ATP & Respiration: Crash Course Biology #7

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  • Опубликовано: 11 мар 2012
  • In which Hank does some push-ups for science and describes the "economy" of cellular respiration and the various processes whereby our bodies create energy in the form of ATP.
    Special thanks go to Stafford Fitness (www.staffordfitness.net) for allowing us to shoot the gym scenes in their facilities.
    This video uses sounds from Freesound.org
    Table of Contents:
    1) Cellular Respiration 01:00
    2) Adenosine Triphosphate 01:29
    3) Glycolysis 4:13
    A) Pyruvate Molecules 5:00
    B) Anaerobic Respiration/Fermentation 5:33
    C) Aerobic Respiration 6:45
    4) Krebs Cycle 7:06
    A) Acetyl COA 7:38
    B) Oxaloacetic Acid 8:21
    C) Biolography: Hans Krebs 8:37
    D) NAD/FAD 9:48
    5) Electron Transport Chain 10:55
    6) Check the Math 12:33
    Crash Course is on Patreon! You can support us directly by signing up at / crashcourse
    Want to find Crash Course elsewhere on the internet?
    Facebook - / youtubecrashcourse
    Twitter - / thecrashcourse
    Instagram - / thecrashcourse
    CC Kids: / crashcoursekids

Комментарии • 6 тыс.

  • @JAM609
    @JAM609 5 лет назад +7312

    The hour long complicated version with finger puppets is literally what I need.

    • @ryan_s
      @ryan_s 4 года назад +182

      same i have ap bio.

    • @kodarpy
      @kodarpy 4 года назад +167

      Same, I have college Bio

    • @natalie5686
      @natalie5686 4 года назад +38

      Jana ElRifai frfr IB sad bro

    • @VG876
      @VG876 4 года назад +92

      I was reading this comment and was like “puppets”? Then halfway thru the video.. yes... I need the puppets too.. 😂

  • @departmentofanalytics1116
    @departmentofanalytics1116 6 лет назад +9554

    Since the animations are kinda confusing the numbers up, I recapped the transformation here:
    *Glycolysis*
    Glucose + 2 ATP >> 2 Pyruvates + Energy.
    This energy is used for making 4 ATP (net profit of 2 ATP) and 2 NADH from 2 ADP, 2 NAD+ and 2 hydrogen (probably H+).
    *Fermentation*
    Pyruvate >> Energy + Lactic Acid.
    *Krebs Cycle*
    2 Pyruvates + 2 O₂ >> 2 Acetyl Coenzyme A + 2 CO₂ + Energy.
    This energy is used to form 2 NADH from NAD+ and hydrogen.
    2 Acetyl Coenzyme A + 2 Oxaloacetic Acid >> 2 Citric Acid.
    2 Citric Acid + 4 O₂ >> 2 Oxaloacetic Acid + Energy + 4 CO₂.
    This energy is used to make 2 ATP, 6 NADH and 2 FADH₂.
    So after the Krebs Cycle we now have 10 NADH, 2 FADH₂ and 4 ATP (or 6 if you count the ATP spent in Glycolysis).
    *Electron Transport Chain*
    10 NADH >> Energy + 10 NAD+ + 10 Hydrogen.
    This energy is used to pump some protons out of the inner membrane of the mitochondria. They went back through the ATP synthase creating at most 3 ATP for each NADH, for a total of 30 ATP (at most).
    2 FADH₂ >> Energy + 2 FAD+ + 4 Hydrogen.
    This energy is also used to pump some protons. This creates, at most, 2 ATP each FADH₂, for a total of 4 ATP.
    _Conclusion:_
    _Total ATP created: 38 molecules, if the cell is very efficient._
    _2 ATP is spent in glycolysis so there would be at most 40 ATP that went through the steps._
    _10 NAD+ were used, and probably reused._
    _2 FAD+ were used, and also probably reused._
    _6 O₂ were used and they became 6 CO₂ in the Krebs Cycle._
    _2 Oxaloacetic Acid were used and reused._
    Hope this helps!

  • @anushabenny8586
    @anushabenny8586 5 лет назад +5183

    probably should've paid attention in class... questioning life choices

    • @yesenia4800
      @yesenia4800 4 года назад +491

      Anusha Benny When you pay attention but still don’t understand 😔😔😔

  • @Christian-dc1cy
    @Christian-dc1cy 4 года назад +1871

    Adenosine Triphosphate: **shoots off third phosphate group**
    Adenosine: "Die, Phosphate!"

  • @epic1tmk
    @epic1tmk 6 лет назад +2386

    I don't care what grade I'm in, I'll always resort to Crash Course to help me study for an exam

  • @Ljh4220
    @Ljh4220 9 лет назад +4541

    Cells are too complicated for their own good. Soon they will band together and become powerful enough to take over the wor-- oh wait.

    • @swaveboard5187
      @swaveboard5187 9 лет назад +33

      Vercingetorix 39 billion*

    • @KingOfShenanigan
      @KingOfShenanigan 9 лет назад +36

      MARK CHAN i think he or she was referring to humans, so it would only be about 20 thousand years ago.

    • @callum1029
      @callum1029 9 лет назад +8

      KingOfShenanigans Errrrm... both of you got that one wrong. About 200,000 - 1,000,000 years since the earliest known Homo Sapiens.

    • @CheckAlakaDingDong
      @CheckAlakaDingDong 9 лет назад +5

      Callum Baker i'm flammable

    • @charliehutch3533
      @charliehutch3533 9 лет назад +5

      KingOfShenanigans aaaaaaaaaah no. keep reading r-e-a-d-i-n-g...a study of present-day mitochondrial DNA, combined with evidence based on physical anthropology of archaic specimens. According to genetic and fossil evidence, archaic Homo sapiens evolved to anatomically modern humans solely in Africa, between 200,000 and 100,000 years ago,

  • @sophiamanzano2109
    @sophiamanzano2109 5 лет назад +1411

    I wish he was my bio teacher 🤧💀😂 he makes everything so fun and easy !!! Also who has an exam tomorrow?

