Menopause/hormone therapy, Pt. 2: fact or fiction? (w/ Avrum Bluming, USC) -Get Real Health
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- Опубликовано: 17 фев 2021
- Dr. Chana Davis hosts Dr. Avrum Bluming to discuss menopausal hormone replacement therapy, with the goal of empowering women to make choices rooted in science.
Bluming explains the different estrogen replacement strategies, from bioidenticals, to Premarin, to patches, including what we know, and what we don't know, about these options. He also shares insights into the notorious Women's Health Initiative (WHI) study that sparked many common, yet unfounded, fears and explains why there is such a disconnect between the science and the headlines.
This episode is the second of a two part conversation. Check out part one for an overview of the risks and benefits of hormone replacement therapy.
Dr. Avrum Bluming is a hematologist, medical oncologist, professor, and cancer researcher. In addition to treating women with breast cancer for four decades, Bluming was a clinical professor of medicine at University of Southern California and a senior investigator for the US National Cancer Institute.
Together with Dr. Carol Tavris, Bluming literally wrote the book on post-menopausal estrogen therapies. Learn more about Bluming, Tavris and their book, Estrogen Matters, including links to the latest scientific studies at: estrogenmatters.com/
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Get Real Health provides science-based insights so that you can make smart, healthy choices. Dr. Chana Davis (PhD, Stanford genetics) interviews leading experts who share practical, science-based advice and bust common myths and misconceptions. Show topics span food (nutrition, toxicology, weight loss), exercise, infectious diseases (microbiome, COVID-19), public health (vaccines), and mental wellbeing.
Access more of Dr. Davis' work:
Website: fueledbyscience.com
Instagram: @fueledbyscience
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Twitter: @fueledbyscience 
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Menopause doesn’t just end. I’m 79 and still have menopause. It didn’t stop. I need HRT for life ❤ Estogen really matters!!
What an excellent interview. If like to see him talk with Dr Louise Newson here in the UK as she's the UK advocate and she's on you tube too fyi.
What I want to know is more about is the how and why we are living longer and what is a typical lifespan for humans. Because clearly living longer we live without our hormones which clearly isn't normal.
We are living longer because we aren't dying of contagious diseases as much now.
@@iss8504 that's true indeed nit I don't think that's the full story.
A health care system that saves lives - all kinds of therapies -blood thinners that stop blood clots. Clean water, better nutrition and vaccinations which do prevent diseases spreading. I lived in Brazil and Colombia where there was no clean tap water without fitting filters and having access to a supply. No Public Health Service. Think about it
Can’t believe he supports using Premarin. Needs to update his research.
I agree he needs to update his research and hopefully he has since this conversation posted 2 years ago. Prometrium, progesterone not Premarin is a better choice….perhaps he needs to watch Menopause Taylor on RUclips as well…..
Premarin is fine. The studies show that they might be especially beneficial for mental clarity.
The WHI study issues were with the progesterone used. A different one is now used.
Premarin has good study info. People dislike it because of the way it collected. That is separate from whether Premarin is dangerous.
It's common sense to know horse urine isn't good to take. Also, no horses are going to be abused for my bioidenticals.
@@iss8504 the WHI study used progestins not progesterone. You’re mistaken. And Premarin is not fine. It has 17 estrogens in it which are good for horses but not humans.
@@bluejean-1968 common sense isn’t very common, unfortunately.
I am sitting in a post Hysteropathy procedure feeling confused by a 3 month bleed which is likely caused by a Polyp which was removed.
I couldn’t get Micronised progesterone during the shortage and missed 2 weeks - I believe the missing of 2 weeks caused the bleed. The Doctor said reduce the oestrogen bit actually that is dangerous for me as I have osteopenia and a fracture in my neck and a middle age spread …heart disease ! I was told no by a haematologist in 2013 and he was wrong! I missed 9 years! Could avoided my teeth cracking and being told tough luck?! I m on HRT for life - I ll preserve my working years which is my aim!
Really interesting. Thanks for sharing
Thank goodness I listened to this ! And i m using my oestrogen from today at the dose that gives me a therapeutic effect - not the teaspoon effect. So pleased I can take my oestrogen !
My problem with Premarin is how it is made. I have a huge problem with it. If you don't know, look it up. It's not just about the mares but what they do with any male foals that result from the forced pregnancies. Female foals are kept to make more Premarin.
You shouldn't use the old synthetic PREMARIN! Absolutely right! Use modern HRT: bodyidentical Oestrogen in gel form ( it's made out of natural products like the Yam root)!!!! No suffering animals needed anymore!!!
Premarin 0.3 mg. It gave me my life back.❤
While the conversation is great, I need a doctor that will help me post breast cancer.
What dose is better if is not symptoms and you want for prevention
Thank you for including some talk about FSH levels in this talk but I wish you would have discussed what FSH level, or what range of FSH levels, were indicative to that there is enough circulating estradiol in the system.
Excellent! 57 need to take it !
