Complement System - An Introduction

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  • Опубликовано: 29 окт 2024

Комментарии • 183

  • @RohitPant04
    @RohitPant04 2 года назад +13

    That background music took me to the early 90s. Thanks for that!

  • @oumaaima1613
    @oumaaima1613 5 лет назад +16

    words arent enough to express how thankful i am

  • @CieraAndDanielle
    @CieraAndDanielle 7 лет назад +261

    My Immunology course is currently ripping me to pieces and this video gave me a sliver of hope.

    • @3APNHA
      @3APNHA 6 лет назад +1

      HMX Immunology?

    • @andrelomedico1473
      @andrelomedico1473 5 лет назад

      3APNHA its a branch of medicine

    • @aminezaidi4089
      @aminezaidi4089 5 лет назад +9

      @@andrelomedico1473 not of my business, but she's asking whether she's asking immunology course on Harvard (HMX) or not.

    • @alialrubaie8905
      @alialrubaie8905 3 года назад

      ها بشري نجحتي لو لا

    • @shamsghalib2718
      @shamsghalib2718 2 года назад

      @@alialrubaie8905 صارلها ٤ سنين اكيد نجحت😹

  • @GermaeAnne
    @GermaeAnne 2 года назад +4

    This was the ONLY demonstration that made me finally understand the complement system paths!!!! Thank you sooooo much!!!!!

  • @atp_3249
    @atp_3249 5 лет назад +21

    you guys need to make more videos like these! they are super helpful!

  • @lizzieschmitz7010
    @lizzieschmitz7010 4 года назад +11

    You’re the real MVP for making this!!!

  • @samuelmashabela840
    @samuelmashabela840 7 лет назад +38

    Incredible! this teaches me about how my body works, and helps me understand the immune system in my body. Thank you very much.

    • @mdr7587
      @mdr7587 7 лет назад +6

      Samuel Mashabela are u a 5 year old?

    • @Dawndrea2David
      @Dawndrea2David 7 лет назад +1

      Samuel Mashabela ok mon

  • @ashandeepkaur4527
    @ashandeepkaur4527 3 года назад +6

    Thank you sooooooo much........this just saved a whole ass unit in immuno.

  • @dyannealexandraguzman436
    @dyannealexandraguzman436 2 года назад

    final exam tomorrow and i really feel like i learn better from videos like this and is perfect when you want a quick summary to complement your notes.

  • @berasehebi5464
    @berasehebi5464 3 года назад +1

    This is the definition of perfection.

  • @onetallgirl1369
    @onetallgirl1369 5 лет назад +18

    Perfect video!! Thank you for being so thorough! Maybe I won't fail my first immunology test after all! lol

  • @yogayantra
    @yogayantra 6 лет назад +16

    Quite amazing! thank you so much, now i can get back to my immunology course, and will certainly understand it, for once.

  • @ariyakashyap4990
    @ariyakashyap4990 5 лет назад +16

    This was a great video and really helped me understand the concept. Thank you so much and Please make more such videos

  • @lostSempaiWissame
    @lostSempaiWissame 3 года назад +1

    Most helpful video in the universe ❤️❤️❤️❤️❤️ wish everything was explained like this

  • @gurkiratsingh4157
    @gurkiratsingh4157 3 года назад +2

    Great detail of explanation with superb animation
    Bring more of such videos

  • @suneetathapa4590
    @suneetathapa4590 6 лет назад +2

    Thankyuhh very much for such fantastic illustration!!!! Now i get to know way better than how my professor taught!!

  • @ThatOneScienceGuy
    @ThatOneScienceGuy Месяц назад

    Beautifully explained and illustrated.

  • @MrMattaiusify
    @MrMattaiusify 5 лет назад +1

    You diamond. My lecturer couldn't explain this at all. Thanks x

  • @redaniosnguh9295
    @redaniosnguh9295 3 года назад +2

    I love this video Soo much
    I will like another one like on T and B lymphocytes

  • @dop-xf5uw
    @dop-xf5uw 5 лет назад +1

    That video makes the complement system simple

  • @anandkishor2791
    @anandkishor2791 Год назад +1

    Thank you for this wonderful video 🙏

  • @ogbanyaemmanuella8879
    @ogbanyaemmanuella8879 3 года назад +1

    Wow I'm grateful.

