The True Story of David Sinclair's Longevity Lie
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- Опубликовано: 3 фев 2025
- The Harvard geneticist sold a fake miracle pill to GlaxoSmithKline for $720,000,000, and now wants the world to believe that he has discovered a new immortality molecule.
Everyone wants to live a long and healthy life. No one wants to die. The oldest scam in history is the longevity lie. The first writing recorded on Sumerian clay tablets recounts the story of Gilgamesh’s failed quest to bring his friend back from the dead. The immutable fact of mortality has dogged human kind since its very beginning. And yet every age has brought with it its own crop of magicians, alchemists and scientists promising eternal life. Their pitch is always the same: everyone who came before them was a charlatan, but they have the secret sauce.
The most famous longevity grifter of our age is no different. If you’ve ever heard a news story that a glass of red wine might make you live longer, it was because of his groundbreaking research. Harvard geneticist David Sinclair is one of the most decorated scientists on the planet. He’s listed as an author on more than 500 papers, his work has been cited more than 96,000 times and he holds 50 patents. He was the editor of the journal Aging.
Resume aside, David Sinclair is no different than any other health grifter throughout the ages, and great fortunes have been squandered in pursuit of his “science.” In this week’s video I dive into his 25 year history of scientific mistakes, lies and fraud. I show how he used disproven research on the chemical “resveratrol” to sell a best selling book and, ultimately, a company to the pharmaceutical drug maker GlaxoSmithKlein for $720,000,000. Two years after the sale, the research was proven to not work, and Sinclair became one of the richest scientists in America. Now, ten years after that work fell apart, Sinclair is at it again selling the idea of a new immortality molecule called NMN.
This video took me three weeks to put together, but it was worth the wait.
CORRECTIONS: Robert Sclafani, Ph.D. is a professor emeritus at University of Colorado School of Medicine in Aurora, not CU-Boulder as stated in this video. Additionally, his meeting with David Sinclair and the member of the Nobel Prize committee occurred in Colorado, not Europe. More about Sclafani here: medschool.cuan...
Additional Resources:
@DrBradStanfield "The David Sinclair $720 Million Train Wreck!": • The David Sinclair $72...
@HealthnewsOfficial "David Sinclair EXPOSED: REAL Truth Behind His Controversial Claims" • David Sinclair EXPOSED...
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Gay.
also ....move the teleprompter a bit further away, it really looks silly looking left to right constantly like that.
Hi Scott - Great Vid. I always thought ONNIT was founded and sold by Aubrey Marcus...
@@TwisterTornado Interesting advice. Will think on it.
@@sgcarney Fraud is a very serious word.
The best longevity ideas so far are getting enough sleep and regular exercise, eating healthy food and drinking water, avoiding cigarettes, alcohol and drugs, driving responsibly, avoiding crime so you stay out of prison, avoiding arguments that lead to fights, worrying creatively rather than extensively, doing creative activities and helping others while not getting used, spending time with friends, living a meaningful life, feeling inspired by something or someone worthwhile, being interested in a fair few things AND it's also important to have a good superannuation plan. Start paying into it while you're young. Keep paying into it until you retire and then you can have quality of life in your old age.
@@tracesprite6078 Facts
Bro
Yes, somewhat sadly, these are the only things that have been shown to work
But high NAD+ level is good and NMN increases NAD+ level, both are pretty concrete.
People just don't care, you see how they run ing to turkey to get body work and then dying under the operation. Most don't gell their parents where they went, only when they come back and have to be rush to th hospital wit sepsis.
The secret of longevity is deleting all social media apps.
Oh for real, i deleted tiktok and Instagram but i still have some people contacting me on Facebook so i downloaded it again... Will probably delete again soon
You know that Sinclair wrote a book, right? 😂
RUclips is social media too. Especially if engaging in the comments section.
LOL! I hate them!😆😆
Once again, the secret to longevity is your credit card number.
100%
@@watcherworld5873 good point, that's why I paid by check.
Lmao
I found a 'Debit' card, will that twerk ?
@@AdamShaiken it will, debit is liquid cash
The two best things you can do to improve your health and extend your life is to stop consuming processed foods and get regular vigorous exercise. Both are free. Your body does not suffer from a deficiency of pills and potions.
Fasting when sick has entered the chat.
Exactly ,this is what I have been doing for years and it works wonders. Very simple.You just need the will to do it.
