Mechanism of ATP/ADP Cycle

The ATP cycle is actually is a set of two biochemical reactions that occur in a cyclic manner.The endothermic and exothermic reaction takes place in this cycle.
In this part of Video ATP cycle has been discussed in detail.
and in next part ATP molecule has been discussed.

[@kajkage7613]

why is a random youtuber so much better than a teacher.
hire a lot of these guys insted.

[@hussainbiology]

thanks for appreciation.... Glad it helps

[@soumyasubhasmita9448]

I just searched it after class and huhhhh rescued!!! I couldn't understand anything about it in class but after watching this... I understood it perfectly.... Thanks to you sir..

[@hussainbiology]

Thanks for appreciation..Glad to know that it helps ✌️

[@piglyn6164]

Another example how much more you can learn off RUclips videos than the school cycle.

[@kamalsingh4369]

of which class is this?

[@aaravvijay1707]

My Biology class loves your videos! Especially ur accent when saying atp/adp. Thanks papa

[@nayo2027]

CLEAN EXPLANATION , SIMPLE ILLUSTRATION, 100% UNDERSTOOD. thank you

[@hussainbiology]

thanks for appreciation

[@jeevansiwakoti9955]

Most people who are watching your videos are NOT experts so please explain it like you're explaining to students.

[@hussainbiology]

Surely i will

[@jeevansiwakoti9955]

Hussain Biology thank you bud

[@elliinouye1588]

Thank you so much!!! You described this amazingly!!!

[@hussainbiology]

Thanks Eli for appreciation...Glad to know that it helps

[@xian6361]

Thank you so much for your videos! I understood it better here than in class, keep up the good work man

[@steadystep759]

I was going over my review for my bio exam tomorrow, and this was a concept I didn't understand. However I now understand it, Thanks! 😁

[@hussainbiology]

Glad it helped!

[@alexandermoe3356]

I get it now. I think I just found my savior.

[@hussainbiology]

Thanks for appreciation...Glad to know that it helps

[@rabeelrabi9901]

THAAANNNKKKKK UUUU SOOOOO MUCHHHHHHH ……………. U just solved my whole confusion in just five min …..

[@anshumaansrivastava107]

Thank u from this 14yo kid... Well explanation then my greedy private teachers

[@Nibahazeem]

Thanks for this video 😊😊

[@hussainbiology]

Welcome 😊

[@fahadbaloch5969]

Thanks you so much❤

[@hussainbiology]

You're welcome 😊

[@Ugh_mariaa]

Ngl,it was Superb easy❤

[@michaelsrowland]

At 1.57 why did you put 2 minus signs ? Can you e explain why you are doing this??

[@hussainbiology]

actually if we see its molecular structure we have got negative charge on phosphate,,, that is why....
it should have been for one only

[@avnishyadav4751]

Sir please make videos on mechanism of action of co A, nadh and ATP

[@tusharjadhav2233]

Thanks for your explanation

[@hussainbiology]

thanks for appreciation

[@ValerieKunzi]

Where is Part II? Great review!

[@ABUBAKAR-ko6om]

Thank you so much you described it very clearly

[@hussainbiology]

thanks for appreciation..Glad to know that it helps ✌️

[@mrsurajsmokershorts2404]

One number

[@DisKeda]

Dude. Your statement that ATP releases more energy that it takes to make it is clearly wrong. 1st law of thermodynamics states that energy cant be created or destroyed. The energy used to create the bond in atp is taken from aerobic respiration, a process which breaks the sugar (using oxygen) in order to release energy. Kind of the opposite of photosynthesis, that makes sugar.

[@ScaryGeorgia26]

Making a bond is exothermic, it releases energy. Breaking a bond is endothermic, because energy is transferred to the reactants in order to break them. Making ATP is making a bond, breaking it down into ADP is breaking a bond. The energy that a cell gains from ATP --> ADP is not from the ATP bond breaking, but from the phosphate hydrolyzing. Hope this makes sense.

[@ScaryGeorgia26]

I think he's wrong when he says ADP --> ATP is endothermic

[@Ethan-uq2ew]

@@ScaryGeorgia26 um wdym? isn't it endothermic because you're like giving energy when you add another phosphate cuz the phosphate group stores the energy and it's exothermic when you hydrolyze it right?

