Hemostasis

[@nellsypie]

Ten years ago I qualified as a doc. I now work as an anaesthetist. In that time no one has explained the process as succinctly as you have. Thank you, you have simplified many daunting topics and your videos provide short, bite size revision points for post graduate exams.
Keep doing your thing !

[@jakesouth2]

Your videos are so clear and very well organized. After studying the subjects in my text, watching your videos solidifies and organizes the information in my head, and your graphics make it both entertaining and very easy to follow.

[@relentless5881]

If you cut deep enough is there a point where the damage done is not repairable, For example deep enough that tendons is cut completely.

[@mjabbar28]

Watching in 2024

[@zeynep944]

Me too 🧕🏻🙋🏻‍♀️

[@Gounesh]

Still relevant 👌🏻

[@mrzirker]

Me.too

[@alanoudmusaad5034]

you keep saving my life dude. im a PBL student and ur channel is basically the only "teaching support" i receive so thank you so much for the amazing videos

[@Huntho21]

You literally complete my PBL each week. Thank you su much for doing these videos.

[@beca1973]

I am an MLT going for my MT. I must say, these make a wonderful refresher, furthermore, The way you explain it and the visuals (as you know must of us are visual learners) make it so much more easier to comprehend. Thank you so very much! If you need more sharpies, let me know. Fantastic job!

[@vjlaxmipanna8572]

hey I'm a final year medical student, I'm watching it few days before my medicine paper. It's really helpful and awesome ❤️

[@sycamore0765]

TBH, I got 50/50 in my SGD(Student Group Discussion) in my AnaPhy class about the video you posted about Bone Fractures and Bone Repair. THANK YOU SO MUCH

[@tatheerfatima3263]

I'M so happy today because after one week finaly i understand this topic thoroughly... May God give u more success

[@onlinestudent-ht8sc]

this has made such a confusing and complex process into a very understandable lesson in 10 minutes, thank you very much. the drawings and layout are incredible

[@jojoyusri1608]

this video very helpful to me.. my God! my final exam coming soon.. while i'm not clearly understand about hemostasis.. when I watched this video.. clearly! now I understand about the process! thank you!

[@teamhope525]

We should all pay our tuition fee to u!

[@talkwithberryl7288]

you are dam right my friend, i wish he was my teacher such an excellent job he does all the time

[@RxlredE]

It takes so much time to draw like that.. he drawing can make it very easy to understand. He's doing us a favor by speeding his videos. He is the best.

[@Hoviking]

tuition fee is 200 dollars a year, he deserves it all

[@folawiyosulaimon1647]

Omo
No lies oooo

[@sushandhakal1367]

man i am in love with your teaching style!!

[@katiekelly6896]

I wouldn't be passing nursing school if it weren't for you. Thank you a million times over....you are amazing!

[@EvilMia1]

I agree... Armando! You are my saviour in medschool!

[@ranceeenadela3157]

Thank you for your effort! A simple yet brief explanantion of hemostasis. God bless!
-a student nurse 🤗

[@ajboswell]

Video proved really useful for my dissertation work related to platelet coagulation. I often watched this to ensure I remembered the functions of all the agonists involved. Keep up the work buddy, great channel!

[@shabbabkhalaf5590]

توم جيري

[@bubblygal]

your 10 min video taught me what i was struggling w for 3 hours. God bless you man

[@pdc293]

Seriously, I was a little skeptical about watching this video at first because there are not that many views on it, but it is exceptional!

[@roofarrow32]

Awesome!! Thank you. You broke down that process in a simple, easy to understand process! Appreciate it.
-first year med student

[@sjayveenth]

+Rufaro Mutepfa ikr

[@latifaalnaemi412]

Now you are in your fifth year hehe

[@asifhamid9676]

Ultimate lecture sir.
You are explaining n writing everything in easiest possible way.

[@jiminshighnote]

I've watched 2 videos and read from 2 books about this topic but I like your video the best. It is the clearest and most organised. It's easier to understand. Thank you so much!