I'll add limiting the amount of alcohol and sugar you drink, getting enough sleep, not smoking. Living relatively stress free helps too
Science today is more advanced than your garden variety of wisdom.
mmm, what are processed foods?
Thank you so much for this one. I needed it. I'd recently read Sinclair's book, tuned into his work, and bought the recommended supplements. I really thought I was on safe ground because of his Harvard position, and peer reviewed published papers. It's true what the woman at the end said, it's a huge blow to public confidence in science. It is to me. Yet another level of skepticism and distrust added to my neural network. But thank you Scott for the great work.
btw, you earned me as a subscriber today.
@PatrickCombs
Q
I tried in half the recommended amount
The combination of
#1 NMN and
#2 Resveratrol
My skin began clearing up on my face and I noticed that I had more energy throughout the day.
I ordered more products but none of the products are from companies or advertisers having affiliation with Dr. Sinclair. I read thoroughly the research papers in order to see what quantity is needed for affective results.
Q
@@TheFoxisintheHouse Hi, I also take NMN and I can confirm about having higher enegry levels. I aslo regenerate quicker. Also I stopped going bald.
The Shaolin monk Dr. Chris Dorn wrote in his book BEWATER, Scepticism comes from hate (Not wanting) and Greed (Wanting) and is a mental sickness.
All these online influencers are in to make money including scott carney. Intake what anyone says with a grain of salt.
Never trust a longevity guy who dyes his hair, has laminates on his teeth, uses filler and Botox on his face and uses a beautification filter whenever he does any vids.
Sounds like Bryan Johnson also.
@@monicalatvenas1348 because I know them to be true
@@monicalatvenas1348 Old photos of Sinclair show his appearance has “miraculously” changed. You don't really think that's the effect of resveratrol, do you?
Also never trust anyone who still pimps bad medicine.
Also never trust a doctor who still defends covid 'vaccines'
Forget David Sinclair, Peter Attia, Bryan Johnson, Paula Saladino or Andrew Hubermans longevity protocol- I want Jane Goodall’s longevity protocol.
one of them (Bryan Johnson) isn't like the others
What a list of wealthy losers.
You can't call them losers. They're crooks, but they're not losers. You probably are one in comparison though.
@@electricpeach7231 Reject modernity, return to monke. :)
Protocol sounds so pretentious.
The bigger question: Why are places like Stanford and Harvard legitimizing people like Huberman and Sinclair?
I'm guessing ££££$$$$$€€€€¥¥¥¥ Everything's a business now and someone somewhere is getting screwed over and another is getting a cut of the profits. Integrity is nice but it's money that really matters. Terribly sad, maybe it's always been this way but we're just more aware of it now?
They are sliding in their legitimacy at an accelerating rate.
You weren't listening either. Listen again.
@@joshnova9163 what's wrong with Huberman?
Everything is about money, it's 2024 already, time to wake up, boy.
My paternal grandmother lived to be 110 and was on no meds. She lost her eyesight around 100 and really didn't want to live anymore. She didn't try to end her life or anything, just complained a lot because what she spent her time on was reading and doing needle point so that was lost. The only thing I remember her doing for longevity is drinking a lot of hot water. At least once a day she would put a teaspoon of honey and a teaspoon of apple cider vinegar in it. She also ate a lot of grease, she like to wipe out a cast iron skillet which had fried a bunch of meat in it, with a piece of bread and then she would eat the bread. She also put gravy on everything. I personally think grease is where it's at ;-)
C15 is the new thing and it's in animal fat.
Your grandmother got to her age by pure chance. Everyone else who isn't so lucky has to rely on meds. Your argument is the equivalent of saying I know a lottery winner who never worked so working is useless for making money.
Food and even lifestyle are highly overrated for lifespan. Your inherited genes will determine most of it. Can you live a extra decade with great diet and lifestyle? Most likely, yes. But when looking at (super)centenarians, that live 2-4 decades extra compared to the average lifespan. That's purely genetic. Most likely your grandmothers side of the family will live long lives. Obviously, there are many factors like stress, accidents or a virus that can shortcut it.
@@KasKade7 i partially disagree on diet and lifestyle importance, because those things can be very wrong in modern society, so they are indeed pretty important, i agree that most likely you are not getting to 100 yo just because of them, but with bad habits is likely you die young in today already toxic world
@@volos_olympus I'm not gving any health advice, just saying what my g'ma did. Med's do more harm than good. If you are relying on medication to live, good luck.
