Tiny Bombs in your Blood - The Complement System

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  • Опубликовано: 27 июл 2019
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    One of the key players of our immune system is the complement system. An army of millions and trillions of tiny bombs, which work together in a complex and elegant dance to stop intruders in your body.
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Комментарии • 16 тыс.

  • @kurzgesagt
    @kurzgesagt  2 года назад +1055

    You can now preorder the Kurzgesagt Immune System book! “IMMUNE - A Journey into the Mysterious System That Keeps You Alive”: kgs.link/ImmuneBook
    IMMUNE is a fascinating and fun journey through your own body, where we’ll be exploring mystery organs, murder universities, your enemies from viruses, bacteria and cancer (and how your immune system might have killed a cancer cell while you were reading the last few sentences) and the incredibly beautiful and amazing parts, cells and systems that keep you alive. After reading it you should not only gain a new appreciation for your own body but also experience disease differently. Also 45 illustrated pages by the Kurzgesagt team make the book very pretty.

  • @BD0G
    @BD0G 4 года назад +20450

    “Many mindless things can do smart things together”
    Me and the boys

  • @grizzZlyBear
    @grizzZlyBear 4 года назад +7686

    Superhero: I keep people safe.
    C3b: hold my C3a

    • @Greenomb
      @Greenomb 4 года назад +186

      You deserve an award

    • @rdkonevrd9898
      @rdkonevrd9898 4 года назад +219

      that's some 4D chess move right there

    • @bartij9830
      @bartij9830 4 года назад +15

      nice

    • @christopherg2347
      @christopherg2347 4 года назад +62

      But isn't the C3a technically the "Bat Signal" for the superhero team called "The Immune System"?

    • @charankko4142
      @charankko4142 4 года назад +47

      Dude this the most *microscopic* joke I heard and TQ for that

  • @lostmusic99
    @lostmusic99 2 года назад +562

    "Many mindless things can do smart together"
    *APE TOGETHER STRONK*

  • @techadox3821
    @techadox3821 2 года назад +669

    It's very difficult to put in words how motivating this is for me as a med student who's lost lots of my initial drive because of my university's covid coping mechanisms. The complementary system was an especially hard lesson for me to understand considering the absurd amount of random letters and numbers I've had to memorize. Really, thank you for sparking the motivation in me again.

    • @FutureCommentary1
      @FutureCommentary1 2 года назад +34

      Thanks for choosing medecine. Hang in there you are doing something valuable for yourself and for the world.

    • @shamus-moore
      @shamus-moore 11 месяцев назад +3

      @@abirdpilguy3211 "fuck is this algebra or some shit"

  • @populistprime2581
    @populistprime2581 4 года назад +1846

    1:56 So basically, my immune system is powered by Tetris?
    *...awesome.*

    • @BBBBBBBBBBBBBBBB2
      @BBBBBBBBBBBBBBBB2 4 года назад +35

      *tetris beatbox*

    • @fighteer1
      @fighteer1 4 года назад +50

      It’s kind of like that for all proteins. Even more important than the chemical properties are the geometric properties. Our bodies and indeed all living organisms are based on this principle. So yes, you could say that life is a ridiculously over complicated game of Tetris.

    • @altf4undo01
      @altf4undo01 4 года назад +13

      John Aldrich Well, life and the universe at large is always trying to make some sort of order out of chaos, and the gameplay of Tetris reflects that. So basically, EVERYTHING is an elaborate game of Tetris.

    • @hawkmen9298
      @hawkmen9298 4 года назад +6

      Looks like doctor Mario wasn't that far off

    • @ok5988
      @ok5988 4 года назад

      That's funny boi 😂👌

  • @baodau2230
    @baodau2230 4 года назад +1750

    "Imagine being covered in flies. Now imagine them turning into wasps."
    I'd rather not, thanks.

  • @TheAdvertisement
    @TheAdvertisement 2 года назад +372

    Brain: _Send in the nukes._
    Heart: But... there's too many innocent cells in the area! There will be millions of casualties!
    Brain: JUST DO IT!

    • @zaytaz9331
      @zaytaz9331 2 года назад +5

      Wait, what? Why would the heart say that

    • @TheAdvertisement
      @TheAdvertisement 2 года назад +40

      @@zaytaz9331 It controls the bloodstream and therefore if it has some kind of self-awareness would be associated with what the immune system's doing.

    • @zaytaz9331
      @zaytaz9331 2 года назад +3

      @@TheAdvertisement hmm, yes I guess you're right but I think a cell (helper T cell) would be the brain you said and the heart maybe the dendric cell, I'm still new to biology tho :)

    • @TheAdvertisement
      @TheAdvertisement 2 года назад +4

      @@zaytaz9331 I wasn't putting that much thought into it.

    • @atulecho
      @atulecho 2 года назад +1

      The hearts job is too pump blood

  • @erik69006
    @erik69006 2 года назад +150

    As a microbiology student with long stressful hours of preparing for immunology exams I can not recommend this enough. It's an amazing video to truly understand the big picture and then learn the proteins involved in it.

  • @mexicanjojo6369
    @mexicanjojo6369 4 года назад +814

    Knowing that I'm basically a perfectly oiled giant moving fortress with thousands of defence mechanisms makes me feel pretty badass

  • @lemongrass5636
    @lemongrass5636 4 года назад +1738

    Kurzgesagt : "Imagine the flies turn into wasps"
    Bacteria : END ME
    .

  • @greek-god
    @greek-god 2 года назад +61

    POV: You just watched the first episode of IMMUNE, clicked on part two, and are just now realizing this video is from two years ago.