  • @HudaMatbuli
    @HudaMatbuli 5 лет назад +3

    It's never been this easy. I can't thank you enough

  • @cindykosgei2853
    @cindykosgei2853 3 года назад +1

    God bless you for this

  • @sudiptoshahin
    @sudiptoshahin Год назад +2

    C2b+C4b is the C3 convertage as I know.

  • @iqbalreehal2446
    @iqbalreehal2446 5 лет назад +2

    This is ridiculously good, THANKYOU

  • @vrushalibarmukh2497
    @vrushalibarmukh2497 3 года назад +2

    Very informative and also amazing way to understand complement pathway thank you so much 😊☺️

  • @omotoladavid5272
    @omotoladavid5272 2 года назад +1

    Thank you so much for this

  • @nesrinech3967
    @nesrinech3967 3 года назад +1

    thank you so much for this life saving video.

  • @paulaschrodinger4681
    @paulaschrodinger4681 5 лет назад +6

    Thank you so much, this video is so helpful.

  • @baharehfatemi325
    @baharehfatemi325 7 лет назад +2

    Fantastic! Very helpful video. Thank you!

  • @blackyme2889
    @blackyme2889 3 года назад

    thank you for giveing us a clear vesion to keep in mand about complement,, algerian pharmacy student here ^^ thank you brother

  • @shamsghalib2718
    @shamsghalib2718 2 года назад +1

    very well explained. thank you so much you are a life saver

  • @FiFAWorldCupQatar-er3yj
    @FiFAWorldCupQatar-er3yj 3 года назад +1

    Highly appreciated

  • @zilinzhu210
    @zilinzhu210 5 лет назад +9

    This helps so much! Great explanation and animation!

  • @ph.tohamaalahmad124
    @ph.tohamaalahmad124 2 года назад

    عظيم ..شكراً لجهودكم

  • @cinthializeth5968
    @cinthializeth5968 5 лет назад +29

    historically the larger fragment of C2 was called C2a but is now referred to as C2b ****

    • @raheelshafi882
      @raheelshafi882 5 лет назад +3

      Cinthia Lizeth
      Not true. All literature uses 2a.
      Abbas, in his Basic Immunology book several years ago, tried to make this change but went back to the 2a designation.

    • @pecatum666
      @pecatum666 4 года назад +1

      @@raheelshafi882 however it's used used by major scientists in the field, e.g. Daniel Ricklin

  • @rokinco8598
    @rokinco8598 5 лет назад +3

    Interesting, this video said that the small pore allows water, ions and small molecules into the cell for lysis. While my lecture notes say that the small pore formed causes the contents of the cell to spill out

    • @rowan729
      @rowan729 5 лет назад +1

      Probably depends on the osmotic pressures and solubilities of stuff both inside and outside the cell, which will determine whether water will go in or pour out.

  • @bloba4443
    @bloba4443 3 года назад +1

    I have no idea what this is but it is interesting

  • @Katherinecam12
    @Katherinecam12 3 года назад +1

    This is so good!!! thank you so much!!

  • @anatolyrozhkov851
    @anatolyrozhkov851 5 лет назад +3

    Superb explanation, thank you!

  • @jenniferharrison7677
    @jenniferharrison7677 3 года назад +1

    Great video! Thank you!!

  • @yashaswinivyashaswiniv7124
    @yashaswinivyashaswiniv7124 3 года назад +1

    Wonderfully explained

  • @raniahassan7035
    @raniahassan7035 2 года назад

    I love it I understand the complement system finally 🙌 thanks 😊

  • @Mairaa-xo3rf
    @Mairaa-xo3rf 11 дней назад

    Finally Immunology seems a little bit easier!