I am 61 years old and when I take NMN I walk 5 miles a day, when I stop taking it I stop taking walks. A friend of mine had 4 strokes and was laid up in a chair for weeks. I sent him some NMN and the next day he was out puttering around in the yard. Hasn't has a stroke since. David Sinclair's NMN is one of the only supplements with a noticeable effect. You can't debunk NMN for me. I would love to see the science on why NMN doesn't work. And why is the US Military doing studies on NMN as we speak. Why is NMN present in every cell in our body? A few jealous and petty doctors who prescribe poison every day with hundreds of side effects are mad they have not gotten rich on something they discovered. Resveratrol may not be what it was hyped to be but it is still a player in longevity even as a possible antagonist. Quack, jealous doctors getting rich off the backs of real scientists, that is the problem here...
this is obviously a placebo effect!
@@tuanpham-vv3qj You think I would know the difference of a placebo 4 years? I take 14 supplements a day. NMN is the only supplement I FEEL when it take it.
VERY remarkable indeed. I wonder why this comment has not been erased . . .
Dont forget our valuable GENETIC heritage ! Jeanne Calment NEVER took NMN and lived up to 120 years !
Good thing you are healthy and fit. But health isn't only determined by one factor. So you can't just attribute your success to one supplement, when other factors weren't taking in consideration. The doctors aren't jealous, they just doing their job as a member of the scientific community. There are so many bullshitters out there, just don't get me started on homeopathy.
I'm immortal. Haven't died in years. My secret is not dying.
Ba ha, you funny, @RatedX29!
@@RatedX29 Can you teach me?
Carlos Casteneda also told his Cult followers that dying was weakness and not for him. After he discreetly passed, his close, female staffers apparently all disappeared themselves, (maybe out of embarrassment).
I have the same gift (so far).
I haven't died all 50 years. I must have the same power as you wield 😮
TED Talks are medium for grifters. (this guy, Elizabeth Holms, etc.). In no way should giving a TED talk translate to any sort of scientific prestige or accredidation
Agree.
Yeah, like the actual research... which people could just look at instead of this attention seeking shite.
So go on a TED talk and epxlain your theory
The NMN resveratrol combo got my dads knees working again
What's NMN, please?
The truth of the matter is that there are at least twenty clinical trials with NMN, NR, NAD published on top-class medical journals where results are positive.
Yeah NMN works really well... Just haters here...
@@catsnmi270 Nicotinamide Mononucleotide, precursor to get NAD produced in our body.
and aspirin
I have been doing this for 2 yes it has changed my life you must change your lifestyle as well I am so healthy I ride a pushbike I am67yrs old I am more active and healthy then my early 20s I support Dr Sinclair he has changed my life Don knock it till you try it Helen from Australia
I have no personal experience with Sinclare supplements, so I cannot speak to their efficacy. However, I believe that a more productive approach would be to focus on the fundamental flaws in the Sinclare narrative and demonstrate how it is unscientific. Otherwise, this video has no value. This approach would be more conducive to advancing the scientific discourse
MMN, in defense…. I put my 84-year-old mother on this molecule in two 500 mg doses per day. She went from having to use a walker and holding on furniture as she moved throughout the house to being able to walk again independently. This over period of 18 months. She gained weight from 85 pounds up to 95 pounds,she says she can taste her food again. She often forgets her hearing aids because her hearing has improved to the point where she really doesn’t need them anymore. She said she feels great, so anecdotal but important.
I remember being blinded by Sinclair's book and touting it to people. I took detailed notes to understand the mechanisms and tried to find all the ingredients. Always found it strange that DS never said where to get NMN and the other key ingredients. Damn. I got bamboozled. Thank you, Scott.
It’s just so easy to get hoodwinked. Been guilty of it myself a few times.
Thanks for your honesty. I was bamboozled by cryptocurren ies😂
How can you not find NMN? A simple Google search should yield you plenty of sources. It is really not hard to get.
@@cajampa I'm referring to where exactly Sinclair got it; which Scott references this lack of source as a flag during this video.