[@Ethan-uq2ew]

and you're not releasing energy when you add another phosphate onto adp but absorbing so isn't it endothermic?

[@user-bu8ql3zd6w]

🤓

[@abvlogz1479]

Thanks alots for an clarification of ATP

[@MOHDARSH-er2oo]

Thank you .
Now I understood the process.

[@Arpit6348]

Thanku so much 😀 it's vey helpful for me

[@ivantarnyagin]

Great video, subscribed

[@hussainbiology]

Thanks Ivan for appreciation....Glad to know that it helps

[@asadul22-f3b]

Sir ji I have 1 doubt.... When phosphates have negative charge then why did they get bonded at first? Ye to wahi baat ho gyi ki aap kerosene me paani forcefully milaao aur phir usey alag karke kerosene se enegy nikaalo...plz reply sir ji!

[@jorodino1317]

I have really stupid question......Ok i get how ATF turns into ADT and the other way around .....whit the external and endotermal reaction and the Hydrolysis .....but what is exactly the energy released from the chemical bounds? What exactly is happening.....Can you please answer me?

[@andrewhasbrouck6858]

Thank you

[@Jaikrishna-bc2gi]

Sir plz make video also ATP SYNTHASE and its mechanism 🙏 ur diagram improve my answer writing presentation

[@hussainbiology]

Thanks for appreciation.. Glad to know that it helps ✌️

[@Ethan-uq2ew]

@@hussainbiology lol atp synthase would help a ton for people that don't get it :) you saved my grade's from mass extinction

[@chimkandi2000]

Nice explanation.sir

[@hussainbiology]

thanks for appreciation

[@vikramadityadev7605]

Very good , important concept

[@hussainbiology]

Thanks for appreciation.....

[@jummygay444]

Sar ATP DOP test Ke Niche aata hai kya mujhe jawab dijiye sar

[@chocolatelover1101]

why is ATP reduced? how does it gain an electron

[@Ethan-uq2ew]

becoming reduced is gaining electrons, oxydizing is losing electrons. I hope you get this :)

[@juzy1022]

Great explanation mate

[@hussainbiology]

thanks Justin for appreciation..

[@reenakhandare9803]

Nice teaching 👌👌👌

[@hussainbiology]

Keep watching

[@yasminyasser907]

Release or absorption of energy means endergonic and exergonic ... while in case of heat we say endothermic and exothermic , right ??

[@ytpamile9967]

I think so,.

[@mehulighosh7181]

Releasing heat energy is exothermic n absorbing heat energy is endothermic

[@sohailkazi7036]

How we got one phosphate group??

[@hussainbiology]

The same Phosphate which we lose upon Hydrolysis in ATP is brought back to ADP .....
and still inspite of that we have inorganic phosphate present

[@sohailkazi7036]

But sir..
How why adp is brought back

[@hussainbiology]

ATP gives energy stored in its bonds.....
ATP loses one terminal Phosphate and in that the Phosphoanhydride bond breaks and gives off the energy which drives all metabolic processes...... And then the cell doesn't lose this ADP rather it again uses it in ATP synthase where it is again converted back into ATP.....
ADP does not have much energy as ATP has bcz the terminal Phosphate is unstable and gives off energy easily that is why we convert back it into ATP...

[@rodolfoantopina686]

.

[@vibhu.76]

Can you please tell from where that adp molecules in plants come and the inorganic phosphate??

[@sumairaraes8484]

Thanks a lot sir for helping me

[@hussainbiology]

You are welcome , Sumaira .....Keep sharing and supporting... Shukriya

[@sumairaraes8484]

Hussain Biology May Allah Pak give you lots of success in your life

[@hussainbiology]

Allah bless u too with success.

[@subratdubey2038]

Ming boggling...keep it up

[@hussainbiology]

thanks Subrat for appreciation...Glad to know that it helps

[@RobertLongM]

So there is massive buzz talk about ATP release using supplements, Laser, Stimulation etc...
But no one speaks of the mechanism of getting ADP - Back to - ATP
Are you saying he release of the Pi creates the cell respiration pulling back the Pi?

