What Hormones Are Affected By Caffeine?
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- Опубликовано: 3 окт 2024
- Have you heard different information about caffeine and its effect on hormones? Maybe you are wondering what hormones are affected by caffeine. In this video we look at research behind caffeine and its effect on hormones. We will look at how it affects cortisol, insulin, testosterone, and sex hormone binding globulin.
Research articles
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Caffeine excerpts its effect on many different hormones but most effects seems to be on cortisol, insulin, and testosterone. Let's look at cortisol first. In this study, researchers looked at the effects of oral caffeine on plasma ACTH levels and cortisol levels. ACTH comes from the brain and it stimulates the adrenal glands to produce cortisol, DHEA, and other things in the adrenal glands. Following caffeine consumption there was significant elevation of ACTH at all times 30 minutes to 180 minutes. Cortisol is also elevated starting at 60 minutes. For this study it looks like they used about two to three cups of coffee. The main conclusion of the study is the effect of caffeine on hormones and they concluded that caffeine is exerting itself on the pituitary adrenal axis. The caffeine is stimulating the pituitary to produce ACTH which then increases cortisol. There are probably other effects going on in the body as well. This pituitary adrenal axis was the angle of this particular study.
Caffeine Affect On The Hormone Insulin
Caffeine also seems to have an effect on insulin and it makes sense too since insulin and cortisol have posing effects on glucose. There are several studies showing that caffeine consumption does decrease insulin sensitivity and cause higher level of insulin to be produced. This randomized double-blind placebo-controlled trial study looked to understand the relationship between caffeine and insulin. It was a fairly small study so the conclusions should be taken with a grain of salt. They looked at consumption of 200 milligrams of caffeine taken twice a day which is a fairly large amount. The participants took this amount for seven days. They looked at the effects on glucose metabolism, serum cortisol, DHEA-s, insulin, androstenedione, and bedtime salivary melatonin. They found is that serum insulin levels were significantly higher in those consuming the caffeine than other parameters. Glucose, androstenedione, DHEA and melatonin were not changed. This may be a little confusing by the glucose not changing but allow me to break this down a bit.
Glucose will not go up or down as long as the body has sufficient insulin to keep the glucose in check. Insulin acts to put glucose into the cells and tissues. Cortisol takes glucose out of the tissues and puts it into the blood. So if caffeine is increasing cortisol, we expect the body to also need more insulin. This is what the researchers found. Over time that higher amount of insulin may lead to decreased insulin sensitivity and higher glucose levels, aka insulin resistance.
Caffeine Affect On The Hormone Testosterone
What is the affect of caffeine on testosterone and other androgens and the overall androgenic effect? There are few different angles to consider with this, like sex hormone binding globulin (SHBG) and actual androgen levels. One study looked at the effect of caffeine on testosterone levels and they found that consumption of caffeinated coffee increased total testosterone but decreased free estrogen and testosterone. Among women decaffeinated coffee decreased total and free testosterone and caffeinated coffee decreased total testosterone. This does not present a clear picture of what's going on.
Another study looked at the effect of caffeine on training. Many people take a pre-workout supplement or drink coffee before the gym. What kind of effect does this have on your body? It looks like caffeine has some potential benefit on training outcomes via the anabolic effects. For instance, if you are able to increase the overall output of exercise you do, maybe you could do more sets more reps, this causes your body to produce more testosterone. That increased workload, with the caffeine, causes your tissues and hormone centers in your brain to increase testosterone production. However, that increased testosterone effect may be counteracted by the catabolic effects of caffeine and cortisol.
Caffeine consumption may not always be aligned with your exercise goals. If your goal is purely to increase muscle, high caffeine levels may work against you because of the cortisol. If you're trying to trim down and put on muscle, caffeine may help you with both. This is because higher cortisol has a catabolic effect but increased testosterone from increased work loads has an anabolic effect. Another important variable when looking at androgens and testosterone is the effect of caffeine on sex hormone binding globulin.
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I went from coffee to decaf to Teeccino herbal coffee, it's tough to quit caffeine but it feels nice at the end
Nice I’ve done that before too but it’s been a while
“Caffeine increases SHBG”
That’s all I need to know. No more caffeine.
As simple as that. Bye caffeine hello gym gains.
Haha
SHBG- caffeine bad news
@@JoeLLHern Incredibly wrong lol... u dont want low shbg my guy thats old understanding. SHBG is not just that thing sitting in your body waiting to kidnap your free test and gains. SHBG has many functions and it is that thing that decides what tissue gets what test at what time. SHBG is not rendering your test useless its the opposite , its like a freezer , if your androgen receptors are saturated at any point and u dont need or use the testosterone properly it stores ( binds ) the test and release it at other hours when ur receptors are needing it. It is better utilization of test instead of being with crashed shbg and all the test is free and wrecking havoc randomly causing acne and stuff. U want ur shbg around 35-50 mark and never bellow 20. This bro science that u want shbg crashed with proviron and what not is so dumb its beyond me.
As for coffee causing insulin resistance ... also wrong . There is a specific literature on long term coffee consumption and the evidence are clear that longer consumption of coffee and caffeinated drinks DOES NOT CAUSE insulin resistance or sensitivity in non-diabetic , pre-diabetic and diabetic individuals.
Now .. if you for some reason walking around with shbg over 70 ok u need it lower , but otherwise u need it around mid or low-upper range.
@@swintegrative why didnt you include the studies that allegedly showed increased SHBG in males? you showed three studies that didnt show that and then just mentioned it? show the studies
Thank you for talking about this topic. It's so interesting. 🙏
Glad you enjoyed it!
caffeine sucks.... for some reason my body just stopped enjoying it. insomnia gut issues....
Great information, thank you!
Glad it was helpful!
Can you please advise on how to increase the metabolism of caffeine, and speed up it's removal from the body? Since menopause I have had to completely eliminate any caffeine, including foods containing caffeine-like substances such as dark chocolate. I can no longer enjoy Green Tea, even first thing in the morning, without it causing bad insomnia that night. It's quite frustrating. Actually even decaffeinated coffee causes insomnia for me.
I am only interested on the effects of DHEA .
I have insane pains in my stomach,ovaries etc whenever i drink coffee at my fertile days or menstruation...
That sucks… probably has to do with high estrogen/histamine.
@@swintegrative
probably low progesteron...but coffee is making problem much worse
Hey Doc. I quit coffee In January and then TRT in May. I tried coffee again after that and it gives me horrible brain fog.
Could this have something to do with an HPTA reset? It didn’t use to do this
Thank you!
Well that’s interesting and a good theory. I don’t know though. Typically when things are resetting after stopping TRT people feel tired and feel better with stimulation.
Decaf has caffeine
Does decaf affect hormones?
I don’t think so.
I have PCOS I gave up coffee. But I drink matcha and I do fine with matcha or black tea . It gives me long steady energy zero crash .I just make sure to drink it at 2 pm because We humans are meant to have the high peak on energy naturally in the morning time .
2pm too late for me
@@iamincrediblystupidbut4364 for me 2 haha now I drink black tea early
I had a period where i had about 4g of caffeine daily, i have been "clean" a week now
4000mg of caffeine? Daily? You wouldn't sleep lol
yes i did.@@healthiswealth1452