@@pbfoley Who cares where he got it. I mean I get that you for some reason do. But I don't. I wanted to use it, so I bought some from a place that could provide analysis that showed it stuff was genuine. And it works great. Why missing out because you got hung up on whatever source he got it from.
The man is a scammer.
But that doesn't mean that the substance itself does not work as a health boost. Because it does, that is why it is selling. And many of those who tries it keep using it.
Eat real clean food, once or twice a day only, sleep 7hrs, stay active, avoid sugar, develop a stress management protocol for yourself, forget the past… and live long!
This is so concerning; we hold these institutions like Harvard and Stanford with great reverence. Having grifters like Huberman and Sinclair really reduces the credibility of these institutions
Sometimes - i think it’s more grifters from these institutions leveraging the names of their institutions but isn’t representative of the thousands of real scientists and academics with integrity from those same institutions . I’m surprised there aren’t more cases of grifters from these institutions given how easy it would be
@VuNguyen-fv5jl well yeah. What's the problem with Huberman other than attempting to be a wellness polymath? His basic tenants are pretty good.
@@Jammoudagree. Quite worrying. I guess we have to keep
In mind these institutions are in fact private organisations. That makes them vulnerable to this kind of grift.
bringing sinclair and huberman so close together demonstrates that you do not understand anything what is going on
Nobody at Harvard (the hospital, not the university, btw) respects Sinclair.
Dr. Carney, I know a biologist who knows firsthand about misconduct about at one of David Sinclair’s companies relating to creating a hostile work environment and making physical threats. David Sinclair, at the least, tacitly accepts this. May my friend tell you about this? I Instagram-messaged you. The message went into your requests inbox instead of your main one.
Definitely interested.
Viewers like you can support this channel! I make money on YT ads and I have a substack and patreon. I have never taken a sponsorship so far because I'm too picky.
Labor and employment attorneys exist. Document document document.
Is Scott a doctor??
@@mimisides You can bet Sinkliar doesn't understand what he says either.
1) I don't like the strawmanning going on in the video introduction and description ("wants the world to believe that he has discovered a new immortality molecule"). Sinclair never claimed that some single molecule/drug he has discovered confers immortality, that's a flat-out misrepresentation.
2) From the video description: "I show how he used disproven research on the chemical “resveratrol” to sell a best selling book and, ultimately, a company to the pharmaceutical drug maker GlaxoSmithKlein for $720,000,000." - It's the other way around. Sinclair sold the company in 2007. The book only came out in 2019.
3) The copious use of emotional appeals - words like "grift" and "lie" - from the outset, ironically, make you sound yellow-pressey. Objective reporting should be more aloof, or at least save terms of this sort for the end, when you've made your case and their use is justified.
I've been meaning to read your book "Red Market" for a while now, but given your apparently sloppy and tendentious approach to reporting, maybe I won't.
P.S. I'm not a Sinclair fan. He's recently been ostracized by his peers, ostensibly deservedly. But his science is still possibly better than your journalism.
Did you watch the video? Or just read the description?
@@sgcarney I read the description and watched the 1st minute of the vid. The aforementioned issues jumped out at me as a strong indicator that this isn't an accurate piece of reporting, so I'm disinclined to watch the rest. (Unfortunately - because a objective-yet-critical piece on Sinclair would interest me a lot.)
@@sgcarney Watched it. Your piece is riddled with distortions, non sequiturs and logical fallacies. Many of your claims/conclusions are either tenuously connected to or blatantly misrepresent the very pics/clips you show as evidence. There do seem to be a few fascinating stories lurking in all this, but I guess they'll be the province of a more qualified investigator. Sorry.
I tend to agree with you.
By constantly using words like 'grift', the video is priming the audience's brains to draw the conclusion that he wants it to draw.
In the end, all he has is basically one professor vouching for his claims that Sinclair is a fraud.
Also, the resveratrol claim isn't the only thing Sinclair promotes. He also promotes intermittent fasting and cold showers, which are ideas that earn him zero pennies. This video doesn't address the science behind that.
Finally, for a video that purports to be a piece of journalism, that final bit on the Nobel prize rings like silly 'high school mean girl' type gossip.
The presenter smiles like he's enjoying this bashing a bit too much.
