COVID Mystery - Doctors are Unraveling the Mystery of COVID | Autoimmune Disease
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- Опубликовано: 17 май 2024
- COVID Mystery - Doctors are Unraveling the Mystery of COVID | Autoimmune Disease
There is NEW evidence to suggest that COVID is causing the body to make antibodies that attack itself.
COVID is mysterious in a lot of ways, despite us already knowing a lot about it. Researchers & doctors are working hard to unravel the cause and effect of the interaction between the SARS-CoV-2 virus and the immune system. COVID causes several symptoms that may point to a phenomenon called autoimmunity as a potential cause of long COVID. This includes pulmonary fibrosis, meaning scarring of the lungs. Unfortunately, I’m seeing the same picture unfold in so many of my patients who have had COVID, with all this scarring in their lungs. And COVID can cause other issues, like brain changes, skin rashes, excessive blood clotting, inflamed blood vessels, and more.
Autoimmunity is when the immune system mounts an attack on its own healthy cells and tissues-mistaking them for foreign or virally infected cells. Under normal conditions, the immune system can discriminate between self and foreigners. Meaning it can differentiate between the body’s proteins and foreign antigens. But sometimes, in some people, the immune system can mistakenly identify its own proteins as foreign antigens, and it launches its attack on itself. When these autoantibodies react against self-antigens, the outcome can be inflammation and damage to tissues. This is what happens with autoimmune diseases like Type 1 diabetes, Graves' disease, multiple sclerosis.
This is also what happens with idiopathic pulmonary fibrosis, where people develop scarring in their lungs, much like this happens with COVID. In fact, there are lots of auto-immune conditions that can cause scarring in the lungs, like lupus, rheumatoid arthritis, scleroderma, polymyositis, ankylosing spondylitis, and more-the evidence to support the role of autoantibodies as a cause of more severe COVID. The vast majority of people who get COVID will have a disease isolated to the upper respiratory tract. But in 20 percent of people, the infection will go deep into the lung parenchyma and can cause more severe disease, meaning COVID pneumonia, which sometimes blossoms into ARDS.
Autoimmunity as a potential cause of more severe COVID disease was brought up when autopsies. Cytokine storms are an overreaction by the immune system and are more systemic and short-term. In contrast, autoantibodies are more targeted and long-term. Dexamethasone, a corticosteroid, and the arthritis drugs tocilizumab and sarilumab have been used to modulate an overactive immune response. In a clinical trial, tocilizumab and sarilumab improved critically ill patients' outcomes on ventilators in the intensive care unit.
A study at Rockefeller University in New York enrolled almost a thousand people with severe COVID. About 10% had antibodies that blocked the action of type 1 interferon molecules, a protein that helps the immune system fight pathogens. These autoantibodies were more common in men, who had 12.5% compared to 2.6% in women. This may explain why men are more likely to have severe diseases. Thes are now screening study's researchers 40,000 people to see what proportion of uninfected people carry these antibodies and their distribution by age, ancestry, and gender. This data will be compared to the distribution and percentage of each factor in people with severe COVID.
Researchers in another study supported the finding of increased autoantibodies in COVID patients. The antibodies they found were directed towards B cells, a type of immune cell that produces antibodies and interferon. Although the researchers noted no "COVID specific" autoantibodies that distinguish COVID patients from uninfected controls, the levels of autoantibodies were correlated with known markers for inflammation. The correlations became more extreme as the disease worsened. These medications require careful timing to interrupt an overreactive immune system without interfering with a standard immune system fighting the COVID infection. COVID is often a biphasic illness with an initial phase, primarily respiratory symptoms caused by the virus and the immediate immune response, with innate immunity. Sometimes, it is followed by a secondary inflammatory phase.
There are two immune system arms, the non-specific innate immune system, and the specific adaptive immune system. When infected with a new pathogen to your immune system, you rely on the natural immune system to fight the pathogen. Interferons are essential to the innate response. Interferon-β is one of the first cytokines produced and drives the innate immune response in the lung. This connection illustrates the importance of the finding that SARS-CoV-2 may inhibit interferon activity in those who develop more severe COVID.
Doctor Mike Hansen, MD
Internal Medicine | Pulmonary Disease | Critical Care Medicine
Courses: doctormikehansen.com/courses/
#covid
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They say a little knowledge can be a dangerous thing, and a lot of knowledge can be overwhelming,you’re right there in the middle. Thank you so much for keeping us abreast of this dreadful condition, stay awesome, stay safe we all appreciate you.
