What is Epigenetics? - with Nessa Carey
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- Опубликовано: 8 июн 2024
- Why your DNA is not your destiny. Molecular biologist Nessa Carey presents an introduction to epigenetics and explains how it shapes life.
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Nessa's book "The Epigenetics Revolution" is available for purchase now - geni.us/dOYAo
DNA is a vitally important starting point for life, but it's how it's used by cells and organisms that is really important. Epigenetics is a rapidly moving field that has transformed our understanding of how one set of genes can create the masterpiece that is each of us. It's also leading scientists into unexpected and exciting areas such as new ways to treat disease, understand drug addiction or unravel the lifelong consequences of early childhood trauma.
Nessa Carey is a geneticist and author of The Epigenetics Revolution. She has a degree in Immunology, PhD in Virology, was a post-doctoral researcher in Human Genetics, and a senior lecturer at Imperial College London in Molecular Biology. She's also spent 10 years in the biotechnology industry and now works in the pharmaceutical sector.
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She is an amazing educator. I am grateful to be able to access high quality lecture like this for free.
Imagine the world we'd craft for ourselves if all science was communicated so brilliantly and unpretentiously. Bravo.
Daniel Holley agreed
Daniel Holley 🍷. Drink to that.
Imagine the world ww'd craft for ourselves, if we just understood that our physical reality is a collective subjection/egregore structure
The problem is that not enough people are hearing it. The communicator is not the problem
I'm here after reading her book "The Epigenetics Revolution" to learn about possible updates in the field since it came out a few years ago. I would highly suggest the book to anyone as I had no background knowledge other than high school Biology and yet every chapter would blow me away.
This has to be one of the most interesting presentations I've seen in a while. Absolutely fascinating.
The most boring presentation. Boring verbal diarrhea and the poor woman is totally confused as to the meaning of Epigenetic. What saves her is the cute accent. She is trully the product of Rockefeller education system. Sad.
@@gracegwozdz8185. Well that’s a rather pretentious comment, given that she is an expert in epigenetics. Perhaps you would care to enlighten us with your wisdom on where she went wrong?
@@Pseudify david it seems worthless showing any sort of interest in these comments since it only demonstrates her mindset..or rather choice of one.
The 8 proteins are histones and form a protein complex known as a histone octamer, which is spool shaped (marshmallows were used in the demonstration). The 8 proteins in the histone octamer are actually 2 copies of 4 proteins, H2A, H2B, H3 and H4. DNA wraps around the histone octamer known as a nucleosome and they form chains like beads on a string making up chromatin. A nucleosome can be defined as a small length of DNA wrapped around eight histone proteins. The key difference between chromatin and nucleosome is that chromatin is a whole structure of complex DNA and proteins while nucleosome is a basic unit of chromatin. The beads on a string make up something called euchromatin or open chromatin that is enriched in genes and active under transcription (transfer of genetic instructions) which is why it is so important in epigenetics and changes in the phenotype (physical traits- e.g. appearance).
I absolutely have to watch this again and again. She has few equals in terms of clarity and lucidity. I am going to forward this to my entire family. One of the most interesting topics explained by one of the best presenters.
Amazing lecture! She takes complicated information and breaks it down into interesting info using jokes, history, stories, movies and more! Brilliant!
We really need epigenetics to advance as a civilization, some might even say it's... nessacarey
Yes - but we need the right stimulus; and that can come only from the WORD of GOD, found in the Bible. We could easily deteriorate into barbarism, especially if we start copying animals, instead of reminding ourselves that we are made in the image of GOD.
Eyes Open!
Caleb Smit I see what you did there 😂😂😂👍
Amazing
Well done
Finally! we have an exciting, summation of information about this field! Thank you for posting. Best explanations, clear analogies and diagrams I've ever found .I've been interested in this field for many years, though no longer a formal student. This great video brings me up to date.
Wonderful talk! I can't get enough of these Royal Institution lectures.
This is absolutely incredible! I'm completely floored.
This was the the biggest eye opener for me in the past years. This knowledge opens so many doors.
You make it so easy to absorb! You're an amazing professor! Thank you!
I'm currently reading 'Junk DNA' and I can assure you that it is really informative and it doesn't bore you. As a first-year medical college student, it is really helpful to visualize the epigenetic differentiation. Examples she gives are hilarious.