  • @canadoodlez5009
    @canadoodlez5009 2 года назад +19

    “Complements to the chef”
    **muffled explosion noises**

  • @songbirdrohan3973
    @songbirdrohan3973 4 года назад +1993

    "Today's sponsor is you"
    never felt so special in my life before

    • @jenlaura3003
      @jenlaura3003 4 года назад +42

      same. I can't describe why i felt so touched when he said that

    • @rabeebibrat1805
      @rabeebibrat1805 4 года назад +6

      same here

    • @batuhandag3354
      @batuhandag3354 4 года назад +6

      Same

    • @ReyahsCommet
      @ReyahsCommet 4 года назад

      Vayne Carudas Solidor I’m watching ads. You’re welcome d(^0^d)

    • @misakamikoto8785
      @misakamikoto8785 4 года назад +1

      @Vayne Carudas Solidor But by viewing this video, you increased the view count by 1, which increases their income.

  • @UnintelligibleYT
    @UnintelligibleYT 4 года назад +6030

    "Imagine you are covered in flies"
    Oh no I don't like this
    "Imagine you are covered in flies, but now they're wasps"
    OH NO NO NO

  • @erdub84
    @erdub84 2 года назад +14

    This video makes me want to cry at the massively complex such a beautiful system is.

  • @MossyMozart
    @MossyMozart Год назад +56

    As someone who gets quickly lost talking to immunologist, I appreciate your videos. The immune system is so complex to me that when I think I has grasped one concept, there is another figure out, like an onion with infinite payers. I am also very visual, so you have that aspect of learning covered, too. I am interested in reading your book, "Immune: A Journey into the Mysterious System That Keeps You Alive", too. Thank you for also including a family-run business like Powell's City of Books to sell it through.

    • @BeingForeverBroken
      @BeingForeverBroken Год назад

      I ordered the book because I also really want to read it but I've read several reviews complaining that there were like 3 illustrations and it was more like a textbook. In case you were hoping it was more like their videos

    • @timoteusfeik5851
      @timoteusfeik5851 Год назад

      ​@@BeingForeverBroken idk if u have the book already, but i bought it like 6 months ago and it is full of illustrations. Readable, informative and gorgeous, a worth buy!

    • @BeingForeverBroken
      @BeingForeverBroken Год назад

      @@timoteusfeik5851 I do have it now and I agree with the commenters that it's more like a textbook than a picture book, still need to read it to say anything about it, but happy to have it nonetheless!

  • @NesirahGanks
    @NesirahGanks 4 года назад +718

    "Imagine those thousands of flies turn into wasps"
    me:(confused screaming)

    • @medexamtoolsdotcom
      @medexamtoolsdotcom 4 года назад +12

      Man I hate it when that happens. When I get covered by thousands of flies and then they all turn into wasps and start stinging my eyeballs that is. It's super annoying.

    • @moogobIin
      @moogobIin 4 года назад +1

      THERE IS A STUNNING LACK OF B E E S IN THIS SITUATION! A COUPLE OF BEES SHOULD FIX THIS
      “AAAAA! MY SITUATION HAS ONLY BE WORSENED BY THE ADDITION OF YET *MORE BEES!*”

    • @shadow1182
      @shadow1182 4 года назад

      Now imagine that they call over their friends to start drilling/boring through your skin...

    • @Ett.Gammalt.Bergtroll
      @Ett.Gammalt.Bergtroll 4 года назад +1

      Moo King STAND STILL! DONT MOVE AS MY BRIEFCASE FULL OF BEES WILL PUT A STOP TO THIS NUISANCE.

    • @Na-ky9mo
      @Na-ky9mo 4 года назад +1

      U shouldve done it like this
      me: *confused screaming*

  • @Storethis
    @Storethis 4 года назад +2680

    *imagine you are covered by thousands of flies*
    No, I don't think I will

    • @OMGpandemic
      @OMGpandemic 4 года назад +56

      It gets worse.

    • @orik737
      @orik737 4 года назад +127

      Now imagine those flies turn into wasps

    • @alkureshi
      @alkureshi 4 года назад +6

      How about worms then?

    • @sammyboyroute
      @sammyboyroute 4 года назад

      Pls do this

    • @Storethis
      @Storethis 4 года назад +6

      @@alkureshi a little better but still imma have to decline

  • @cwejter
    @cwejter 2 года назад +14

    i love how under every video people always speak in memes. I'm so proud of this community

  • @yvindHyland
    @yvindHyland 2 года назад +34

    In the bacterias defense, they were just hanging out when you clumsily cut yourself on their home and now they're getting covered in "wasps".

    • @EvilGears
      @EvilGears 2 года назад +1

      Well of course most bacteria are actually harmless, but the ones that are harmful sure can kill you if nothing is done about it. Because our immune systems can not distinguish harmful bacteria from harmless, all they can do is try to leave no one alive.

    • @polarbear6479
      @polarbear6479 2 года назад +2

      @@EvilGears so...... the human body is xenophobic for our safety

    • @theshermantanker7043
      @theshermantanker7043 2 года назад +1

      @@polarbear6479 Not entirely true, Innate Immune Cells can sometimes tell harmless from harmful

  • @mimi2011tiger
    @mimi2011tiger 4 года назад +1080

    'thousands of them flood away from the site of battle screaming for attention'
    relatable content wow

    • @cardiaccoder9622
      @cardiaccoder9622 4 года назад +6

      mimi2011tiger. A shamefur dispray

    • @juntingiee2602
      @juntingiee2602 4 года назад +11

      ArEa 51

    • @Alaerick1
      @Alaerick1 4 года назад +4

      Flashback to pewdiepie vs t series

    • @mattfromwiisports7780
      @mattfromwiisports7780 4 года назад +3

      Or the French

    • @etiennecouture1552
      @etiennecouture1552 4 года назад +4

      For most of it's history, France was one of the greatest military powers in Europe. Yes, over the last 200 years or so you see a fair amount of French defeats, but you can't say they would ''flood away from the site of battle screaming for attention''.

