ATP synthase in action
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- Опубликовано: 29 сен 2024
- In this animation, Professor Rob Lue describes the action of the ATP synthase.
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How about a course on how to discern and verify the accuracy of the model ?
@@paddlefar9175 I would like to have a new house with a parking garage for the new car too for free.😁
This might be the coolest thing I have seen in a very long time.
This is crazy stuff! :)
This course changed my life, thanks 🙏
This was something that always baffled and frustrated me in college bio, for which my professor didn't have an answer. "Why does ATP synthase rotate? Wouldn't that cause a loss of energy? What purpose does it serve?". But your explanation cleared that up marvelously after nearly a decade. Thank you.
When you study Electron Transport Chain, 2 forces make that C-Protein rotate. First is the Concentration Gradient, Second is the Electrical Gradient (Negative Inside in the matrix, and positive on the intermembrane). Those 2 forces make the C-Protein rotate just like how Air rotates windmills, and Water rotates motors in dams. In the process they clamp ADP and Phosphate to become ATP. Simple.
well in my book (German version of "Fundamentals of Biochemistry - Life at the Molecular Level. Fith edition" by Donald Voet, Judith G. Voet and Charlotte W. Pratt) the reason for the rotation of the c-ring, im parafracing and translating here, is due to a conformational change in the c subunits caused by binding a proton. And possibly some electrostatic forces.
@@Nobbu thats right thats what the other reply said aswell, voet possibly the best biochemistry book imo
You sound like a physics major.
@@hadrielvalentino may you explain to me the concentration and electrical gradient?
Man: *Invents turbines to produce energy* "Ha Ha ! I'm so smart !"
4 Billion old cell:
4 Billion old Cell ? NEVER!! Blindly believing Lies!
Im more baffled by how life (that can not see anything really, only feel its way forth in the darkness of any type of tissue) has somehow ended up in this. Like what the heck even is that how did evolution give it this design for extracting energy like wthhhh🤯🤯
Life existed as only single cells for a Billion years before even the first plants and animals evolved. An unfathomably long time for natural selection to act at the microscopic level 😵💫
@@yoongilimerence the fact that life even exists is insane dude
@@HummusPvm Nothing within inorganic chemicals and minerals created life, nor did it somehow write all the code for how it all works in the DNA. Supremely complex.
ok..well thank you YT tell me what i am watching now and where i am..? felt into rabbit hole again
When the video talks of protons as driving the rotation, is that a hydrogen atom that has been stripped of its election, and how does that gradiant keep getting created
That happens in the krebs cycle
It is absurd to think this was anything but intelligently designed. To think otherwise is tantamount to saying a computer was not intelligently designed. Our body is saturated with machines. The complexity is staggering.
personal incredulity arguments wont get you anywhere
This seriously show the fierce fight life has to put against entropy.
@Electro_blob 2 it could, but it's so unprobable that id rather believe a sentient space pizza engineered it.
@Electro_blob 2 A bunch of space gas (plasma) didn't turn into this. At *least* 99.9999999% of it is still space plasma or rocks. Entropy on Earth may have gone down, but the entropy of the rest of the universe has steadily been increasing. Life has been on a treadmill running from it for three billion years.
@David Vega Blasphemy!! We all know that the true heavenly Italian food is his noodliness!
lol life isnt fighting against the entropy of the universe. Life is something the Universe itself is doing.
@@lordoftheflings life is about survival. maximum entropy means no more life. which means in a way life IS about fighting entropy.
@@lordoftheflings Yeah, the Universe did kinda create life, but it's also trying to constantly destroy it. Like humanity.
This thing spins at 130 times per second! In some species it even goes at more than 700 RPS!
Proton minigun
7800 RPM, like a high-performance engine.
Only? I was expecting it to go around at millions or billions rotations a second
@@_John_P i was expecting it to turn 1rph
@@eien7228 Why?
How the hell did this evolve???
Look up the bacterial flagellar motor 😅
Oh, Please!
Time magic of course
through billions of years of trial and error and even now it is imperfect
@@Auricalioshow is it imperfect hahah
It acts like a turbine! A proton-powered turbine!
About 33 times per second. About 2000 rpm... Nice
@@mkrzyzowski 130 rps. In some species, it can spin more than 700 times per second.
@@jascrandom9855 Wow. Pritty fast. I expect those spieces live fast and die fast. Is not that?
@@mkrzyzowski No idea.
This is happening at the quantum level so it's not like you can draw analogies to our macroscopic world. The molecules wiggle around as fast as quantum mechanics wants them to.
Amazing how ‘mechanical’ it essentially is. How could it not be.
