Matthew Perry FULL Autopsy Report - Doctor Mike Unravels Ketamine's Role
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- Опубликовано: 26 сен 2024
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“Friends” star Matthew Perry died as a result of “acute effects of ketamine” and subsequent drowning, an autopsy report shows.
The report, released Friday by the Los Angeles Medical Examiner’s Office, shows Perry’s blood tested positive for ketamine, which is known to treat depression and anxiety.
“At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression,” the report states. The death was ruled an accident, according to the report.
Perry was found floating face down in the pool of his Pacific Palisades home on October 28. Authorities said at the time that no foul play was involved.
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In my 21 years of critical care nursing, I have NEVER heard of an anesthesiologist functioning as an internist. Matthew Perry wasn’t at home intubated, ventilated, and monitored.Sounds super sus. And in Michael Jackson’s case, never trust a cardiologist with Propofol. These boutique, celebrity docs need to stay in their lanes.
My GP used to be a surgeon.
Can I trust him? 😅
@@MrNicoJac🤷♀️
He could easily have gotten it on the black market.
@@infinitemonkey917 Yes. I am just speaking of a certain set of providers that end up in the yes-people category that provide certain benefits others in their professions would not.
Agreed
Yellowing in right pointer finger. Lol our boy here is perplexed about this,yet he's talking about all the effects of smoking on the lungs.Ahem.
*Tobacco stains😂*
I pushed the like button with my nic finger 😂
My guy, you are a genius. Well-played.
Haha I agree, he was showing his younger age.
Such heartbreaking news about Matthew Perry's passing. 💔 The revelation of the autopsy report is truly saddening. Mental health struggles are complex, and it's a reminder to approach them with compassion. May he rest in peace, and may this encourage open conversations about mental well-being. 🕊❤
It is sad but also he got his wish. He wanted to be remembered for helping other folks in addiction. Ketamine has been known to trigger relapse and perhaps should not be used in those with substance abuse. It is tragic to all of us struggling but the work continues. May he rest easy now and his loved ones begin to properly grieve and heal.
So much for HIPPA.
I've been watching since Covid and I'm so happy to see your channel grow. Your medical knowledge is invaluable. Thank you for all you do to keep us informed and healthy!
Thank you for explaining this. It is so so sad. It seems he suffered many ways during his lifetime. We will all miss seeing him act in the future. May he live on in memory of how he made us all laugh. God Bless Mathew
Absolutely, it's heart-wrenching to learn about the struggles he faced. Matthew Perry brought so much joy and laughter into our lives through his acting. May he be remembered for the smiles he brought us🌹💙
Thanks for breaking down his Autopsy Report Sad he had to pass away ... he was a talent actor, funny, and will be greatly missed. R.I.P Matthew Perry
Thank you for the info. Sadly with all of his health issues it makes you wonder how much longer he would have lived had he not died in October. My Father died of coronary artery disease and my mom was diabetic. Serious illnesses. Cannot imagine if they would have had all of Matthew's health issues. May he rest in peace.
My guardian angels were my dogs. They could warn me 30 minutes before an episode set in. They would annoy the hell out of me till I acted right. Saved my life. Dogs, must have all kinds. At least one large one to literally pull you out, in case of an accident.
My sisters dog 🐶 would not go near my Nan as she had cancer and every time he would see her he went crazy barking! We guess he could smell the cancer ! Yet her other dog never barked so maybe certain dogs would have the gift
Wth? Better not to do drugs than rely on a dog to sabe you. No offense but offense lol
@@carolinekelly8481There are certain dogs that can diagnose/sniff cancer and other stuff
@@mareezyin matthews case, quitting drug was very difficult. he’d been doing them since he was 15-16.
@audrina_db yeah, so sad. I think he was drinking since 13 or smt. So sad. I wonder if he had bad parenting.
Its disgusting to me that autopsy reports are public record in America. This is extremely private medical information and the patient and family have not consented to this. It feels extremely icky and invasive and violating
An autopsy report is NOT public record. It will only be released to the Legal Next of Kin(LNOK) and the investigating agency (usually the police) of the jurisdiction where the death occurred.
Love your video's Dr. Mike. Very very educational.... Including this one dealing with Perry. Thank you for sharing.