Me too!
REALLY INTERESTING STUFF.
I used to take BHRT from a compounding Pharmacy, but when I take Prometrium compare to Compounded Prometrium - it is very different. The Prometrium comes in a 30 pack by drug company is much stronger like 30-40%. I still get some hormone from the Compounding Pharmacy, but I am much more aware now. If I can get the pharmacy brand, I rather get it from there, as the dose will be more accurate.
How do you know for sure it is more accurate?
@@panes840 The pharmacy only dispenses what is standardized and approved by our over seeing agencies By prescription.
I was so hopeful and excited that perhaps i could manage all these horrible debilitaying meno symptoms and I listened with excited until at the end you said to use NAMS as a guide. I had a 7mm stage 1 pea sized HR+ Invasive Ducta Carcinomal breast cancer that was successfully treated with lumpectomy and radiation. NAMS says absolutely No HRT of any kind after successful treatment. I am so depressed and dysfunctional I just want to die.
You could attempt a waiver. We should be allowed to assume risk for ourselves. Menopause symptoms are debilitating.
Suzette, the 2017 NAMS position statement on HRT reads like this:
*Systemic HT is not recommended for survivors of breast
cancer, although selected cases with compelling reasons may be discussed in conjunction with an oncologist after nonhormone options have been unsuccessful.
* For survivors of breast cancer with bothersome GSM symptoms, low-dose vaginal ET, with minimal systemic absorption, may be considered after a failed trial of non- hormone therapies and in consultation with an oncologist. There is a concern even with low-dose vaginal ET for women on AIs because of suppressed estradiol levels.
In Estrogen Matters, Chapter 6, he addresses HRT in Breast Ca survivors- I highly encourage you to read this and then have a conversation w/your oncologist. Don’t give up just yet ! Risk vs benefit has to be individualized ! ( He even mentions in the book that his own daughter decided on HRT, s/p Breast Ca )
Hope this helps! - from your friendly hospital pharmacist ;)
Dear fellow sufferer,
don't despair!!!!
Go over to the podcasts of Dr. Louise Newson - she is a British menopause specialist who suffered perinenopausal symptoms herself. She has all kinds of different podcasts: several also cover the topic of HRT and breast cancer. I love Dr Blooming dearly, he simply brilliant and I'm so thankful for his work, but he has to be conservative with his advice for age groups beyond 60 whereas Dr Newson can rely on her own experience with thousands of women.... Don't give up and if you feel suicidal: GET HRT no matter what age or type of cancer: even the rezidivism rates of BC are lower for women on HRTplus their overall survival rates!!!!
❤ to you...
.... please don't give up!!!!!!
I wonder if the study by WHI adjusted for dietary factors? Example- Vegans and non dairy consumers, vs. Standard American diet eaters of meat, dairy, eggs and processed foods?
... no but a majority was severely overweight!!! 🥸
They looked at SAD diet vs lowfat diet. Women with existing heart disease who went on lowfat diet fared WORSE than women who stayed on SAD diet. Only healthy women had reduced heart disease on the lowfat diet. If you consider that 93% of the adult population has one or more metabolic factors, it would seem that going low fat is a bad idea.
I wish I had known about fixing my hormones
My notes
18:30 dosage cycling
Bioidentical it’s not approved, oral is bad for your liver what is recommended?
0.5 transdermal estradiol patch is the lowest dose to protect for the 3 major diseases
@@summerrain1579 , what do you take for testosterone?
Watch Menopause Taylor on RUclips
@@emeritajimenez8521 I dont. My testosterone levels are fine.
I break off an estradiol at 0.1mg and use it vaginally before bed. I sleep like a baby. 😊
i'm mortified he supports synthetic hormone therapy over bio, based on the arguement of quality control. this is horrrrrific animal abuse. shocked.
Hormones are powerful. Getting varying dosages is awful. I agree with him. I am very sensitive to changes, I can't use any generic from any company.
If you understand chemistry, the molecules are identical regardless of the source. Bioidentical 17 beta estradiol can be synthetically derived.
😂true
It's so ridiculous that these old men in the Whi , are making decisions about womens health.
I do agree with you, I am shocked how confident he is in his statements. He needs to do more research before claiming something like this.
How ridiculous is it that female gynecologist didn't read the WHI study critically and denied their female patients proper care?
Dr. Bluming 's book is excellent. He is not the problem. He is pointing out the problem. Did you not listen to this before you commented?
If you read the original study, it was clear the breast cancer finding was not statically relevant. They wanted to make a big splash and did that stupid media release. My mother was affected by these dishonest researchers. Meanwhile, all the doctors, most of whom are women (gynecologists) instead of critically going thru that study, just believed the garbage they were told. Zero critical thinking. They didn't fight for women. Women behaved emotionally and just believed this garbage. Until we realize nobody is coming to save us we will continue to be manipulated to our detriment. It is not difficult yo read and understand studies,but you need some statistical background and training. And the ability to think critically.