  • @alexgonzales248
    @alexgonzales248 4 года назад +783

    "A beautiful example of how many mindless things can do smart things together."
    >Any group assignment with my friends.

    • @gearandalthefirst7027
      @gearandalthefirst7027 4 года назад +18

      I wanna meet your friends, my group's motto would be "A beautiful example of how many mindless things can forget what they were supposed to be doing and start blasting Manson at the prudish neighbors"

    • @Dark_Slayer3000
      @Dark_Slayer3000 4 года назад +2

      Or the nerve cells in your brain

    • @adualaispuro
      @adualaispuro 4 года назад +1

      Emergence

    • @javagroup6587
      @javagroup6587 4 года назад

      @ WTF!!! You Just Give A Worst Nuke Code

    • @withclass2178
      @withclass2178 4 года назад +2

      @ Why? Just... why? You just gave the code for depression, why would you do such a thing?

  • @gamingsandbox5483
    @gamingsandbox5483 2 года назад +61

    As a science student, it's absolutely incredible what the human body immune system does so silently as we just live our normal lives.

  • @ariadneschild8460
    @ariadneschild8460 Год назад +3

    The complement system rips holes in things until they die, I love this show.

  • @jonathanperez4930
    @jonathanperez4930 4 года назад +3596

    “Imagine being covered by flies”
    “Oh no”
    “Now imagine them turning into wasps”
    “NO”

    • @lotgc
      @lotgc 4 года назад +106

      _panic_

    • @simply.complex
      @simply.complex 4 года назад +54

      Aw helll nooo!!!

    • @Cosiek7
      @Cosiek7 4 года назад +34

      Imagine feeling sympaphy for mindless proteins that trie to kill you every day...

    • @11atron
      @11atron 4 года назад +23

      Seriously trying to give me a panic attack

    • @randomstone9485
      @randomstone9485 4 года назад +26

      Now *guns*

  • @jacktheflying
    @jacktheflying 4 года назад +697

    "Imagine being covered in flies again"
    I'd rather not
    "Now, imagine them turning into wasps"
    I'D RATHER NOT

    • @Anintora
      @Anintora 4 года назад +19

      I pictured that in my head and now I want to die

    • @F.R.E.D.D2986
      @F.R.E.D.D2986 4 года назад +1

      lol

    • @jozsefkalmar7054
      @jozsefkalmar7054 4 года назад +24

      Now the wasps have alerted a bunch of snakes to cover you. A bear drags you off to a nuclear sub (it's a former KGB bear) that dumps you in shark-infested waters. The planktons clear up any remains of you and in turn are swallowed by whales.

    • @siva_yt_v3.0.1
      @siva_yt_v3.0.1 4 года назад

      🤣😂😂😂🤣🤣🤣🤣

    • @alfinpovg6378
      @alfinpovg6378 4 года назад

      @@jozsefkalmar7054 😃😆😆😂lol

  • @JordanBeagle
    @JordanBeagle 2 года назад +111

    Presumably you've already thought of this, but I'm curious to see a video on what happens when the immune system is overwhelmed and the cut becomes majorly infected and you have take antibiotics, that would be really interesting

    • @cockatoo010
      @cockatoo010 Год назад +25

      Most common antibiotics are not bactericidal, but bacteriostatic, this means that they don't kill bacteria, but they prevent them from reproducing. In the end the infection will be taken care of by the immune system but the presence of antibiotics is a massive help.
      This is also why you don't interrupt your antibiotic treatment as soon as you feel better, if you do, you are allowing the static bacterial population to once again begin reproducing and this will hurt your immune systems chances. Even more because when you feel bad and restart the antibiotics, the bacteria will have adapted and developed resistance!
      I do agree that this would be a good addition to the immunology series from this channel!

    • @adrianfrutos7357
      @adrianfrutos7357 8 месяцев назад

      100th loke

  • @nadiahudson7331
    @nadiahudson7331 2 года назад +8

    I fucking love this channel. As a nursing student it teaches me things my teachers can’t explain very well, I love learning.

  • @Sillybutts
    @Sillybutts 4 года назад +2720

    "imagine being covered in flies" no thanks.
    "Now they are wasps" why do you hate us?

    • @AvsJoe
      @AvsJoe 4 года назад +130

      I was expecting a third one. "Now imagine the wasps are tarantulas."

    • @alexandersebela370
      @alexandersebela370 4 года назад +7

      Then leave this channel to normal people. I know you're trying sound funny but it's stupid, if you can't be grateful for this free education find another channel thanks.

    • @raymond4955
      @raymond4955 4 года назад +81

      @@alexandersebela370 r/whoooosh

    • @sinoskopyasky
      @sinoskopyasky 4 года назад +59

      @@alexandersebela370 wtf they were joking

    • @medic5258
      @medic5258 4 года назад +6

      Ohh its a little hoovy :3

  • @prelawnoob
    @prelawnoob 3 года назад +5376

    "The complement system does 3 things"
    1.Crippling
    2.Activating
    3. *rip and tear until it's done*

    • @yurger9295
      @yurger9295 3 года назад +124

      **SOS from Earth**

    • @fuzeulqadir
      @fuzeulqadir 3 года назад +81

      and the doom guy helps with 3

    • @nazarsukkar5809
      @nazarsukkar5809 3 года назад +64

      Lmao holyshit so true. Hmm maybe that's why i feel batter when i listen to doom ost when iwas sick with covid naaa it's probably because of the adrenaline

    • @masterzoroark6664
      @masterzoroark6664 3 года назад +96

      Doom, but it's Cells At Work

    • @bdorsey19
      @bdorsey19 3 года назад +11

      Isn’t there a glory kill in eternal where you break a demons legs/immobilize it and slice it’s em head off with the blade?