God does not make junk. Scientists don't know it's purpose so it is automatically relegated to the junk heap.
Superb presentation skills! Just the right amount of humor, story telling and information transfer to resonate with almost everyone.
Absolutely brilliant presentation. I just wanted to learn a little for my pathophysiology class and left amazed!
Her book, The Epigenetics Revolution, is fantastic by the way.
fantastic delivery of a fantastically fascinating subject -- thoroughly enjoyable, especially being a twin myself.
What a great presentation. Loved it!
Outstanding presentation
Reading her book now after watching this a few months ago! Brilliant and exciting literature! Epigenetics is such a fascinating field! This is telling us how we can affect our future progeny!
Name of the book?
The Epigenetic Revolution by Nessa Carey@@Anonymous-zy3lh
Fascinating subject, i'd never heard of this subject before. Props to the lecturer for giving such an entertaining lecture on a complicated subject! I hope you have her back again.
What a BRILLIANT educated and informative video, love it!
Thank you for the very fascinating and lively lecture! I love it!
Outstanding presentation. Very clear. Congratulations!!!!
What an incredible communicator. Science needs many more with her skill.
So well done. Answered questions I didn't know I had.
Such an amazing talk ma'am..really really loved it to the core...
I would very much like to hear professor Carey's view on the mRNA vaccines and their potential influence on the human epigenetics!
Extremely clarifying presentation, her book is also a gem of science communication...
SO intriguing! How the things, habits, nutrients we do now can genetically modify our future progeny!
She destroys it. Good talk. Her book gets a bit complicated at times but this is spot on.
Extraordinary lecture, thank you. blessings, Kimmy
Fascinating.
Interesting material and very well done presentation.
How fortunate that I in india can access this extraordinary lecture delivered so well and generously sprinkled with humor. Great contribution to science education. Have her books which are so precious for me
Fascinating, fascinating, fascinating. Absolutely fascinating.
I really enjoyed this talk thank you
Thank Nessa, it is my pleasure to attend your tutorial today at MCRS
Thank you for uploading. Very interesting☺️
First-rate presentation on this topic. Thanks very much.
What a brilliant lady!
Interesting topic, delightful presentation.
What a spectacular lecture!
thank you for sharing
Really good - packed with interesting insights and good for the RI to tackle what is admittedly a controversial topic.
Excellent; thanks for your great work.
A great way to transmit knowledge
Great talk
First time i am watching her. Today I purchased her book " The Epigenetics Revolution. Not my subject. But i have interest.
Happy to watch. Thank you Madam. Regards
An awesome presentation.
Its really a great lecture never had idea management student can enjoy science.
Great delivery
Great presentation. And she's just a natural. Very entertaining. 🙂
thank you so very much. This is wonderful. I am glad to say I was wrong.
all i can give to this lady is 🙇 Respect! amaizing
Its all actually very simple to understand when you grasp what is actually occurring in terms of epigentics and how we are products of evolution - genetics and events - what we do and what is done to us
Great lecture!
She's great ! ❤️
excellent video to describe epigentics, its a subject i wanted to write on next for my blog.
So much to love about this. Even all these years later rewatching it still give me all those uh-huh feelings.
Will be buying her book
Just wonderful! 🧬
well done and entertaining presentation on the topic of epigenetics
Well worth the listen! Thank you mame
Wow, really enjoyed this lecture. Any sociological/psychological applications or assumptions linked to these findings? ie, poverty, oppression, consistent trauma etc...
I'd love her as a professor for all my bio classes
Amazing teaching learning knowledge about the modification and genetic codes sequence of genome 🙏🙏👏👏❤️❤️💐💐
The DNA code starts from the same then the coding changes but the DNA coding is all the same in the start of the code. Example is like computer coding.
Code DNAMOMDAD then add on EYESLASHES or DNADADMOM Liver etc etc. It's so damn AMAZING
What a great woman !
Absolutely love her x
Brilliant talk, engaging presentation..... - i feel for the mice, though.....
Brilliant Thanks
Crocodiles and Dinosaurs share a common ancestor, crocs are not descended directly from dinosaurs.
Brilliant talk, especially your dna analogies
All I want to do right now is eat strawberry laces and jelly tots.....on a serious note, this lecture was FASCINATING - thank you Nessa for your fabulous energy teaching this
Oh no! Your exposure to the video (environmental factor) has changed your mental content, which could change your behaviour which could change your epigenetics, which could change the future of your offspring?