I always saw cells like that: tiny bio-machines
It literally is a molecular machine. A molecule that interconverts chemical energy and mechanical movement.
Only in the last few decades chemistry has started to create artificial, synthesized molecular machines. The pioneers of this area won the Nobel prize a few years ago. It's a really fascinating subject.
By design
I cannot fathom what steps this went through to evolve like this.
@@jackb3493 a whole lot of failure for a whole lot of years
This tiny engine is 99% efficient by the way
Why 99?
@@lennintapia6761 heat, you can't be 100% efficient
Tell me when it gets to 100 and we're immortal
Holy shit!
Is there a catylizt?..this surprised me..are many bio - systems that effecient ? I'm used to 30-40 % ..
I have no idea why I'm watching this.
Watch it again with 2 years of updated wisdom 🙃👁️
I always loved the mechanism of ATP synthase, probably one of the first times I truly understood how incredibly complex and exact every mechanism in us has to be. Incredible to think we exist only because so incomprehensibly many small chemical interactions just so happen to be thermodynamically favorable.
No offense but you understand shit. There is nothing chemical about chemistry, its interactions or ATP synth. Its ALL electric. Its the "protons" in the simulations, little space for papa Hydrogen. For some miracle it does briefly mention CHARGE activation and hell yeah, notice how there is no OXYGEN anywhere!! For the next time they bluff you its AIR you breath, when its really the electric connection to the mighty BLACK (electric) SUN. Remember the AETHER Einstein erased only to change nothing but to put his stupid name upon...the freaking space-time! Told ya.... little truth and it sounds utterly insane to thee :D. Still better then the official crap, thermodynamics vs gravity driven universe :D
Yes, Jep! And while these one-in-a-million fortuitously thermodynamically favorable structures were miraculously synthesized by blind chance, something probably even more complex conveniently destroyed all the evolutionaly mistakes that logic demands occurred a million or billion times for each fortuitous chemical mechanism that came along.
@@robertecarpenter and Jep- Is it perhaps not so blind that something so complex and fortuitous occurs billions of times with precision? The implication is a process designed intelligently and deliberately. But I am replying with a straight response. Perhaps you were being sarcastic and wanted to rhetorically indicate the same thing. 😁
@@thomascutlip6711
yes, Thomas. I was being sarcastic. to think that billions of fortuitous mutations could accidently form something as complex as the TP Synthase motor, is ludicrous. That means that trillions of detrimental mutations would also have occurred. Did they just magically vanish? Did some guiding hand dispose of them while gathering and directing the good mutations toward a goal? I agree with you 100%. This incredible, irreducible complexity cries out for an inexpressibly intelligent Creator.
@@robertecarpenter 1) That means that trillions of detrimental mutations would also have occurred. Did they just magically vanish?
No, they simply were not successful, so probably died.
2) Did some guiding hand dispose of them while gathering and directing the good mutations toward a goal?
No, the bad ones simply were not as good at surviving, therefore died. The good ones were betters, so they lived.
Not F-zero. Its Fo, for Oligomycin sensitivity!
Just scrolled through the comments to see if anyone had already pointed that out. Thanks to you!
I guess if you want to know if there is possibly anything wrong with anything you made → subject it to the criticism on the interwebs. xD
I wish I understood this stuff a lot more 😭😭😭 I feel so uneducated 😭🤐😔
Life is motion... the motion of an ATP turbine.
No all living organism have these
@@sklefenz Nothing in his comment suggested otherwise.
@@sklefenz not all organisms are as complex
@silent-lee It's still at 69 lmao
This is so awe-inspiring. I wish they had animations like this when I was in High School.
Did you say highschool???? You think this is highschool stuff?
@@justinbishop54 bruh 😭 i wish this wasn’t high school stuff for me, we had one week to make a video project of how ATP synthase works
I am watching this in my 10th grade😅
@@bijaya1109 8th
Hi there! Quick note - the bonds that hold the phosphate groups together in ATP are phosphoanhydride bonds, not phosphodiester bonds! Thanks for making this lovely animation, it's very helpful for teaching biology!
thank you
The first phosphate that attaches to the sugar is by an ester bond. The consequent 2 other bonds would be anhydride bond.
@@praneeroop a phosphoester bond not phosphodiester bond though
Gorgeous illustration, wasn't it? This is the best kind of biochem animation. Super.
Thanks for !
This is one of the most beautiful videos on the internet; not sure why more people haven't seen it. Fantastic work and thank you for making the world a smarter place!