  • @bean40
    @bean40 2 года назад +11

    “The problem is, that in a war both sided adapt.”
    So it’s basically like how in movies the villain has a super smart evil plan, but the hero is even smarter, then the villain gets an even SMARTER plan, but the hero gets even smarter again, and again, and again.

  • @fushi7853
    @fushi7853 6 месяцев назад +3

    Studying medicine is demanding and can get boring sometimes when you've been studying everyday for months .It is videos like this that keep my passion alive and fuel it even more . Thank you so much

  • @XenonKresnik
    @XenonKresnik 4 года назад +478

    Kurzgesagt: "A beautiful example of how many mindless things can do smart things together"
    *Apes together strong*

    • @pranveersingh3662
      @pranveersingh3662 4 года назад +1

      Haha I remember 😂😂 that 😂 one 😂

    • @mrboobiesrider9212
      @mrboobiesrider9212 4 года назад +6

      Just like redditors

    • @ryandavis4689
      @ryandavis4689 4 года назад

      Awesome...good quote.

    • @69op2gg1005ify0m
      @69op2gg1005ify0m 4 года назад

      Our brain is the same way. Buncha mindless dendrons accepting electric signals...result = our current civilisation

    • @neron0va
      @neron0va 4 года назад

      i was thinking the same thing!

  • @calmkat9032
    @calmkat9032 4 года назад +7855

    Kurzgesagt: "Imagine being covered in flies"
    Me: "No"
    Kurzgesagt: "Do it again"
    Me: "Stop"
    Kurzgesagt: "W A S P S"

  • @louannaj7645
    @louannaj7645 2 года назад +15

    This series with the immune system is the best one i have come across so far.. This one exactly brought back memories of my uni final year project- which was on the complement system. Great job guys

  • @MuletTheGreat
    @MuletTheGreat 2 года назад +6

    This playlist started with the Bacterial infection video.
    The jump in quality and detail of the animation is INCREDIBLE. Even the voice over sounds like he's practiced hard.
    What a wonderful channel. :)

  • @Agent-00F
    @Agent-00F 4 года назад +2123

    "tiny bombs in your blood"
    - Airport security intensifies

    • @sharonong8845
      @sharonong8845 4 года назад +9

      Undercover noob lololololol😂😂😂😂😂

    • @TheRecklessBravery
      @TheRecklessBravery 4 года назад +1

      Undercover noob i dont get it.

    • @okman7933
      @okman7933 4 года назад +9

      Dustotom2007’s Animations
      I’m guessing you’re not American, or French or British or whatever. Bombs use to be a problem in airports.

    • @TheRecklessBravery
      @TheRecklessBravery 4 года назад +3

      @@okman7933 im italian.

    • @TheRecklessBravery
      @TheRecklessBravery 4 года назад +1

      Aslong i know in italy we never had bomb in airports.

  • @zblouite3336
    @zblouite3336 4 года назад +2855

    Now i want an RTS-game based on our immune system.

    • @Dero_Zero
      @Dero_Zero 4 года назад +99

      That's what I was thinking too lmao

    • @wh173
      @wh173 4 года назад +187

      Those would be great for schools

    • @ok_listen
      @ok_listen 4 года назад +31

      Thank you, now i need this

    • @emilealpha2392
      @emilealpha2392 4 года назад +29

      Bruh the whole time I was thinking halo wars

    • @notmyrealname6040
      @notmyrealname6040 4 года назад +72

      I know a game that revolves around being a cell, it has self defense game mechanism but it's about a single cell not the whole immune system. It's called Cell Craft.

  • @hedera1332
    @hedera1332 2 года назад +7

    Watching these videos have played a major role in getting me interested in the immune system and biomedical science. I am now back here watching this video again as a biomedical science student who has just started studying the immune system at university and these videos are still super helpful, so thanks guys!

  • @k_1ng_
    @k_1ng_ 2 года назад +3

    Never thought I would be so interested in this stuff!! You make everything interesting, this channel is way too underrated!

  • @americaneggroll2496
    @americaneggroll2496 4 года назад +834

    Kurzgesagt: Your body is filled with countless, tiny bombs
    Airport Security: Say sike right now

    • @farzadedition6969
      @farzadedition6969 4 года назад +6

      American Eggroll haha

    • @ls200076
      @ls200076 4 года назад +5

      To to liberate your body timmy

    • @rommyjoj326
      @rommyjoj326 4 года назад +13

      *your body is filled with countless water bottles

    • @ajollyduck
      @ajollyduck 4 года назад +5

      You: has many tiny bombs inside you. Anti-terrorist forces: say sike right now.

    • @josiahj6967
      @josiahj6967 4 года назад +2

      Probably the best one I've seen so far🤣🤣🤣😂😂

  • @Franco00007
    @Franco00007 4 года назад +1375

    Goes to 7:34
    "This video was sponsored by you"
    *sniffs* you make me cry of joy ;^;

  • @gustavohenke
    @gustavohenke 2 года назад +1

    Having read your book and then watch this video makes a lot of things that were unclear, clearer. Thanks!

  • @user-ev6bw2ch3s
    @user-ev6bw2ch3s 2 года назад +4

    医学部生なんですが、この動画を先週の免疫系試験の前に見たかった、、、めちゃくちゃわかりやすい、、、

  • @volcano12100
    @volcano12100 4 года назад +793

    As a medical student, complement is one of the the most elaborate and complex topics of Immunology, literally, you just want to sit and cry while studying it, thanks for showing it to the world, getting the most important points in the form you do.