    • @hamzaiftikhar6160
      @hamzaiftikhar6160 4 года назад +14

      Going to have science quiz tomorrow thats why i am here lol

    • @maryamalmehairi9537
      @maryamalmehairi9537 4 года назад +3

      Me

    • @Fatima-om5be
      @Fatima-om5be 4 года назад +7

      I have a quiz tmrw and I don’t understand anything lol

    • @ellakirkpatrick4895
      @ellakirkpatrick4895 4 года назад +2

      @PANDA GIRLS how did it go?

    • @Fatima-om5be
      @Fatima-om5be 4 года назад +7

      Ella Kirkpatrick it actually went good I didn’t expect that

  • @hooralaeenalshamsi500
    @hooralaeenalshamsi500 5 лет назад +6100

    Roses are red
    Violets are blue
    Stop reading the comments
    You have work to do

  • @GodOfStrategy
    @GodOfStrategy 8 лет назад +8480

    Anyone else zone out and have to re-watch this?

    • @matiasvega4191
      @matiasvega4191 8 лет назад +170

      +GodOfStrategy Totally, still a good video though

    • @GodOfStrategy
      @GodOfStrategy 8 лет назад +53

      For sure

    • @youthculture523
      @youthculture523 8 лет назад +150

      +GodOfStrategy Re watched probably 6 times now. It took me that long to completely understand lol

    • @matiasvega4191
      @matiasvega4191 8 лет назад +57

      It might easier for you to watch the crash course videos first and then try to find a handwritten tutorial for the topic. There is a really helpful user called Handwritten Tutorials

    • @snowflakefb6432
      @snowflakefb6432 8 лет назад +13

      +GodOfStrategy I saw different videos about that several times. Many in German (my
      primary language) and then some in English by Paul Anderson and this
      Chanel because I actually have to know all that stuff currently in
      English (year abroad). It really takes an awful looooong time to
      actually get all that stuff! So, yeah. I re-watched it several times.

  • @aim5105
    @aim5105 7 лет назад +1903

    Trying to learn an entire semester of Biology in one night 🙃

    • @bigbangsqueen
      @bigbangsqueen 7 лет назад +31

      me too :')

    • @fuckyourfuneral
      @fuckyourfuneral 6 лет назад +24

      Facts💀

    • @zo6052
      @zo6052 6 лет назад +39

      This is actually me this I hope u passed ur exams this is so memorable....

    • @712someone6
      @712someone6 6 лет назад +7

      Ai M u mean 13 minutes

    • @makaylas8914
      @makaylas8914 6 лет назад +9

      I'm trying to do two semesters... I'm definitely going to fail

  • @miriamosland5273
    @miriamosland5273 5 лет назад +2255

    This video made me cry. I understand nothing. Please help

    • @amymccrae1074
      @amymccrae1074 5 лет назад +108

      Sis I feel you

    • @catiegrace7957
      @catiegrace7957 5 лет назад +73

      I feel y’all 😂 I’m in the same boat

    • @cozmorules6983
      @cozmorules6983 5 лет назад +415

      so basically its complicated, a glucose (a simple suger) is cut up and bits and pieces make energized molecules such as NADH. These energized molecules shove protons (+H) to the other side of the mitocondrial membrane and whem they want to come back in they are squished together with a phospate and a ADP (adenesize DIphosphate) to essetially make ATP. hope this helps :>

    • @cozmorules6983
      @cozmorules6983 5 лет назад +21

      no problem :>

    • @Mergirl3196
      @Mergirl3196 5 лет назад +75

      idk if this will still help, but i totally recommend amoeba sisters, a biology youtube channel. i think it goes a bit slower, and doesn’t go as in depth, but gives a general outline of things

  • @granny4life975
    @granny4life975 6 лет назад +1209

    my brain is not excepting this knowledge

    • @MRWOOHOO1313
      @MRWOOHOO1313 5 лет назад +178

      ilakrnb your brain is not expecting the fact excepting is spelled accepting

    • @sciencemiddleschool1956
      @sciencemiddleschool1956 5 лет назад +68

      Break it down into small steps, one step at a time buddy. Review it several times. One step at a time! When you understand part 1, go to part 2. Never give up.

    • @cosmiccosmog3919
      @cosmiccosmog3919 4 года назад +6

      @@MRWOOHOO1313 wooosh

    • @evelynt2553
      @evelynt2553 4 года назад

      ilakrnb is that DEAN

    • @skinach
      @skinach 4 года назад +19

      @@cosmiccosmog3919 I don't think that's how the wooosh joke works. Michael is not ignoring the joke, he's just correcting ilakrnb's spelling.

  • @paulalobo1509
    @paulalobo1509 8 лет назад +772

    this was a whole chapter of my book in 13 min omg i love this

    • @YasmineEPangxx
      @YasmineEPangxx 8 лет назад +19

      +paula lobo ikr i have a bio test on this tomorrow and these videos are a lifesaver. meanwhile my textbook is like a bible- it's beautiful, it's lifesaving as well, but dang can it be complicated to understand.