This is deeply complicated and beautiful. My eds mashed
it's complicated but not difficult, it helps to compartmentalize the subject matter...personally, i watch the video -- the 1st time, in its entirety, then i replay it... hear a point, pause and reflect, making certain i understand each point right down to the the verbrasity ...then cont when you feel you understand it. i'm auditing the course and although i already have a background in science, i find the course stimulating; especially when i pass each test with flying colors
@@Carlzday yeah I agree it's not actually a complicated concept it's just an in depth explanation you could have learned this in high school
This video cured your erectile dysfunction ?
I really like the lipid hydrophobic tails here.. eye catching I must say.
This is what i call a nerd comment section. My deepest admiration
When you get a glimpse of GRAND ENGINEERING by a Higher Power.
I make a point of trying to understand something outside of my knowledge base at least once a week. I find it helps me in myriad ways, not least of which is in being a better teacher and student. I think this was a very well put together video. I didn't struggle as much as I expected to in comprehension, and was reminded of physics basics I hadn't thought of in quite some time. Thank you for putting this together!
@@paddlefar9175 But chemistry is dictated by the physics.
Biology is Chemistry with context
Chemistry is Physics with context
Physics is Maths with context
Maths is logic with context
when are we going to have ATP powered cars and rockets
All chemistry is fundamentally electrical in nature as it is entirely due to charges of the atoms in molecules and the exchange of electrons or positive ions.
Chemistry is just atomic physics. Not sure why they're split into separate arbitrary "fields".
@@dolebiscuit I think of it more like a nested hierarchy, simply because knowledge itself is such a vast 'field', that it can be sub-divided quite a lot just to make it manageable for us to comprehend.
For example, the entire 'field' of biology is contained within just a subset of organic chemistry.
Just wonderful! I remember learning the Krebs cycle at med school but this is unbelievable stuff. Amazing work!
How to build a Proton Minigun
Oh my. This is engineered! No way in hell a mindless process created this. Seals, rings motors, stators, etc. If you scientists keep this up, I am going to have to start believing in intelligent design.
Of course it's designed, anyone with a functioning mind realises that.
@@paddlefar9175
To be fair, I did say a functioning mind, not a chemical brain, evolved solely for survival rather than truth, guided purely by chemical reactions, completely devoid of free will to say, or not say nonsense ?
It’s more or less the same as the infinite monkeys with infinite typewriters eventually producing Shakespeare. Trillions upon trillions of unique single-celled species existed before the mitochondria came into being. Mitochondrial factories in cells was just the Shakespeare moment. And now they’re everywhere, because they’re just better at living than cells without mitochondria.
I guess if you wanted to extend the analogy through the present day, that technically means we have to throw out all the monkeys that didn’t write Shakespeare and force the ones that did to breed, creating monkeys more predisposed to writing Shakespeare. But choosing which monkeys make more monkeys isn’t the same as making the monkeys from scratch.
@@sparkyy0007 So what you’re saying is that people can have different types of brains just by believing they do? I can see why you believe in intelligent design.
@@dodiswatchbobobo
"So what you’re saying is that people can have different types of brains just by believing they do? I can see why you believe in intelligent design."
No... brains and minds are two completely different things; we all possess both but 2.7% of the population refuses to acknowledge the latter, because they refuse to acknowledge the creator of mind, God.
In naturalistic terms, a brain is nothing more than a vast array of chemical switches, and because of that we could theoretically emulate the functional process of a brain in it's entirety with water pipes and valves, just as we could with any computer.
Indeed it would fill the orbit of the earth to emulate a single brain, but it would be a valid materialistic surrogate.
Yet we all know full well it would only ever be a huge pile of pipes and valves without the consciousness our minds enjoy.
Scale.
Our brains contain 86 billion neural nodes each with up to 10,000 interconnects.
Conversely, the internet contains 50 times more nodes, and yet it has never, nor will it ever become self aware... it's just a big calculator.
Our mind is far more than a meat robot of chemical switches.
Consciousness is a metaphysical property which separates us from machines...meat, mechanical or silicone.
If we were simply chemical brains as naturalism would dictate, we could have no warrant to truth, reason or free will.
You can't justify or hold to any truth under naturalism.
All glory to Jesus alone for His beautiful creation!! Bless His mighty name 🤩🙌🏾
"It just works."
get out todd, enough internet today for you.
This is amazing, just like how amazing and complex life is.
This molecular machine caused me to contract Deism. 🤷♂️
A multitude more of these complex machines that work synergistically to allow a human body to live and take high-level orders from the person insde.
I've always found every description of cell biology mechanisms simultaneously overly descriptive and also not descriptive enough. There needs to be much more "how/why/for what purpose" and less "this is x,y,z"
Looking at life on various levels... I think I am beginning to understand how a bunch of dead stuff can constitute a living thing.
