I guess im randomly asking but does anyone know of a way to log back into an Instagram account..? I stupidly lost my login password. I would love any tips you can give me.
DUDE!!!!!! Holy shit, I've been battling to understand the crossing over and this video showed it in a way that gave me that EUREKA moment. Thanks a million!
Whilst the middle of the orange and blue strands have 'crossed over' it is non-crossover as the rest of the chromosome is the same as before. The orange DNA (depending on where it has come from - sister chromatid/homologous chromosome) should be pretty much identical to the corresponding blue DNA so it won't make too much of a difference that it is in a separate strand as it is only a small section of DNA, although mutations may arise,
waou !! ta vidéo est géniale, tu m'aide beaucoup merci merci !! :D (thanks a lot, I love you !! I have been spending hours to try to get this systema !! )
Where it says 'non-crossover products' surely the light blue strand would go back to its original position, as by moving to the orange strand surely that is a crossover product. I'm not sure any help would be great :)
Dangit, I wish you had animated the actual cutting and crossing instead of just showing the new products. I have trouble visualizing what is linking to what to get these new sequences. :(
Nice work but there are a few mistakes. 1st, there is no experimental evidence that Dmc1 and Rad51 bind on opposite sides of a break. 2nd, the free 3' ends after resection are invading the wrong strands. The yellow should pair with the dark blue and the orange with the light blue (assuming the top DNA strands are in the same 5'-3' orientation as the bottom ones). 3rd, after crossover, the top most strand has become inverted:it should finish with dark blue on left and yellow on right (at 1'10'')
Excellent video, thank you for your help. It would have been nice if the top strand was not reversed and the cross-over product didn't happen so quickly though, but anyways I get it now.
I don't understand why the first cleavage gives 'non-crossover' products as one of the strands in each chromosome is now made up of some DNA from the other??
This is not correct! Mre11 (part of the MRX complex) has 3' to 5' exonucleolytic activity while Exo1 does 5' to 3' resection. As a result, you get bidirectional resection resulting in 3' ssDNA tails. What you show here is MRX complex with 5' to 3' exonucleolytic activity.
Insane work. Thanks man. Your video is still helping people 13 years later!
I couldn't help but spit a lil freestyle while watching the video
Felix Page same here!
I guess im randomly asking but does anyone know of a way to log back into an Instagram account..?
I stupidly lost my login password. I would love any tips you can give me.
@Lian Benton instablaster ;)
Lmaoooooooooooooooooooooooooooooooooooo
@@lianbenton9174 this comment reminds me of times when the internet was a cooler place
How long I have been searching for such an animation! Really really well done!
Incredible video. Thanks for taking the time to illustrate this process in such an easy-to-understand way. Subscribed.
This video explained me what two professors and a textbook couldnt
Thank you!
1 hour lecture summarized in a minute :) thanks a lot
no joke. the most... .awesome vid ever. thank you so much.
DUDE!!!!!! Holy shit, I've been battling to understand the crossing over and this video showed it in a way that gave me that EUREKA moment. Thanks a million!
Thank you so much!
I'm 1st year in med studies and this was a big help :)
at 1:11 , the top strand should have the black end to the left and yellow end to the right.
Other than that, very useful video!
I think the crossover product is not correct! The top strand should be small velvet to the left and long yellow to the right! Or I didn't get it?!
Yep, you're absolutely right.
Yes you're right
Glad to know I'm not going crazy
thanks, I was about to cry
A vertical cut to holliday junction causes the rotation of DNA strands. The crossover product is correct.
This saved my life. Thank you so much!
Whilst the middle of the orange and blue strands have 'crossed over' it is non-crossover as the rest of the chromosome is the same as before. The orange DNA (depending on where it has come from - sister chromatid/homologous chromosome) should be pretty much identical to the corresponding blue DNA so it won't make too much of a difference that it is in a separate strand as it is only a small section of DNA, although mutations may arise,
i'm in medecine studies and it help me a lot !
thank you guy !
1:06 I can't understand how that cleave would result in the final model 1:10
This is so helpful! I actually understand it now, which is great lol (seriously, why are textbooks so confusing?).
I did suscribe for the beat. Simple, clear, and cool animated.
very helpful. exactly what i was looking for. thanks
short condense and clear
The top most strand cleaved should have had yellow short segment and long purple/blue segment and vice versa for the bottom most strand.