    • @shaniyawarren6724
      @shaniyawarren6724 8 лет назад +11

      +Yasmine E. Pang my bio test is today and im watching this at 4:00 in the morning desperately trying to inprove my grades

    • @gracebaker4553
      @gracebaker4553 8 лет назад

      +paula lobo same i am writting a paper and the book did not cover this stuff

    • @paulalobo1509
      @paulalobo1509 8 лет назад +1

      Yasmine E. Pang i just foumd ez notes .put cambel biology and the chapter it helps alot

    • @paulalobo1509
      @paulalobo1509 8 лет назад +1

      Shaniya W use ez notes omg it helps

  • @cloncar101aj7
    @cloncar101aj7 6 лет назад +4042

    Ah the photosynthesis and cellular respiration unit of Biology. Good luck to everyone else suffering :')

  • @kamberosa
    @kamberosa 5 лет назад +595

    It’s been 7 years and I’m gonna need that enzyme puppet show now... 😅

  • @user-kg6bv5fk3w
    @user-kg6bv5fk3w 5 лет назад +510

    60% of comments: How people are cramming for finals
    20% of comments: People asking for prayers
    15% of comments: Both of the above combined
    5% or comments: Other

    • @mercymcglade3351
      @mercymcglade3351 5 лет назад +3

      CobraHawk 140% make it equal 100% lol

    • @sus3309
      @sus3309 4 года назад +3

      You forgot some of us don’t understand a single thing

  • @gracenason2308
    @gracenason2308 6 лет назад +2796

    I’m gonna ace this test, ready guys: the miTOCHONDRIA IS THE POWERHOUSE OF THE CELL

    • @kismetflash0429
      @kismetflash0429 5 лет назад +7

      YESSSSSS

    • @nadine-sm3po
      @nadine-sm3po 5 лет назад +129

      that is literally all i know about biology

    • @sleepy1604
      @sleepy1604 5 лет назад +30

      Whoa careful with the controversy lol

    • @nadine-sm3po
      @nadine-sm3po 5 лет назад +5

      Umair oh ma god that’s why i got it wrong on the test 💀💀💀💀

    • @A.K.00
      @A.K.00 5 лет назад +1

      @daddy nadine this is literally all i know about life

  • @tiggytheimpaler5483
    @tiggytheimpaler5483 6 лет назад +4504

    hah, all these people in the comments mentioning that they are watching this the night before their exam
    how about watching this on the way to class? beat that plebs!

    • @seancreamer3349
      @seancreamer3349 6 лет назад +293

      What about watching it during class?
      Beat that

    • @boredom3398
      @boredom3398 5 лет назад +142

      Procrastination at its finest

    • @xchwekfb
      @xchwekfb 5 лет назад +176

      Pfff peasant i watched it during the exam

    • @Ligierthegreensun
      @Ligierthegreensun 5 лет назад +16

      Watching it before I ever take orgo

    • @lijemayne4287
      @lijemayne4287 5 лет назад +6

      😂😂😂

  • @coleman3256
    @coleman3256 5 лет назад +151

    Glycolysis:
    Takes place in Cytoplasm is Anaerobic
    Breaks down Glucose into 2 pyruvate molecules, 2 NADH, and 4 atp
    Requires 2 ATP investment so a net gain of 2 ATP
    Krebs Cycle
    Aerobic, happens across the inner membrane of mitochondria
    One of the pyruvates is oxidized (combined with oxygen) and leaves the cell as CO2
    What's left is a two-carbon compound called acetyl-Coenzyme A (Acetyl CoA)
    Then another NAD+ comes along and picks up hydrogen becoming NADH
    Enzymes bring together a phosphate w/ a ADP to create another ATP molecule for each pyruvate (2 ATP)
    Enzymes also join Acetyl CoA w/ Oxaloacetic Acid to produce citric acid
    The Citric acid is oxidized, cutting off carbons to prodcue oxaloacetic acid, that's why it’s a cycle
    Carbons are exhaled by the cell
    Each time carbon is removed from the citric acid it releases energy in the form of NAD+ and FAD
    NAD+ and FAD are electron carriers that pick up Hydrogen protons to energize the electrons
    Each pyruvate yields 3 NADHs and 2FADH2s per cycle and there are two pyruvates from 1 glucose
    Produces: 2 NADH
    Electron Transport Chain (ETC)
    Electrons in all the NADH and FADH2 provide the energy to pump Hydrogen ions across the inner membrane of mitochondria (active transport) creating a Concentration Gradient
    Because of the Gradient, the H protons want to cross back to the other side of the membra=ane, this forces them through a protein channel called the ATP synthase which uses the movement of the protons to spin and generate ATP
    Produces: 34 ATP (energy of each electron is producing about 3 ATP each
    Lactic Acid Fermentation:
    Anaerobic-only used when there is a lack of oxygen
    Frees up some NAD+ which create Lactic Acid Buildup
    Can't make much ATP
    Your Welcome- u should sub

  • @beatrisefranzhearts4649
    @beatrisefranzhearts4649 5 лет назад +246

    Everyone's saying "My exam's tomorrow" and I'm like "My exam starts in an hour" ;-;

  • @TheChillinPenguin
    @TheChillinPenguin 9 лет назад +171

    I got 94% in my biology christmas exam!! I want Hank to be proud of me more than I want my own parents to be

    • @The112Windows
      @The112Windows 9 лет назад +14

      I am sure he is proud of you.

    • @FROPDESAI
      @FROPDESAI 9 лет назад +2

      Alison Good. Why would anyone even dislike these videos?

    • @antonior1908
      @antonior1908 9 лет назад

      Alison his wife must be proud of you as well. Did you see his ring on his ring finger?

    • @user-yh1kq9ch9q
      @user-yh1kq9ch9q 9 лет назад +2

      Alison Seems like another "by product" of Hank's videos.

    • @christinea6372
      @christinea6372 9 лет назад +1

      Antonio R Um...do you mean "The Katherine"? She was the woman standing next to him in the "In Da Club" video...though you might be right. I think she has a degree in science.

  • @Zosio
    @Zosio 8 лет назад +141

    To everybody out there struggling with this: don't give up! Do not underestimate how much it helps to slowly watch the video bit by bit, over and over. I had to do this quite a few times, but I feel like I've finally got the hang of this. You can do it!
    And thanks to Hank and the team!

  • @matthewdylan
    @matthewdylan 4 года назад +71

    I've been going to a 2 hour lecture everyday for a week and picked up nothing about Cellular Respiration. Crash course literally taught me and helped me understand this in 13 minutes!