Thanks for the excellent analysis. I was never a fan of Matthew (I am too old)!but I think his death was quite sad. I listened to a large section of his book and found it incredibly sad. May he rest in peace.
Why are people's autopsy's 'public record'??
Shouldn't this stuff be private???
Yeah. My mind is blown! How sick!
Like Wills there are certain documents that are in the "public" domain. You can get anyone's autopsy or Will such as Princess Diana, JFK to name a few.
Privacy, huh, a dead person?
Very helpful to have a qualified professional's review. Thank you.
I just finished ready his biography. He was so hopeful at the end of the book. And he was so loved by others. So sad. An aside, yellowing of index finger nail- nicotine?
It's sad to know that he's not here anymore. Rest in Peace to him and my condolences to whole Family.
Thank you. Dr. for explaining all the issues and drugs that he had in his system.Unfortunately that added to his passing very sad so young!!
Fascinating. Amazing that RUclips enables this kind of detailed well-supported analysis and insight vs mainstream undignified uninformative drama blobs! 🙏
I just listened to his book a few days ago, narrated by him. His alcohol & drug intake was tremendous, for years. At one point he was taking 55 vicodin a day!! The last chapter was so sad, he was so hopeful for the future but it was as if he wrote his own eulogy. Rip Mathew.
After so many reviews, I'm going to get the book. Sad to admit, I haven't read a book in years (podcast person). But I look forward to this one.
55 is ridiculous and he was on much stronger drugs as well as vicodin (xanx, oxy etc) as well as alcohol. He is so lucky he lived past 27 to be honest.
@@LazySusan.same here
Thank you for explaining that. Just having done that in a pool instead of in bed, made all the difference. We will all miss Matthew Perry.. at least, I will.
Right... but I think on this course it was all a matter of time.
I think he sent his assistant away so he could end his pain....
I am starting to think the same. 😢
Thanks for the info. Having an anesthesiologist as your primary care doc is a huge red flag. If he had been in recovery for over a year and a half he should not have been on the combination of meds he was on, including the lorazepam. He should not have had ketamine in his system at all because of the short half-life. He was still using….God rest his soul.
My GP used to be a surgeon.
He preferred working with people instead of on them, he said.
It could well be that his primary care physician preferred interacting with his patients while they were conscious, after a few years.
The proportion of physicians facing a claim each year ranged from 19.1% in neurosurgery, 18.9% in thoracic-cardiovascular surgery, and 15.3% in general surgery to 5.2% in family medicine, 3.1% in pediatrics, and 2.6% in psychiatry.
Always good Dr. Mike. This man was really F’d up. Forget the ketamine. NUMEROUS underlying conditions.
Ketamine is not FDA approved for depression. Esketamine is. But only under a strict REMS program in which patients are monitored in the psychiatrist’s office during administration and for 2 hours after. Anesthesiologists are not trained to treat depression. There should be a malpractice lawsuit to set precedence.
Off label use of ketamine is commonplace, even published in studies.
@@jamesgerboc so was lobotomy; commonplace and published in studies!! That didn’t make it any less harmful!! I’m a psychiatrist who treats treatment resistant depression every weekday. I make frequent recommendations for ECT, TMS and Esketamine (under REMS) but never for home administered ketamine. If I get called as an expert witness on a negative outcome of home ketamine administration, I will call it out of the standards of practice. Period!
Between the type 2 DM, COPD, & CAD, we can see how hard living when you're a young adult really contributes to irreversible disease processes later on in life. I heard that young adults aren't drinking as much as my generation and that's wonderful. I hope it's true. I hope this generation learns from my generation how abusing alcohol and drugs will lead to an early death or worse, a disabled middle aged person which usually leads to depression, chronic pain, self medicating with drugs and alcohol. It's a viscous cycle. I worked in an Amarillo, Texas hospital during the pandemic and was shocked to see how many men in their late 30 & 40's getting their toes and feet amputated from primarily two 2 diabetes. These were hard working Texas guys. God bless them. I wish I had the answers.
Many of these conditions are reversible by taking massive action and making lifestyle and nutrition changes. The body has an incredible capacity for healing. ;0)
@@WH2012 I agree! I also wanted to make the point that the next generation is recognizing the damage drinking alcohol in excess or anything in excess is hard on the body. I read a study that said if you have been physically fit one time as an adult, your risks for CAD & cardiac events is greatly reduced.
