Parkinson's Disease (Shaking Palsy) - Clinical Presentation and Pathophysiology

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  • Опубликовано: 18 ноя 2024

Комментарии • 372

  • @prem5864
    @prem5864 2 года назад +35

    I am a doctor and I can say , this is by far the best pathophysiology explaination I have heard .

  • @lapharmacie98
    @lapharmacie98 4 года назад +216

    I can’t believe it, every single topic in physiology and patho I’ve ever needed some help with Armando has a video on it. What a legend

    • @lightblue3747
      @lightblue3747 3 года назад +2

      Yeah!! He has been helping me throughout my med school! 🥰🥰❤️❤️

    • @aribabatony4035
      @aribabatony4035 3 года назад +1

      Thanks you DR Rorpopor Herbal on RUclips for curing my herpes totally God bless you DR Rorpopor Herbal on RUclips contact for any candy of sickness.....💯

    • @adrenaline9182
      @adrenaline9182 3 года назад +1

      You can help me out? Though

    • @aribabatony4035
      @aribabatony4035 3 года назад

      @@adrenaline9182 ruclips.net/channel/UCkZwKW6qES4dXDWzb0YQErA

    • @Mosinee565
      @Mosinee565 2 года назад +1

      👏👏

  • @barbarabrennand7016
    @barbarabrennand7016 4 года назад +4

    I studied neuropsychology in my work with learning disabilities. This is the best information I have seen to explain Parkinson's on a neural level.
    thank you so much for this info.

  • @andresbadilla3220
    @andresbadilla3220 2 года назад +20

    You did this 6 years ago, and here I am, getting it clear. You are a blessing.

  • @MaitsaaRihhadatul
    @MaitsaaRihhadatul 4 года назад +1

    The most clear explanation of Parkinson disease pathophysiology in whole RUclips ❤️

  • @anushakarukola
    @anushakarukola Год назад +6

    I never thought it could be easy to understand such tough topics in a simple manner with less efforts ❤️❤️

  • @iqraahmad2451
    @iqraahmad2451 3 года назад +9

    I can't believe you have explained it so well. I have been dwelling on research papers for so long to connect these points.

  • @dr.s.choudhury8089
    @dr.s.choudhury8089 Год назад +1

    Not all heroes wear capes. Some make amazing video lectures for med students on youtube. Armando: The true legend! 🥰

  • @doc.jayantsingh9236
    @doc.jayantsingh9236 8 лет назад +32

    wow really helpfull in understanding the complex biochemical interaction at tissue and cellular level . thanx

  • @Scrubsandscreens
    @Scrubsandscreens 2 года назад

    This is the best I am not kidding . I am shocked how beautifully someone can explain such a complicated topic

  • @drtanveerahmed3373
    @drtanveerahmed3373 2 года назад +2

    This guy deserves a Nobel.

  • @cesarmichaelalvaradoibarra4215
    @cesarmichaelalvaradoibarra4215 7 лет назад +29

    Amazing explanation, neurology it's one of the most complicatedsubjects in medicine and you make it look so simple. Keep on the good work! (y)

  • @aleksandrassaraskinas713
    @aleksandrassaraskinas713 Год назад +2

    Thank you mister for making easy to study neurological diseases. It really helps me to prepare for exam!

  • @Dayv7
    @Dayv7 8 лет назад +42

    Brilliant as ever! Thought it was going to be a nightmare to remember the dysfunctional pathways involved but this makes it a cinch.

  • @c.b.2
    @c.b.2 2 года назад +2

    This was absolutely brilliantly explained! Thank you so much! I'll be sure to send all my med school classmates here!

  • @gloriaakinyode3279
    @gloriaakinyode3279 4 года назад

    VERY NICE VIDEO OF Parkinson dz. Never heard anything so CLEAR and detailed of Parkinson

  • @MaekaElaKimDimayuga-qx9rp
    @MaekaElaKimDimayuga-qx9rp 6 месяцев назад

    I subscribed because the information is very detailed. And for a nursing student like me, it helps very much. I will recommend your channel to my classmates...

  • @robertofernandez7195
    @robertofernandez7195 5 лет назад +1

    Nice. It is nice to mention that the Striatum naturally produces Acetylcholine, which also over induces the inhibitory pathway contributing to that Bradykinesia seen in Parkinson's. Great job!

  • @net28573
    @net28573 6 лет назад +3

    If I had resources like this video back in 2009 I would have self diagnosed my SSRI-induced-parkinsonism a long time ago. The most helpful point in this video for me is the differentiation of D1 and D2 in this motor circuit. You just saved me hours of research, good sir!