@@studentofspacetime 1) "By constantly using words like 'grift', the video is priming the audience's brains to draw the conclusion that he wants it to draw." - Yes, and I wouldn't really harp on this point if Scott Carney was your average clickbaity RUclipsr not pretending to do serious journalism, - excessive emotional appeals would be par for the course, - but Mr. Carney's credentials as per his Website bio, etc. seem to establish him as a (near-)professional journalist, who just happens to have a RUclips channel. Thus I had higher expectations.
2) "that final bit on the Nobel prize rings like silly 'high school mean girl' type gossip." - Oh yeah. Sinclair's networking - which I would expect all sociable scientists are doing - is painted in the most unfavorable light possible. Indeed, with a kind of mocking, slightly childish glee, as you imply.
But I honestly had so much issues with this video pertaining to its factual content. Writing out a fully detailed critique would just take too long, and I can't even be certain the author would see it. Just a couple of examples:
- “The Sir2 theory was junk.” (Mr. Carney) - Not so fast, it’s not that simple. A scientific article from 2014 called “The controversial world of sirtuins” and published in “Drug Discovery Today: Technologies” provides a nice and relatively comprehensive overview of the historical studies of sirtuins and the controversies around them. The conclusion? “Sirtuins (can) be therapeutic targets in future medicine… Despite so many controversies, mammalian sirtuins have been clearly shown as a class of critical factors regulating many cellular processes, playing important functions in diverse tissues and systems… However, the complexity of activities of sirtuins, and their widespread roles and activities, increases the difficulties in determining how best to modulate them therapeutically.” The upshot is that a) sirtuins are definitely a key player in human biochemistry, b) we don’t understand either it or them well-enough yet to make conclusive statements or develop targeted therapies.
Incidentally, the article’s author, a Mr. Dang, summarizes the goings-on around that study by Matt Kaeberlein mentioned in the video. Sure enough, several studies in Europe didn’t replicate its results. But then another study did achieve somewhat similar results. The experimenters on both sides are still arguing about the details, and the issue is not quite resolved.
- Re: the claim that Sinclair’s blocked "all the companies that were selling NMN" from the market. - However, the very document Mr. Carney displays on-screen in connection with this claim states clearly that this does not apply to the companies who’d already been selling such products before Sinclair’s team filed their paperwork. Also, a perfunctory search on Wiki shows that companies had been selling NAD activators (which is what NMN is) as supplements well before Sinclair put the spotlight on NMN.
So weird how he was everywhere, and then nowhere...
Not really when you consider that he is yet another jewish personality astroturfed into popularity by YT like Huberman, Lex Friedman, Max Lugavere and Tim Ferriss.
@@AlexQoelet it doesn't have anything to do with him being Jewish, ffs
@@AlexQoelet🥱
kinda does
@@gregtheflyingwhale it really doesn't. Ted postol is Jewish and an MIT professor and you cant mention his name in polite society because he exposes the liars. Bigotry is dumb.
I was a grad student in the Guarente Lab while both Sinclair and Kaberlein were there. It was common knowledge in there that you needed to keep an eye on your project if Sinclair thought it was interesting!
@@chrisarmstrong3061 can you elaborate on what to keep an eye for? Just curious. You know, Dr Kaberlein also has a RUclips channel about longevity science. How much do you think his is credible? More than Dr Sinclair I guess🤣
@@lumanliu8457 , when I was a student there we called Sinclair "the Shahk" (emphasis on the Australian accent). He was extremely aggressive and would start doing work on your project without knowing. This happened multiple times. His post-doc work was not on Sir2 but as soon as our work was able to find enzyme activity, suddenly he was on the Sir2 train. When he was leaving the lab to start his lab at Harvard, he and Lenny (Guarante, my graduate advisor) agreed on which projects he would take from the lab, a normal part of the process when starting a new lab, and I don't think Sir2 was supposed to be part of the mix.
As for Matt Kaberlein, from a personal standpoint, I was not particularly close to him even though we overlapped for a fair amount of time. I was actually much friendlier with Dave Sinclair, and we would frequently go out as part of a group for a drink after work. That being said, Matt was much more rigorous than Dave in his science and is typically much more careful in his claims now.
Both Matt and Dave are extremely smart and extremely driven. This is why they have been so successful. My time or experience with him would not lead me to believe that Dave is intentionally being dishonest, but more that he would convince himself that his models were correct and in the process cut corners to get a major publication. Oh and the anecdote about the Nobel Prize DEFINITELY rings true.
@@chrisarmstrong3061 Details, please!
