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@@Alilamedicalmedia Which type is involved in irritable bowel syndrome? Are gut allergy and leaky gut real and what type of hypersensitivity is involved?
Wow! This is the perfect explanation, very clear and summarizes the most important parts of each type. Taught me what I tried to learn for an hour and a half in 5 minutes.
This is almost impossible to study for a suppressant or a cure cause it's so rare to occur in ppl an it's even more rare for animals. Cause if you could come up with a suppressant or a cure you'd make big fuckin bucks mannee
HT - abnormal immune system reactions against specific antigens. involves excessive immune reactions to harmless antigens (allergens) and autoimmune reactions - immune responses against self-antigens. - reactions can vary from minor rashes to serious anaphylactic shocks Cause - self reactivity - during lymphocyte development - the B and T cells undergo various pathways that ensure that they do not react to self-antigens, and self reactive lymphocytes are eradicated. However sometimes some self reactive lymphocytes remain. and upon activation, they could mount an attack directed to the persons tissues. HT reactions only take place when the person has previously been exposed to the antigen, during which the body has created antibodies against the antigen or activated lymphocytes. HT divided into 4 types - have their own defining mechanism of action (most allergies are type 1) 1) first exposure to antigen -> IgE production by B cells -> attach to receptors (via Fc region) on the surface of mast cells. (the rest on my notes) chemicals released by histamine -> result in difficulty breathing due to bronchoconstriction. re-exposure -> reactions to antigen present immediately -> reactions can be mild e.g. severe e.g. anaphylactic shock - life threatening -> narrowing of airways and lowered blood pressure (epipen needed) 2) (IgG/IgM mediated) previously formed IgG or IgM (prod after first exposure)- bind to antigens on cell surface -> this antibody binding act as markers for the cells to be destroyed via complement or phagocytosis (called ADCC) - it is a cause of a lot of autoimmune diseases for example hemolytic disease of new born: D-antigens on the surface of fetal erythrocytes are bound by maternal IgG/IgM -> these red blood cells are destroyed. 3) IgG/IgM mediated - bind to soluble antigens -> forming antibody-antigen immune complexes -> complement system is activated -> inflammation -> tissue damage e.g. serum sickness - presence of a lot of antigens in the blood -> antibodies bind to antigens - form immune complexes -> deposition into the blood vessels. -> inflammation of blood vessels. 4) T cell mediated - previously sensitised T cells are re-exposed to the exact antigen. T helper cells release inflammatory cytokines whereas // cytotoxic t cells - release perforin and granzymes -> apoptosis e.g. T4 are basis for skin contact allergic reactions such as contact dermatitis -> skin tests like those for tuberculosis
Very useful and comprehensive video but I wish every single examples of the types of hypersensitivities are shown in this video. I liked it, waiting more videos like this
I have a question?? When the macrophages present the allergens which are non self antigens don't they engulf them to certain small antigen peptides that are displayed on their surface? How do they further (the allergens) go on to react on the mast cells if they are already processed.
I don't understand, it says on Google hypersensitive also means the sensitivity of skin aka what I have where I absolutely cannot stand the feel of dry stuff
Hi im a 24yrs old female ...... before thisyear i exprienced no allergy to paracetamol , flueout , neorgesic and i have used all of them !! but this year i exprienced allergy to flueout , neorgesic , and doliprane 1000mg ( hives and severe body neck face itching, but for the doliprane 1000mg was very severe itching that i couldnt stand and got hydrocortizion and desloratadine to supress it ... i was never like that before before this year sometimes ive taken 2 (1000mg) together but no problem happened i dont know whats the problem with me ...
there is likely hood of you having Rh imcompability in your future pregnancy if your last fetal loss was due to systemic hypersensitivity. make sure you receive a dose of anti D as early as possible on your next pregnancy
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Which type is involved in irritable bowel syndrome?
Are gut allergy and leaky gut real and what type of hypersensitivity is involved?
i watched this video this morning and i felt like the queen of hypersensitivity when i was writting my inclass test about it
Queen 😂😂😂
Why queen nor king then?
It was more helpful than my professors 3-hour-long classes thank you
You're very welcome!
@@Alilamedicalmedia
Which type is involved in irritable bowel syndrome?
Are gut allergy and leaky gut real and what type of hypersensitivity is involved?
Type-lll@@adeyemibabatunde1814
sorry i dont know answers but IBS is not a hypersensitivity Gut allergy is deu to Tpye1 IGE
Wow! This is the perfect explanation, very clear and summarizes the most important parts of each type. Taught me what I tried to learn for an hour and a half in 5 minutes.
True
literally
This is almost impossible to study for a suppressant or a cure cause it's so rare to occur in ppl an it's even more rare for animals. Cause if you could come up with a suppressant or a cure you'd make big fuckin bucks mannee
As perfect as it can get. Great work!
HT - abnormal immune system reactions against specific antigens.
involves excessive immune reactions to harmless antigens (allergens) and autoimmune reactions - immune responses against self-antigens.
- reactions can vary from minor rashes to serious anaphylactic shocks
Cause
- self reactivity - during lymphocyte development - the B and T cells undergo various pathways that ensure that they do not react to self-antigens, and self reactive lymphocytes are eradicated. However sometimes some self reactive lymphocytes remain. and upon activation, they could mount an attack directed to the persons tissues.
HT reactions only take place when the person has previously been exposed to the antigen, during which the body has created antibodies against the antigen or activated lymphocytes.