[@Aaron_Orion]

You're a life savior! Who would know hematology is so fun yet so complex

[@carissapurabaya9893]

Pembuluh darah yang mengalami kerusakan akan mengalami proses blood clotting dengan mekanisme:
1. Vasospasm/Vasoconstriction
(vasodilatasi terjadi bila non-injury cell)
Otot polos pada pembuluh darah akan terkonstriksi untuk mengurangi aliran darah. Signalling vasokinstriksi dilakukan oleh :
- Cells around area sends signalls
- Nerve reflex
- Myogenic Spasm
2. Platelet Plug Formation (platetet membentuk temporary plug untuk menghentikan pendarahan). Dilakukan dengan 4 cara :
- Plug Adhession
Von Williebrand Factors mengarahkan platelet/trombosit untuk menempel pada sel yang mengalami luka, platelet akan menempel pada daerah luka tersebut
- Platelet Release Reaction
Platelet mengeluarkan adenosin bifosfat (untuk menarik platelet lain) & serotonin protrombin A2 (meningkatkan Vasospasm & menarik platelet lain)
- Agregasi Platelet
Pengumpulan platelet pada area luka sehingga membentuk platelet plug formation
- Plug Formation
Penutupan daerah luka oleh platelet sehingga menghentikan pendarahan
3. Coagulation, berfungsi untuk memperkuat plug yang dibentuk platelet
- Intrinsic & Extrensic Pathway (clotting factors)  Protrombinase (aktivasi protrombin) yang berperan sebagai ‘lem’ untuk memperkuat plug
- Protrombinase dibantu dengan Ca2+ mengkatalasis :
Protrombin (inaktif) -> Trombin (aktif)
- Trombin dan Ca2+ menjadi enzim dalam perubahan :
Fibrinogen (soluble) -> Fibrin (insoluble)
Benang-benang fibrin akan menempel di seluruh yang kemudian menutup luka tersebut.
Thanks!

[@martinsmith6534]

Thank you for the indepth explanation. your tutorials and handsomely drawn diagrams are on point and well explained to help one (us) understand in a quick possible way. keep up the good work and helping us

[@scienceqila3993]

It's all amazing.
Correlation is superb.
Being as a fresh RUclipsr,your short pithy lectures are quite helpful for me:)
Thumbs up Ormando❤

[@DavidL999]

Thanks, I always watch a ton of your videos when my exams are close, they always help!

[@gurusekhar1843]

After searching many videos, I found this helpful

[@sarahferay8560]

Whaou ! BRAVO !!!
(From a French Anesthesiologist Resident)

[@nhivuong6593]

thanks you very much (from a Vietnamese Pharmacy Student)

[@akaruitaiyo]

thank you very much!
Just a gentle reminder to correct certain spelling mistakes. like... Extrinsic, not extrensic. But generally, your videos really help! thanks

[@rylle_rd]

Galing mo kabayan .. very nice illustration

[@dr.leelaram]

Your explanation is outstanding Sir❤❤

[@amixaex]

THANK YOU for existing and making these videos !! They're freaking amazing and to the point unlike other videos that go on and on for ages !! my life seems so much easier now hahaha !! PLS KEEP MAKING VIDEOS !!

[@hollycox7580]

THANK YOU SIR. i have an anatomy exam soon and this helped so much!!

[@ronshmilovich2481]

Very clear and well informed. Didn't explain what are the von williebrand though.

[@mizukisuzuya3364]

this video is helping me so much with my extended response on haemostasis. thank you so much for such a clear explanation

[@aadino_]

Really help me in studying pharmacology

[@annnolan6355]

Love your video ... I have used them over and over for my advanced pathophys class ... appreciate all your work!!!

[@AvrahamDubinsky]

Very well put thank you

[@TropicalChris]

Great video, thanks! Could you possibly do one specifically on the coagulation factors (I thru XII) while explaining them? That would be a great addition to this :)

[@nkosinathimlingo3078]

These videos makes my future so bright

[@shaziabdulrahim57]

cn u pls make a video on intrinsic and extrinsic pathway?

[@mastkt]

ruclips.net/video/s4FoSf6Yi_s/видео.html

[@Apratim98]

Check out mine for the same..