Please do a video on mushroom supplements like Mud Wtr, Paul Stamets, etc. There are so many grand claims about mushrooms/fungi, it would be much appreciated to have some light shed on this!
@@j_frosty Well they are being used and studied a lot but. They are very very usefull for many many diseases but their effect can be unpredictable due to making way too many shit at once. You may get rid of your allergies anxiety autoimmune disorder,long covid, depression etc or it may make your life miserable(mostly in high dosages) and make the things you want to get of worse.
Mushrooms have long been used as healing, medicine and for a strong immune system..Forget the hypes...but mushrooms are real food!!
here in Kenya, dr Sinclair fans looked at Sinclair's science..it wasn't reproducible, falsifiable nor held up to exhaustive investigative scientific inquiry. we don't care about his big names, just the merits of the science. nothing more.
people must now hold up every researcher's claims to such exhaustive scientific scrutiny.
😂😂😂😂😂😂
Yes Kenya - the third world country with the healthiest people in the world lol
@@Len1977gt well, it seems to have at least one healthy, ethical scientist.
@@Len1977gt my apologies, being american must be tough
The big question is: Is there still hope for longevity science after prominent figures like David Sinclair have been exposed?
Despite the misleading claims of some scientists, I believe we shouldn't abandon the quest to better understand ageing and potentially discover effective ways to slow or even reverse it.
This pursuit isn't immoral-in fact, it’s a noble endeavour.
However, it's disheartening when influential scientists, such as those from Harvard, betray the hope that so many of us secretly hold.
It’s a good question. Humans are living longer every generation. But grifters are multiplying at a higher rate than the science. We will see.
@@sgcarney
We should inspire more young people to delve into the science of aging and promote wider public engagement on this critical subject. While advancements in AI and the potential rise of AGI don't guarantee breakthroughs, they offer a promising avenue for progress and hope in the field.
Given that the basics of longevity that you can control are Exercise,Diet,Sleep/Recovery then yes there's heaps to do that doesn't even have to involve any supplements. These things do the heavy lifting, however, some people are lazy and would like to just take a pill. They can be gullible to snake oil salesmen. Some supplements have definite benefits but they are more so in the realm of 1-3% improvement compared to the 30-50% from exercising etc
While this video might suggest otherwise, David Sinclair is still very much active in longevity research. Contrary to the claim that he has been "exposed" and is no longer contributing to science, Sinclair continues to work on cutting-edge projects, including epigenetic reprogramming, which shows promise in reversing aspects of aging. The field of longevity is far from stalled; in fact, advancements in AI are accelerating research, allowing us to explore new possibilities more rapidly than ever before.Rather than dismissing the entire field because of perceived failings by prominent figures, it’s crucial to recognize that the pursuit of understanding and potentially reversing aging is a noble and ongoing endeavor. The scientific community, including Sinclair, is dedicated to this work-perhaps even more so than those who focus on discrediting others and make a good living from doing so. The hope for longevity science isn't just alive; it's thriving.
@@GraftonPrimaryvideo
I agree that exercise, diet, sleep, and stress management are crucial for improving health span, but they can only take us so far. Personally, I believe the human lifespan is too short, and if we’re going to extend it beyond 120 years, science will be the key to achieving that. However, I’m concerned that snake oil salesmen are damaging the reputation of genuine scientists who are working diligently to solve the complex challenges of aging.
I've been running an online campaign against Sinclair for years. Still am. This man IS a fraud.
Sinclair or Carney?
@@grannygoes7882 Sinclair.
Whew!
How have we missed each other? I've been doing the same.
@@richardbreeze7898 how can we help to signal boost? Please drop the name of the campaign or link
This can be a bit misleading because Dr Sinclair didn't say u could achieve immortality with resveratrol or NMN. These things could improve heathspan/lifespan slightly but it's obviously not the fontain of youth.
The most important thing he says is regarding partial reprogramming.
This indeed has potential to be one of the things needed for immortality when combined with other treatments
Correct. He didn't say immortality. The reference was to the immortality grift. Sorry if that was confusing.
On the other hand, immortality is not impossible. It's not against any law of science such as the second law of thermodynamics.
@@diogoafonsoyt I have listened to him for years you absolutely implied it as he made the rounds of podcasts, it's painfully obvious what he was saying without actually saying it. At one point I believe the market was going crazy as Resveritol became nearly unobtainable. And he had the market cornered on the production of it through the supplement company he owns.