@@mycatsnameiskaren8253 Bingo! 🎯
You explained everything very well. I found other news reports explaining the cause of Mathew's death a bit confusing. His death is so sad.
He worked very hard to kill himself. Not an accident.
Just listed to his book so incredibly sad
Thank you for your very informative explanation.
Are all people's autopsy reports public record if you die in the US? seems like a very personal document that I wouldn't want shared publicly...so I'm just curious.
Sorry but smoking and patients with emphysema do have clubbing of the nail beds clubbing is also caused by issues with oxygen levels.
It seems to me Matthew Perry got "special" care. Dr. Drew Pinsky has spoken out against that kind of stuff. In any case, may Matthew Perry rest in peace.
At his book discussions (Toronto) he said he wrote the book and was talking about his addiction to help others. The best thing he would want, I think for all those who mourn him now, would be for those who followed his career and enjoyed his entertaining………to help addicts to stop. Addiction as he said is cumulative and unless people get help and stop, they will eventually die from the disease- prematurely or from complications. He knew this. He did not want to die, but made some mistakes because he did not stop. Just help others to get help and stop. Save a life.
I've learned over the decades that you can't help an addict stop using, only let them know you are there for them when they are ready for help. Sadly, often, they only need you to help them attain the substance, i.e., give/loan money. It's a difficult thing for anyone whose friend or loved one won't or can't get the help they so desperately need.
@@Julia-uh4li agree with you!! They have to decide for him or herself to stop. IMO, Matthew Perry’s success with Friends hurt him. The money he had insulated and enabled him to keep using. At some level he did not want sobriety enough to stop. Reading his story- there are many symbols of arrested development in his personality …..he was unwell, internally he destroyed his body, it’s amazing he did not develop any number of cancers from pancreatic to hepatic. On the good side- there are lessons to be learned from him and that is what he wanted for all those taking drugs or alcoholics. That is a blessing. Learn from someone else’s mistakes.
Hello, doctor. Can you make a video about the meaning of "natural death" relating to the death of Sinéad O'Connor?
Hmmm, will there be an investigation into how he got the ketamine? I agree with you about his PCP being an anesthesiologist. This is reminiscent of what happened to Prince. So many influencers are talking about going out of the country for ketamine therapy. You should do a video about the dangers of this therapy. His autopsy read like that of someone 20-30 years older. ☹ I hope he didn't suffer. RIP.
man this guy was literally walking dead.
That's what 34 years of alcoholism, smoking and drug addiction will do to a body.
@@Peanutdenver Don't forget the pickleball! 😉
He sure was! I'm surprised he was able to play pickleball! ;)
@@bobjohnson205 Pickleball is the number 1 cause of death when playing on the train tracks.
This is fascinating! Thank you for doing this. I've been a nurse practitioner for 20 years and now reside in Florida and work in a private clinic but my experience is in trauma/ER. I was in nursing school when Friends started so needless to say, I'm a huge fan.
Why would a doctor prescribe Ketamine in a dose sufficient to cause this kind of event, especially for someone with a history of substance abuse? Why would Perry have needed a constant supply of the drug? What benefit would that have caused?
I don’t think he got what he used that day from a physician, could be wrong.
I agree.. It doesn't make sense
My question exactly. I don't think we are getting the truth of what really happened.
@summersalix, Like Judge Judy, says, " If it doesn't make sense, it's not true". I agree with you this makes no sense at all.
The infusions are performed in a doctor’s office and the patient is supervised for a good length of time afterward.
Oooooo, Doc I have CAD/CABG/1 year later 1 failed artery bypass. Very interesting to hear your commentary of the report. Thank you very much. 😊
Hi Dr Mike! Great report. I was wondering if that discolouration of the index finger/finger nail was from all of that smoking? Unless I misunderstood, that was the very first thing that came to mind. I’ve seen lots of badly discoloured index fingers on heavy smokers. Thanks again for your great report. May MP RIP.
Remember he also had one finger joint cut off early in life. Compensating or angling of the cigarette over time?
