Cinthia Lizeth Not true. All literature uses 2a. Abbas, in his Basic Immunology book several years ago, tried to make this change but went back to the 2a designation.
Interesting, this video said that the small pore allows water, ions and small molecules into the cell for lysis. While my lecture notes say that the small pore formed causes the contents of the cell to spill out
Probably depends on the osmotic pressures and solubilities of stuff both inside and outside the cell, which will determine whether water will go in or pour out.
it would be good if you initially provided a simple overview of what the complement system is and does so that that description can be thought about as the detail is unfolded. its all detail and no overview of where that detail is going.
Totally see where you're coming from, but it's technically not wrong because what researchers thought was C2a was actually C2b if that makes sense. They're also interchangeably used in the literature
Incredible, that activation of c3 convertase I.e c3bBb in alternative pathway amplified insoluble c3b to attach to the active surface of microbe, so there would be a lot of c3b on active surface..... Is that the mechanism of opsonization??? Need urgent answer
That background music took me to the early 90s. Thanks for that!
words arent enough to express how thankful i am
My Immunology course is currently ripping me to pieces and this video gave me a sliver of hope.
HMX Immunology?
3APNHA its a branch of medicine
@@andrelomedico1473 not of my business, but she's asking whether she's asking immunology course on Harvard (HMX) or not.
ها بشري نجحتي لو لا
@@alialrubaie8905 صارلها ٤ سنين اكيد نجحت😹
This was the ONLY demonstration that made me finally understand the complement system paths!!!! Thank you sooooo much!!!!!
you guys need to make more videos like these! they are super helpful!
You’re the real MVP for making this!!!
Incredible! this teaches me about how my body works, and helps me understand the immune system in my body. Thank you very much.
Samuel Mashabela are u a 5 year old?
Samuel Mashabela ok mon
Thank you sooooooo much........this just saved a whole ass unit in immuno.
final exam tomorrow and i really feel like i learn better from videos like this and is perfect when you want a quick summary to complement your notes.
This is the definition of perfection.
Perfect video!! Thank you for being so thorough! Maybe I won't fail my first immunology test after all! lol
Quite amazing! thank you so much, now i can get back to my immunology course, and will certainly understand it, for once.
This was a great video and really helped me understand the concept. Thank you so much and Please make more such videos
Most helpful video in the universe ❤️❤️❤️❤️❤️ wish everything was explained like this
Great detail of explanation with superb animation
Bring more of such videos
Thankyuhh very much for such fantastic illustration!!!! Now i get to know way better than how my professor taught!!
Beautifully explained and illustrated.
You diamond. My lecturer couldn't explain this at all. Thanks x
I love this video Soo much
I will like another one like on T and B lymphocytes
That video makes the complement system simple
Thank you for this wonderful video 🙏
Wow I'm grateful.
It's never been this easy. I can't thank you enough
God bless you for this
C2b+C4b is the C3 convertage as I know.
This is ridiculously good, THANKYOU
Very informative and also amazing way to understand complement pathway thank you so much 😊☺️
Thank you so much for this
thank you so much for this life saving video.
Thank you so much, this video is so helpful.
Fantastic! Very helpful video. Thank you!
thank you for giveing us a clear vesion to keep in mand about complement,, algerian pharmacy student here ^^ thank you brother
very well explained. thank you so much you are a life saver
Highly appreciated
Thumbs up . keep it up
This helps so much! Great explanation and animation!
عظيم ..شكراً لجهودكم
historically the larger fragment of C2 was called C2a but is now referred to as C2b ****
Cinthia Lizeth
Not true. All literature uses 2a.
Abbas, in his Basic Immunology book several years ago, tried to make this change but went back to the 2a designation.
@@raheelshafi882 however it's used used by major scientists in the field, e.g. Daniel Ricklin
Interesting, this video said that the small pore allows water, ions and small molecules into the cell for lysis. While my lecture notes say that the small pore formed causes the contents of the cell to spill out
Probably depends on the osmotic pressures and solubilities of stuff both inside and outside the cell, which will determine whether water will go in or pour out.
I have no idea what this is but it is interesting
This is so good!!! thank you so much!!
Superb explanation, thank you!
Great video! Thank you!!
Wonderfully explained
I love it I understand the complement system finally 🙌 thanks 😊
Finally Immunology seems a little bit easier!
Amazing and extremely clear explanation. Great animation👍👌
Amazing video!
beautifully illustrated
Thanku sir for this helpful video.I'm from India
Thank your sooo much... Excellent very,,,, معهد الدكتور أمين ناشر اثبتوووو وجودكم 👨💼👨🔬. 👨🦱 ومن يتهيب صعود الجبال يعيش طول الدهر بين الحفر
are c3a and c5a opsonin molecules?
beautifully illustrated 👍👍
Amazing Video! Great explanation, fine animation and an interesting sound. I absolutley loved it!
Thank you for the amazing video 👏🏻
but where is the lectin pathway ? :(
perfect video!! but you must to talk about the lectin pathway
So great! Thank you!
so helpful
It's very helpful for me. Thank you
Wonderful explanation thanks
I understand now... I truly understand...
Thank you very much! The video helps me a lot!!! Love you!
Amazing video, thanks
The best Explanation
This was such a good help
Very clear ! Thank youuu
Great video. First view, 99 to go before its common knowledge!
C4bC2b is the updated C3 convertase.
This was directly sent from GOD to save me from my downward spiral in complent hell!!!!!
Super animation
So easy to understand👍👌
where does the c5b come from in the last step if it initially formed a complex with c3bBbc3b, does c3bBbc3bc5b continue to cleave c5's?
I had the same question after watching this video, but the answer is yes the c5 complex continues to cleave c5
Incredible it has made me under complement system. Thank you
Thank you so much 👏
Waw clear explanation 😊 thank you so much
The music is awesome
beeeest video eveeer thank you so muuuuuuuch omg perfection
Very nice video! BTW what is factor H?
U have made this dry topic so interesting by the grace of Allah
Təşəkkürlər👍🏻👍🏻
Amaaazing video thank you very much
Hla
helpful videos ...thanks
سبحان الله في خلقه شؤون❤
it would be good if you initially provided a simple overview of what the complement system is and does so that that description can be thought about as the detail is unfolded. its all detail and no overview of where that detail is going.
You are amazing .... Thank you 😍
Great animation, wish they could have picked better music than 80's sci-fi.
Thank you for your help. We need video about mannan lactin pathway pleace 🙂
Thank you!!
The C3 convertase complex is actually composed of C4b and 2b, not 2a
it would be C4b2b
Totally see where you're coming from, but it's technically not wrong because what researchers thought was C2a was actually C2b if that makes sense. They're also interchangeably used in the literature
Thanks
Its actualy a c2a not b the video is not wrong
So perfect 🤓
Thanks ❤
I would love to see the the lectin pathway
I've seen other sources that state that C2b binds to C4b instead of C2a. Can you confirm whether this is true or not.
Thanks! this video helps a lot!!
Thank you soooo much!
wow thats so nice! Cool!
Thank you so much for this explaination , even that my studies are in french but i got it all now better than how my proffessor explained it lol
Awesome thanks sir
Incredible, that activation of c3 convertase I.e c3bBb in alternative pathway amplified insoluble c3b to attach to the active surface of microbe, so there would be a lot of c3b on active surface..... Is that the mechanism of opsonization??? Need urgent answer
Yes !!
Why am I learning this in dentistry
Thank you
Great video ..it helps imagination 😍
THIS VID SAVED MY LIFE 😂
RUclips videos at all saved my life 😂🤣