It has been a MAJOR struggle to find accurate videos explaining this! You did a very nice job. You videos were enough for me to solidify my understand of this process! Thank you so very much!
Seriously, thank you so much for taking the time to make these fantastic videos. You are helping me tremendously on my endeavor pursuing the understanding of biochemistry. Keep up the great work, I hope somebody is paying you well
+tarac9 Hey! The link is in the description. You can donate on my website! Many thanks! But I think you already found it, so thank you !! Greatly appreciate it!
8:07 I believe you misspoke PC II when you meant to say PC I. Thank you so much for your great videos! Keep up the amazing and helpful content!! :) Your videos helped me through undergrad, and now I'm using them to review concepts in dental school! You're a life saver!
Sometimes you wonder why things have to be so complicated. Like, 4 complexes, really?? But thank you!! Super methodically detailed and clear! The best help I've found so far in my studies :)
Thank you very much for your time! Im not good with my English but your speaking is absolutely clear!! I checked a lot of videos but yours is detaled, accurate, and teaching - your explanation is fantastic!
Sometimes during the lecture, you say " Only protein complex 2, (while pointing on 1) and 3 and 4 act as proton pumps" around 8:09. Maybe you can put some signs there to correct it. Otherwise, great lecture!
10:00 Pretty sure it's called oxidative phosphorylation because the electron carriers lose electrons through sequence to generate ATP - not because complex IV uses oxygen.
LiNingAir Electron carriers in light reaction also lose electrons to pump protons and ultimately generate A.T.P. But instead of oxidative, it is called photophosphorylation. So he may be right about the oxygen thing.
Such a great lecture sir. I am preparing for my competitive exams with your lectures only. My request, can you pls upload lectures on BIOINFORMATICS topics?
Great presentation of the material! May I ask what technologies you are using to create this? I am an educator as well and love how you are incorporating technology like this with the presentation of your material. Thanks for any information you can provide.
oh my God l cant believe this topic is easy ,my lecturer just complicated it ,could you please come and teach in our university....lol.....l enjoyed the video
I really enjoyed the video doctor and studying the electron transport chain , it would be harder to understand without your perfect way , but pardon me Professor , I have a question , you said that CoQ is reduced to CoQH2 ,I don’t understand that point , complex I is supposed to be a proton pump , so where did it get the 2 H ions to be reduced , and of course it’s not going to be in it’s reduced form forever ,so how the CoQ will get rid of the 2H ions ?,
Like so many profesional science lecturers, you have someone who understands the subject really well, puting it out to people who don't, like trying to get them to drink from a firehose! Suggestion. Slow the H down!! FYI, I used to teach.
Hi Can I ask how many ATP molecules are produced in every ETC complex? It was actually raised by our professor, according to him, every complex in the electron transport chain produces a particular amount of ATP.. He wants us to identify the ATP molecules produced in: Complex I Complex II Complex III Complex IV. Thank you so much for those who can help☺️
At complex 1,ATP is produced Complex 2 ,1 ATP is produced At complex 3 ,1ATP is produced And no ATP is produced in complex 4 because here water is produced
Hey maaaaan, I get the first .5 q cycle and i get the second .5 q cycle , but how is the Ubiquinol regenerated within complex three after its release in the second half of the cycle ??..Because It goes into the inter membrane space as a fully reduced molecule . If you take another spin through the q cycle it will be lacking the ubiquinone , no?
Can you explain to me how 4 H+ (protons) are pumped out of NADH dehydrogenase (complex 1) PER NADH MOLECULE? Im confused because NADH --> NAD+ + H+ + 2e- Where am I going wrong? This is driving me nuts!
But your lecture is silent on what is the form of energy relesead during electron movement through complexes. And how is it responsible for the movement of proton from inner membrane to outer membrane????
Shafiul Alam Plus if you look at the structure, its not a transmembrane protein. It simply doesn’t have access to the other side of the membrane, thus not being able to pump the protons.
FAD is part of the complex; that is, it is attached to it and merely acts as a conduit for electron flow. During the Krebs cycle, FADH2 is formed, yes. But when it is formed, it is quickly converted back to FAD, releasing the H ions along with the electrons. These electrons move through Fe-S clusters and ultimately onto the electron carrier in the membrane.
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It has been a MAJOR struggle to find accurate videos explaining this! You did a very nice job. You videos were enough for me to solidify my understand of this process! Thank you so very much!
I honestly cant thank you enough for all your videos, you've made my life as a pre-med and soon to take the mcat much more bearable haha
You are better than my professor
Seriously, thank you so much for taking the time to make these fantastic videos. You are helping me tremendously on my endeavor pursuing the understanding of biochemistry. Keep up the great work, I hope somebody is paying you well
No one does it better. AK youre the best.
Thank you so much! These videos are a life-saver. Everyone should donate so we can keep this going!
+tarac9 Hey! The link is in the description. You can donate on my website! Many thanks! But I think you already found it, so thank you !! Greatly appreciate it!
Your videos helped me through pharmacy school. I’m most grateful
omg this video helps me to understand how ETC works, I've been watching so many videos and this one explains it clearly and detailed. Thank youu!!!
These lectures are the best I have ever had
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this is amazing! oxidative phosphorylation in a nutshell. this is for sure has been super helpful thank you for the effort put into this!!!