What millions of years of evolution dose
That's cool and everything but did you know that *the mitochondria is the powerhouse of the cell* ??
atp synthase is on the mitochondria I believe
New England Yes its located on the inner membrane of the mitochondria, if I remember correctly.
Hi
i always wonder how humans are able to discover this...
What i want to say: It blows my mind
Doing my final year degree course i read the description of the electron transport chain mechanism over and over again. Brain just wasn’t getting it. Watched something similar to this. Ah!!! I get it.
Yes, it is similar to learning that Moon does rotate yet we only side the fixed side. Explaining it in text with illustrations makes it difficult to comprehend, but using physical models works.
as a Darwin worshiper I am not sure how evolution, which is driven by randomness, explains this
The amount of chemistry and research behind this vid (and without even mentioning the incredible image processing technology) is just staggering. But even more amazing is trying to understand how all this came about through blind random chemical evolution. Foisting these miracles off on supernatural or extra terrestrial intelligence is ridiculous, but it's hard to escape the feeling that there are other vital organizing principles at work here of which we're completely ignorant. The idea of shaking a bag full of gears and springs until a working clock falls out is really not all that far off from what Nature's done here.
It's not really that crazy to imagine. Humans already use evolutionary algorithms in ML and they learn pretty wild stuff. If we imagine that one of the most significant evolutionary pressures would be energy metabolism, then it makes sense that evolution would learn it complex machinery to make it as efficient as it can.
There are five million trillion trillion bacteria on Earth right now. In a sense, the nature is running the largest parallel learning algorithm at scales it's hard to even comprehend.
Plus, a lot of the stuff we, humans, use is pretty ancient, even our psychology relies on ancient biological machinery. Once a useful building block is found it is used for many things and eventually more complex building blocks are found.
This is why we can study facts about human memory on creatures as different from us as fruit flies, or find that c elegans has neurotransmitters like dopamine or serotonin.
Imagine shaking a bag full of gears for at least 14 billion years, what about 500 trillion years if it could be possible for these to escape relapse in reformation of universes
"Foisting these miracles off on supernatural or extra terrestrial intelligence is ridiculous."
Actually, 'foisting' this on a supernatural intelligence is the simple, occam's razor answer. It takes incredible mental gymnastics (and many years of indoctrination) to so easily credit evolution with this. If you can realistically lay out the step-by-step evolution of such a system (and every other highly complex system), along with reasonable evidence that your 'just-so' stories actually took place, only then can you start to say that evolutionary explanations get anywhere close to being as plausible as supernatural explanations. Paul wrote 2000 years ago that creation makes it obvious that there is a God. 150+ years of mind-blowing scientific discovery could not more powerfully reinforce such a notion.
@@MyLuggage12345 No, it's not. Because then you still have the same problem of apperance of that supernatural intelligence, you just push it on another level. You don't want to believe that biological machinery appeared by itself and want to believe that it was created, yet you believe that God - the thing presumably a lot more complex and powerful that this biological machinery as to be able to create it - appeared out of nowhere by itself.
Moreover, if you go the creation route, why not say that there exist a Supergod too, which created God which created the universe? Or Меgagod which created Supergod which created God, which created the universe? This is how spawning unnecessary entities looks like.
It's just easier to say that the universe appeared by itself or always existed, than spawning additional entities which would also have to either always exist or appear by themselves.
Whether or not random evolution produced life in all its manifestations, the marvelous thing is not that life appeared, but that life is possible. To expand on this point: the marvelous thing about reality is not its contents, but its inherent (essentially unknown) possibilities. I think that, if there is a God, theologians miss the mark by designating him/her/it as pure actuality. Far greater (infinite?) is pure potentiality, which likely is not constrained by what science presently tells us about the universe. Bottom line: I designate the infinite potential of the universe as God; whether he/she/it is also intelligent as we define the term, and is monitoring and/or directing events, is beyond our ken.
That we have so little understanding of "basic" functions and waste money on space exploration is mind boggling.
Athiests be like “yeah this massively complex mechanical system just randomly started existing in a pool of rocks”
No, that's not how atheists be at all.
No, that's not how atheists be at all.
@@TheZahirNT2 pretty sure that’s what they be like
Your quote is stupid. Atheists on the other hand are smart.
This complex system of course did not randomly started existing but evolved through a long chain of reproduction, mutation and evolution.
@@antagonizingusername are you basing that on personal interactions you have had with atheists, or on caricatures presented to you by churchgoers, people online, and RUclips videos?
Or are you just trolling? We could have a productive discussion, but I suspect you are just trolling.