    • @rasendori9
      @rasendori9 4 года назад +9

      Same here! I took my boards last month, and I only wish I could have used this as a reference.

    • @nintee9877
      @nintee9877 4 года назад +3

      I love these videos :)

    • @SaftoRangen
      @SaftoRangen 4 года назад +13

      Well, since you seem to have insights on this topic, is there anything you'd want to add to this video that Kurzgesagt had to leave out? Or would you say that this is pretty much a perfect summary of how the Complement System works?

    • @kingsloth4106
      @kingsloth4106 4 года назад +4

      Is the summary accurate? Is there a way to make our complement system more effective?

    • @PurpleH4z3
      @PurpleH4z3 4 года назад +1

      I dont know, just learning how it works is not thaaaaat hard, not the thing you are going to suffer more while studing

  • @TheRandomizerYT
    @TheRandomizerYT 4 года назад +1344

    *_You expected that I will overlook the improved animations and graphics...?_*
    OMG Thank you for the likes guys...
    And obviously hands off to the animators... Great job😉

    • @dragon67849
      @dragon67849 4 года назад +38

      But it was I DIO?

    • @Kerosiin
      @Kerosiin 4 года назад

      Yes because they were amazing before too ❤️

    • @ovencake523
      @ovencake523 4 года назад +3

      My complements to the animators!

    • @hardiksharma5441
      @hardiksharma5441 4 года назад +7

      Was that a motherfucking!!! JOJO'S reference ?

    • @Gamer_Tanks
      @Gamer_Tanks 4 года назад

      @@DetectiveLevi HOLY MILK

  • @FoxMonkey-xw5yf
    @FoxMonkey-xw5yf 2 года назад +7

    NANOMACHINES, SON

  • @taleiforrest1714
    @taleiforrest1714 Год назад +2

    Complement is one of those topics that I've always been terrified of - this video makes learning about it so much more approachable! Thank you!

  • @taeisyoung7722
    @taeisyoung7722 4 года назад +2995

    this would be such a cool concept as a game, where you can play on the bacteria/virus side or human side.

    • @SirFaceFone
      @SirFaceFone 4 года назад +152

      Kind of like Spore

    • @zsoltlengyel9085
      @zsoltlengyel9085 4 года назад +271

      now that I think about it that's a decent idea. It would basically be a more complex war game without food or politics. It would have massive armies specialized to take on only certain enemies and if you forget a single part of the immune system like say killer T cells your army falls apart for 1 reason or the other or does worse in the long run like if you did not make any memory T cells.
      You would like colony survival.

    • @gergogadget4262
      @gergogadget4262 4 года назад +62

      Yeah it can be really interesting.
      You could make your own bodies from parts and you could make how they change shapes and how they can work together.

    • @tarz0216
      @tarz0216 4 года назад +14

      It would be really cool

    • @bsantos1182
      @bsantos1182 4 года назад +37

      @@zsoltlengyel9085 even that can become politics now lol

  • @Astromaniac8802
    @Astromaniac8802 4 года назад +1148

    “Imagine being covered in thousands of flies”
    *internal screaming*
    “Now imagine the turn into wasps”
    *Confused screaming*

    • @tesorosdetinkertown8310
      @tesorosdetinkertown8310 4 года назад +28

      "Now imagine they turn into wasps"
      *N I G H T M A R E*

    • @user-mw8dz3by8v
      @user-mw8dz3by8v 4 года назад +12

      “Now imagine they turn into flying ticks”
      💀

    • @kakashiMEK
      @kakashiMEK 4 года назад +7

      *nicolas cage's head in a bucket of bees screaming gif

    • @fredrickfraser1659
      @fredrickfraser1659 4 года назад +3

      “Now imagine they turn into Horse Flies!”

    • @alicelu5691
      @alicelu5691 4 года назад +1

      imagine them fighting in front of your face...

  • @helenofnone
    @helenofnone Год назад +1

    "a beautiful example of how many mindless things can do smart things together" a ray of hope for my classmates

  • @dinohall2595
    @dinohall2595 Год назад +7

    No joke, this video that I first watched three years ago turned me on to the immune system so much I decided to write my university term paper for a cell biology course on it. I just cranked out a slightly above-mediocre paper about how the complement system is activated by drinking alcohol and contributes to alcoholic liver disease (it basically does the same things it does to the bacteria in this video but to liver cells instead). Thanks Kurzgesagt for the inspiration!

  • @asn9337
    @asn9337 4 года назад +8357

    I am a doctor and I work with patients with autoimmune disease and thinking about the complement system is a big part of the job. I have NEVER heard a clearer and better explanation about the fundamentals of how this works in my entire training. great job guys! You've gotten yourselves a new Patreon TODAY!!!

    • @naveedaman1
      @naveedaman1 4 года назад +61

      vitiligo is also an autoimmune disorder right?

    • @emmanuuell
      @emmanuuell 4 года назад +14

      Naveed Aman vitiligo gang vitiligo gang

    • @Noblewolf19
      @Noblewolf19 4 года назад +119

      Amen to that. Where was this when I was struggling to understand immunology back in college?? Lol

    • @alexadelaide
      @alexadelaide 4 года назад +38

      The cutesy drawings are aiit too

    • @benjaminnewlon7865
      @benjaminnewlon7865 4 года назад +11

      I have t1 diabetes. An autoimmune disease

  • @Neronix17
    @Neronix17 4 года назад +904

    "Many mindless things can do a smart thing, together"
    So...like a government?