  • @laurenjohnstone9765
    @laurenjohnstone9765 8 лет назад +1

    You are magic.You make complex concepts seem so simple

  • @oliversykez7292
    @oliversykez7292 7 лет назад +4

    Thanks for this in a nutshell explanation! Very helpful in the end stages of studying for USMLE!!

  • @travisgrenke
    @travisgrenke 5 лет назад +1

    fantastic video. my roommate has parkinson disease. thanks for posting

  • @croock3
    @croock3 7 лет назад +4

    This a great video, fantastic for all levels of understanding and with amazing drawings. Really helpful, thanks!

  • @symbyxbiome
    @symbyxbiome 2 года назад

    Beautiful illustrations - a great way to teach. Thank-you. Would be good to better understand or explain some of the changes found in the gut microbiome of people living with Parkinson's, not just the brain.

  • @IR240474
    @IR240474 5 лет назад +1

    Thank you for this, great instructions and I love the pictures, I make mind maps but I will add this to them today for my exam tomorrow.. Thumbs up who is also cramming for exams!

  • @sdazxcf
    @sdazxcf 8 лет назад

    u r amazing to draw such complicated neuroanatomy into clear figures! salute to u

  • @danjbundrick
    @danjbundrick 8 лет назад +85

    Fantastic lecture. I learned a lot. One request: please throw that yellow marker away.

    • @XxwoodyleexX
      @XxwoodyleexX 8 лет назад +4

      +Daniel Bundrick agree.. it's too pale..

    • @danjbundrick
      @danjbundrick 8 лет назад +1

      Indeed.

    • @danielbedford6539
      @danielbedford6539 7 лет назад +2

      are you Yellow?

    • @AsgarAli-wh9vl
      @AsgarAli-wh9vl 6 лет назад

      Danimal Bunjee hi danimal i have a problem

    • @nectarandice
      @nectarandice 5 лет назад +4

      Another request: please throw the yellow marker at Daniel Bundrick.

  • @christinevakas92
    @christinevakas92 7 месяцев назад

    Wow, I really like in particular how to summarise the whole picture, how you show us the whole picture at the end, so helpful. When I see your video in our class readings, I know I am going to get great grades. Thank you for sharing your knowledge and talent.

  • @Greanestbean
    @Greanestbean 10 месяцев назад

    Great video, I only wish it also included treatment

  • @user-fh7lo6si8f
    @user-fh7lo6si8f 3 года назад +1

    Four months TRACKING improvement
    FIRST STEP: a UPDRS test, a push test with video, a walking and turning test with video, a talking test with video and possibly a writing test, standing from seated on hard back chair video with your arms crossed. These videos are kept on file to be used for comparison with future videos. This is a fairly accurate means of documenting improvements over time as it is actually fairly easy for some people to not realize how much they have improved over time.

  • @mariacabreragonzalez2
    @mariacabreragonzalez2 3 года назад

    I really like to watch these videos for some context before I study my teachers slides, this was great. Thank you!

  • @ju_7114
    @ju_7114 2 года назад +9

    Thanks you! You’ve taught me Parkinson’s in 14 minutes when my professors couldn’t teach it in a 2 hour lecture

  • @Self-actualizer
    @Self-actualizer 7 дней назад

    Thank you so much for all the efforts for making the concept sooo easy❤❤

  • @Enceladus007
    @Enceladus007 3 года назад +1

    Have to play this again.

  • @ummejoynabhabiba9484
    @ummejoynabhabiba9484 2 года назад

    Thanks for your amazing videos!
    Love from Bangladesh 🇧🇩

  • @balukujoseph3714
    @balukujoseph3714 3 года назад

    So amazing I understood the pathophysiology finally from here

  • @daocherry7014
    @daocherry7014 7 лет назад +1

    it helps a lot for my upcoming board exam. Thank you!!

  • @essamalielmisherghi9693
    @essamalielmisherghi9693 6 лет назад +1

    Thank you so much , this was really great Video lecture. Dr.Essam Elmisherghi from Libya.

  • @abhisheksinha4605
    @abhisheksinha4605 8 лет назад +1

    very concise n informative,thnx for video

  • @mercyngeru3924
    @mercyngeru3924 2 года назад +1

    This was very helpful. Thank you so much

  • @MrFASSOLY1990
    @MrFASSOLY1990 8 лет назад +5

    Little bit complicated 😅
    Thank you for your great efforts 👍🏻

  • @ЈованаКијановић

    wow thank you this saved my life literally

  • @bintenur6684
    @bintenur6684 2 года назад

    Very nice and easier presentation.
    Thanks

  • @leemouzee
    @leemouzee 6 лет назад

    Thank you so much! you explain so well and clearly, much better teacher than our professor.