  • @noaefron2105
    @noaefron2105 4 года назад +25

    I used to watch these videos all the time in high school and they got me through AP bio my sophomore year... I took a few years off after high school (so its been a while), and now that I'm in university majoring in biology, crash course is once again saving my life - thank you!!

  • @kaylasea8098
    @kaylasea8098 6 лет назад +6940

    Who else is cramming for a college bio exam?

    • @majedal-bean3015
      @majedal-bean3015 5 лет назад +410

      iam studying for my ap bio class as a freshman in highschool

    • @budgetloki
      @budgetloki 5 лет назад +63

      i legit have an on line exam right now and a essay to right on this

    • @animelovinggamer5712
      @animelovinggamer5712 5 лет назад +133

      Grade 11 Bio

    • @yussuf.95
      @yussuf.95 5 лет назад +3

      😭

    • @ernestovazquez9129
      @ernestovazquez9129 5 лет назад +150

      Its currently 4:29 am, my test is at 11:00 and lets just say I was doing extra credit for another exam I have later today that now im finally studying for this exam and I fear it might be too late, please pray for me.😅😴

  • @allanochoa4826
    @allanochoa4826 9 лет назад +420

    if you're watching this,
    it's too late.

    • @LittleMonster2410
      @LittleMonster2410 9 лет назад +11

      Allan Ochoa i still dont understand shit after watching it...

    • @allanochoa4826
      @allanochoa4826 9 лет назад +4

      ask me questions, I took a test on this and aced it btw,

    • @WhatdidIsayagain
      @WhatdidIsayagain 9 лет назад

      Allan Ochoa I know but let me be in denial D:

    • @13zomi
      @13zomi 9 лет назад +7

      I know. I have an AP Bio exam in 2 weeks so I need to get this crap down but even after watching Crash Course which I usually understand, I still feel like I'm at square one :/

    • @veganchris1933
      @veganchris1933 9 лет назад

      We're all so fucked :(

  • @gracie6337
    @gracie6337 9 месяцев назад +12

    Even after 11 years, this video is still used by a student who is cramming the night before… it’s me. I’m the student

  • @moayadallahamm8176
    @moayadallahamm8176 4 года назад +153

    the biology community has the funniest students and this comment section is proof

  • @amandabivens247
    @amandabivens247 6 лет назад +376

    I watch all of the crash course biology videos while studying for my biology class. While I like my instructor, he is not very descriptive about the biological processes themselves. I am always lost in class, and then have to come watch videos to see the processes, and understand. I can memorize definitions all day, but I have to see stuff in action to be able to truly understand it. Thanks guys! You are my heroes!

    • @sleepy1604
      @sleepy1604 5 лет назад +3

      Amanda Bivens mines scatter brained and I can’t keep myself with her cause she’s all over the dang place

  • @fusianducks
    @fusianducks 8 лет назад +2336

    Bio exam tomorrow pray for me

  • @xXbussydestroyerXx
    @xXbussydestroyerXx 5 лет назад +142

    It's the first week, they said...
    We won't give you any complex homework, they said...

  • @timetime5689
    @timetime5689 5 лет назад +518

    IM ONLY A HIGH SCHOOL FRESHMAN!! WHY DO THINGS HAVE TO BE SO COMPLICATED!!

    • @Pussyypirate
      @Pussyypirate 5 лет назад +35

      Same I have a quiz tm! And my teacher sucks so I have learned nothing and we’re already in second quarter!!

    • @anshulwadhwani5534
      @anshulwadhwani5534 5 лет назад +7

      same here ikr

    • @ameliemena9725
      @ameliemena9725 5 лет назад +2

      Mood

    • @Ghosth0e
      @Ghosth0e 5 лет назад +52

      its wild cause if you choose to attend college you'll be faced with these same concepts again lol its crazy how you're probably 14-15 learning the concepts im relearning as a 19 year old lol

    • @noice9782
      @noice9782 5 лет назад +17

      when u learn more watching crash course vids than paying attention in class

  • @W3AFed
    @W3AFed 7 лет назад +423

    Man, I wish Hank was my Biology teacher. My teachers made it so complicated when they were talking about ATP production in the ETC, but now I totally get it!

    • @GothicElf68
      @GothicElf68 7 лет назад +7

      He has a psychology crash course series as well, that is just as good. Hank is awesome.

    • @thedysfunctionalpsychos5342
      @thedysfunctionalpsychos5342 7 лет назад +1

      Stuart? At least they try and teach😂 mine certainly doesnt

    • @kottayami5391
      @kottayami5391 7 лет назад +6

      In video form,it's way easier to teach.Including animations for visual aid.
      But true,he seems advanced at Science.

    • @callmecookie6945
      @callmecookie6945 7 лет назад +1

      i know right I dont really understand it when my teacher explains but when I look at these videos a lightbulb goes off😂

    • @natedole8276
      @natedole8276 7 лет назад +3

      it helps if you can rewind...

  • @COWHATE
    @COWHATE 10 лет назад +41

    This 13 minute video summed up my 50 minute long Bio Process class about a 3 weeks ago.....Gotta love the internet.

  • @higuyz7872
    @higuyz7872 4 года назад +152

    "CHINESE YEN". :-D
    -Well he teaches bio

  • @zachsmith158
    @zachsmith158 5 лет назад +27

    On behalf of every IB Biology student around the world, I just wanna say thank you 🙏

  • @kingjonstarkgeryan8573
    @kingjonstarkgeryan8573 7 лет назад +1743

    College Bio Exam tomorrow. Please pray for me.

    • @kingjonstarkgeryan8573
      @kingjonstarkgeryan8573 7 лет назад +6

      Pavan Bopara Dues Vult Heathan!!!

