Transgenic mice

This biotechnology lecture explains the process of transgenic mice development and the application of transgenic mice in molecular biology.
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[@swapnilbangar3381]

please check the genetic material has to inject in female pronucleus or male pronucleus. as per my knowledge the genetic material is injected in male pronucleus

[@jasminebreaux9047]

Your videos have been extraordinarily helpful for my upper level bio courses. Thank you so much and continue the great work.

[@shomusbiologyofficial]

+Jasmine Breaux thank you. Glad you liked my lectures

[@taniabatool4451]

Congrats for 1 million subscribers❤. I m so happy for this.

[@subhomaychakraborty45]

It is really awesome and fascinating.

[@dhanrajkumarverma]

hey suman you are a awsome teacher your lectures are just wow

[@asmaa7888]

Great explanation thank you

[@amnaj5943]

You're the best!!! Thank you

[@MrOmniFicent]

Great explanation, however, the male pronuclei is larger than that of the female pronuclei (at least for mice).

[@madamequeenie]

This man has been saving me from high school!!

[@meaganhennessy9048]

Would homologous recombination replace both of the original genes simultaneously or is there a possibility for the generation of heterozygous mice from that first injection into the pronucleus where the blue gene replaced the black one

[@salikiyahidris5698]

Thank you!

[@anitasoni8494]

nice explanation

[@kp63988]

Can u explain abt the transgenic Methods

[@abdullahyusuf190]

Is it possible to reverse a transgenic mouse and return it to the wild type form?

[@WhitehorsePatriot]

Thanks for the lectures, but why put so many adds on the video. I can hardly read whats on the board.

[@abhishekrana5933]

What is difference between Transgenic and knock out mice ?

[@akshatavaidya8281]

Sir.. Please make videos on transgenic methods like retroviral vector , micro injection etc ! ...

[@shomusbiologyofficial]

Okay

[@bhaavz8655]

Bhaiiiii...can u plzzzz share a vedio on a topic of public awareness of the processes of producing transgenic organisms.....plzzzz.

[@undertaker8508]

Why do we use alpha MHC promoters in transgenic mice

[@bikramroy3783]

Sir I read the male nucleaus is lager then female

[@pawarjay9143]

yes absolutely i got a 4th edition (glick) it has mentioned in it

[@samuelkaushal2007]

Note that in mice the male pronuclei tends to be bigger than the female pronuclei.

[@3829ss]

Thank you~

[@sandhiyan6399]

What is the major difference between transgenic mice and knock out mice in simple

[@shomusbiologyofficial]

Gene knock out can be used as a technique to make transgenic mouse

[@sandhiyan6399]

@@shomusbiologyofficial thanks for clarifying

[@rrsrk2424]

Sir please make video
On Nuclear transfer....

[@shomusbiologyofficial]

Okay

[@elieganni2426]

Uhm, no. The process is random; you have no control over where the gene goes. If you want to control where the gene goes, you need to select for true homologous recombination through a different process that utilizes g418 and ganciclovir .

[@messengercrow]

not always you substitute a gene

[@banjaelina354]

Will you plz do in Hindi sir

[@shomusbiologyofficial]

Sorry. Stop this Hindi English language thing. Higher education require you to lesrn English. So please do that