Thank you for another interesting video. I recommended your channel to my Doctor friend, who works at a small rural hospital and doesn't feel he is getting enough current, accurate information. He says thank you, too!!
Three things I like about your presentations, Doc: (1) You speak from a position of strength (i.e. knowledge.) (2) You speak in complete sentences. (3) You do not begin half your sentences with that grating, ignorant non-word "UH'hhh," which so many presenters and public speakers must think is the required first word of every sentence. Good Job, Doc... keep up the good work. You are a pleasure to listen to... ☺
Totally agree with you! This Doc is super amazing!
yeah Dr. mike is a true medical rock star.
The power of having Uhhh a script.
SUPER AMAZING AND YOUNG...
CONGRATULATIONS FROM BRAZIL
We, in the US, are blessed to have men who will devote themselves to the advancement of medical knowledge like this man. Indeed, the whole world is blessed to have men like him walk in our midst. Thank you, Dr. Mike ! Blessings upon you.
This channel is one of my favorites! Top-tier content and delivery 👌
I’ll need to rewatch as too much info to absorb for my mindset; however, I do
thank you for the details. 👨🏻⚕️
Just when I think you have hit the last mark you come back with yet more! Thank you!
Thank you for taking your precious time to educate the community. We value your research greatly. God bless you.
Great breakdown of the available literature Dr. Mike!
Good information Dr. Mike. Thanks for continuing to keep us informed.
I think you need a Q & A with someone from the public. During this video you said some things that raised questions in my mind, and I wanted to ask those questions for clarity's sake. Thanks for using your free time to record these videos.
Darius E. Bennett In my opinion i think that's a great idea. Dr. Mike that would help us immensely. Please consider taking questions.
You can email him your questions. I'm sure he will address them in future videos if related to his research/knowledge.
His email address is written in the "about" section of his channel
Media if you want the truth go to net Most Wanted RUclips you need to hit the link below to rumble cuz RUclips won't play the video they censor you the truth you can thank me later
Everyday we learn more and more. Thank you for staying on top of this and keeping us updated.
Thank you . I have autoimmune illnesses and has been asking my docs about this from the beginning. Its relief to have confirmed I'm not as far out as they were expressing then. Thanks for confirming my thoughts
Thanks so much for this information! 💞
Thank you, Dr. Mike, for this video. Really appreciate you. Please get some rest. You look tired. Please take care of yourself. Love you and respect you so much.
Thank you for making this video and filling in some information gaps about the novel coronavirus. I really appreciate your videos and keeping us up to date on current medical information during this pandemic. 💗
Great information ! Fantastic video with images, clips, research papers, truly great. I just got home from working in the COVID ICU and watching this.
Dr Hansen, you have the best visuals. Awesome 👏
Thanks again for explaining what's new. Be safe and stay well!
Not over my head, this is appreciated, thank you Dr. Hansen.
I appreciate the time and care you put into your videos. It's a breath of fresh air to be treated like an adult.
Thank you dr Mike, love and prayers from the Philippines! When things get better,come over,we will show you around
Your videos are always so helpful and timely. Thank you, doctor!
Thank you so much for including us.
Thanks for this comprehensive video. I was waiting for a MD curated info on this topic for a long time.
So glad you are doing this videos! Thank you a lot!
Thanks so much, Doctor. We all appreciate your hard work and clear explanations on all of your videos.
Great job! I subscribed and truly enjoyed your presentation
So timely! Thank you!
Thank you for your amazing work! Promoting awareness, enlightening, presenting in an amazingly well structured and user friendly way complex issues while duly and adequately disposing the scientific sources is of undisclosed value. The contribution made by demystifying, properly explaining health issues, in particular Covid 19 related, appealing to proper conduct and enhancing the role which is being played by both practitioners and researchers throughout the past months is highly appreciated! Thank you and keep the excellent work, our hearts and support are with you!
As always, very much appreciate you videos! Jerry from Spokane
Thank you so much for your help understanding what is known as you know it! A changing landscape in health knowledge. .....
You're one of the few people I've heard talk about undiagnosed things being involved. Bravo :) I've had some suspicions about that sort of thing for a while, cause both diabetes and cancer, and I'm sure a lot of other disorders I don't know about, can be super sneaky. Take care of yerself XOXO
Yep, I have MS and these all sound similar. Thankfully and I thank God everyday that I'm able to get myself fit, strong and healthy. Working on increasing my strength by weight training and eating well to keep my weight down 🙏
Dr. Mike, I comment to help the algorithm. You’re doing a great job.