  • @swethagajula9154
    @swethagajula9154 4 года назад +1

    Amazing and extremely clear explanation. Great animation👍👌

  • @catija
    @catija 4 года назад +1

    Amazing video!

  • @olawaleadejumobi6624
    @olawaleadejumobi6624 7 лет назад +2

    beautifully illustrated

  • @SameerAli-fe9xx
    @SameerAli-fe9xx 3 года назад

    Thanku sir for this helpful video.I'm from India

  • @mouhamedalpehanyalpehany7558
    @mouhamedalpehanyalpehany7558 3 года назад

    Thank your sooo much... Excellent very,,,, معهد الدكتور أمين ناشر اثبتوووو وجودكم 👨‍💼👨‍🔬. 👨‍🦱 ومن يتهيب صعود الجبال يعيش طول الدهر بين الحفر

  • @giorgiafaggiano2878
    @giorgiafaggiano2878 2 года назад +2

    are c3a and c5a opsonin molecules?

  • @olawaleadejumobi6624
    @olawaleadejumobi6624 7 лет назад +3

    beautifully illustrated 👍👍

  • @sophieszedlacsek9343
    @sophieszedlacsek9343 4 года назад +1

    Amazing Video! Great explanation, fine animation and an interesting sound. I absolutley loved it!

  • @lalkrimova3530
    @lalkrimova3530 4 года назад +2

    Thank you for the amazing video 👏🏻
    but where is the lectin pathway ? :(

  • @LaraBiebs79
    @LaraBiebs79 Год назад

    perfect video!! but you must to talk about the lectin pathway

  • @kailazhong1010
    @kailazhong1010 6 лет назад +2

    So great! Thank you!

  • @TheMiniWumbo
    @TheMiniWumbo 3 года назад +1

    so helpful

  • @chamnguyen5949
    @chamnguyen5949 4 года назад +1

    It's very helpful for me. Thank you

  • @omar23994
    @omar23994 4 года назад +1

    Wonderful explanation thanks

  • @Yaarghhhh
    @Yaarghhhh 4 года назад

    I understand now... I truly understand...

  • @charlespendragon1742
    @charlespendragon1742 5 лет назад

    Thank you very much! The video helps me a lot!!! Love you!

  • @magnificentrays133
    @magnificentrays133 Год назад

    Amazing video, thanks

  • @karimali9491
    @karimali9491 5 лет назад +1

    The best Explanation

  • @STAYPHOCUSEDFWC
    @STAYPHOCUSEDFWC Месяц назад

    This was such a good help

  • @そよ風ナシマ
    @そよ風ナシマ 3 года назад +1

    Very clear ! Thank youuu

  • @michaelb1785
    @michaelb1785 3 года назад

    Great video. First view, 99 to go before its common knowledge!

  • @futureearsnosethroatsurgeon
    @futureearsnosethroatsurgeon 3 года назад +1

    C4bC2b is the updated C3 convertase.

  • @savemeows
    @savemeows Год назад

    This was directly sent from GOD to save me from my downward spiral in complent hell!!!!!

  • @renjurajan5023
    @renjurajan5023 6 лет назад +1

    Super animation
    So easy to understand👍👌

  • @gotohemp
    @gotohemp 7 лет назад +3

    where does the c5b come from in the last step if it initially formed a complex with c3bBbc3b, does c3bBbc3bc5b continue to cleave c5's?

    • @aritrachowdhury6512
      @aritrachowdhury6512 7 лет назад +3

      I had the same question after watching this video, but the answer is yes the c5 complex continues to cleave c5

  • @mukosimukena9084
    @mukosimukena9084 6 лет назад +3

    Incredible it has made me under complement system. Thank you

  • @sarasettou6717
    @sarasettou6717 4 года назад +1

    Thank you so much 👏

  • @MotivativeAlakh793
    @MotivativeAlakh793 4 года назад +1

    Waw clear explanation 😊 thank you so much

  • @justafrog9054
    @justafrog9054 2 года назад

    The music is awesome

  • @ItachiAmiraLucy
    @ItachiAmiraLucy 6 лет назад +2

    beeeest video eveeer thank you so muuuuuuuch omg perfection

  • @agustinbalabani4547
    @agustinbalabani4547 5 месяцев назад

    Very nice video! BTW what is factor H?