[@LoafSilkyyyy]

adp and phosphate can be converted back to atp by condensation.

[@davemembrere6972]

Thank you so much...

[@sheeba8184]

Why is the energy released greater than absorbed as mentioned in the end of the video ?
Thank you

[@hussainbiology]

See , there is a lot of chemistry going out there but i will try to make it simple
The released energy upon breaking of phosphoanhydride bond is always greater than the absorbed is bcz the energy released depends upon the reactants that is here ATP and Water .
During the Hydrolysis reaction the reactants (ATP and water) themselves have high energy relative to the energy of the products (ADP and Pi) that is why we get total energy gain plus also the instability of terminal phosphate due to charge repulsion between the adjacent negatively charged phosphate groups also adds to the releasing more energy .

[@hussainbiology]

The bonds between the phosphate groups of ATP can be broken by hydrolysis.
When the terminal phosphate bond is broken by addition of a water molecule, a molecule of inorganic phosphate leaves the ATP, which becomes adenosine diphosphate, or ADP (Figure 8.9b). The reaction is exergonic and releases 7.3 kcal of energy per mole of ATP hydrolyzed:
ATP+H2OSADP+~Pi
ΔG = -7.3 kcal/mol (-30.5 kJ/mol)
This is the free-energy change measured under standard conditions. In the cell, conditions do not conform to stan- dard conditions, primarily because reactant and product concentrations differ from 1 M. For example, when ATP hydrolysis occurs under cellular conditions, the actual ΔG is about -13 kcal/mol, 78% greater than the energy released by ATP hydrolysis under standard conditions.
Because their hydrolysis releases energy, the phosphate bonds of ATP are sometimes referred to as high-energy phosphate bonds, but the term is misleading. The phosphate bonds of ATP are not unusually strong bonds, as “high- energy” may imply; rather, the reactants (ATP and water) themselves have high energy relative to the energy of the products (ADP and ~P ).
The release of energy during the hydrolysis of ATP comes from the chemical change of the
system to a state of lower free energy, not from the phos- phate bonds themselves.
Source : Campbell Biology 10th Edition

[@hussainbiology]

and if u love chemistry then someone here on Chemistry stack exchange has answered well it in chemistry language :
ATP is not broken in a vacuum, but hydrolyzed by water, which is disrespected and not shown in the reaction pathway, but is hugely important. The overall free energy of delta G remember is not just the enthalpy of the reaction (heat given off or absorbed) but also composed of an entropy which is the ordering or disordering of the surrounding solvent water molecules. It takes far more water molecules to be ordered around the ATP gamma phosphate once it is released in the ADP + P form than in the ATP form when still attached. Energy is always required to break bonds and always is released when bonds are formed, even with ATP, but the part that is omitted is that more molecules of water are bound and ordered after the ATP hydrolysis than before and so more ordering plus many more highly energetic hydrogen bonds formed than broken equals a large overall release of energy for the overall process. Don't forget the water!

[@sheeba8184]

Hussain Biology Thanks a lot !

[@hussainbiology]

You are welcome Sheeba.... Keep sharing and supporting...

[@Yara-fp4vt]

Really awesome ❤

[@hussainbiology]

Thanks Yara for appreciation

[@andrewhasbrouck6858]

So you are always losing a little energy every cycle

[@thulukkanamk4288]

Super sir😙😘😘😘😘😘👍👍👍👍👍👍

[@hussainbiology]

Thanks for appreciation...

[@sumairaraes8484]

Sir inorganic phosphate ata kaha se hai aur adp ko atp mai convert krnay k lye energy kaha se ati Hai.. cellular respiration mai atp bunti hai jo khud energy hai adp ko p se combine krnay k lye kahti se energy ati hai

[@hussainbiology]

Basically the free energy of Protons is used to drive the conversion of ADP to ATP in the process of Chemiosmosis.
if you remember In ETC the free energy of electrons is used to Pump Protons to inter membrane space of mitochondria and then the Protons and sent back to mitochondrial matrix via ATP synthase which uses the free energy of Protons to drive the synthesis of ATP from ADP + pi.