You could see the discoloration on his finger from smoking already years back. I was a former smoker as well, and it took years for that yellow tarring to go away. He had been a heavy smoker so that was not surprising.
A relapse, seemingly aided by a medical doctor. Addiction is rough! It's exhausting. I have 2nd-hand (1st hand?) experience as an AL-ANON (former spouse and also multiple family members). I hope he somehow found peace.
Thank you for this information on the autopsy report. 👍 18:03
Very interesting Primary Care Giver!! Sad. Perhaps his primary care doc would like to explain.
Good information!Thank❤ you for sharing
Dr. Mike - great to hear you doing this video. I knew it would be good when I saw your name.
Sorry, but how does one get to adulthood without the clear understanding that drugs, being alone, and any body of water, do not mix? Potentially lethal combination for any one of us. Sad mistake.
RIP Matthew. 😢❤
How do we ever understand the way an addicts brain works I guess. I don’t think they understand themselves as they live in a world of deceit and pain. It’s so terribly sad.
same way people know what they should be eating and doing and yet end up unhealthy. it’s easier said than done. EVERYONE knows what’s good for them. doesn’t mean they are always able to follow those behaviors or avoid unhealthy behaviors. it is sad. :(
He has probably done this mixture along with hot tube many times without issue..making him feel safe
@@kenziedicken9512This is a FANTASTIC example. Thank you
@@Jeremya74Probably. I'm guessing that post on Instagram was an example of this. Which explains some of the nonsensical language as well ppl are trying to make into conspiracies.
Geez! This guy was in bad shape. I'm surprised he was able to play pickleball! That game's a real killer! lol
What 😮
I cried reading this. Such a tragic accident .
Thank you for this post!
Dr.Mike, I’m a retired LEO. I’ve witnessed Ketamine being used by medics in the field to treat excited delirium. You have any opinion or knowledge of this treatment? Thanks.
Dr Mike, as a smoker Matthew Perry's right index finger very likely stained 5:41 from nicotine use over decades. It's where he held the burning cigarette.
The pharmaceuticals companies start here. Slow and steady. And end up starting a nation wide opioid epidemic.
Thank you❤❤ RIP Matthew
Isn't ketamine used in the acute setting for blood pressure? Has no one investigated a.possible link between severe hypotension and very hot spa water? Generally, hot rubs are not recommended in combination with anything that involves blood pressure because of the risk of cardiac arrest I thought. Would his doctors not have advised him to stay out of the hot tub? What a shame.
Hot Tubs are a danger, in general. People love to sit in them when under the influence of anything which is exactly what should not be done.
An anaesthetist (as we call them in Australia) practising as a GP is bizarre. I wonder if there's more to come out here.
That is weird. Anesthesiologist are not primary care doctors. Sounds fishy.
Thanks, great explanation!
Would the lack of water in the lungs be because of COPD? If he drowned wouldn't their be water in the lungs? The absence of water has left me with more questions than answers.
I’ve been wondering the same thing since I read the report, but no one has addressed that. How does one drown if there’s no water in the lungs? This detailed explanation makes me think it wasn’t drowning, but rather the respiratory suppression that caused his death. All the meds that depress breathing combined, so when he passed out he stopped breathing. Makes more sense.
He was taking anesthesia levels of ketamines.... which also suppress breathing.....
In a hospital setting, you'd have a breathing tube + a machine breathing for you..
@AhhhSukeSuke love your name btw lol
@@AhhhSukeSuke I'm thinking given not taking
Great video. Three different respiratory suppressors on board and then getting in a pool sounds potentially deliberate.
Sounds like he was getting ketamine on the street. While it’s not a suicide, he basically did kill himself. Shows how deadly addiction is. He was looking for a way to get high even tho he was “sober”.
Maybe his anesthesiologist primary physician is a close friend. Like he said, it's unusual for an anesthesiologist to be your primary.....
Listen a few more times
Has anyone wondered why someone regularly taking ketamine infusions in a doctoral office, who therefore knows the effects or the drug even under supervision, chose to take it in the pool? I feel sad for his friends and family
Essentially Death caused complications by drugs with deterioration of health. Ketamine therapy can still be extremely dangerous depending on their health, this is a perfect example as to why. Whilst he was off the "old drugs of choice" he was still on drugs, he was just sober by the societal norm, but the medications themselves are all addictive in nature so it was switching one set of addictions to another, that were in this instance, lethal in the manner in which they were taken.