[@yarghhargh9345]

Amazing, this man is studying medical science

[@talkwithberryl7288]

wooow i luv your videos, pls dont stop making good videos you have no idea how much you help students like myself.

[@xydian4282]

I'm just an Engineer, but I love watching this stuff.

[@emmapaulus99]

this was so helpful in bringing all the steps together in a cohesive manner...thank you!!

[@CatStealer1]

Just want to say your videos are awesome and really helping me with my degree!

[@jnubkk]

You make everything *click* for me! Thank you for your contributions to students trying to understand how it all fits together! Keep it up, I'll gladly donate as soon as I graduate and find a job :)

[@jasonmyer3615]

Beautiful and easy to understand presentation... love ur way of explanation.

[@alexiiiiii_10]

This video was accurate and pretty clear. It helps me to review our lesson with visual!. Thank you!

[@ArienScent]

Thank you

[@savannahscott96]

Great video!!! I really appreciate how well thought out the organization is!

[@angeloquimoyog6448]

I love your drawing. It is visual which enhances my learning of the concept. I wished my professors can learn from you, this way is more interactive and appealing which helped me focus at listening throughout the video. Thank you!

[@lisagonzalez2902]

This is extremely, so incredibly good. I can't even describe it. Thank you sooo much. A lot of information, but actually important stuff, and not soo much that it becomes overwhelming. Thanks!!

[@lisaraye2007]

im not in med school but I am in medical lab science program and this just saved me lmao!!! yes thanks alot

[@igorpassioura2769]

You're a boss dude. I use these in my medical studies. You're a great help!

[@rahulpal8659]

Bro you are too good. But please one video on intrinsic and extrinsic pathway

[@davidkitt6457]

cant stop thanking you

[@McLen194042]

I just had a test on this Monday!

[@ashrafzaharaimi3728]

Awesome explanation easy to understand....magnificent work of art..thanks

[@muhanadsomali4565]

Thank u proder

[@StanRech]

Greetings from Mexico and thanks for the video

[@raulvera3017]

Brief, informative and helpful. Thanks!

[@LiveYourOwn]

combining science and art... thanks... i would never understand about hemostasis if i didn't watch this video.
God bless you and your talent :)

[@fadliafardhana9431]

Terjadi pada pembuluh darah yang mengalami kerusakan. Berlangsung dalam 3 tahapan mekanisme
• Vasospasm atau disebut vasokonstriksi
Pada saat pembuluh darah mengalami kerusakan, maka eritrosit akan keluar dari pembuluh darah. Otot polos kemudian akan berusaha untuk mengurangi aliran darah dengan cara terkonstriksi. Vasokosntriksi ini terjadi karena proses signalling:
 Sel di sekitarnya mengirim sinyal
 Nerve reflex
 Myogenic spasm
• Platelet plug formation
Platelet membentuk temporary plug untuk menghentikan pendarahan. Terbagi atas 4 tahapan:
 Platelet adhession. Terdapat Von Williebrand Factors dalam darah, berfungsi untuk mengarahkan platelet agar menempel pada daerah sel yang mengalami luka, sehingga platelet menempel pada sel yang luka.
 Platelet release reaction. Platelet mengeluarkan adenosin bifosfat untuk menarik platelet lain ke daerah sel yang terluka serta mengeluarkan serotonin protrombin A2 untuk meningkatkan vasospasm dan agregrasi platelet.
 Agregasi platelet. Terjadi saat platelet dalam jumlah yang banyak berkumpul di daerah sel yang luka dan membentuk platelet plug formation.
 Plug formation. Daerah luka akan tertutupi oleh platelet untuk menghentikan pendarahan. Platelet plug formation akan menyebabkan aliran darah yang keluar menjadi semakin melambat. Namun penghentian pendarahan ini hanya bersifat sementara, sehingga perlu adanya mekanisme lanjutan.
• Coagulation
Pada proses ini dibutuhkan clotting factors, protrombin, dan fibrinogen yang terdapat di dalam darah. Koagulasi berfungsi untuk memberkuat platelet plug formation. Terdapat 3 tahapan mekanisme koagulasi yaitu:
 Intrinsic dan extrinsic pathway, dimana jalur keduanya menghasilkan protombinase berfungsi untuk mengaktivasi protrombin. Protrombin berperan untuk memperkuat platelet plug seperti sebuah “lem”.
 Protombinase dibantuk oleh Ca2+ yang berfungsi sebagai katalis yang akan merubah protrombin menjadi trombin.
 Trombin dengan Ca2+ akan mengaktifkan enzim untuk merubah fibrinogen menjadi fibrin. Benang-benang fibrin akan menempel di seluruh luka dan akhirnya menutup luka tersebut dengan stabil.
Setelah proses penutupan luka selesai, pembuluh darah tidak akan terjadi vasokonstriksi lagi dan aliran darah kembali normal.
Thank you for the explanation