    • @kingjonstarkgeryan8573
      @kingjonstarkgeryan8573 7 лет назад +1

      Pavan Bopara It was a Crusader Kings 2 joke.

    • @dylanoliver4861
      @dylanoliver4861 7 лет назад +40

      damn man i'm a freshman in highschool and i have to do all of this

    • @Kquhai
      @Kquhai 7 лет назад +13

      Bro, Same, I've got midterms next week and a bio test tomorrow. I have to go here cause my teacher is just confusing me.

    • @kristenwhite5153
      @kristenwhite5153 7 лет назад +7

      I have a midterm tomorrow

  • @evaa6909
    @evaa6909 7 лет назад +52

    You are currently my hero. My textbook is terribly written and it only took 13 mins to go from struggling to understand even one cycle to 98% on my test. What would I do without you Hank.

  • @margaretthym8234
    @margaretthym8234 4 года назад +5

    It's 2020 and my "Science for Teachers" instructor assigned this video and I am a happy nerdfighter for that! Will continue to use these videos in my class as a student and I'll use crash course kids when I have my own classroom one day! :D

  • @noelleveronica9589
    @noelleveronica9589 6 лет назад +156

    CRAMMING THE NIGHT BEFORE MY BIO EXAM, WHO'S WITH ME?!?!

    • @nate9755
      @nate9755 4 года назад +1

      I am Right now!!!!!

    • @joshuathompson566
      @joshuathompson566 4 года назад +1

      Gang

    • @jessipl
      @jessipl 4 года назад

      All I do to prepare for bio tests and now this exam is rewatch all of Hank's videos and make notes on them.

  • @weendylry5598
    @weendylry5598 7 лет назад +757

    good luck to all of you that are going to sit for Biology exam :D god bless

    • @crystalinexiii2638
      @crystalinexiii2638 7 лет назад +4

      thanks. appreciated

    • @mariacillan9668
      @mariacillan9668 7 лет назад +5

      Bio exam is tomorrow, and thanks ^_^

    • @kaitsune00
      @kaitsune00 7 лет назад +2

      Wenndey Luvette mines tomorrow!😭 good luck to others too

    • @weendylry5598
      @weendylry5598 7 лет назад +3

      Lash Clash i passed with flying colors 😘

    • @anselally4408
      @anselally4408 7 лет назад +1

      you're pretty, marry me

  • @AsiaChan
    @AsiaChan 8 лет назад +47

    thank you hank green, you don't know how many lives you have saved

  • @esther9210
    @esther9210 5 лет назад +268

    Can we switch brains for my test?😫

    • @msjsss1102
      @msjsss1102 5 лет назад +12

      Not possible, I thought ur learning bio. U should know

    • @ompal1003
      @ompal1003 5 лет назад +9

      @@msjsss1102 lmao

    • @jamarimcfarlane4844
      @jamarimcfarlane4844 5 лет назад

      @@msjsss1102 if u take out your brain, will u die?

    • @PersimmonHurmo
      @PersimmonHurmo 4 года назад +3

      @@jamarimcfarlane4844 yes, very dead

    • @TheMajesticKnight
      @TheMajesticKnight 4 года назад +2

      @@msjsss1102 lmaoooo

  • @tiffanyhuynh1890
    @tiffanyhuynh1890 4 года назад +6

    Thanks for this great video!
    Some other helpful things to note that were not explicitly stated in the video:
    -The Krebs Cycle occurs in the inside of the inner mitochondrial membrane AKA in the mitochondrial matrix.
    -Another name for the Krebs Cycle/Citric Acid Cycle is the Tricarboxylic Acid (TCA) Cycle, so if you ever hear those terms, know that they all refer to the same process.
    -Cellular respiration occurs not only in animal cells but also in plant cells.

  • @Jazzerbean
    @Jazzerbean 7 лет назад +68

    This is probably the most complex topic in Cell Biology. It's a little difficult to keep track of what's being broken down, what and how much is produced and most of all, how is it all produced. Thanks for the visuals and keeping this topic entertaining.

    • @birdies8397
      @birdies8397 6 лет назад +4

      Jazzerlat45 It really does help if you just write out the whole mechanism. It really helps you understand what's going on and what's produced (and the names of the enzymes and products being created). I think oversimplifying such a complex process like this does more harm than good: it just leads to confusion. It really makes a lot of sense if you just draw the whole thing out, step by step, molecule by molecule.

  • @dantesprull1832
    @dantesprull1832 9 лет назад +83

    Despite all of the hate left on your comment log, I thought this was a very educational and entertaining explanation of respiration. The visual displays were awesome, The sound effects kept me amused and the fun facts were note worthy. I hope to see many more videos from Hank and Crash Course

    • @eontami929
      @eontami929 9 лет назад +16

      Dante Sprull I WAS THINKING THE SAME THING! so much hate out there. This is made to coincide with your education, not replace it.

  • @juliagipson6129
    @juliagipson6129 4 года назад +36

    Having a panic attack from my bio course breezing through this and moving on in 45 min.
    With attention and learning issues, I must work 6x as hard to understand simple concepts.
    Your program has really helped me and others like myself to stay afloat.
    Thank you sooo very much!!

  • @lulazeta8965
    @lulazeta8965 Год назад

    BEST WAY TO EXPLAIN A COMPLICATED PROCESS. MOST VIDEOS DON'T ACHIEVE THE GOAL. CONGRATULATIONS "CRASH COURSE"!!! Graphics, Pauses, descriptions..excellent!!

  • @marktuan9298
    @marktuan9298 8 лет назад +932

    guys please pray for me to pass the test. I dont want to dissappoint my parent. wish me luck

  • @tgrey1885
    @tgrey1885 8 лет назад +332

    Bio final tomorrow...pray for me please.

    • @MidnightOpal
      @MidnightOpal 8 лет назад

      I wish you all the best!

