing for someone to have to live with. My son has this and he is miserable everyday. He will not take those meds,so iam staying here with him because no one else wants to help him deal with his problem. Thank you for caring.
my son is also suffering from schizophrenia . the medical centers put him on injection of Abilify.
he spends a lot of money to the level that I can't cope with it. At times I put tablets of risperidone
with juice or tea I found him did better .But I stopped giving the tablets without his will.
Only thing that helped me was doing walking everday for a few hours and visualising myself burning all the negative images in my mind. I also try to cut out all high glycemic foods and any processed food. Its like i live my life on a tightrope as I refuse medication it is terrible for my body.
Karel zako...I really liked your comment...Can you manage your symtoms without medication?
Do you take medication as well?
Brain damage can occur if you dont take medication for schizophrenia. Then again, long term, brain damage can occur if you do take medication for schizophrenia. It’s a catch-22
@@FromZeroToArtist my guess is that it's all to do with getting the right dosage but the fact that there's an experimental aspect to it is where the danger lays. I found this with taking antidepressants. Several different brands and not one of them worked.
Dr. Freudenreich... Could you do an update with your thoughts on the new drug Lumateperone please?
Thank you very much Dr Freudenreich! I am glad that I ran to this lecture. I used to listen to your lecture of Schizoprenia , in Board preparation :).
Lets treat the person, NOT the disease. Treating the person will eventually treat the disease.
We do NOT treat the disease, we suppress the symptoms, and with that comes a whole lots of other problems. To name few, physical difficulties, diabetes, hypertension, parkinsonism, . A lot more, the list outweighs the benefits.
Let's focus on lifestyle, physical activity, gut bacteria, reduce stress, sleep hygiene, social skills, family support.
NO ILLICIT SUBSTANCES, NO ALCOHOL.
You cant treat someone who thinks his shit dont stink.
We do know schizophrenia typically occurs in teen years, the same time growth spurts happen...so we need research on growth and hormones including vitamin d which acts as a hormone.
If it works everybody would be using it? Well, you could say that about any treatment for schizophrenia. If they all aren’t on the same treatment, we’ll then none of them work, right? I think he’s too pessimistic about alternative treatments. Some of them work for some people. I myself knew 40 years ago that exercise helped my mental health but it was considered an alternative treatment back then or not even a treatment but it worked for me.
Not fair the medicine cost so much
@@HollyWho-sh1dx THIS MEDICINE CONTAIN CBD OIL.....
@@aaymathebest4705 how do you know did you read that book I that guy told you about, do you know the name of the book I'm interested in it
@@aaymathebest4705 I love books 📚
I am on resperidal to treat my schizophrenia negative thoughts and positive thoughts and delusion disorders
I would rather die from medication side effects long term, than live with torturous negative symptoms of schizophrenia short term. Please focus on quality of life as the most important factor. Life is pointless if you cant enjoy it due to apathy & avolition.
Very interesting and enlightening I was basically diagnosed schitzotypal from trauma loss drugs and alcohol do you think SEP-363856 in your estimate would bring a full comeback? Is it similar to intensive aerobic excersise? This is what has been flourishing for me
Schizophrenia is so complex that there is no single solution.
There is a solution. A great book on amazon which will help you greatly, non medication needed, has treatment methods which almost not heard of.
@@htmoh8115 can you tell the book name please?
@@aaymathebest4705 this is a small concise book which you really wouldn't find anywhere else. www.amazon.co.uk/dp/B08MDK65QG
Name of book?
@@htmoh8115Why to write that there is a book, but not to give the name?
CBD should be on clinical trial since it regulates de CNS for people with epilepsy. MDMA in low doses with a clinical setting also should work but this is high on the addictive scale so the answer is only in clinical setting and supervised therapy.
Best way to deal with schizophernia is to show them videos of when they have a relapse. As they deny everything
That seems pretty harsh, a lot of people with schizophrenia can actually recognize that something is wrong after the fact and I can't support taking videos of vulnerable people in that situation. Hope this was a joke...
