Understanding Parkinson's Disease (Including Direct and Indirect Pathways)

[@RhesusMedicine]

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Video Timestamps:
0:00 What is Parkinson’s Disease?
0:30 Parkinson’s Disease Pathophysiology - Basal Ganglia
1:10: Parkinson’s Disease Pathophysiology - Indirect vs Direct Pathway
3:36 Parkinson’s Disease Pathophysiology - Alpha Synuclein
3:56 Parkinson’s Disease Symptoms
6:05 Parkinson’s Disease Causes & Risk Factors
7:18 Parkinson’s Disease Diagnosis
8:47 Parkinson’s Disease Treatment
10:08 Parkinson’s Disease On/Off Phenomenon

[@vismayabiju1427]

Can u please tell the Reference?

[@thatexpertsim4874]

Glad it was a simple explanation

[@mahmudisiyaku9179]

Great one, highly simplified

[@RhesusMedicine]

Thanks!

[@FrankRuzicka-l5z]

A bit complicated but informative. I've been diagnosed with Parkinson's for almost a decade now.

[@paper_gem]

Best of luck to you, sir. Maybe there will be a cure soon.

[@svsportstherapy]

Thanks very much! Brilliantly explained. Now I need to learn it!

[@Beebleybees]

Such an amazingly explained video. Thank you!!

[@emmanueladegbulu-by4og]

Thank you so much. 🎉. This is simple and insightful.

[@RhesusMedicine]

Happy it helped!

[@adaezeozoagu5753]

Thank you so much for being a huge blessing

[@gdsal2552]

Thanks! Very clear

[@cbcifnrnciblh]

Excellent video. Well done.

[@muyundamubita9732]

Great presentation 👏👏👏

[@stevemiller6500]

Excellent video to medical students or young interns. Otherwise it way out my wheelhouse 😂😂😂

[@lydiamckenzie7011]

Super video !

[@gabrielemayer1366]

the muscles contrations goes wrong because it goes not the impulse settings to the cerebellum, because it goes to the tendons and not to the muscles fibers

[@danitajminer3279]

Excellent video.❤

[@somebody5126]

That was so helpful.. thank you

[@vismayabiju1427]

Can u please tell the Reference?

[@سهيالفرجابي]

really amazing and very informative

[@arhagbaisrael9228]

Very useful and helpful

[@RhesusMedicine]

Thank you!

[@Hashbrown1123]

I watched 3 videos none of them expained that the pars compacta affects the striatum. and this was leading to a whole new level of confusion. thank you for saving my life

[@er8017]

Why are tremors occuring if there's low movement
Also why is it resting if it's associated with motor cortex

[@lamihabasit5879]

bcos of unopposed effects of acetylcholine on direct pathway

[@er8017]

@lamihabasit5879 i get it but why would it be a "resting" tremor if it start with "intention of movement" from frontal lobe? Why wouldn't it be an "intentional " tremor?

[@shaurabhshukla2799]

Thanks sir ❤

[@er8017]

So this preceeds action of corticospinal tract right?

[@Latifakhat]

Very simple explanation😊

[@nyachwojuliet7144]

Amazing

[@raghadraghad7976]

Thank you so much

[@RhesusMedicine]

You're welcome!

[@neeleshsuryawanshi6590]

If there is reduction in movement then how tremors occurs?

[@nishar48]

I believe it is because of the lower dopamine causing decreased sensitivity and therefore a lower threshold for causing action potentials so this causes the resting tremors.

[@MIZZCHACHABABY91]

Is Parkinson’s something you can come and go out of like they confused and don’t know for a few days then next they know all of a sudden ? Educating myself

[@Jam-tc6js]

Thank you so much! :)

[@RhesusMedicine]

You're welcome 😊

[@sanjanachaudhari9496]

Notes?

[@vasujayaprasad6398]

Address digestive system and vertebral column injury for cure

[@souna9114]

Super ✨️👌👏

[@joeyong1418]

Check for tapeworms immediately!!!!

[@darkpearl348]

Great

[@lizzynatir9083]

Great things Dr Madida on RUclips has being doing for mankind, I undergo his Parkinson disease treatment plan for weeks and my Parkinson Disease was completely reversed...

[@drkpk384]

thx

[@lizzynatir9083]

Great things Dr Madida on RUclips has being doing for mankind, I undergo his Parkinson disease treatment🌿 plan for weeks and my Parkinson Disease was completely reversed..

[@alaeharkasse7974]

can you tell me more plz?

[@saniaz.4997]

For anyone that didn’t get it, try osmosis
I think this video was great too jbtw

[@america2793]

That’s just freddy with parkinson's disease

[@NoleenWainer]

Very complicated

[@danitajminer3279]

Molecular biology is complicated, although once you understand the basics, it's very easy.
Check out sigma metabolic pathway charts.
Start with bio. 1a , available from many top universities available on RUclips. ❤

[@lizzynatir9083]

Great things Dr Madida on RUclips has being doing for mankind, I undergo his Parkinson disease treatment🌿🌿 plan for weeks and my Parkinson Disease was completely reversed..

[@seantheguy1391]

You should be ashamed of yourself for shilling this herbal fraud

[@souna9114]

👌✨️👏

[@sandragriffiths9692]

You've lost me already....byebye

[@Ms.q0]

😂😂

[@goodnewsoziy9685]

Same here as well
What Uni you in

[@richmondaffumnimako7977]

What do U mean

[@notrealatall196]

Its a good video. May be u need even more simple and very basic level only. Though this video is straightforward and simple enough... depending upon ur field of practice and level of knowledge, u would need something else.

[@braxy0_0]

Bye have nice sleep

[@vishalchaudhary-nf6gr]

Planet Ayurveda's Parkinsonism medicine has exceeded my expectations. The natural ingredients and their holistic approach make it stand out among other treatments.

[@caesarkhudhair1747]

Please write only the first letter capital.