    • @MidnightOpal
      @MidnightOpal 8 лет назад +3

      My finals aren't until after break, which is terribly challenging after vacationing for a month.

    • @tgrey1885
      @tgrey1885 8 лет назад +9

      I got a 96 on my honors bio final. Yay!!!!! Good luck on all your finals everyone.

    • @GoombaJMR
      @GoombaJMR 8 лет назад +2

      +T Grey Same here. Omg

    • @tgrey1885
      @tgrey1885 8 лет назад +1

      Haha twins! :)

  • @themaizfamily5074
    @themaizfamily5074 6 лет назад +3

    studying for my personal trainer certification it's been so much easier with your videos (specially bc english is not my first language and sometimes I don't get anything from the books 😂) THANK YOU SO MUCH! I love your way to explain and all the colorful graphics!!!

  • @wishingb5859
    @wishingb5859 5 лет назад +3

    You did a great job!
    I have been watching a lot of music videos on the Cell and Cell respiration and your crash course added a whole lot of little tidbits. I didn't know that glycolysis took place in the cytoplasm. I mentally was in the Mitochondria and I had learned through the songs that glycolysis didn't need oxygen, but I don't remember them saying that the Kreb's Cycle and Electron Transport Chain did. I also loved the three kids who don't get along on the same seat of the bus analogy. That actually did happen on the school bus when I was young and then one gets off and it was such a relief. Yes, I learned a lot.

  • @AlexanderWung
    @AlexanderWung 9 лет назад +36

    Can I just add something that confused me for a while and only recently understood it. Glucose does not "produce" 32 ATP molecules. It provides the hydrogen ions to create a potential difference between the membrane which can then be used to synthesise ADP into ATP. The molecules of the ADP, ATP, and the phosphate group that breaks off/attaches on to ATP/ADP circulate around the whole system, again, they aren't "produced" by glucose alone.
    I was struggling over this concept for over a month before I had a deeper look into this, and thought this might benefit another person who came to this video looking for help.

    • @notadog1701
      @notadog1701 9 лет назад +6

      Alexander Wung Actually, Glucose provides the electrons required for the ETC to create the proton gradient.

    • @AccuphaseMan
      @AccuphaseMan 8 лет назад +1

      +Alexander Wung i have a friend called alexander wong

    • @duser
      @duser 8 лет назад +8

      +Alexander Wung You can think of it as a power plant (brace for some long physics and more chemistry). Lets take a coal plant (ignore the environment for now or lets just say that proper measures have been placed to make sure the environment gets left alone)
      The glucose is the raw material in the reaction like coal. Its molecules contain all the energy in the form of chemical energy. During glycolysis, energy is needed to break the bonds in the glucose molecule (like activation energy). This is why we need the initial supply of ATP, to provide the activation energy. This is like heating the coal up in order for them to burn. Once the bonds are broken, the formation of new bonds releases more energy such as the formation of pyruvate molecules and 4 ATP molecules in glycolysis.
      Next, the energy that remains in the pyruvate molecules is extracted. In the Kalvin cycle the energy remaining in the pyruvate is extracted but is not directly stored in the form of chemical energy in ATP yet. It is instead stored in the form of chemical energy the molecules NADH and FADH2. Back in the power plant, this is like the coals burning and releasing energy into the water around them. The energy that was stored in the coal is not converted into electricity directly, but converted into heat energy in the water, which is then utilized to get the electrical energy.
      Finally, we get to the electron transport chain. The energy of the NADH and FADH2 is converted into potential energy in the proton gradient (hydrogen ions concentration gradient). This new form of energy is then used to synthesize ATP as the protons flow down their gradient and activate ATP synthesase. Back in the coal plant, the heat energy is used to turn the turbine blade, the heat energy is converted into kinetic energy. the turning blade then produces energy.
      quit simply, glucose doesnt form ATP, but the energy stored in glucose is transferred to ATP through cellular respiration. Energy is flowing from glucose to other molecules and finally ATP.

    • @bhargavagowda8434
      @bhargavagowda8434 8 лет назад

      +Alexander Wung Correct me if I'm wrong, but in glycolysis and krebs cycle, molecules derived from glucose ie. pyruvates and acetyl coA are used to make ATP. So glucose makes some ATPs while the rest are made from the potential difference. Also I'm pretty sure that anaerobic bacteria get most of their ATP from glycolysis in which glucose is broken up to directly produce ATP.

  • @sinningcieje
    @sinningcieje 7 лет назад +545

    So everyone is here because we all just reached respiration and photosynthesis in our bio class, right?

  • @oliviabaer7276
    @oliviabaer7276 4 года назад +10

    quick salute for this man who is single-handedly getting me through AP Bio *heart eyes*

  • @tharealgavgav8306
    @tharealgavgav8306 7 месяцев назад +5

    senior undergrad pre-med major here... still using CrashCourse

  • @katefirestone7998
    @katefirestone7998 7 лет назад +118

    I wish they had like on line test after every episode to help you understand it even more

    • @TheLugiaSong
      @TheLugiaSong 6 лет назад +7

      Well there's always past papers + mark schemes. Going through papers is great revision I think :)

  • @dulcer4734
    @dulcer4734 8 лет назад +31

    The comments are just all pour souls studying a minute before the test. lol same af

  • @flagshipbuilds
    @flagshipbuilds 4 года назад +2

    I remember when this channel first started and now am seeing a video for an assignment! Good for you Crash Course!

  • @theterminalstupidityvariet1629
    @theterminalstupidityvariet1629 4 года назад +62

    Ah, midterms. The less terrifying finals

    • @isabellabennici2264
      @isabellabennici2264 4 года назад +3

      I have those next week and I don’t get this at all🥺

  • @andeedawn5389
    @andeedawn5389 7 лет назад +22

    Hank talking abt the cellular respiration in 13 mins. made me understand WAY BETTER than my teacher's lecture for 50 freaking minutes

  • @zachary6281
    @zachary6281 8 лет назад +100

    Night before finals, eating cookies and drinking hot chocolate, for a last minute review! This is the college life.