All I can say is THANK YOU for your videos. I have seen them all. They are excellent !!! (as retired MD, I know)
A great presitation on a complicated subject. I watch all your material.
Much appreciated Dr. Hansen 🇵🇦🇨🇦🧘🏽♀️🙏🏾
Great medical science explained here ! Congratulations!
From my perspective as a rheumatologist, it would be nice to see how many patients with positive antinuclear antibodies in the first study , had ANA before COVID19, knowing that they are present in healthy people also.
I find amazing the idea of comparing the forming of autoantibodies after Influenza infection vs COVID19 patients ! Keep up the great work ! 😊
I agree and I would like to know if these auto ABs are formed after receiving the vaccine as well. We can correlate whether blood types and a parous female change the auto ABs formed.
So much great information. Thank you.
Thank you for a wonderful explanation. This is truly helpful!
Thank you Dr. Mike.🙏🏼
Thank you handsome and macho Doctor ❤️🇨🇦👍. Take care of yourself too and always stay safe🙏
Im subscribing to your channel because you're informative.
Keep it up Doctor!
Thank youuuu
Always great information! Thank you so much! I may have missed it but any information about people like myself that have had a transplant and taking rejection medicines. The recovery from covid-19 or when getting the vaccine?
Pennsylvania appreciates your work, Doc ! Thank you.
dude this guy is a hatchet man of the big pharma, who wants to keep the fear and tragedy of this pandaic alive for whatever reason , that Iam sure you can guess. appreciate him? really cytokine storm has been known since 9 months ago nothing new, yet instead of focusing on immune system regulatory effect of vitamins D3 and C others . he keep on belittling negative effects of drugs and fan in the fire / Iam ashamed of him for not caring for human life
@@jamesprosper4090 he has many times talked about vitamin d and has championed it for use in this pandemic, you must not listen to him often
@@jamesprosper4090 He's doing more to help the population than you are. 🤦♀️🤦♀️
@@itsthespiceoflife he's really not
@@stubadub2k What is your contribution?
I am so glad I found this video. I was diagnosed with an Autoimmune Disease, BUT still have NO IDEA which one I have. I'm also very scared that my poor body won't be able to fight off Covid if I get it. Bevause my Autoimmune Disorder makes me not able to walk, I feel it attack my muscles. Thankyou very much for this video.
Completely change your diet. Go organic, reduce stress, boost Omega 3.
You need to find out what u have!
Goodmorning and win Today. Thank you Dr. for the information. Appreciated
Nice presentation - you are more relaxed. Great job.
My Husband and I had Covid. He is 80 years old, I am 63. We managed it at home, feeling quite ill for about 2 weeks. It took another week to get back to normal. We feel *better* than we did before getting Covid. It strengthened us somehow.
Hope you have fully recovered. Just wondering do you and your husband get the annual flu vaccine ??
Highly suspicious of this comment. You have 17k subscribers?
Excellent presentation. Thx so much!💖
Hi DR.HANSEN ✋ THANKS FOR ALL YOUR INFORMATION. YOU ARE AWSOME AND THE BEST. THANKS PAL HAVE A GOOD WEEKEND!!! ✌👌 👍
Thank you for all your videos! Ive been learning so much i feel like a pro now haha. Lots of love and take care of yourself doc! X
Very well explained, as always.
Thank you so much for this most interesting video 😊
Very well done, the graphics and images help so much
I know there are enough comments here stating they got the main point of the video, but not the details. I hope you continue to speak at this level for those of us who can keep up with the detail but don’t have access to the research. Thank you 🙏! I actually do have notifications turned on for your videos.
Wow, tons of detail, I felt like I was back in university.
Thank you for making your explanations understandable. Both my sister and I have autoimmune diseases and both of us have had Covid-19 so we are very interested in this topic.
Hello, I know it has been a year since your comment, but I just wanted to know how you and your sister are going on this matter... I have had Covid 6 moths ago and recently my doctor told me about some antibodies in my blood. I still have some pain chest (not alway) and 1 month ago, I started to have some pain in my left hand, specially when I'm sleeping.
Did you get better? What treatment did you have?
Appreciate your help.
Thank you and God bless. I am sharing this info with everyone that I know.
i keep watching and been a long time subscriber to you Doc with all of my yt accounts.. its mornight 1a.m now all the way from here im your fan from The Philippines.. 💕💕 take good care Doc. Mike and stay safe always and keep dedicated to your good intentions.. 💖💖
Thank you, doctor. Your dedication to sharing your knowledge is appreciated.