Is the point to shame & embarrass already suffering people so that you can say “i was right you were wrong”??? What sort of toxic mentality are you on about. The point is to help people with schizophrenia, not exploit them for some strange personal gain. Gross.
The problem with use of anti psychotics is the sufferer forgets everything. So denial is difficult in terms of importance of keeping treatment going. Anti psychotics are hell and suppress all dopamine and motivation. I have my daughter terrified, because for the first time in 8 years, isnt an emotional zombie having been drugged up for 8 years.
She stopped her meds. Now we are looking at adding minerals and vitamins to her epigentics and getting her on low levels of anti psychotics.
There is so much out there on epigenetics especially COMT AND MAOA epigenetics and high dopamine and estrogen issues
We need KartXT for you outsiders it might look as if its working. But its not d2 receptor blocade is bad
What about limbix & luradox medicine for a schizophrenia patient?
I think the sensor system is great. Watsapp being in constant contact with a helper. Mentally ill are isolated and get abandoned by family. Injections are great. Even a brain chip
"Brain chip" Excuse me, what?!?
Having a brain chip is a slippery slope imo. Elon Musk is working on something he calls neuralink which is in similar territory.
I have a question about the drugs, especially Risperdone. If it is prescribed and purchased say at Walmart Pharmacy vs Walgreens, is it different? Are there different manufacturers for the exact same drug? I feel that one of the companies above vs the other works better and the person taking this medicine does not know if it is from either company, they merely have different reactions.
Idk about that drug but I have had different reactions from a generic beta blocker vs a brand name beta blocker even though they were the same supposed formula
Stop taking risoperdone and try zypreza or others…..generic pills are the same as the name brands just cheaper
So cbd oil will work for schizophrenia?
Not for me but idk
@@HollyWho-sh1dx don't give up you are loved you have a gift 🎁 and are talented and wonderful and amazing
If you going to try it do not get sold on gummies or edibles, try the pen and find the best cbd isolate cartrige online. By you saying oil makes me think you have not done your research yet.
Pateints halucinate those horror figures for real......which makes their life a hell on earth............... literally
What medicines that you guys use that actually work?
Olanzapine is good and pretty tolerant.
We need KartXT for you outsiders it might look as if its working. But its not d2 receptor blocade is bad
Can you comment on SEP-363856? (Sunovian)
Does it cure completely...?
Thanks to the other parts of the talk - just please don't make Cannabis into medicines - it causes addiction.
Cannabis contain aprox 400 compounds n only thc is responsible for addiction rest are useful whole Indian Ayurveda depend on hemp as a base . Like alcohol is used as base in allopathy . In aatharveda there r special methods to drive those chemical out using ancient herbs .
The potential for abuse is obviously something to take into account, but they can still be very useful medically. For example most of the medicines for ADHD treatment are narcotic/abusable, but this generally doesn't happen in people that weren't prone to addiction.
Cannabis is way less addictive mentally than these drugs.
@@k10bhandari81 I saw thousands of videos on CBD OIL and English videos on you tube,which people are giving their personal experience on CBD OIL ...CBD IS A NATURAL PLANT AND HAS NO SIDE EFFECTS BUT ANTI PHSYCOTICS HAS LOTS OF SIDE EFFECT
Gan u get a second appion and. Have. They. Got. The right to experiment with people every body symptom is. Diffirent they class u in a geek abuse. U. And twist your. Words and. Think. For. U and treat people. Worst on death row the doctor. Stamp you like a cow we are not all. Dangerous. Don't respect u in. Our. Country. Treat. U. Worse. Than a dog treat people. Are. U. Likely. Be treated.
So while I love natural oil for hair, I think everyone must try Garnier Fructis Sleek and Shine Moroccan Sleek oil on their hair. We purchase ton of shampoos that either work for us or not, so this is a definite treatment of hair follicles and skin. @/differences @/giggles@/scabies... It was basically taking the Blame for the things you have not committed.
What on earth is the connection?