    • @WeAreObject
      @WeAreObject 8 лет назад

      Same lol

    • @TheSoHysterical
      @TheSoHysterical 8 лет назад

      +Zachary Goodrode But this is a high school level lesson?

    • @zachary6281
      @zachary6281 8 лет назад

      +So Hysterical Not necessarily. It's got some college level bits. Not doctorate level, but it served its purpose teamed with other vids.
      Cheers.

    • @TheSoHysterical
      @TheSoHysterical 8 лет назад +1

      Hmm.. You learn something new everyday haha

    • @amazonwarrior4743
      @amazonwarrior4743 7 лет назад

      that sounds amazing!!

  • @makibunn
    @makibunn 4 года назад +17

    MY AP TEST IS IN TEN MINUTES I DON'T HAVE TIME FOR THE JOKES AHFSABFDSBJFBFJSJ WATCHING AT 2X SPEED

  • @jumisjam
    @jumisjam 5 лет назад +164

    Im a college student and watching this like 10 mins before my midterm 😅😅

  • @Sydvicious_studios
    @Sydvicious_studios 7 лет назад +750

    Me: watches video night before test in hopes of understanding
    Also me: wtf is he even saying
    (No offense to your video I'm just an idiot)

    • @hannahjihyun
      @hannahjihyun 7 лет назад +1

      HellNaw ToTheNawNawNaw me

    • @lucyedward1163
      @lucyedward1163 7 лет назад +12

      HellNaw ToTheNawNawNaw I have a bio exam in less than 12 hours

    • @ylam4832
      @ylam4832 7 лет назад +1

      FanGirl ASMRandMORE literally me

    • @satishbhai3322
      @satishbhai3322 7 лет назад +1

      Y Man and 1girl group sex hd movie Jacky sheriff court on on the

    • @little-furina
      @little-furina 7 лет назад +14

      Better than me I have my test in two hours and am scrambling to figure this out...

  • @Sammyblackout
    @Sammyblackout 7 лет назад +299

    Who needs to go to lectures when I have a book and this?

    • @MacMac548
      @MacMac548 7 лет назад +1

      Samantha Yarnell lol exactly

    • @miguelb2421
      @miguelb2421 7 лет назад

      ?

    • @MacMac548
      @MacMac548 7 лет назад +1

      Miguel B yo can u not

    • @nomdeplume1358
      @nomdeplume1358 7 лет назад

      +Macky Schmit Are you going to sit and there and do nothing or are you going to put him in his place??

    • @luay110
      @luay110 7 лет назад

      +Miguel B u r a pervert

  • @brandonjohnson5182
    @brandonjohnson5182 4 года назад +23

    What youtube videos does this guy watch to get ready for HIS presentations?

  • @EmmaGrant-ye1xh
    @EmmaGrant-ye1xh 5 месяцев назад +3

    This video has made me feel more ready for my bio test tmr

  • @wonjaejang8975
    @wonjaejang8975 10 лет назад +38

    great studying is being done with this for bio midterms. THANKS

  • @madeleinedeardorff
    @madeleinedeardorff 9 лет назад +34

    Who's cramming for the AP bio exam Monday!!!!!

  • @ypam5576
    @ypam5576 6 лет назад

    Thank you for making that easy to watch and learn from AND entertaining at the same time. Much appreciated!!

  • @warriorcatskid003
    @warriorcatskid003 5 лет назад +1

    I just found out CC did a bio series! This is gonna be so helpful! Y’all are already basically teaching me psych!

  • @juliawiseman4102
    @juliawiseman4102 7 лет назад +4

    Hank Green is my favorite crash course teacher. Thank you for helping me become more confident in my psychology and science courses for nursing school. I'm a huge fan! You're the best, Mr. Green.

  • @rachelk.6918
    @rachelk.6918 7 лет назад +522

    Raise your hand if you're cramming for an AP test!

  • @warrenchampeon3832
    @warrenchampeon3832 7 месяцев назад +5

    This explanation is better then my bio text book lol

  • @stephvarchia2723
    @stephvarchia2723 4 года назад +29

    Btw Yen is Japanese currency and Yuan is chinese currency

  • @onthejon5326
    @onthejon5326 7 лет назад +54

    Crash Course:
    The best place to go to when you haven't studied for months

  • @elainecartermusic
    @elainecartermusic 10 лет назад +13

    My biology exam is tomorrow and I know everything now because of this video. I have this weird way of memorising things that interest me or its so visual that it stays in my mind. That is why I'm sure I will do well tomorrow. Great video! Crashcourse is the best way to study! Thanks a lot

    • @Toyon95
      @Toyon95 10 лет назад +3

      * *Le jealousy* *

  • @jessicasotkovsky4904
    @jessicasotkovsky4904 4 года назад +2

    thank you for helping me understand this concept! I watched it right before a final and it really helped.

  • @Bethers817
    @Bethers817 5 лет назад

    Definitely helpful. I’m understanding the process more than just from class lecture but will definitely have to watch it another time or two. Entertaining as well.

  • @thelegendaryluxray6088
    @thelegendaryluxray6088 8 лет назад +89

    Wish me luck on my test (tuesday). I'm gonna need it!!!

  • @bianca12727
    @bianca12727 8 лет назад +76

    This video made me realise I need to learn chemistry.

    • @LucaPed94
      @LucaPed94 8 лет назад +5

      LOL i said the same i think ill start with crash course chemistry

    • @Bobbylim323
      @Bobbylim323 8 лет назад +16

      This video is too simplified for my test 😭the intermediate names are pure cancer

    • @cindybabii
      @cindybabii 6 лет назад

      DEADASS

  • @shayladampier7740
    @shayladampier7740 5 лет назад +10

    I’ve learned more in this video that I have in a month and a half with my bio teacher explaining it over again. Thank you!