    • @pedrokreutzwerle9488
      @pedrokreutzwerle9488 4 года назад +144

      I think you got the "smart" part wrong there buddy

    • @KaptenAmurika
      @KaptenAmurika 4 года назад +129

      A government is many individually smart things failing to cooperate, and thus doing dumb things.
      Because of this, they're very easy to infect by outside influences looking to get a foothold and usurp the process for personal benefit.

    • @BioHzrd0010
      @BioHzrd0010 4 года назад +31

      Many "smart" things do dumb things together.

    • @asrielcyleoroceo921
      @asrielcyleoroceo921 4 года назад

      haha, not so good

    • @ctmctm2031
      @ctmctm2031 4 года назад +12

      @Scooters Videos orange man bad

  • @collarclubchannel
    @collarclubchannel 2 года назад +1

    This is too good to skip!!!! Really love it! Thank you so much for your hard work, this is a really big nice job!

  • @TurtleSauceGaming
    @TurtleSauceGaming 2 года назад +3

    I enjoyed the complexity of this one a lot more than your other, more general immune system video. You used actual names of the compliment proteins. A great refresher from microbio! Please do more indepth immune system videos like this!

  • @harrypitts3904
    @harrypitts3904 4 года назад +1712

    this video was sponsored by... you
    :’) thanks man

    • @aromorguy
      @aromorguy 4 года назад +42

      [happy viewer noise]

    • @heyimmary1876
      @heyimmary1876 4 года назад +5

      @@aromorguy 😂😂😂😂

    • @aarfeenanees9147
      @aarfeenanees9147 4 года назад +3

      @@aromorguy lol nice one

    • @__katara__4500
      @__katara__4500 4 года назад +1

      why do we die? Why couldn't living things defeat death in their evolution? What's the difference between an old man and a baby? what if we could transfer a person's brain to someone younger than him? if each beginning has an end, can we extend the time between death and right now by transferring our brains to someone else instead of finding immortality?

    • @untergehermuc
      @untergehermuc 4 года назад

      They also get a lot of free money from the German public TV found. In the end they are a Munich based company.

  • @lotgc
    @lotgc 4 года назад +1148

    They should make an rts game based on the immune system, bacteria, and viruses.
    Like the viruses are slow and sneaky, the bacteria can strike hard and fast but take time to adapt, but the immune system is the reverse of bacteria

    • @suhdude9220
      @suhdude9220 4 года назад +56

      Micah Roberts nostalgic af. Would be like a more realistic spore game

    • @ygypt
      @ygypt 4 года назад +27

      theres one where you play AS a bacteria or virus, but its more about infecting the world on a large scale and not about the small battles that occur within bodies

    • @rime1585
      @rime1585 4 года назад +4

      Exactly what I thought

    • @lacruzdelsur2799
      @lacruzdelsur2799 4 года назад +36

      @@ygypt Oh Plague Inc, I had so good times playing it...

    • @supercat765
      @supercat765 4 года назад +13

      Well for highschool biology I did make a simple simulation game of the immune system
      where the player could do things like add cells of the few types I included and viruses
      and if you were able to start with a good balance and a bit of luck it was reasonably fun to watch the battle between the b-cells and antibodies against the viruses

  • @EmilyJelassi
    @EmilyJelassi Год назад

    I only recently found your channel, but I’m so glad I did! Thank you for making such a complex and difficult subject so much easier to understand!! 😊

  • @thespaceyvoid
    @thespaceyvoid 3 дня назад

    Your videos always uplift me to learn more about many things, be it nature, our body, or simply how the society works. The way you explain things makes it a large audience to take a grasp at the topic at the very beginning. I'm so mesmerized by the animations as well. :)

  • @saiancritic2213
    @saiancritic2213 4 года назад +506

    "This video was sponsored by you."
    I'm certain I'm in love with a RUclips channel.

  • @Edo9300
    @Edo9300 4 года назад +1055

    Everything starts when c4 is activated.
    Ops, wrong war

    • @barnetsy1
      @barnetsy1 4 года назад

      Edo9300 😂

    • @patates42
      @patates42 4 года назад +35

      Everything changed when the Fire Nation attacked.
      Ops, wrong animation

    • @StillReload
      @StillReload 4 года назад +13

      C4 is the most effective way to wipe out all the bacteria and viruses, but the it has pretty bad side effect tho

    • @Marble_Pie
      @Marble_Pie 4 года назад +6

      C4 is an actual explosive. C3 isn’t, sadly.

    • @heroslippy6666
      @heroslippy6666 4 года назад +6

      C4 is one of the safest explosives known to man kind.

  • @jasonmyneni8605
    @jasonmyneni8605 2 года назад +3

    This is an incredibly in-depth video. It was clearly written by someone who is educated in this field

  • @tiffanyfaulk9100
    @tiffanyfaulk9100 2 года назад +1

    Such a good job on this video guys! Thank you!

  • @zyadxtiger6261
    @zyadxtiger6261 4 года назад +1871

    WHEN I FEEL I AM ALONE THEN I REMEMBER MY IMMUNE SYSTEM IS PROTECTING ME

  • @Skulltroxx
    @Skulltroxx 4 года назад +1668

    Dude, even 7 minutes of your content felt like 2 minutes.
    ngl, the video quality is too good to be true!

    • @kyle6579
      @kyle6579 4 года назад +13

      And 2 minutes feels like 10 years

    • @fabiosolive
      @fabiosolive 4 года назад +4

      I was thinking this video was short until I saw your comment and noticed it was actually seven minutes!