  • @celestie02
    @celestie02 Год назад

    Great work sir!!
    11.48 when you said hope it makes sense, yess

  • @MPPSVennached-zd7yg
    @MPPSVennached-zd7yg 8 месяцев назад

    Nice explanation sir

  • @alexisdaniel3313
    @alexisdaniel3313 5 лет назад +2

    Could you explain why there is no tremors during sleeping? Why tremors start a couple of minutes after awakening ?

  • @buzzlair27
    @buzzlair27 8 лет назад +2

    This was really helpful for my next test, thank you so much.

  • @AyushiRai04
    @AyushiRai04 4 года назад

    Great Explanation!
    But how come smoking comes under protective measures?

  • @keruanmendonca6220
    @keruanmendonca6220 3 года назад

    Very good explanation

  • @lupo_mangiafrutta
    @lupo_mangiafrutta 2 года назад +3

    hi, do you have other videos on the basal ganglia or the neuro circuits? thanks i love your videos, you're helping so many med students out there :)

  • @BintyMcBintface
    @BintyMcBintface 8 лет назад +11

    Thank you so much for all your videos, I find them a fantastic resource!

  • @l.g.a.8930
    @l.g.a.8930 7 лет назад +1

    Excellent presentation. Many thanks :)

  • @anuradhamehta8281
    @anuradhamehta8281 7 лет назад +3

    Thank you soo much sir for putting up this video 👍👍
    It's amazing and time saving too !

  • @vishaldesai464
    @vishaldesai464 6 лет назад

    Thanku so much sir...I understood clearly about Parkinson disease from this video..

  • @maryaali9375
    @maryaali9375 5 лет назад

    mashaALLAH u have a very best way of teaching weldone sir kindly upload stroke ms hangtinton diesease vestibular disorders

  • @jaumepp1975
    @jaumepp1975 2 года назад +1

    Brilliant!!!

  • @okomosimon9941
    @okomosimon9941 3 года назад

    you are very bright. thank you for your share. i have read pathophysiology PD but i was not understanding. Now i understand it

  • @AaRtI0404i
    @AaRtI0404i 8 лет назад +1

    Thank you for the video.
    Can you please do a video on Traumatic brain injury?? Pleaseee....

  • @96areejfatima11
    @96areejfatima11 6 лет назад

    Thanks a lot for all of your videos.

  • @pharmacistkhan5969
    @pharmacistkhan5969 4 года назад

    Plz through that yellow marker... good lecture

  • @charmedbabe64
    @charmedbabe64 8 лет назад +7

    How is smoking a protective factor against Parkinson's? Does the nicotine help somehow?

    • @stubbornaneed
      @stubbornaneed 8 лет назад +10

      That was part of her name if you didn't notice she chose it, she is proud of it, and that is cool, so let me ask you, was the word "necessary" necessary?

    • @stubbornaneed
      @stubbornaneed 8 лет назад

      ok, hope you got it right.

    • @charmedbabe64
      @charmedbabe64 8 лет назад +1

      The name is from a Marina and the Diamonds song.

    • @DrArjunKataria
      @DrArjunKataria 8 лет назад

      it makes release of dopamine so somehow make it working..
      same like ejaculation decreases chances of prostate cancer in men

    • @cesusjhrist3913
      @cesusjhrist3913 7 лет назад +1

      Yeah, smoking weed helps as well, it's on youtube btw, look it up, a patient was really stoned but his tremor was absolutely gone. Ofc, it's temporary, but still is a thing.

  • @incognito5064
    @incognito5064 4 года назад

    You are a brilliant and talanted person

  • @dr.varsha8810
    @dr.varsha8810 5 лет назад

    Awesome lecture! Easy to remember.thank you

  • @EduLuminescence
    @EduLuminescence 5 лет назад

    Armando sir, you are just awesome...I am amazed... beautifully explained...love from India...

  • @srinivasyadavkasraveni7497
    @srinivasyadavkasraveni7497 2 года назад

    Fantastic explanation sir love you

  • @ahmadqubo
    @ahmadqubo 8 лет назад +1

    came in time ! thanks armando :D

  • @Veruvir
    @Veruvir 8 лет назад

    Loving the detailed flow diagram.

  • @A4arooj
    @A4arooj 6 месяцев назад

    i really needed this, thank you so much.

  • @raghadsrj3525
    @raghadsrj3525 5 лет назад

    You are literally the best!!!! keep going man and thanks a lot for ur efforts. Much appreciated

  • @TheChantelleBell
    @TheChantelleBell 8 лет назад +1

    perfect timing. csn you do one on alzheimers and cjd

  • @gulnazpathan4868
    @gulnazpathan4868 6 лет назад +1

    how amazing u explain us
    awesome memory sir u hav
    u really gorgeous ,,wonder,,fabulous ,,marvelous i really respect u
    plls make vdu over coma
    n epilepsy,
    schizophrenia

  • @wonderer112
    @wonderer112 5 лет назад

    Thank you for posting very clean explanation.

