Yes, H3K27Acetylation will prevent PRC2 to deposit H3K27 methylation by direct competition and so H3K27Ac blocks silencing. Furthermore, H3K36 di- or trimethylation inhibits PRC2. see article DOI: 10.7554/eLife.61964 for an explanation of the mechanism.
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Thank you
is there a particular histone acetylation mark that affects PRC repression?
Yes, H3K27Acetylation will prevent PRC2 to deposit H3K27 methylation by direct competition and so H3K27Ac blocks silencing. Furthermore, H3K36 di- or trimethylation inhibits PRC2. see article DOI: 10.7554/eLife.61964 for an explanation of the mechanism.