Rest In Paradise Matty 🙏🏽🕊🥀
The guy was on death's door from the beginning, I'm so confused how they are attributing the death to ketamine when you are stating had he not been in the pool he wouldn't have died. That's like saying a person died from alcoholism when they ram their car into a wall at 80 mph while drunk. JMHO
So sad as on Christmas eve last year my mildly mentally deficient sister who lived in Ireland in an amazing community with people with similar problems. She married a man with similar problems and they both worked 4 days a week and had carers who kept them in check. So sadly she died of pulmonary embolism due to flight. All I am trying to say is my sister had a genetic anomaly and died and as much as I love Mathew we need to create a base of care. My sisters community helped her but the rich turn to drugs, I also have problem on a lower dose but every day is a fight, which I do not understand as I am a well educated and "normal" person but for no reason I understand addiction kicks in. I was 35!!
Yellowing of an isolated nail could be from smoking cigarettes and affected by how he held his cigarette.
I hope everything is going great !❤stay well always -missing you!
I hope his family sues the doctor who prescribed all that 💩 to Matty 😑
He did IV Ketamine therapy 2 weeks ago, but he had ketamine in his system - ketamine stops being detecteble after 4 hours after being used. I suspect he was given take home ketamine tablets, and him being an addict - and ketamine is ofter abused, I suspect he relapese.
Thank you….
His primary care doctor being an anesthesiologist makes perfect sense, since there's hardly a better specialist to manage opioid addiction. I don't believe at all that he got the medication from his attending physician. It's a known street drug that he could easily get access to since he was very much used to seeking drug dealers. Also, there was no signs of needle punctions on his skin on the autopsy report. No drug paraphernalia found (to turn liquid into powder, for example). He probably bought a gram of powder from a dealer and snorted it all (maybe he thought the initial effect was unsatisfactory since the onset is delayed if given IN instead of IV). Bioavailability of intransal route is approximately 50%, so 500 mg for his size and weight generates the 3.000 ng/ml found on the exam. Makes sense. He probably dissociated very hard and went face down into the water, drowning being probably the primary mechanism of death.
He sent his assistant on an errand. Anyone who is rich and has a drug courier come to his/her house knows what that means. But he says Special K was not the drug for him, in his autobiography. He must have really been desperate to take something for his depression that he thought was okay.
What he really needed was a reset -- brain chemistry at factory settings.
I am so sorry he didn't get to live to be 80 and tell people he had the greatest life. Chuck Negron's autobiography, "Three Dog Nightmare," is a story like that.
I am going to look for some more of these stories because Nikki Sixx's autobiography is also incredible. If you woke up and your house was a Beverly Hills mansion, why would you spend all your time sitting on the hard wooden floor of a walk-in closet on the third floor and keep calling the security service, "There are little men in trees with Uzis pointed at my house."
yellowing of the nail might be from smoking cigarettes
I read the autopsy. Sloppy work. There is a lot of missing information here by the coroner.
And, it’s being given for pain. As in the Maya Kowalski case
Interesting, no cirrhosis of the liver. Although he battled alcoholism most of his adult life. RIP.
People's bodies vary a ton when it comes to getting that from severe alcoholism. Some people get it in a year or two of heavy drinking and some never get it through a life of drinking. His body was pretty messed up though even if he didn't have that.
One nail is yellow from smoking OBVIOUSLY.
One yellow fingernail and that’s all? The autopsy didn’t mention that (I think) he lost a middle finger years ago, so his doesn’t have a nail on the next finger.
Was ketamine from a medical doctor, his anesthesiologist? Or off the street? It IS a controlled substance, right?
And on top of that: why have an anesthesiologist as your PCP? Primary Care Physician?
Doctors taking advantage of him- same story as Michael Jackson.
So sad!
They both just needed a massage with relaxing aromatherapy before bedtime-- and some relaxing guided meditation to sleep with natural sleep sounds …
May Matthew Perry Rest In Peace.
His nail might be yellow from nicotine staining. No reason to assume he stopped smoking.
On the last day of his life, someone snapped a photo of him smoking.