[@nasreenakhternasreenakhter5488]

H

[@SSB_TATS]

Thak u bruh

[@somadak8535]

why do ATP need to convert in ADP please explain

[@hussainbiology]

Bcz , in order to do work we need energy, In the same way our all metabolism processes needs energy ( fuel ) to go on. So for this the ATP has stored energy in there there bonds between Phosphates. The terminal phosphate of ATP breaks upon hydrolysis thus releasing energy and itself gets converted into ADP.

[@tomboycosmas842]

Is this ATP can not release energy untill converted into ADP? Plese help..
Bt u presentation is👍

[@hussainbiology]

@@tomboycosmas842 ATP releases energy upon Hydrolysis and in that process of releasing energy it gets converted into ADP.

[@raguv-_]

Can i edit your thumbnails 😊

[@hussainbiology]

yes...

[@sumanyadav8166]

Where does a organic phosphate come from

[@rubaabkhan6253]

nice bro..keep it up..

[@hussainbiology]

Thanks buddy for appreciation..

[@bhatsuriya172]

thanx dear...very helpful

[@hussainbiology]

thanks dear.....

[@saedyusuf2143]

Nice

[@hussainbiology]

Thanks

[@nickysrivatav7760]

Thanks

[@janajarathanan4186]

Super

[@AnujKumar-dl9nu]

Please try to tell this topic in hindi

[@avnishyadav4751]

Please

[@sadafkhursheed2448]

Are you from kashmir

[@hussainbiology]

Yes Sadaf i am from Kashmir ✌️✌️

[@shaikhsaniya5346]

Sir not understanding properly

[@hussainbiology]

Where i can help ? aap bataye kahaan pr samgh nahin aaraha

[@rakshitbajaj8929]

🤩🤩

[@aimenzahid6889]

No of ATP formation in algae

[@hussainbiology]

You can't generalize the number of ATPs generated in Algae.
Like In Glycolysis we get 2 ATPs and If There is fermentation in Algae we further get 2 ATPs
Click link for more information :
www.ncbi.nlm.nih.gov/pmc/articles/PMC3660698/

[@aimenzahid6889]

@@hussainbiology sir here giycolysis process is explained but in algae ATP formation occur in mesosome glycolysis ,kreb cycle and fermentation not occur i think
and also the link you suggested i only write Abstract ( for ATP formation in algae) plz sir replay fast

[@hussainbiology]

If u are talking abt Cyanobacteria ( that is Prokaryotic Gram negative bacteria which is termed as Blue green algae)
The Fermentation , Occurs in Chlamydomonas that is Algae

[@aimenzahid6889]

@@hussainbiology I am taking about blue green algae

[@hussainbiology]

@@aimenzahid6889 That is Cyanobacteria to be precisely....A Prokaryotic Organism.... you confused me with Eukaryotic Algae

[@ur1299]

You sound like you're a Kashmiri?

[@hussainbiology]

bcz i am Kashmiri that is why i sound like Kashmiri😁

[@ur1299]

@@hussainbiology That's great sir!

[@ur1299]

@@hussainbiology proud to have teachers from Kashmir

[@hussainbiology]

@@ur1299 thanks buddy

[@CashFlowChris_]

Does anyone know the connection between the structure of ATP and how is it processed in our cells?

[@LoafSilkyyyy]

a five carbon sugar called ribose,a double ringed molecule called adenine and three phosphate groups linked in a chain called triphosphate group,and ATP is able to power cellular processes by transferring a phosphate group to another molecule (a process called phosphorylation). This transfer is carried out by special enzymes that couple the release of energy from ATP to cellular activities that require energy.

[@ajaysharma6811]

Kashmiri accent

[@hussainbiology]

Yes sir..✌️✌️ Kashmiri here

[@aimenzahid6889]

Plz.......... replay fast

[@abdullahsarwar402]

Pa g Urdu ma video bana lo

[@zoltanpinter2762]

NEM ÉRTETTEM AMIT AKARTAM

[@sunitalarokar5887]

Angrej bnne ki puri koshish ho rhi hai.

[@asadul22-f3b]

Koi h nhi na adenosine triphosphate ko hindi me translate waala

[@franciscogrosch8275]

too indian

[@amunatz5236]

stfu