Was looking for a source that collects all this information and explains it in a easy to understand way. Better than hunting in multiple books and online and getting lost with memorizing!
on 14:14 i completely lost it. so many things that could be implied there. You are absolutely right! Scientists are mean by giving the same things a gazzilion different names. This is far from the only example where it happens.
Here for reference, instead of going back and forth to my iBooks and pausing. Thank you. Large B cell lymphoma. Large atypical cells positive for cd20, pax5, significant patchy staining for bcl-6. The large cells are negative for ae1/ae3 cd3,c5,cd10, and cyclin d1. Small background lymphocytes show populations that are both cd20 and pax5 positive as well as a population that is cd3 cd5positive. Positive staining for bcl6 may indicate lymphoma of center cell origin.
So what does this mean Absolute CD&+ Lymphocytes (H), CD16+CD56+ Lymphocytes (H), Absolute CD16+CD56+Lymphocytes (H), Absolute CD19+ Lymphocytes (H) My son is six and this is his blood work
If anyone here is studying this subject I would like to ask you some question. To produce antibodies, which cell is involved ? It a fault of the naive B cell ?
A naive B cell activated by an APC either macrophages and has undergone clonal expansion to class switch into the required antibody specific for the antigenic stimulation. So in essence the naive B Cell needs to be activated by presenting Ag to the T helper Cell by MHC class 2 and co stimulatory b7/CD28 interactions leading to clonal expansion and SHM of specific antibodies for the Antigen.
@@benjaminansah-agyei139 Thank you very much. I have a seronegative celiac disease which is now into a refractory celiac type 1/2. Unfortuantely I also have sublinical hypothyroidism with negative Tpo antibodies. I wanted to be tested for Iga or Igg deficiency but it seems that my values were fine. How can I be tested for a naive b cell defects?
Was looking for a source that collects all this information and explains it in a easy to understand way. Better than hunting in multiple books and online and getting lost with memorizing!
I've never seen a teacher explaining this. Life could be a lot easier if they all had that simple idea.
I work as an immunologist at JnJ and man this is crazy helpful. Always need a refresher.
Like all gems, these lectures are hidden. Salute to Maureen!
on 14:14 i completely lost it. so many things that could be implied there. You are absolutely right! Scientists are mean by giving the same things a gazzilion different names. This is far from the only example where it happens.
Thank you for your concise explanation. my question is, can cells be double positive for cd 4 or cd 8 without being positive for cd45
Here for reference, instead of going back and forth to my iBooks and pausing. Thank you.
Large B cell lymphoma. Large atypical cells positive for cd20, pax5, significant patchy staining for bcl-6. The large cells are negative for ae1/ae3 cd3,c5,cd10, and cyclin d1. Small background lymphocytes show populations that are both cd20 and pax5 positive as well as a population that is cd3 cd5positive. Positive staining for bcl6 may indicate lymphoma of center cell origin.
how comes this does not have more views! AWESOME VID. thx!
I actually didn't find any perfect explanation.. You really helped me a lot
Did you learn since what CD19 role is for? I have chronic reactivating EBV and my CD19 marker is high.
That's truly useful, Thanks a lot for presenting such a brilliant lesson.
Thank you so much doc.This will help me a lot with my steps exams, appreciations !
Outstanding presentation! Thank you 🙏
10:54 So what you're saying is pembrolizumab (PD-1 receptor antibody) is basically like a "T-cell red bull" that keeps them going for longer?
amazing explanation
Amazing
Hi Maureen what does a High CD4/CD8 Ratio Mean?
For a moment I was like why would anyone review CD marker pens. My bad. Thanks for the video.
You should get a Nobel!
that is not how it works..
Thank you very much! Very useful!
So what does this mean
Absolute CD&+ Lymphocytes (H),
CD16+CD56+ Lymphocytes (H),
Absolute CD16+CD56+Lymphocytes (H),
Absolute CD19+ Lymphocytes (H)
My son is six and this is his blood work
Following- did you get results?
I don't know what to say but you are an awesome memory cell
thank you so much for the review.
You're a godsend!!!
Superb 🎉
If anyone here is studying this subject I would like to ask you some question.
To produce antibodies, which cell is involved ? It a fault of the naive B cell ?
A naive B cell activated by an APC either macrophages and has undergone clonal expansion to class switch into the required antibody specific for the antigenic stimulation. So in essence the naive B Cell needs to be activated by presenting Ag to the T helper Cell by MHC class 2 and co stimulatory b7/CD28 interactions leading to clonal expansion and SHM of specific antibodies for the Antigen.
@@benjaminansah-agyei139 Thank you very much. I have a seronegative celiac disease which is now into a refractory celiac type 1/2.
Unfortuantely I also have sublinical hypothyroidism with negative Tpo antibodies.
I wanted to be tested for Iga or Igg deficiency but it seems that my values were fine.
How can I be tested for a naive b cell defects?
Omg this was soo helpful.. THanks a ton.. 😊
are also eosinophils induce in class switching from IgE to IgA with il 5 ?
Good video, I found it very useful!
Amazing, thank you so much!
You are just amazing thank u ❤
u r amazing u r grear
Thank you soooo much!
I love love love this
Nice 👍
Thank you
Sensational
Hero's work! :)
Thank youuuuuuu