I passed my first biochemistry colloquium because of your lectures !!! Will donate
8:07 I believe you misspoke PC II when you meant to say PC I. Thank you so much for your great videos! Keep up the amazing and helpful content!! :) Your videos helped me through undergrad, and now I'm using them to review concepts in dental school! You're a life saver!
I figure since we all caught it and new exactly what he meant to say, it isn't so important to fix it.
@@ElanaSl This is true, just wanted to leave it here for anyone who might actually be confused. :)
Thank you. You have no idea how much you save me daily.
Sometimes you wonder why things have to be so complicated. Like, 4 complexes, really?? But thank you!! Super methodically detailed and clear! The best help I've found so far in my studies :)
saddlepotato159 it's not abig deal
I love your lectures!!! so helpful for biochemistry!
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Cygne Gris you're welcome! Thats awesome to hear! :)
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Thank you very much for your time! Im not good with my English but your speaking is absolutely clear!! I checked a lot of videos but yours is detaled, accurate, and teaching - your explanation is fantastic!
this guy seriously needs to be honoured with some sort of price because he's second to none in what he does.
Sometimes during the lecture, you say " Only protein complex 2, (while pointing on 1) and 3 and 4 act as proton pumps" around 8:09. Maybe you can put some signs there to correct it. Otherwise, great lecture!
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10:00 Pretty sure it's called oxidative phosphorylation because the electron carriers lose electrons through sequence to generate ATP - not because complex IV uses oxygen.
LiNingAir Electron carriers in light reaction also lose electrons to pump protons and ultimately generate A.T.P. But instead of oxidative, it is called photophosphorylation. So he may be right about the oxygen thing.
Such a great lecture sir. I am preparing for my competitive exams with your lectures only.
My request, can you pls upload lectures on BIOINFORMATICS topics?
U r just amazing in ur lectures
I'll recommend you forever!
this guy is a legend
You're a legend.
Great presentation of the material! May I ask what technologies you are using to create this? I am an educator as well and love how you are incorporating technology like this with the presentation of your material. Thanks for any information you can provide.
Thanking you is not enough 😍😍
How can we donate ?
Great as always. Wish I could donate more!
Thankyou so much
This is excellent
so simplified, thank you, sir.
oh my God l cant believe this topic is easy ,my lecturer just complicated it ,could you please come and teach in our university....lol.....l enjoyed the video
Thank you so much! :)) This helped me a lot
Amazing content!
I really enjoyed the video doctor and studying the electron transport chain , it would be harder to understand without your perfect way , but pardon me Professor , I have a question , you said that CoQ is reduced to CoQH2 ,I don’t understand that point , complex I is supposed to be a proton pump , so where did it get the 2 H ions to be reduced , and of course it’s not going to be in it’s reduced form forever ,so how the CoQ will get rid of the 2H ions ?,
Thnx for the superb lecture
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read the description
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Like so many profesional science lecturers, you have someone who understands the subject really well, puting it out to people who don't, like trying to get them to drink from a firehose! Suggestion. Slow the H down!! FYI, I used to teach.
Does superposition play any role in this process?
How is complex II called succinate reductase?
Are these complexes also known as integral proteins?
Great you!😊
are the complex 3 and 4 names interchangeable? my textbook has complex 3 as complex 4 and vice versa
Hi
Can I ask how many ATP molecules are produced in every ETC complex?
It was actually raised by our professor, according to him, every complex in the electron transport chain produces a particular amount of ATP..
He wants us to identify the ATP molecules produced in:
Complex I
Complex II
Complex III
Complex IV.
Thank you so much for those who can help☺️
At complex 1,ATP is produced
Complex 2 ,1 ATP is produced
At complex 3 ,1ATP is produced
And no ATP is produced in complex 4 because here water is produced
Hey maaaaan, I get the first .5 q cycle and i get the second .5 q cycle , but how is the Ubiquinol regenerated within complex three after its release in the second half of the cycle ??..Because It goes into the inter membrane space as a fully reduced molecule .
If you take another spin through the q cycle it will be lacking the ubiquinone , no?
Can you explain to me how 4 H+ (protons) are pumped out of NADH dehydrogenase (complex 1) PER NADH MOLECULE? Im confused because NADH --> NAD+ + H+ + 2e- Where am I going wrong? This is driving me nuts!
But your lecture is silent on what is the form of energy relesead during electron movement through complexes. And how is it responsible for the movement of proton from inner membrane to outer membrane????
hello. please what is the difference between electron transport chain in eukaryotic and prokaryotic cells.
Why etc should happen in stepwise manner .. I mean why complexes are...??? please ans
Thank you so much
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No explanation on why protein complex 2 can't pump protons. would be jubilant to get the answer
because it's not a proton pump? It's just an enzyme
Shafiul Alam Plus if you look at the structure, its not a transmembrane protein. It simply doesn’t have access to the other side of the membrane, thus not being able to pump the protons.
I love you so much
Great
Thanx
I thought the substrate for complex II is FAD, and the product is FADH2.
Confused by this too.
FAD is part of the complex; that is, it is attached to it and merely acts as a conduit for electron flow. During the Krebs cycle, FADH2 is formed, yes. But when it is formed, it is quickly converted back to FAD, releasing the H ions along with the electrons. These electrons move through Fe-S clusters and ultimately onto the electron carrier in the membrane.
Why am I paying for a university when I can learn much easier with AK lectures??
agent475816
i study without payment !
on point!!!
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