Thank you this was really helpful for visualization
waou !! ta vidéo est géniale, tu m'aide beaucoup merci merci !! :D (thanks a lot, I love you !! I have been spending hours to try to get this systema !! )
Where it says 'non-crossover products' surely the light blue strand would go back to its original position, as by moving to the orange strand surely that is a crossover product. I'm not sure any help would be great :)
thank god i found this video. i was stuck understanding it by A A' a a' .
Appreciate the effort....
Commenting for algorithm..
SUCH A BOMB VIDEO THANKS
* twerks instead of studying * good music out there and great work! thanks alot
crossover part is so confusing!
Bc it's wrong
simple and elegant... i like the MUSIC....
I love this music
Thanksssssss a lot
This is awesome
Ive been tryna understand this and i did finally
Thank you so much for making this video! It really helps with my revision :^)
really diggin this
very nice and useful
thank you
Wow! this video is Awesome!
Thanks so much for posting this!
great video and more clear to me
Dangit, I wish you had animated the actual cutting and crossing instead of just showing the new products. I have trouble visualizing what is linking to what to get these new sequences. :(
Same!
Thanks for that!
Very nice!
Is there something wrong? in 1:12, the deep blue fragment in the first row should be putted in the head of the first row
I love you for this 😭
Nice explanation. Got a final in 12 hours for genetics.
thank you for making this!
Best yet.
Helpful video.. 👌
Awesome video
im not gonna ask for the instrumental's name because you guys will just say darude-sandstorm
Darude-sandstorm
Did you find the song name by any chance?
@@kirpalpanacer2638 yes, it's Darude-Sandstorm
Darude-sandstorm
@@francescogallo4562 Aaah I get it. It's darude - sandstorm
i think the very top strand has just been placed the wrong way around, ie 3' is in 5' position and 5' in 3' position
merci elsa
Wow!! that was very helpful!! Thanks!! :)
thanks, great video :)
this is super cute and also helpful 😏
yr super cute, what is you phone #. can i take you to the ballet? chopin?
you are amazing
thanks
Lifesaver!
Nice work but there are a few mistakes. 1st, there is no experimental evidence that Dmc1 and Rad51 bind on opposite sides of a break. 2nd, the free 3' ends after resection are invading the wrong strands. The yellow should pair with the dark blue and the orange with the light blue (assuming the top DNA strands are in the same 5'-3' orientation as the bottom ones). 3rd, after crossover, the top most strand has become inverted:it should finish with dark blue on left and yellow on right (at 1'10'')
Which are the red enzymes in the end?
this is pretty dope
what a tune
Excellent video, thank you for your help. It would have been nice if the top strand was not reversed and the cross-over product didn't happen so quickly though, but anyways I get it now.
amazing :D thank you so much!
Nice way to make an animation. Great!!
best biology video i've seen in a very long time, thank you!
What is the mean BAM and MRX ??
AWESOME!
sick vid
thank you!
Pretty good until crossover resolution. You shouldn't get heteroduplex on the two ends of the top chromatid. Problem comes in between 1:07 and 1:08.
Perfetto! Got it
what's the name of this beat? who made it?
Forgot the Rad52 and Rad59 proteins that help. I like it though.
Very Cute!
Merciii
Thanks pal, unfortunately this never came up in my exam :(
Would God like his design better? Would he dwell there in with the changes? Is not the body Gods temple?
Thanks a lot ;)
Damn what is the track playing ?
song ?
Ruv proteins: Am I a Joke to you?
perfect
Looking for the author of this music, some chill beats. Please respond :-)
can someone ID the song pls
Your crossover products are inaccurate.
BAM!
Dope.
they really hold your hand through it. for the slow learners like us:)
goat
Cool
SIR ACTUALLY THIS IS NOT TWO HOLLIDAY JUNCTIONS MY PROFESSOR SAID IT IS ONLY ONE PLEASE CORRECT YOUR VIDEO
👏👏
hot beat
Good music
i love you
Song?
I think its bone thugs in harmony slowed and throwed
I don't understand why the first cleavage gives 'non-crossover' products as one of the strands in each chromosome is now made up of some DNA from the other??
thank you based god
This is not correct! Mre11 (part of the MRX complex) has 3' to 5' exonucleolytic activity while Exo1 does 5' to 3' resection. As a result, you get bidirectional resection resulting in 3' ssDNA tails. What you show here is MRX complex with 5' to 3' exonucleolytic activity.
Holy fuck....it is helpful
choon!!!
That's the szostak modell :((
Seek Christ Jesus YHVH God Almighty !
Touch my cheddar, feel my beretta...