HT divided into 4 types - have their own defining mechanism of action
(most allergies are type 1)
1) first exposure to antigen -> IgE production by B cells -> attach to receptors (via Fc region) on the surface of mast cells. (the rest on my notes) chemicals released by histamine -> result in difficulty breathing due to bronchoconstriction.
re-exposure -> reactions to antigen present immediately -> reactions can be mild e.g. severe e.g. anaphylactic shock - life threatening -> narrowing of airways and lowered blood pressure (epipen needed)
2) (IgG/IgM mediated) previously formed IgG or IgM (prod after first exposure)- bind to antigens on cell surface -> this antibody binding act as markers for the cells to be destroyed via complement or phagocytosis (called ADCC)
- it is a cause of a lot of autoimmune diseases for example hemolytic disease of new born: D-antigens on the surface of fetal erythrocytes are bound by maternal IgG/IgM -> these red blood cells are destroyed.
3) IgG/IgM mediated - bind to soluble antigens -> forming antibody-antigen immune complexes -> complement system is activated -> inflammation -> tissue damage
e.g. serum sickness - presence of a lot of antigens in the blood -> antibodies bind to antigens - form immune complexes -> deposition into the blood vessels. -> inflammation of blood vessels.
4) T cell mediated - previously sensitised T cells are re-exposed to the exact antigen. T helper cells release inflammatory cytokines whereas // cytotoxic t cells - release perforin and granzymes -> apoptosis
e.g. T4 are basis for skin contact allergic reactions such as contact dermatitis ->
skin tests like those for tuberculosis
Thx mate 🙏
thank u. great simple summary
Great summary
Simply amazing! I always come to Alila for a brief, well explained straightforward overview of any topic before reading it.
Perfect! Clean! Excellent! Simple explanation.. thank you so much 😄❤
Thank you for this video now I understand inflammatory, auntoimmune and allergic disorders a lot more
This was such a helpful recap! THANK YOU
Very useful and comprehensive video but I wish every single examples of the types of hypersensitivities are shown in this video. I liked it, waiting more videos like this
As usual short and brief. thank you so much
Great video that covered all aspects so easily and concisely
superb...its so helpful in making difference of these four only in few minutes
Happy to help
Short and sweetly explained 😍
Feels very basic but still hard to differentiate! Wish it was more detailed or stated differences to distinguish between them in practice!
its made me crazy🤩really amazing explanation. go ahead👏
amazing! precise and great!!
God bless you
Amazing video! Thank you!
Very clear explanation 🎉
much better than my teachers
Precise and educative
amazing video! everything is explained right! thnak you!
Alila is the best
Thanks a lot. Perfect explanation.
This was so helpful dear🥺
Glad you think so!
very well explained, thank you so much!
Perfect amazing flawless
This explained to me very well. ❤
I have a question??
When the macrophages present the allergens which are non self antigens don't they engulf them to certain small antigen peptides that are displayed on their surface?
How do they further (the allergens) go on to react on the mast cells if they are already processed.
Clear and concise
thnks for Alila medical media i hope to get more video like this
Very well explained 👏
thanks for your efforts .this video and all of videos on this chanel are so helpful.
please do a video on birth asphyxia.
thanks
Thank youu❤❤❤
Tq so much very crystal clear explanation
Perfect explanation
Thank You ❤
Thank you for the video!
Are antibodies able to bind to everything it chooses including cell receptors, antigens, etc.?
great and nice lecture very helful
Kindly do a full explanation of asphyxia neonaturum please
automimmune diseases should be listed as type 3 too. This includes RA and SLE
well explained. but type 3 hypersensitivity is mediated by IgA and IgM, NOT IgG/IgM.
Hmm, look again! www.sciencedirect.com/topics/medicine-and-dentistry/type-iii-hypersensitivity
www.ncbi.nlm.nih.gov/books/NBK559122/
Thank you so much
GREAT VIDEO
That was helpful, thanks
Thank You.🙏🏻
Thanks a lot
I don't understand, it says on Google hypersensitive also means the sensitivity of skin aka what I have where I absolutely cannot stand the feel of dry stuff
Thank you
Thank u so much ..😭😭😭
Hi im a 24yrs old female ...... before thisyear i exprienced no allergy to paracetamol , flueout , neorgesic and i have used all of them !! but this year i exprienced allergy to flueout , neorgesic , and doliprane 1000mg ( hives and severe body neck face itching, but for the doliprane 1000mg was very severe itching that i couldnt stand and got hydrocortizion and desloratadine to supress it ... i was never like that before before this year sometimes ive taken 2 (1000mg) together but no problem happened i dont know whats the problem with me ...
Go to hospital
See a doctor
It's so helpful 👍🏼
Thank u soo much
Very nice 👌
Is this imminologic reactions?
Perfect ❤
Please try to reduce the opacity of thr water mark in the video... @copyright thing
Nice video ❤️
Which type is involved in irritable bowel syndrome?
Are gut allergy and leaky gut real and what type of hypersensitivity is involved?
Type 1 hypersensitivity I guess
Good vdo
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Nadia are you aware Che killed many innocents? And participated in the creation of forced labor "concentration camps" in Cuba?
Love this way 😍 thank you bae❤️
Easified 🙌🏻
Need videos of diabetes mellitus
Look for it in our channel!
Water mark is disturbing to read
please contineuse the video as soon as possible to upload
Ķkkk
Llllĺĺ
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Lhuóyy0kl
Awesome 🇺🇬
G thnks
you are the god
So can I have a normal pregnancy with type 2 ? I had a early miscarriage before I knew I was hypersensitive
there is likely hood of you having Rh imcompability in your future pregnancy if your last fetal loss was due to systemic hypersensitivity. make sure you receive a dose of anti D as early as possible on your next pregnancy
the watermark is too visible!!!
Nice
حي الله جماعة كلية بغداد
MCC mst
Since I started using Indian Echinacea Capsules, my skin looks clearer and more radiant.
WOOOOW :)
💙
OMG😳
Cancer empath
I didn't understand! Disliked. Sorry!
#official_tella
Thank you
thank you