Please read (or listen on Audible as I did) his autobiography. His bowel exploded and he nearly died..... multiple times. His body was wrecked...bless him.
Never been so saddened at a death of a celebrity.
I think Matthew did the best he could to live his life and stay alive as long as he did.
There were few times he wasn’t suffering
Yellow finger, nicotine stain....?
That is so heart breaking😢😢😢😢😢😢😢😢😢😢 no words left😢😢😢😢😢😢😢😢😢 I'm just so sad he is gone😢 a the readon is even more heart breaking. So sad😢
hmmm will they be looking at this anesthesiologist in his death I wonder.
Any thoughts on his hands??? They’ve been that way for a while now. His turned down nails… they cupped the tips of his fingers.
You need to remove the Close caption embedded in the video. Annoying as all heck. Couldn't watch or see half the screen.
agreed, I literally just listened versus looking at the screen. RUclips gives us the CHOICE to use closed captioning in Settings.. I dont understand why content creators feel the need the use it, hes definitely not the only one. and YES ANNOYING AND DISTRACTING and unnecessary.
not only annoying but also, in many instances, incorrect transcription of what was being said
I think that was purposeful so you’d have to watch the whole video instead of just reading the document through, I was trying to read it as well, I agree extremely irritating.
Which nail bed was yellow ??? Smoking?
This is so sad.
Having suffered from severe depression, I had always thought of asking my Dr about and/or for Ketamine. Name brand Zoloft did wonders - not the generic! Personally, generic Zoloft, Sertraline, is terrible. After listening to this, the interest in Ketamine is gone. If necessary, Zoloft is my best choice. Ativan is something i take but not every day, not every week. I wouldn't doubt he was taking 2 mgs which is the highest level. 1 mg does me fine because the more you take the higher tolerance the body has for it. He's got a good mix of drugs that don't work well together. As an ex heroin addict for thirty years, I am very careful of what I injest especially at the age of 67.
It sounds like he was not the healthiest of guys and didn't have the best of medical advisors. People, do your research. It's not difficult!
Same with depression and also ptsd. I am also very interested in the treatments, it really sounds promising from what I've seen. I drink a tea for all my issues. Nothing pharma ever helped me long term.
Diabetic.. heart etc...
he more than likely self medicated himself , a drug seeker and had more than one doctor.Someone with his history should of been flagged an not prescribed these drugs, ketamine for at home use in pill form for a person with his past should of been used as last line. Instead CBT, TMS,ECT, whole health, Mental Health program with a LCSW and a psychatrist routinely. A good PHP program. Perhaps it was intentional on his part.
Dr Hansen, could you go over Mast Cell Activation ? Thanks.
It's mind bogling to me when people like him and Steve Jobs have astronomical net worths and can afford the best health care on the planet and they choose to self medicate. Had perry truly looked for help he would still be here today. I know because my father overdosed 6 years ago as well. And he gave up on himself. It's when you stop fighting is when you get consumed. Rest easy.
He was a walking time bomb. If this didn't kill him he wouldn't of lived a long life.
He was known to have horrible bowel scarring from opiate induced infarct in his bowel. He had a colostomy for many months.
Anyone know why the chemical associated with Klonopin was in his system? Just curious. Im also confused about why the effects of Buprenorphine AND Ativan weren't mentioned as contributing medications. Both cause respiratory depression. It almost makes it seem like Buprenorphine is something that's more dangerous. When Subutex and Suboxone can be life changing for opiate addiction. Anyone who can answer these questions much appreciated.
Hey doc can you help me please? Why do I feel sick when after I eat
Who prescribed thesee meds witjout telling him not to mix the 2?
So, accidental drowning with underlying health issues?
YOU AREN'T SUPPOSED TO SMOKE ON Brupopian (Wellbutrin)
If I heard it correctly, I'm not a native speaker, the yellow fingertip in just one finger, the index, is due to holding the cigarette in heavy smokers. It's usually the index, can't figure out why, since a cig is held with 2 fingers.
Hey live fast die hard.. he was a very wealthy man he indulged in that and it ended up killing him.. all these were choices that he made.. he doomed himself
😮❤ So where did the extra Ketamine come from? The street? A dr? wow these celebrity doctors shock me as a RN 4 39yrs 😢