When I got sick last Feb, a symptom I felt that hasn't been mentioned was the feeling of tingling jolts in the face; from forehead down to around the eyes & cheeks. Also, one of my first symptoms was jaw pain.
That’s most likely anxiety I’ve felt it before and trust me it’s scary when it happens u just have to try and breathe in and out to calm down you prob were really anxious and stressed knowing that u had it wit good reason
Sounds similar to what my daughter told me when she had covid, she said she felt periodic zapping/tingling feeling throughout her head, almost like small jolts of electricity
Mine was a horrible headache with disorienting dizziness
Solis, Carmen calls this "anxiety". Not. This is identical description to flashes or jolts I got along facial nerve after prolonged vertigo episodes over the course of a year. This was finally realized by me, due to other incidents and symptoms, to relate to the migration of a herpes infection migrating through the nervous system. I'm thinking A. the Covid, if that was your "sickness", also migrates through the nerves or B. you had herpes and the Covid reduced your resistance and the HSV advanced in opportunistic manner. Covid-19 targets the hypothalamus in the brain.
COVID affects a multiplicity of body parts, and the fact that it often kills the sense of smell indicates that it is affecting the brain. So I'm going to make an educated guess that it was affecting your nervous system. If your glands were swollen and your nerves were affected, the jaw pain is not surprising.
Excellent video with great explanations in such a short time.
This seems to be objective and informative. Great presentation.
Thank you (again :) ) Dr. Hansen for the scientific update in a field of knowledge with such political and social turbulence. It is people like you that have given people like me comfort through these unique times.
Beloved, I don't know you in person but God know you. God ministered to me in a revelation when I was on your profile to see things around you,I saw blessings but spiritual attacks holding onto them,in prayers,i saw a woman in the realm of the spirit monitoring and plotting delay in your life, with an evil mirror, and with motive to destroy. But as I speak to you now her time is up, Render hand of favour with Anything you can afford or give to these motherless foundation (Twins Alive Foundation) in Edo state Nigeria before Two days with faith, as I Rise my hands towards heaven and pray for you they shall serve as point of contact wherever you are, you will receive double portion of grace to excel and total restoration of breakthrough in your life and in the life of your family. Ask for their acct details and help them call the MD in charge of the orphanage to get their details on (WhatsApp or call them now on +2349150335948) tell him I sent you. For it is not by might nor by in power but of the spirit saith the lord (zechariah 4:6). You shall testify to the Glory of God in your life. God bless you in Jesus name
Am in SA/🇿🇦 and I appreciative of your educational work
Compatriot, I agree.
Another comprehensive and educational video. Thank you, Doctor.
I am really very thankful for ur informative knowledge n appreciate the way u explain ....this means a lot for me n I pretty much relieved n somehow happy after listening u ...thankful to u ...keep going
thanks, Doc. Hope you stay healthy and thanks to all the doctors, health care workers, scientists studying this, CDC etc who are on the frontlines trying to help us all.
So informative and interesting. Thanks.
Sounded like a load of BS
Wow. Thank you for this information. I had the virus in April, and it had made my asthma worse at that time. It took me a long time to get over this evil virus.
Fascinatingly thorough. 🙏
Somebody tell Violin MD about this. She's training to be a rheumatologist.
Oh, I love her videos!!
She knows.
I would be interested to see the outcome of a person, who is actively being treated for Multiple Sclerosis with the common medication, but has also contracted the CoVid-19 virus. My question being: would the medication being used to treat the MS help buffer the immune system's attack against the body's organs due to the CoVid-19?
Oh good idea. That would be interesting!
People with an immune modulating medication maybe, but not those with an immunsuppressive one.
I've been very interested in that too. I believe it would. It would depend on the level of treatment needed to control the MS - ie.. can you still fight off colds and flu's normally? If so, you should still get an immune response to the virus, while also preventing the cytokine storm that does the real damage.
I'm currently dealing with an unknown autoimmune disease on top of Fibromyalgia. It's most likely Lupus. If I get Covid, I fully intend to take a low-dose (40mg) of IM Depo-Medrol steroids immediately.
Edit: I actually got sick earlier this year with lung inflammation and other Covid symptoms. I had to wait a week for a test, and I took the Medrol then too. Turns out, I didn't have Covid.. but I did notice a huge difference in my lungs. Between that and inhaler steroids, I was able to fight it off. I get chronic pneumonia, so I'm very familiar with those symptoms and progression. Honestly, the Medrol surprised me in just how effective it was in stopping that infection.