[@magdamunoz8850]

very well done thanks. I am addicted to your videos

[@outlaw6343]

Amazing overview of Blood Coagulation!!

[@therobostever8838]

I like to believe Armandos real last name is Hadouken.....thats how il'l always read it...its the little things in life...

[@Syed-Amaar]

TO B HONEST U HAVE SOME SPECIAL GUTS OF TEACHING
HATS OFF BRO❤❤

[@rajazubair6699]

Excellent video it helps me alot to understand basics of hemostasis

[@minnieyoo9239]

Thank you! This is so much easier than I thought! My teacher sucks at explaining

[@saicharanvarala2492]

You are really awesome man...I am right now loving physiology just because of you...the way you explain is making me feel that if any one asks me to explain it I'll try to do it in this way or I'll just show this

[@hassanbilal4036]

its really very concise and helpful...GOD bless u Sir

[@mrsdiggory3211]

I LOVE IT, I have a presentation for this chapter and this really helps me! thank you!

[@skatesandkicks5935]

Thank you Armando. This is a brilliant video. Simple and easy to follow.

[@angelbertoblancoblanco5286]

Awesome video, your artwork and explanations always clarifies it for me, thanks.

[@Baharaakbari]

Thank you so much 😭you are so amazing person without you I would never get understand medicine lessons no words to thanks more

[@alinaali8606]

awesome and attractive explanation
kindly post some pharmacology ANS videos based on drugs

[@jaclyngonzalez6501]

Thank you so much. when i heard it in my class i was so confused. This video helped alot!!

[@bluepoop7365]

thank god u are alive!!

[@sudheerasampath4589]

What a nice explained . Thanks

[@charissemarietoledo2820]

Thank you. This made me understand and remember basic information in prep for my usmle exam. GOD bless

[@SaiwanMaerufSaiwanbio]

thanks for this video why you did not mention about coagulation factor ?? , i hope you will make a video about the action of plasmin ( fibrinolysis ) .

[@Apratim98]

Check out mine for the same..

[@Therian183]

Really your videos are very clear and informative

[@TheKaydax]

this was a very good demonstration. thank you!

[@bimenyimanajeancloude7352]

much credit for this work thank you

[@trianahardianti]

THANK YOU. watched one video and clicked subscribe button immediately.

[@latoyaparker35]

Simple and easy to understand. Thankyou!

[@nzhrhm]

YOU. ARE. A. GENIUS.

[@pinakichall5462]

Very nicely explained! well done.

[@Sazzist]

woow, you're videos are amazing!!! I had kind of a hard time learning this and you drawings makes it much easier (and funny)! Please upload more xx

[@surdigital9851]

Very good explantation. Thanks

[@bettymosenye8471]

thank u so much...u broke down the process to become easier

[@subhobiswas5870]

Cell injury video plz

[@nedaaden31]

I watched one video and befor the 02:00 i had already subscribe,you are awesome

[@drarsalansajid1]

video on coagulation cascade please..

[@5757-d4j]

Great teacher❤

[@alexhenwood5717]

So incredibly helpful!!!! THANK YOU!!!

[@angelhoskie8793]

i really understood this video very easy to understand too i love this video
keep doing what u are doingg!!!

[@lev.shcherbakov9404]

Thank you very much for your videos! Greetings from Russia.

[@noone11818]

Great work as always,
You've always been very helpful to me.