Good grief this rabbit hole goes deep...
THANK you now I kind of get it
This was so interesting . Thank you very much
Great video! I can imagine that practical living advice can come from epigenetics, like how i can change my own in a positive way. Any chance to get that?
Hmm, for example if you don't smoke, your epigenetics for requesting more nicotin don't get switched on and your kids probably won't smoke either. Does this answer your question?
Fantastic, Love the energy your brought to your book The Epigenetics Revolution"
I wonder if you can see the link between Epigenetics and Buddhist Karma.
(They are both very deep matters)
Any Buddhist's out there pls read this and think....
Thank you for great presentation! Ive been thinking about one question. In the "bullied" mouse experiment epigenetics were not transmitted but in cherry blossom smell, the fear was transmitted to offspting due to epigenetics. Is that a contradiction that in some cases environmental quality gets passed in others not?
so the dna is still the same, just the little "jelly" dots that attach to the dna that a person might develop while interacting with his environment? But what's the mechanism behind the epigenetic changes (my guess it's still the DNA that gives instructions to the protein to make the epigenetic changes)...I mean could epigenetic changes lead to the eventual creation of a new species? Thinking more ahead, how much can we augment our body through tweaking the expression of various genes, like would we be able to grow a new arm through epigenetics, or is that sort of mutation still dependent on the manipulation of DNA? You say that the little "jelly" dots, sorry I forget the exact term you used for those molecules, attach to the genes and affect their individual expression, but how many genes do we have, what are each gene's functionalities, how does each gene interact with each other, and what explains the difference between us and a chimp or a bird or something? God damn it get more research done lady!
My back is hurting from watching all these Royal Institute videos laying on my bed at 1AM in California, and I also don't have a car to go to work tomorrow morning, and I think it'd be really nice if DNA technology can allow me to grow a pair of wings! (though the image might be a bit grotesque) so I can fly around to work and buy groceries or something...
EXCELLENT
brilliant
This is EPIC!! Lamarck is partly vindicated, but that's the least of it. We are more "adjustable" than we realized before, and some of these adjustments can be passed on to the next generation. LOTS to think about, even for the ordinary person in the street who wants their offspring to be healthy and talented.
Would a babies/child’s dna receptors be affected/changed by a traumatic birth experience?
Ie would a more ‘relaxed’, non stressfull/traumatic birth experience have a better outcome for a child later in
Life?
One of the best speakers I've seen on this channel. We need more sweets-based analogies in scientific discourse.
Andri Eiríksson something with chocolate in it would be nice.
She is long-winded and boring.
There's one thing I am confused about. So if the histones are wrapped around our genes, and say you become a smoker (but no one in your family tree extending hundreds of years smoked) and the chemical tag is added to the histones to make that gene become 'expressed', does that mean that the 'smoker gene' is predetermined? In other words, will I have a 'smoking gene' by default that is turned off, but will only be turned on if I smoke?
If for whatever reason molecular biology doesn't work out for Nessa Carey, she can surely do well as a stand-up comedian! Very entertaining and enlightening talk!
Always love a new RI video, always get annoyed about the huge difference between the sound level of the title credit and the lecture itself.
We've actually fixed this! We hope. For the last month or so, we've been making sure that the volume of the ident is less than half of what it was before. This video is slightly older so will still try to blow your eardrums out, but hopefully you won't run into this with any of our newer stuff. Do let us know if it's still too loud though.
fantastic - thank you so much for posting
How do you determine if a characteristic is truly determined epigenetically or if there is some other factor, like the chemicals given off by gut bacteria, or some changes triggered by viruses, or some other mechanism I can't think of just now?
It would be interesting to know what foods could turn on or turn off gene expression in humans and the outcome of the change.
Showed this video to a friend. She responded, "it's true with exception to Mary, the mother of Jesus".
We need more real scientist dedicated to discover and instructs and inform us broadly . Thank Madam
Nithya
Intellectual, Kindle the mind to know more about epigenetics Thanks
Mary Poppins is awesome at science!!
Got her books
Are the 8 proteins in the nucleus of the same composition in everyone, or are they widely differing?
Does anyone know if algorithms were used to define theoretical epigenetic research concepts individually and where to find the results? Im into pattern recognition.
Awesome
Wow, she is brilliant!!
Out to pasture!