  • @muhammadburhan9520
    @muhammadburhan9520 4 года назад +1

    U have made this dry topic so interesting by the grace of Allah

  • @nurlanselimov
    @nurlanselimov 4 года назад

    Təşəkkürlər👍🏻👍🏻

  • @yasminfathy7762
    @yasminfathy7762 7 лет назад +5

    Amaaazing video thank you very much

  • @mahmoudsaif7078
    @mahmoudsaif7078 Год назад

    helpful videos ...thanks

  • @abir7662
    @abir7662 Год назад

    سبحان الله في خلقه شؤون❤

  • @innate-videos
    @innate-videos 5 лет назад +1

    it would be good if you initially provided a simple overview of what the complement system is and does so that that description can be thought about as the detail is unfolded. its all detail and no overview of where that detail is going.

  • @meryemlahbara9669
    @meryemlahbara9669 6 лет назад +2

    You are amazing .... Thank you 😍

  • @darthvador3753
    @darthvador3753 6 лет назад +22

    Great animation, wish they could have picked better music than 80's sci-fi.

  • @مسلمرستمزوراب
    @مسلمرستمزوراب 4 года назад

    Thank you for your help. We need video about mannan lactin pathway pleace 🙂

  • @jamesatkinson4360
    @jamesatkinson4360 3 года назад

    Thank you!!

  • @mattboi5554
    @mattboi5554 6 лет назад +7

    The C3 convertase complex is actually composed of C4b and 2b, not 2a
    it would be C4b2b

    • @KebertXela3000
      @KebertXela3000 6 лет назад +1

      Totally see where you're coming from, but it's technically not wrong because what researchers thought was C2a was actually C2b if that makes sense. They're also interchangeably used in the literature

    • @MatthewRodGan
      @MatthewRodGan 6 лет назад

      Thanks

    • @blackV199
      @blackV199 5 лет назад

      Its actualy a c2a not b the video is not wrong

  • @batoolsamen7165
    @batoolsamen7165 7 лет назад +4

    So perfect 🤓
    Thanks ❤

  • @Angelo-Rules
    @Angelo-Rules Год назад

    I would love to see the the lectin pathway

  • @jordanseke8618
    @jordanseke8618 2 года назад

    I've seen other sources that state that C2b binds to C4b instead of C2a. Can you confirm whether this is true or not.

  • @RabinowitzRoy
    @RabinowitzRoy 7 лет назад +1

    Thanks! this video helps a lot!!

  • @amirzamani1192
    @amirzamani1192 5 лет назад +1

    Thank you soooo much!

  • @alexanderdiederichs7332
    @alexanderdiederichs7332 3 года назад

    wow thats so nice! Cool!

  • @yellowbird8037
    @yellowbird8037 6 лет назад

    Thank you so much for this explaination , even that my studies are in french but i got it all now better than how my proffessor explained it lol

  • @Guri.sk.3006
    @Guri.sk.3006 Год назад

    Awesome thanks sir

  • @kf_uthman237
    @kf_uthman237 6 лет назад +3

    Incredible, that activation of c3 convertase I.e c3bBb in alternative pathway amplified insoluble c3b to attach to the active surface of microbe, so there would be a lot of c3b on active surface..... Is that the mechanism of opsonization??? Need urgent answer

  • @anasheed1
    @anasheed1 2 года назад +1

    Why am I learning this in dentistry

  • @urwaimran1487
    @urwaimran1487 4 года назад

    Thank you

  • @fatmaahmed3963
    @fatmaahmed3963 5 лет назад +1

    Great video ..it helps imagination 😍

  • @shreyagupta983
    @shreyagupta983 6 лет назад +12

    THIS VID SAVED MY LIFE 😂

    • @TheGhost-lm1xp
      @TheGhost-lm1xp 5 лет назад

      RUclips videos at all saved my life 😂🤣