  • @lydia6613
    @lydia6613 4 года назад +9

    For those who are wondering, a phosphoglucoisomerase is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis.

  • @moonbunniee6050
    @moonbunniee6050 8 лет назад +152

    Actually it's *Japanese Yen not Chinese. China uses RMB

    • @ruoyicao1747
      @ruoyicao1747 8 лет назад

      +moon bunniee LoL

    • @laurapattison9929
      @laurapattison9929 8 лет назад +21

      +moon bunniee I think he's thinking of Chinese yuan and just mispronouncing it slightly by not making the 'oo' sound.
      Team Hank!!
      ...Ahem

    • @yuuka7856
      @yuuka7856 8 лет назад

      +moon bunniee Lmao, he really does say "Chinese Yen", honest to god.

    • @sophieyates3645
      @sophieyates3645 8 лет назад +1

      +moon bunniee stop trying to protect him guys. Just accept that he made a mistake and that's fine. I live in japan and it's definitely JAPANESE YEN.

    • @notfound9491
      @notfound9491 8 лет назад

      +Jasmin Castilla i dont care

  • @xxfarleyjdxx
    @xxfarleyjdxx 7 лет назад +17

    You've explained this better in 13 minutes than my bio professor did in 3 hours. This is going to help me with my exam in the morning.

  • @sharonkende4774
    @sharonkende4774 4 года назад

    This is so much easier to follow than earlier videos. Thanks, Hank

  • @mjr8456
    @mjr8456 5 лет назад

    i love the way you are reading the content, thank for video editor, you used ATP to cut & join the video to educate me. Good staff.

  • @missred2395
    @missred2395 8 лет назад +310

    Didn't expect cramming for my AP test to be so funny.

  • @tomisoetan9061
    @tomisoetan9061 8 лет назад +92

    I still love you asapscience, but, I've found someone else... what we had together was special, in Grade 9 i nearly learnt the periodic table because of you! but crash course, well he makes me feel so smart, so ready for any quiz. I would always love you, and cherish the time we had together and maybe one day we'll get back together... I'm still going to spend time with you but I think we should see other people. I'll always love you asapscience.

    • @tadimpsnola
      @tadimpsnola 8 лет назад +10

      This kind of made me sad .. And reminded me of other emotions

    • @David-xw2sy
      @David-xw2sy 8 лет назад +5

      +tatiana jacques Awww, it was just a Biology reference. No need for feelings in science!

    • @user-xx5nk1wv1e
      @user-xx5nk1wv1e 8 лет назад

      Lol, ASAPscience will always be my first love too XD What grade are you in now? I'm in 12th

  • @_pi6063
    @_pi6063 Год назад +1

    This ABSOLUTELY HELPED!!. I soooo appreciate these courses soo much.

  • @Disco.Wizard
    @Disco.Wizard 4 года назад

    Hank you are awesome, learning a lot more here than I ever did in school

  • @InnanetSlatt
    @InnanetSlatt 10 лет назад +79

    Who the fuck dislikes this video? It's both interesting and educational.

    • @HarunDanyal
      @HarunDanyal 10 лет назад +11

      Why even worry? You benefited from it, but not everyone has to.

    • @neohenry8292
      @neohenry8292 10 лет назад +17

      I would say some creationists, but I'm being too bias there.

    • @krishanbansalphotos
      @krishanbansalphotos 10 лет назад +11

      vverewolfchick Not everyone hates it, just people who don't like learning.

    • @lmTheDudeMan
      @lmTheDudeMan 10 лет назад

      or people who'd rather watch real lecture instead of wasting time going completely off the topic by some weirdo :)

    • @AdventuresOfMinty
      @AdventuresOfMinty 10 лет назад +8

      lmTheDudeMan Well this video isn't a Lecture but more of a review and crash course on the topic. If this was a lecture, it'd be typically 30 minutes to an hour long for obvious reasons.

  • @Matejamakeup
    @Matejamakeup 8 лет назад +48

    lol when you're cramming for midterms the night before @ME

    • @nomorepartiezz
      @nomorepartiezz 8 лет назад

      +Mateja me 2

    • @Hard2theXcore
      @Hard2theXcore 8 лет назад

      +Mateja And now here /I/ am a few months later cramming for finals

  • @aryansaeedi7618
    @aryansaeedi7618 5 лет назад +1

    Oh my God you are amazing. I am obsessed with your teaching thank you so much. You make it so easy to learn.

  • @alexandramcginnis559
    @alexandramcginnis559 4 года назад +4

    Thanks for the help. This and Photosynthesis are the two things I need to get figure out before the exam tomowrow

  • @Bettyisbroke
    @Bettyisbroke 9 лет назад +79

    i just dont .. i cant.. i dont understand ... IDONTUNDERSTAND *cries*

  • @moriahsun
    @moriahsun 7 лет назад +50

    Your show is absolutely amazing, thank you for being the only reason that I will pass my test tomorrow. Actually Gods a reason too.

  • @somethingsomething2541
    @somethingsomething2541 4 года назад +7

    Apparently after reading comments... I realised that you guys are being taught this stuff in collage.... And here is me...in my country we study this in school.

  • @abdullahosaid7978
    @abdullahosaid7978 7 месяцев назад +7

    00:00 Cellular respiration is how we derive energy from glucose.
    01:37 ATP is the currency of biological energy
    03:16 ATP is minted through cellular respiration
    04:44 Glycolysis generates 2 ATPs and 2 NADH
    06:30 Anaerobic respiration leads to lactic acid build-up in muscles
    08:13 Enzymes in the Krebs Cycle create ATP and CO2 through a complex cycle.
    10:09 B vitamins Niacin and Riboflavin hold high energy electrons for later use in the Electron Transport Chain
    11:44 Animal cells make ATP through cellular respiration