Me as a kid: "yeaaaahh lets go!!! the mitochondria is the powerhouse of the cell."
Me growing up:" how silly lol, surely its more complicated than that stupid analogy. Makes for a good meme though."
Also Mitochondria:
* literally a dam, has everything:
1. Wall (inner mitrochondrial membrane)
2. Reservoir (intermembrane space)
3. built-in electric cable line (ETC) to run water pumps
4. water pumps to refill the reservoir (H+ pumps)
5. Floodgates installed with a waterwheel (ATP synthase)
6. Stores energy in drained batteries (ADP) *
Me at university: "the mitochondria...is... the powerhouse of the cell?"
This is happening in your body right now and there's nothing you can do about it.
If you want it to stop, there's only one way...
Why would you want to do anything about it?
@@BlunderMunchkin Because consciousness is a curse.
For those who are thinking what is this, it is an enzyme which makes ATP (energy currency). Without ATP you can't think or even move a muscle. So use that ATP and support a bro!😂
Time alone can create such a complex structure.... if I leave my homework alone it could get done by itself, right?
At what time did time create time?
@@hfarthingt That's an invalid recursive question. Simpliest answer, time is an intrinsic part of space/time and did not create itself.
Your homework would slowly decompose into dust and no amount of chaos would even begin to attempt to start it. But you knew that already.
@@SpaceCadet4Jesus Similarly, no amount of chaos would ever attempt to build up even a single cell. The complexity of graphene marks on a piece of paper is infinitesimally less than the complexity of the simplest living organism.
Only if your homework reproduces.
Cells knew how to perfect movement, rotation, engines, etc... Before Humans.
@@idlehour Cells don't 'know' anything more than a tamagotchi.
Hats off! You just cleared my three years old confusion within 5 minutes.
Visual learning is something on another level🔥
The Bible says that the Lord created only us Humans after his own immage, so if we Humans are created after God's own immage, why do Earthworms, Spiders and basically any other living beings have this IDENTICAL biological machinery inside them? If God made us so special and unique shouldn't we also have special and uniquely biology? Instead we share the same molecular machinery like Earthworms!1
Always loved this thing. The fact that our main energy packets are made by basically motors rotating really fast is amazing
JAGO RECEP BERBER EN İYİSİ :DDDDD HERKES JAGO BERBERE GİTSİN :DDDDDDDD EN İYİ BERBER JAGO BERBER :DDDDDD JAGOKRAL BERBERLERİN PİRİ ŞAHI BERBER ATATÜRKÜ
Thank you so much for the simulation! I really enjoy science videos and this is a great place to learn more :)
(i'm doing AP bio right now btw)
gotta love having 5 of your comments removed because you angered the youtube algorithm, anyways.
I was never a big believer in God until I majored in biology, specifically cellular biology. None of this should be happening due to atoms and molecules just banging into each other randomly. please.
So a blind process, with no governance system figured out how to seperate protons from atoms for fuel. Then seperate other atomic particles and add others to create a new compound.
Absurd.
The animation abs simulation is amazing. Please do more simulations like this esp with what’s going on in the organelles during sugar uptakes or lack of oxygen etc
It's crazy to think how just given certain conditions and enough time THIS will emerge on the lifeless planet.
Abiogenesis will always be more beautiful and awe-inspiring than "Magic put us here."
I dont even know basic chemistry,hell o can't even spell it why am I watching this at 3 am
A germam guy curiosity, embrace it my friend.
2:09am here brother, no idea either.
Its 5am, and I´m still up watching this for an 11th-grade paper
but do you still atheist after this video?
@@ВасянНирванов Yes. This video alone is not enough to convince me otherwise. In fact, it actually strengthens my position.
i went from "mithocondria is the power house of the cell" to "mythocondria is the hidraulic power plant of the cell" real quick
Beautiful Design
And designed it is.
سبحان الله الخالق الذي خلق فأبدع✨
As an engineer, is amazing watching all the mechanisms in play in life. There are things to learn just for every field of engineering. And in most of the cases, life beats human engineered systems. We can see in biology applications for the following engineering areas (the list can be much longer!): electrical engineering, computer engineering, mechanical engineering, thermodynamics, control systems, communication systems and protocols, artificial intelligence, programming languages (DNA), algorithms, sensors, computer vision, memory management and hierarchy, structural engineering, actuators for both power and finesse, motors, hydraulics, fluid dynamics and piping systems, valves, safety systems, redundancy, cameras, energy production and management, waste management, automatic maintenance, force sensors, digital signal processing, audio processing, natural language processing, and so on. Machines do not appear by accident.
Evolution had hundreds of millions of years to find through trial and error what works the best.