    • @noname-wg5me
      @noname-wg5me 4 года назад +1

      1200 hour to make each video, how it couldn’t good

    • @dealwithit4345
      @dealwithit4345 4 года назад +1

      24minute and 30 sec felt like 7 minutes

  • @blueflowers.
    @blueflowers. 2 года назад +1

    I love the animations and shapes of the different complement proteins, it really helps me visualize how complement cleaves with each other like little puzzle pieces

  • @izzyp1162
    @izzyp1162 2 года назад +1

    Thank you for adding more detailed information too, I can use this video for a quick review for my exam as you also added pictures of the activation pathways.

  • @toastbot9496
    @toastbot9496 4 года назад +780

    Kurzgesagt: The Complement System
    Me: Finally something that appreciates me

  • @petarz1535
    @petarz1535 4 года назад +493

    Kurzgezagt: "Thank you so much for making this possible."
    Me: No, thank my Complement system.

    • @teochifor2017
      @teochifor2017 4 года назад +15

      Kurzgesagt just used the Compliment system

    • @James-le8gd
      @James-le8gd 4 года назад +4

      why don't you compliment your complement system?

    • @petarz1535
      @petarz1535 4 года назад +5

      @@teochifor2017 It's super effective.

    • @legendarytat8278
      @legendarytat8278 4 года назад +2

      I complement you all

  • @karachimechanical5834
    @karachimechanical5834 2 года назад +4

    I'm a ninth grade student and this is the perfect explanation about the immune system and complementary proteins thank you so much you guys are amazing

  • @MelodicalJazzyphile723
    @MelodicalJazzyphile723 8 месяцев назад

    Love everything about this video 👌🏾 great job! I appreciate the time and effort that went into this.

  • @bantot1296
    @bantot1296 4 года назад +1847

    _"Many mindless things can do smart things together"_
    *_Apes Together Strong_*

  • @Sethical
    @Sethical 4 года назад +4193

    dam they finally dropped Immune System 2 😳 this is some heat 🔥🔥🔥

  • @mikhail9417
    @mikhail9417 2 года назад

    Thank you so much guys for your labor!

  • @deoxi3207
    @deoxi3207 2 года назад +2

    It's always nice seeing these videos, I feel like I get smarter everyday even tho I may forget them in about five minutes.

  • @fluffbrain9832
    @fluffbrain9832 4 года назад +3133

    I'd rather have a compliment system, where all my cells say nice things to me

  • @Flamourist
    @Flamourist 4 года назад +562

    Kurzsegesat - this is an example of how many mindless things can together do something smart.
    Next Sentence: This video was sponsored by you the average viewer.
    Nice lowkey burn.

    • @JohnDoe-iw1mz
      @JohnDoe-iw1mz 4 года назад +21

      Damm..... that's deep

    • @ddoober
      @ddoober 4 года назад +14

      Heh heh this comment is great!

    • @PlaXer
      @PlaXer 4 года назад +4

      lmao

    • @JC-dq6us
      @JC-dq6us 4 года назад +4

      Next: many smart things get together to do something stupid.

    • @prismalglue
      @prismalglue 4 года назад

      i think it also kinda says humans were able to evolve from primitive animals into space faring civilization by co-operating with each other and thats the most importing thing to go forward. :-)

  • @peterh5165
    @peterh5165 2 года назад

    Good video! Thanks for putting this out to the general public.

  • @056vatsalapandey3
    @056vatsalapandey3 2 года назад

    you guys are the best, this is actually social work you doing here

  • @jameswong3318
    @jameswong3318 4 года назад +374

    "Complex and elegant dance"
    *Proteins float around aimlessly and bump into each other*

  • @lilacspring2556
    @lilacspring2556 4 года назад +845

    Now I'm a biochemist, and I have to say I'm very impressed with how you've simplified it for public consumption without changing anything

    • @papaoso8340
      @papaoso8340 4 года назад +24

      Yeah this Chanel is gold

    • @joost2260
      @joost2260 4 года назад +10

      @@papaoso8340 channel*

    • @normalguy5208
      @normalguy5208 4 года назад +1

      This is science

    • @Rb-hm5ml
      @Rb-hm5ml 4 года назад +1

      They are soooo good !

    • @papaoso8340
      @papaoso8340 4 года назад +5

      Joost
      Channnel?

  • @overdrivegaming3713
    @overdrivegaming3713 Год назад +2

    the fact that this all happens mostly randomly is insane

  • @roshinikanaparthi5618
    @roshinikanaparthi5618 Год назад

    OMG!!! I was trying to understand the complement system for the past 2 days.
    Seriously, what a splendid demonstration!!!!💯
    Thank u so much man❤️❤️

  • @axelbryden26
    @axelbryden26 4 года назад +1645

    "many mindless things can do smart things together"
    apes together strong

  • @thatguy.9886
    @thatguy.9886 4 года назад +489

    "A beautiful example of how many mindless things can do smart things."
    "This video was sponsored by you!"
    Wh- _HEY!_

    • @legendarytat8278
      @legendarytat8278 4 года назад +43

      Oh. You sneaky Kurzgesagt.

    • @MarcusBoyDS
      @MarcusBoyDS 4 года назад +10

      these guys are nuts

    • @Haloguy7
      @Haloguy7 4 года назад +13

      Son of a b-

    • @GoTeamScotch
      @GoTeamScotch 4 года назад +19

      Most elegant way to throw shade I've ever seen

    • @MayZen141
      @MayZen141 4 года назад +12

      Sarcasm level - GOD, kurzgesagt nailed it.👌👌👌

  • @ep8546
    @ep8546 2 года назад +1

    no but I need this to become a full length feature film because I am so invested 😻

  • @jedzliddington4401
    @jedzliddington4401 2 года назад

    Thanks for taking the time to make this video.

