MATERNAL HEALTH 🤱🏻|| Tranexamic Acid (TXA) History

Around 100,000 mothers could be alive if they had access to tranexamic acid (#TXA).
This video is the story of TXA's remarkable inventor, Utako Okamoto, and her journey, fueled by her passion to give back to humanity, whilst ignoring discrimination and sexism in research science's male-dominated culture.
Utako Okamoto (岡本歌子, 1 April 1918 - 21 April 2016) was a Japanese medical doctor working as a medical scientist who discovered Tranexamic Acid (#TXA) in the 1950s in her quest to find a drug that would treat #bleeding after childbirth known as post-partum #haemorrhage or #PPH.
After publishing results in 1962, she became a chair at Kobe Gakuin University, where she worked from 1966 until her retirement in 1990. Okamoto's career was hampered by a very male-dominated environment. During her lifetime she was unable to persuade obstetricians at Kobe to trial the antifibrinolytic agent, which had become a drug on the #WHO list of essential medicines in 2009.
She lived to see the 2010 beginning of the study of tranexamic acid in 20 000 women with post-partum haemorrhage, but died before its completion in 2016 and the publication of tranexamic acids fatality preventing results in 2017, that she had predicted.
The London School of Hygiene and Tropical Medicine Clinical Trials Unit (LSHTM-CTU) has dedicated almost a decade of research around Tranexamic Acid (#TXA) and collated the information in this website (www.txacentral.org) for easy access to researched knowledge for medical practitioners and the interested public.
TXA Central is a resource for health professionals caring for patients with acute severe bleeding. This hub of researched knowledge brings together randomised trial evidence on the effectiveness and safety of TXA.
Where to next:
🚨 For more information on TXA: www.txacentral....
🚨 For more information on the WOMAN Trials: womantrial.lsh...
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About LSHTM-CTU:
Based within The London School of Hygiene and Tropical Medicine, the largest school of public health in Europe, LSHTM-Clinical Trials Unit has a global network of collaborators from over 50 countries with an international reputation for clinical trials, especially in the area of cardiovascular disease, trauma, and emergency care, and maternal health. We value working with patients and the public and they are at the centre of our research activities.
The Clinical Trials Unit (CTU) is a world-renowned centre of excellence in the design, conduct, analysis, and reporting of clinical trials and a fully registered unit with the UK Clinical Research Collaboration (UKCRC). The CTU is based within the Department of Population Health. It has a strong focus on clinical trial methodology, including methods for data monitoring, trial reporting, adaptive designs, non-inferiority trials, surrogate endpoints, the multiplicity of data (eg subgroup analyses, composite endpoints, repeated measures) and methods for systematic reviews, and also conducts qualitative research into the views of trial participants. We bring to these processes extensive knowledge and practical experience of trial coordination, gained from holding a respected position within the clinical scientific community. To date, this has led to successful collaborations in many clinical fields, including cardiology, emergency care, adult and neonatal respiratory failure, liver disease, and reproductive health.
🌎 Follow LSHTM-CTU to keep updated on our research:
→Twitter: @CTU_LSHTM
→Facebook: @CTU.LSHTM
→Website: ctu.lshtm.ac.uk/
#TXACentral #publichealth #medicalprofessionals

[@gnehzeey]

Very remarkable and inspirational! Resources were short in post-WWII Japan, so the wife and husband research team decided to study blood because they could use their own as samples to save on costs. She carried her baby on her back to the lab; she worked long hours; in a male dominated Japan she faced numerous biases and obstacles...
their discovery was neglected for decades; she could never found any local doctors to clinically try her discovery...
As for the cause of purpose of the couple's work, she said＂we wanted to work on something international . We wanted to discover new drugs show our gratitude to humanity.＂What a noble mind!
Her discovery has now found wide usage and is saving countless lives worldwide , esp. mothers giving births. If alive, she and her husband deserve a Nobel.
The world thank you and salute you, lady Utako!

[@youtubereceivesenseIJN]

God bless you even in death, this drug as help me with my heavy painful period and fibroid.
Thank you.

[@zane_sage]

💙💙💙

[@sharikhaifyl965]

omg this is so useful

[@youtubereceivesenseIJN]

God bless u even in death, dis drug is helping in my heavy painful periods with fibroid. Thank you