@@DoctressCalibrator You need way more faith in the religion of evolution than intelligent design.
@@46I37 Sounds like something someone without any knowledge of evolution would say.
@@DoctressCalibrator well, I've design complex electronics systems for 30 years, and that requires meticulous intelligence. These systems are orders of magnitude more complex in design complexity. No way that's happening through random mutation. Irreducible complexity is the first of many nails in the coffin of evolution.
@46l37 And how many years of experience do you have studying the evolution? I'll take a wild guess at the number being "zero". If it actually was intelligent design, would we be seeing incredibly stupid ways evolution had gone to because of heredity? Recurrent laryngeal nerve, for example, or our own spine and thigh joints? Why is RNA used in the rhibosome, when everything else catalyst-related is built out of much more reliable and stable proteins, leading to significantly increased difficulty in assembly and reduced durability of rhibosomes compared to their theoretical protein-based counterparts? Look at how huge it is compared to any purely protein-based enzyme complexes like ATP-synthase, DNA and RNA polymerase, or even the chaperone complex. Yet despite its blatant issues, not only is it the primary protein-assembling enzyme system for all cellular life we know, it's quite possibly the most conservative element of translatable DNA code.
How, precisely, is your lack of knowledge in the field of biology allows for such arrogance that you're willing to utterly dismiss some 3.5 billion years of biochemical change before we get to the common ancestors of these molecular systems, or centuries of work done by people before your field of work even appeared with the invention of the transistor, and continually done to this day? Good old Dannig-Krueger strikes again, it would seem, and knowledge from a tangentially related field leads to belief that you somehow know MORE than generations of people who dedicated their entire careers to it. Know what it looks like? Waltzing into an engineering meeting for CPU production, and telling them that they are idiots for working on an x86 processor because it's "CISC". There are *incredible* amounts of utter, *utter* stupidity that got retained in the evolution process simply because there's no Ctrl-Z, on all organisation levels, from molecular to organism. But no, no way these molecular mechanisms could appear in the over 4 *billion years* that life existed for in some form, sure.
EDIT: Wrong reply tag.
Thank you for the animation it is marvelous, it is quite difficult to see only a image in the books, but, now, I can understand how the ATP is synthesized.
It's like some mechanical device but made of protein instead of steel
I have just discovered this video today, and I am awed and amazed at how fantastic the biochemical machinations that we have in our cells... words cannot describe it completely, but this is one of the coolest things I have see. Thank you for this!
i'm surprised wheels exist in nature
There is some really damn cool animations of DNA duplication and protein synthesis that are even better. made than this. I. really recommend looking that up.
I suppose one way to look at it is that we (our conscience) are just nothing more than a secondary, an effect basically while our bodies and everything that makes it all up are really the primary and cause of what we are.
How can one deny creation?
how the hell did we figure this stuff out
ChronoSquare 70 years of advanced research by thousands of PhD level researchers at full time on the subject ...
@@SEVideoQuant Hi I was going to ask the same thing but fearing a generalistic answer, it´s not like your are wrong, off course that´s absolutely right, BUT I would like to know something more about the process of discovering this type of things, do you know where I can find scientific divulgation for normal people like me to undesrtand how is the process to figure this kind of abstract and contraintuitive stuff for our normal brains? Because if a normal person can understand the process and the logic of the researchers maybe the same normal person will truly value their work and it would be a less flat earth person and a more logic person, don´t you think?
titow205 What is your school level (depending on your answer i will propose you different books).
Read the original research papers on ATP synthesis
@@SEVideoQuant Hi! I'm a 4th semester student of Biotechnology. You got any recommendations?
For an biologist like me, this protein is one of the most beautifull thing existing.
increasingly interested, so much easier to learn at the level i need when i understand a more in depth version of the process, great video
When I saw this I knew there had to be a God.
You really can’t understand how this can evolve? You gotta be kidding me
@@tf3confirmedbuthv54where does evolution begin then?..where does life begins?..can't simply pop into existence right?..DNA is what evolves..but then what was the first genes like..try googling "minimum genes"..
Well that's not at all awe inspiring.... ☺️
2:50 I wish I could shrink down and observe this in real life, real time. It's crazy that no living thing observes this, and we're only starting to be able to understand what happens at such a small scale.
It would be a frantic blur of whizzing activity, and this simulation is slowed-down in the extreme. But this is all academic anyway as human vision wouldn't work at such tiny scales, even if somehow shrunk to molecular levels.
@@hgbnkbggj2915 yup. I know that. That's not my point though. Thanks for playing along, the receptionist will give you your gift bag on the way out.