  • @arbitrarystuff1229
    @arbitrarystuff1229 4 года назад +1909

    You're Beautiful
    No you're more attractive
    You're such a wonderful cell
    I just love your protein shapes
    The compliment system

  • @poisonsoda8718
    @poisonsoda8718 4 года назад +330

    Every time you feel alone, think that there are billions of cells that are willing to give their lives for you

    • @spicketspaghet7773
      @spicketspaghet7773 4 года назад +14

      in reality, it's more akin to you sacrificing yourself to maintain yourself.

    • @Russ96
      @Russ96 4 года назад +3

      @Adromedox How selfish! 😄

    • @mohamedmoh5684
      @mohamedmoh5684 4 года назад

      @Adromedox who is you? !

    • @VanRukh
      @VanRukh 4 года назад +2

      Your cells are little tiny you's that are doing their absolute best to live and never giving up.
      GANBATTE!!

    • @tsubasawokudasai3473
      @tsubasawokudasai3473 4 года назад +2

      Cells at Work.

  • @kartavyapatel9222
    @kartavyapatel9222 Год назад

    Thank you for coming in my life , when I was in 11 th standard I took science and had lost interest in it , but you helped me get my interest back . I hope you people keep doing this good work

  • @tyvernoverlord5363
    @tyvernoverlord5363 Год назад +10

    Very interesting that the cells in our body have a biological IFF like we do in the modern battlefield for just about almost every combat capable ship, plane, and vehicle.

  • @augustmoso
    @augustmoso 4 года назад +2317

    I think this could actually be a fun videogame. Some players are bacteria/viruses and some are immune system parts. They both have to addapt to counter eachother, and some players can do like combos together to build stronger units, and... yeah that would be cool.

    • @vicentehodecastromenano2253
      @vicentehodecastromenano2253 4 года назад +102

      That would be a cool game

    • @legendarytat8278
      @legendarytat8278 4 года назад +262

      There's a game like that. It's called “Life”

    • @diollerena6497
      @diollerena6497 4 года назад +37

      August Solheim they made a movie about it called osmosis Jones haha

    • @ipwnalittle07
      @ipwnalittle07 4 года назад +51

      You basically described StarCraft, just with a immunology twist.

    • @eltriplej6944
      @eltriplej6944 4 года назад +11

      Yeah, pretty much rts games in a nutshell.

  • @noob19087
    @noob19087 4 года назад +774

    Someone should make an RTS game where you play as an immune system. That would be really cool.

    • @saifullahhabid1133
      @saifullahhabid1133 4 года назад +31

      Well, there is a game where a person plays as a viruse

    • @patrickberbon3135
      @patrickberbon3135 4 года назад +4

      dang ur right

    • @Mexicunny
      @Mexicunny 4 года назад +37

      Ok hear me out. It's a battlle royale. 1000000000000000000 players on each server. The goal is to either attack the cells or defend them 10000000000 players will be on the defensive side and the others will be bacteria. Who ever takes over the 1 cm of human body wins

    • @o76923
      @o76923 4 года назад +38

      An RTS where you have no direct control over any units and each unit's chance of performing an interaction is probabilistic instead of of deterministic would definitely be interesting.

    • @zandromex8985
      @zandromex8985 4 года назад +3

      @@Mexicunny Then it's not a battle royale...

  • @KYUBIMATIAS
    @KYUBIMATIAS Месяц назад

    Years later I come back to this video to help me relearn and appreciate complement. Thank you, Kurzgesagt, for animating this and making it digestible and fun. I still have the little cardboard complement system cards, too.

  • @KenanliaH
    @KenanliaH 2 года назад +1

    thank you! this video was very useful for my immune system assignment.

  • @beeptherobot9730
    @beeptherobot9730 4 года назад +987

    Kurtgesagt: Thank You for supporting us we love it!
    *Me sweating because I did nothing for them at all*

    • @thomascook3336
      @thomascook3336 4 года назад +40

      Share the video with others to increase their knowledge and potientally attract more supporters.

    • @ovencake523
      @ovencake523 4 года назад +32

      The other 14,999 ppl can support with donations and crap. But I'm just waiting on my kurtgesagt bird plushie!
      Actually, just by watching them, your supporting them in a minor way through ad revenue.

    • @vaylinne6093
      @vaylinne6093 4 года назад +9

      @BEEP The Robot You watching this video supports them :D It increases a relevance/popularity value stored for every RUclips video, which places the recommendation for this video higher in the list. Also they earn money if you watch the ads.

    • @Ze_eT
      @Ze_eT 4 года назад +4

      If you saw a single ad on a Kurzgesagt video, you supported them.
      Unless you got Adblocker.
      *We don't accept your kind here*

    • @theparrot7473
      @theparrot7473 4 года назад +1

      Well, watching their videos is supporting them

  • @dominatorandwhocaresanyway9617
    @dominatorandwhocaresanyway9617 4 года назад +437

    *I just realised that my body is Smarter that me.*
    Thats a weird thing to say

    • @hubi0079
      @hubi0079 4 года назад +10

      Welcome to kurzgesagt.
      Buy them posters.

    • @VikingMuayThai
      @VikingMuayThai 4 года назад +7

      You just understood your own soul bro O-O

    • @gutenman7112
      @gutenman7112 4 года назад +1

      I don't know which was responsible for that typo , your fingers or you ?

    • @xavierzabie8184
      @xavierzabie8184 4 года назад +3

      Always has been, always will be. Isn't it wonderful?

    • @ncedwards1234
      @ncedwards1234 4 года назад +1

      @@VikingMuayThai
      Nah, this is biology not supernatural stuff with no observations.

  • @corsairfilip
    @corsairfilip 2 года назад

    Hello, awesome video ! Just continue guys. Never see so compile it together as you describe it.