Dr chaffee interviewed an 80 year old rancher from canada, she looked 40. That's real anti aging
Do you remember her name? I cannot find
@@gqas1247 Maggie White
Dr chaffee carnivore diet?
Maaan, that music in the background to make the video more emotional was terrible addition xD great reporting, though!
Man I’m not even subscribed but I just see banger after banger. How can I not sub.
Welcome aboard!
Fact, about to sub
would you be willing to debate Sinclair or Attia and Co?
Would really boost your channel and reach with proper impartial mods
How did I not know about your channel until today!?! You and Chris Macaskill (Plant Chompers you tube channel), are my heroes.
I love watching Chris at Plant Chompers too!
plant chomper is a propagandist. He got absolutely crushed by professor Bart Kay. Many times. Still too afraid to accept Barts debate challenge.
I borrowed Longevity from my library. Some of it sounded good but then there were parts James Randi would’ve called woo woo.
My sixth sense told me not to take him seriously.
@@ingenuity296 yeah...mine too
I've never watched him
Yeah gave me creepy vibes immediately. Bet there’s some serious skeletons hiding…
@@deBRANNETreu Just the regular soulless beta selloff
@@ingenuity296 I also saw his videos and read his book and felt he was a fraud.
Same here. I'm Australian and noticed his phoney half American accent. That usually indicates something's wrong. I still don't know why some of us do that.
Hey Scott. So RUclips suggested your video on AG1. And I've watched about 8 of your other videos back to back.
You have a new subscriber. For the most part you most certainly have opened my eyes as to what we are told by "influencers" and what the truth is.
I'm really looking forward to this upcoming video. The truth is what technology has caused humanity to lose most of all. And I feel you are truthful in your journalistic approach to exposing lies. But will also be cautious to make sure I check when big pharma approaches you 😉
Thanks for signing up! I love it when people dig into my catalogue. Some of it is pretty good. And big pharma is welcome to become a premium subscriber like everyone else!
Overall, humanity (and animals) benefit greatly from big pharma and even small and middling pharma - it's the executives, CEOs and some unethical investors who give it a bad marketing direction and name. The science and scientists are great and very different to the former.
He deals on small fry though, and makes money off popular names. He doesn’t cover anything that’s far reaching or meaningful. He’s riding their coattails, make no mistake 😂
Stopped listening to Sinclair when he blocked dr stanfield. An honest person doesn’t block, but engages and explains.
100%
@@dinapawlow1622 Stanfield sells his own brand pills….
@@dinapawlow1622 👏👏
Me too
@@dinapawlow1622 lex Friedman
For some reason, unknown to us mere mortals, it is our duty to die, since we were lucky enough to be born. Life is such an amazing experience, that many can’t let go of it when the time comes. There is no way out of death, “Just not today”.
@@DrivingMaskina Well-said!
Death is nature's way of pressing the refresh button.
I got a Tony Robbins ad while watching this, it gave me a great giggle, maybe I’ll get an AG1 ad next. This is awesome work, keep it up!
Tack on a wim hof course and you get a prize.
@@sgcarney I don’t want that prize!
Tony Robbins ad for me, too
I love Sclafani's office ;-) To Scott: please reduce the movie music a bit if you can, it's mostly distracting and not necessary to add "fake drama" IMHO. The facts and your telling speak enough already. Thanks for making this content. I'm a total layperson, and still trying to make up my mind on the whole NMN debate.
David Sinclair promoted non pharmaceutical interventions, such as: calorie restriction, exercise, rest, intermittent fasting, heat/cold exposure.
He did take things like metformin, reveratrol, NMN., etc but he never promoted it as far as I know.
I have been using NMN for the last 3 years, I'm 68 years old and feel energetic! My prostate stops bothering me at night, I sleep well and it assists me in feeling good. you can continue to say it is fraud. for me, it worked so well
I have been using nmn since 2019
Cold showers every morning will do more. Really, tried and convinced. My friends say the same.
So it fixes prostatic hyperplasia too 😅.
@@hanamanova5514 I do both.
Cold showers and NMN.
If you want real health and continually improving potential you don't do one thing. You stack many many things that gives you more health for a much greater benefit.