"We"
The average person wouldn't even dream of something like this 🤣 these things are basically discovered by geniuses or really smart people who work in groups to understand, then this info is presented to the average person, some understand and some don't.
we need to advance in the study of quantum physics to fully understand biology.
agree lets all study!!
Amazing video... clarified quite a lot for me! Thanks!
Very complex molecule is doing a very complex job in every millisecond!
I'm ignorant to all of this on an academic level, but still feel rather-informed and found this fascinating.
Hay 👏👏👏
Ok, so who can tell me with a straight face that all this just evolved by itself, through a purely random, undirected, creator-less process?
From my knowledge it’s been proven that this is now how proteins and cell stuff works.
Proteins aren’t solid either.
Evolution isn't random chance... It's small steps, building upon each other. What works is kept, what doesn't gets lost in history.
Similarly to how human inventions work, really. A cavman didn't wake up some day and decide to create an F-35 fighter jet. The caveman might have, through chance, stumbled upon fire. And someone else finds a way to mak firee hotter, and that was kept. And someone else finds that you can melt metal with fire, and that was kept. Then other people find ways to make better metals, other people learn to make sharp objects out of them, other people attach them on sticks, next person makes a wheel or a bow etc...
Evolution works in the same way. All it does really is keep the good "ideas" (random mutations) that spawn - but thee same way that a bunch of tiny steps can lead from fire and wheels to and F-35, a bunch of tiny steps can create increasingly complex organisms. And natural selection simply does the important job of keeping the stuff worth keeping, which allows new "innovations" to be preserved (as they increase survival), spread and be itterated upon to create something new.
What an absolute perfect piece of engineering
do you believe in evolution after that?
@@ВасянНирванов you can read my article on habr about that: Эволюция - религия современности
I agree. It's not so much what the thing does but that it knows what and how it suppose to do these things.
@@kyleebrahim8061 it doesn't "know" it does because if it didn't it wouldn't exist. life is self asembling and therefore inevitable on earth-like planets and with milions of years of trial and error natural selection all but guarantees complex life
@@dr.cheeze5382 there's no proof for self assembling life but if you have it and it attains to the human species I'll be open to it and if you can name an earth like plant while you're at it
This is beautiful im crying🥲
I cannot believe there is not a creator who intelligently designed this
A few billion years is a long time for chemistry to get its shit together
There are many examples that speak against intelligent design, like in human anatomy (see wikipedia 'argument from poor design'). So why would anyone who can create something so complex, screw up so badly in other (far less complex) areas? Explain that to me ;)
@@jamaly77 First off thank you for giving me the Wikipedia reference to give me something to work off (: not many people cite stuff that's worthy these days lol
But to start I'd like to say that hypothetically, if God did make man in his likeness, and then let people procreate for a BOATLOAD of generations after the fall of man, surely in the passing down of genetic information over and over and over and over again, some stuff would mess up.. Everything decays at some rate that is affirmed by science. The fact that we are still able to pop kids out and have them turn into people that can think live and breath like you and me is INCREDIBLE.
But as for the arguments from poor design.
If you read that again you will notice something that stood out to me immediately.. everything in that is related to humans is either a "rarely" or a "barely" idea
The fact that *some* babies need C sections would not prove that birth itself is poorly designed, it would make sense that perfect information has degraded to no longer be as efficient as it was after so many generations of humans infected with sin (please note that's my opinion:)
For the wisdom teeth portion, it says in the bible (I have to use this as my source lol but don't discount this soley for that) that people lived to be around 900 years old pre-flood. If that is the case then humans would've had a lot of time to grow and change. If wisdom teeth now cause problems, it doesn't necessarily mean they did for our ancestors.
"Barely used nerves and muscles" once again, just because we don't need them now doesn't mean we didn't used to. I mean yeah muscles around the ears probably didn't do too much but I don't think anything 'good' would come out of losing em. The muscles in the foot being useless now could be a product of micro-evolution, (which is a proven force in nature, we have seen it) because of shoes and not needing to chase prey on foot as much.
The appendix is a poor argument against creation because you are more susceptible to diseases without it, and we probably used to eat a lot of wild things that could've needed that extra push from the immune system and intestines. But that last bit is just my thought
For the argument of our eyes having blood vessels in the front whereas cephalopods have them in the back.. we live on land where the only thing we have to protect our eyes from the sun is the air it has to pass through, if those blood vessels were not there to stop the bulk of the days from hitting our retinas, we would go blind relatively quickly. You don't want a squids eyeball trust me.