What about people who have ms but do not take ms drugs and instead take high doses of vitamin d ...like me. Will we automatically go into overdrive cytokine mode?
I know two people with medication controlled MS who think MS has gotten better after complete vaccination.
Very good presentations,thank you Dr.Mike Hansen.
I love your videos. Very informative. Thank you!
Good info just a bit over my head.
You can really googled much of this information and seems to be straight forward. It’s really cool info. Love this channel.
Listen more than once, Google some of the words, it will start to make more sense. This info is so useful...
So don't get brain dope, got it. May the anxiety, ptsd, and depression not hurt my heart beat
Thank you Lord for doctors like Mike Hansen, for the knowledge and genuine interest in informing us for best of our Health. We love you doctor. 👏🏼😊☺️🙏🏼
I agree. All doctors should explain what is going on with any illness but they don’t think we can understand.
Amen
A doctor that is humble is not common and that is why I support u.
Thank you Dr. Hansen. Great video.
Thanks Mike, I heard that some people on auto-immune medication could be at a lower risk of catching Covid-19. It was reported here in the UK that steroids like prednisolone could be a good treatment for people who are intubated. I take prednisolone for my Mysthenia Gravis but would it be a risk-reducer?
Dr. Hansen, I have scleroderma with anti centromere antibodies. I was trying to find studies about the safety of the COVID vaccines in people with autoimmune conditions and I have not found any. Could you please shed some light on it?
The symptoms and complications from COVID seem to be very similar to that of CREST Scleroderma.
Thank you SO MUCH for this most insetting Analysis. Amen.
I survived covid pneumonia recently and still doing budesonide inhalation treatments every other day a month later to help with lung fatigue and coughing. I’m waiting to get into a local study at UTSW here in Dallas for post covid patients. This info is great that you’re posting. I’d rather know what I’m possibly dealing with than ignore it. I also received a dexamethasone shot and was able to avoid hospitalization.
My father (72) had the same. He has an asthma spray to help as he gets fatigued just with walking short distances. His a type 1 diabetic, heart issues and had water in lungs while fighting Covid/pneumonia, low white blood cells platelets and had oxygen therapy plus walking therapy.
I beat the coronapocolypse by doubling my vitamin intake especially D3,K2, zinc, The food we eat today doesn’t have the vitamin and mineral content it had 75 years sgo
I have friends and neighbors that did the same thing including nebulizing peroxide.
You definitely want to do the best you can for your health by taking certain supplements for sure. Most health professionals who died had been working double shifts for days. Fatigue kills the immune system.
Great video! Is there are study on COVID effect on immunodeficient patient. What kind of virus it is and if cytokine storm is not present how much damage the virus itself (not the immune response) actually does? If the damage is not extensive, it might be worth to suppress innate response until the adaptive response kicks in, even when that would produce temporary larger in-body viral spread.
Your videos are very informative! Thank you soo much! I have an Autoimmune Disease, this inflammation is very important to me. 💘
Love your content...and your smile Dr Mike.
Always non-political! Thank you!
Thanks Dr Hansen for keeping us updated on everything and following up on the case from Miami . Praying for everyone to make the right choice for them with this vaccine . God bless you stay safe. Thanks for all that you do 💖🙏🌹🌹✌️
Yes, he is so clear,to explain. What is Brain Fog ? Can you explain, CONGRATULATIONS, MIAMI, USA, superbowl,
Thanks for sharing.
Dr. Hussain
Excellent in depth objective research and balanced commentary!
Would you suggest getting the 2nd dose of the vaccine? Thank you for your response.
Thanks for another great presentation. Any thoughts on the new Covid drug from Israel given via inhalation Qday X 5 days? Thanks!
I had a "mild" overnight hospitalization a few months ago with Covid. After watching a this video, I believe I dodged a bullet and I was a day or two away from being in some serious trouble if I didn't go the hospital. My perspective on life has changed after my first major medical scare.
@illuminOz dude you’re a conspiracy theorist on RUclips. Chill out, you’re getting so riled up over someone else’s experience.
This is very educational for me Thanks Doc
What were the recent investigation results regarding blood group susceptibility. Rhesus +ve versus -ve with O versus AB?? There has been an unnerving reluctance to release the findings.
If you have type A blood like me, take no chances.
I don't see it makes a difference. I have type O but still don't want to be exposed.
Blood type has nothing to do with it.
They recommend patients wait 90 days post Covid infection to get vaccinated. Are you seeing any reinfection or worsening outcomes with in patients?
Another superb video I'll need to watch a few times to fully understand