you ate this up bad. this was super helpful. i know it is now over 10 years old, but thank you sm! i hope you are doing well and still providing incredible explanations.
Hi, I am a 3rd year biology student and I found your video amazing. Especially for the explanation of Holliday junctions which i previously did not understand. My prof explained it to us but definitely not in the same way as you. Thanks so much!
Great video, really informative! I was just wondering, at around 9.40 you speak about how the base pair mis-matches can be fixed in the newly formed hetero duplex, how does this happen and what allele for the genes will come about after the fix? Surely its not possible to have a gene that has a strand from each allele, or is it?
A question: during the explanation of the slide which start at 3:23, you say that the first case represents the segregation following Mendel's theory (I'm speaking about the nonrecombinant AB and ab). Although, the Mendel's law of independent assortment states that allele pairs separate independently during the formation of gametes. This means that traits are transmitted to offspring independently of one another. So, I think the first case presented in your video is actually an example of nonmendelian assortment, which is typical of linked genes. Am I right?
i am sorry but i am very sure that the recombination is induced by a DOUBLE strand break on one chromatid! after that endonucleases cut the open ends in different directions, one strand invades the other chromatid and forms a D-loop. after that there is a second end capture etc etc..
you ate this up bad. this was super helpful. i know it is now over 10 years old, but thank you sm! i hope you are doing well and still providing incredible explanations.
Hi, I am a 3rd year biology student and I found your video amazing. Especially for the explanation of Holliday junctions which i previously did not understand. My prof explained it to us but definitely not in the same way as you. Thanks so much!
Rec A binds a 3' overhang, not 5' overhang.
Oh my if I get asked about this in exam I'm screwed :D But it's a great video, thank you :)
Great video, really informative!
I was just wondering, at around 9.40 you speak about how the base pair mis-matches can be fixed in the newly formed hetero duplex, how does this happen and what allele for the genes will come about after the fix? Surely its not possible to have a gene that has a strand from each allele, or is it?
A question:
during the explanation of the slide which start at 3:23, you say that the first case represents the segregation following Mendel's theory (I'm speaking about the nonrecombinant AB and ab). Although, the Mendel's law of independent assortment states that allele pairs separate independently during the formation of gametes. This means that traits are transmitted to offspring independently of one another.
So, I think the first case presented in your video is actually an example of nonmendelian assortment, which is typical of linked genes. Am I right?
so thanks, i need more videos like this
Commenting so I can find this later.
+ElNick09 There's this thing called "Favorites"...
you sound like Caliiope
What happened to missmatched area
i am sorry but i am very sure that the recombination is induced by a DOUBLE strand break on one chromatid! after that endonucleases cut the open ends in different directions, one strand invades the other chromatid and forms a D-loop. after that there is a second end capture etc etc..
oh i am sorry, i commented before i reached the end of your video!
Thanks
thank
So the whole recombination process probably evolved from a simple dna repair protein mechanism?