The whale bones argument about then having vestigal old leg bones from then having used to walk on land, is debunked very quickly when you learn that those bones are there for muscles to connect to, and hold their massive whale cocks when theyre mating lol. They need those bones to have an anchor point for their reproductive system. Why that is still in that wiki idk bc that's a fact jack ;) lol
You could argue all day that the body has flaws, mine does, yours does, everyone pretty much does. But I don't see how that would take away from intelligent design. The video you just watched INSANE. Like how does all that work without any of those things having brains. It just does it. It's a machine. And the whole ATP stuff is just a drop in the infinite bucket of incredible things that work together. Watch videos on reproductive systems and on how the atmosphere works and magnetic fields and all that jazz, it's just not logical to think that all came from nothing from nowhere and just kinda happened.
Sorry if these ideas and stuff aren't well put together or organized I'm just kinda sitting in bed and typing on my phone but you know how that goes :)
@@bandrewsonp5379 Although I don’t believe in creationism, these type of things do question my understanding of evolutionary biology.
@@thatguyjohnny8235 God didn't create man in his likeness. Most probably, God is a collection of Subatomic particles. They created themselves in their own likeness at the beginning of the Universe. The rest is history.
4 billion years of planning, cooking, trying, fitting, building, molding, hacking, developing, and machining ... result is this tiny machine what drives EVERYTHING living on planet Earth.
Minus the viruses... which is fascinating!
The mitochondria is the powerhouse of the cell.
Absolutely LOVE this!
Body lore
Intelligent design at its best. Evolution cant explain a molecular machine like this, which is irreducible complex.
I had to leaf through scores of comments before I found this: it's the first thing that comes to my mind when I watch.
Ive learned parts of this but have never really seen it all in one place, honestly one of the coolest things ive seen in a while
Sorry for asking... but could you make a video let in us know how did you all manage to know all this... ? I mean how many years to figure this out? which tools you use ? techniques etc? Thanks
you should be proficient in cell theory in in under two years...to understand cell biology with respect to fully understanding cellular dynamics and fundamental biochemistry, 4 years... to become a molecular and Cellular Biologist, or other specialties like a Forensic Pathologist, Hematologist, Oncologists or Biochemist... you're looking at 8 year plus another 4+ years -- depending on the fellowship, and even then, it's ongoing -- forever leaning new things everyday
わかりやすい！
very intelligent design
Biology has no need for that hypothesis.
Evolutionists, do not fool yourselves into the gates to hell.
13 For You formed my inward parts; You covered me in my mother’s womb.
14 I will praise You, for I am fearfully and wonderfully made; Marvelous are Your works, And that my soul knows very well.
15 My frame was not hidden from You, When I was made in secret, And skillfully wrought in the lowest parts of the earth.
16 Your eyes saw my substance, being yet unformed. And in Your book they all were written, The days fashioned for me, When as yet there were none of them.
Psalms 139:13-16 NKJV
Looks awfully complex.... Would love to hear someone explain how this came to be through blind chance.
cink epric...they can’t, because it didn’t! 😉
Surely, an intelligent creator would make a much simpler, more efficient system. Seems much more likely for chance to build a complicated system
@@gadkinson poor design is not an argument for no design. In order to say something has poor design you would need to know the intention of the designer. A bicycle works great for getting you around town but not for taking you cross country. From your perspective, the bicycle evolved by chance as it is a poor choice for transporting long distances.
@The Senate I see no explanation of how these micro machines came about in your very astute reply.
I'd suggest looking into Chemical Evolution. Many basic components that cells use spontaneously self-assemble in the right conditions, literally popping into existence through "blind chance". What more, there are theories that life came from viruses that gained an ability to self-replicate, as viruses are VASTLY simpler than cells are. It's good food for thought.
Also, even if the odds of it happening through blind chance are one in a couple trillion (or much more), the Earth is massive, and had 100s of millions of years to "roll the dice". In fact, no matter the odds, the only reason we exist and can speculate about this is because it did happen, so postulating about the chances is kind of beside the point.
Wow! Ain’t no random process put THAT thing together, that’s for sure! God’d a genius! (Yea, yea argument from personal incredulity, God of the gaps, I can already feel these replies coming. But come on! How do you look at that and conclude that random events resulted in that instead of someone having engineered it?)
Wow...
Xenos are pretty clever. They created a self-regulation molecule size turbine to chain build a tiny spark of energy to power a little cell. That makes up our entire physical body.
I've seen these simulations before, but this was the FIRST to show how the F1 actually promotes the formation of the ADP/Pi ---ATP transition state. J.B.S. Haldane would be proud.
THE POWERHOUSE OF THE CELL IN ACTION
Beautifully created 👍
"The F-Zero complex is embedded in the membrane." Of course! It all makes sense now!
I was wondering why this kept showing up in my recommendations.