  • @bhargavibk3383
    @bhargavibk3383 5 лет назад

    A very good video sir! Thank you so much!

  • @eddel.6003
    @eddel.6003 8 лет назад

    Can you do one on Alzheimer's diseases and what occurs in the brain when the develop AD.

  • @ZaidKhan-eo6hn
    @ZaidKhan-eo6hn 2 года назад

    very helpful sir

  • @aliabdallah7833
    @aliabdallah7833 3 года назад

    This was vey helpful, thank you very much!

  • @fihimefihi
    @fihimefihi 7 лет назад

    concise and rich, thank you for the video

  • @Dennis.bergkamp
    @Dennis.bergkamp 2 года назад

    Thank you.You help me a lot for my research.

  • @rethnagireeshwar7199
    @rethnagireeshwar7199 8 лет назад

    admire you for this effects and effort . Thank you

  • @riaraizada7387
    @riaraizada7387 3 года назад

    Amazing content 🤩. Thank you 😊🙌🏻

  • @philipmilner9638
    @philipmilner9638 Месяц назад

    I have many of the symtoms you mention (some of my relitives thing I have Parkinson's disease), but I have many other illnesses including cerebral palsy, epilepsy and others). Should I try and see my doctor?

  • @sagarhansraj
    @sagarhansraj 7 лет назад

    Best. Video. EVER!!

  • @SuperJanni82
    @SuperJanni82 8 лет назад

    Thank you so, so, so much!
    Really awesome video!

  • @Dreeblet
    @Dreeblet 8 лет назад +1

    Thank you very much, this helped my understanding of parkinson greatly :D

  • @tinomutasa5371
    @tinomutasa5371 6 лет назад

    Amazing videos all round. Thank you

  • @inzerinzer5425
    @inzerinzer5425 7 лет назад +1

    Thank you for your video. Its great. You explain why person with Parkinson disease has hypokinesia and rigidity but dont give explanation for tremor ( your video is started with presenting tremor). And secondly, what do think about - why or how substanstia nigra is activating?

  • @hemantpaikrao4671
    @hemantpaikrao4671 5 лет назад

    Congrats for 1M subs...

  • @kainatfatima4662
    @kainatfatima4662 8 месяцев назад

    Your artistic skills tho💅😭❤️

  • @dineshphysio7462
    @dineshphysio7462 7 лет назад

    awesome lecture sir... keep going on...

  • @fawadahmad6739
    @fawadahmad6739 4 года назад

    Patient having tremors and rigidity lesion is in?
    Caudate
    Globus pallidus
    Nucleus basilus
    Lateral thalamic nuclei

  • @vickiryan7474
    @vickiryan7474 7 лет назад

    Incredibly Helpful THANK YOU

  • @drmannanbajwa8402
    @drmannanbajwa8402 5 лет назад +1

    You’re doing amazing work ..Thank you so much 😍😍

  • @almaquejada6893
    @almaquejada6893 2 года назад

    It caught me off guard knowing that smoking is actually a protective factor of Parkinson's disease 🤯 and coffee! Could anyone explain it to me? In my ignorance I thought those were actually risk factors.

  • @Homoeopathicore
    @Homoeopathicore 4 года назад

    I am Classical homoeopathic physician Homoeopathy is a science which treats holistically...
    Basic principle is all individuals are different so every individual is treated and given medicine totally different whether 2 individuals or more suffer from same disease...
    Not only this any individual who is suffering from one or many diseases at a time only one medicine will b given on the basis of his constitution...
    During case taking ( His medical history his family history his emotions intellect delusions fears hobbies choices manners sensitivity will power dreams physical general pathogonomic generals and peculiar symptoms and modalities all are taken into consideration to give his contitutional medicine...)
    Thats why in homoeopathy every disease is curable whether it is genetic auto immune chronic etc...

  • @Outthinkingparkinsons
    @Outthinkingparkinsons 7 лет назад

    A nice way to present and inform the public. Well done!

  • @noorraad2067
    @noorraad2067 7 лет назад +5

    👏👏thank you .Dr.Armando

  • @kienle-sk1hs
    @kienle-sk1hs 5 лет назад +1

    brilliant! thank you so much for making this video!

  • @virnan
    @virnan 6 лет назад

    You are gifted.

  • @VitorKururas
    @VitorKururas 8 лет назад

    Such a incredible video! thank you!