@@Fomites it makes me to fill better, and I m not joking or looking for excuses for using NMN, it looks that is a trend to fight with Sinkelr. I m sharing my personal experience and you can lough about it or not, I m not selling any NMN and I share my experience.
I’m so glad that you are coming for this guy…
Proud to have been here since your first video. Keeps getting better and better. It's hard to wait for a next book from one of your favorite authors. But when the author starts making videos... Game changer. Looking forward to the next one. Thanks a bunch for the awesome content.
Can't wait to see a deep dive on Bryan Johnson. You edit your own videos btw right? I like the dramatic ambient sounds at 7:00 ish. I encountered Sinclair, as well as Wim Hof, Bryan Johnson, Andrew Huberman, all around the same time, 2-3yrs ago. At the time I was in a serious personal life crisis and they struck me as diamonds in the rough. But now I see I too was one of the vulnerable they prey on. I still learned MUCH through them, but not necessarily the lessons they are trying to impart... more like critical thinking to find charlatans.
Yes! I want to see this too! He's developing a cult like following on his RUclips.
I have no clue who is right, who is wrong, BUT Bryan Johnson and Sinclaire are all fishy to me, they are all profit driven, and as spiritual being we all are, we know they are fraud in our mind, but very hard to justify it, BTW, I do most of the stuff that Bryan Johnson is doing ( tons of supplements, quality sleep, cold plung, red light /suana , everything that could possiblly make me health, you name it, BUT, am I feeling so much better? NOT AT ALL , i feel maybe 5% better if no placebo ? that's another reason I'm not sure those hype online would be liable at all, and you also see ads like like aderall but better selling metherlyn blue or some off the counter meds , let me know tell, nothing like aderall, Addreall works the best for ADHD and ppl who wants to be productive, BUT of course it is a drug that we all should avoid or under the guidance from doctors , too many scams, too many misleading information nowaday, we can trust nobody.
Lol - I wrote the same thing after watching this video. I am not appreciated for questioning him on Reddit.
@@zachhoy i came into their videos in the similar situation, I was so into these until I questioned myself over and over, and it makes no sense, I think we human supposed to leave this world, don't tell me "don't die", sounds cool, sounds eye catching, BUT the universe determines how long we are here, I truly believe there are so much we human don't know, we are here to experience, to fulfil some higher purpose, good or bad, just let it happen, just let it grow in a healthy way, do not try too hard
I was a BP5000 participant but he lost me when he introduced his own product line. Turns out it was just the longest and most expensive funnel in history 😮
I’m curious, because I was feeling very old and achy - ALL the time. I started taking NMN and Resveratrol with TMG every other day for about 4+ years. I have never felt better and I have seen substantial differences! I don’t take a lot, but add it in 5 out of the 7 days. My husband was skeptical, but I had him take the supplement stack for 2 weeks and he gained his energy back and much less pain in his joints. I am a firm believer there are many benefits and they do help restore decreased NAD levels.
A friend of mine also swears by it. He started taking it a while ago and he looks younger and better than 10 years ago even, he looks great! He also said that he felt better, less old and achy, exactly what you were saying Jennifer. Granted, he´s also taking other supplements, but says that NMN is the game changer and he notices the difference when there´s a period when he hasn´t taken it (it´s quite expensive) and starts taking it again. Based on his experience, I have also bought some, and felt gutted by what is being said in this video, but your comment has given me hope, and so I guess I will be another human guinea pig. I will at least keep taking it until what I bought is finished and then re-evaluate the situation.
I've bee taking NMN for 2½ years now. I never want to miss it again. I feel renewed.
@@soraiya2065 That’s great. I think everyone may be different. I also incorporate Sirt6 from DoNotAge and apigenin in the evening 75mg. And NAC once a week
I tried same protocols and no real results after years.
Hard to say.
But I got fantastic improvements when I changed my sleep pattern and started doing regular exercises.
@@hanamanova5514 Thanks for ur input. Interesting to see what people who've tried it have experienced. Maybe it works for some and not for others. Maybe it's the brand. Maybe it's placebo effect! Haha.
I'm so glad someone helps me keep my gullibility in check. Where is that other documentary you mentioned
Check out my charlatans and grifters playlist.
@@sgcarneyjust did. Can hardly wait!!!
@mimisides oh...I think it's not so complex. Scientist sees a chance to make a lot of money off people who want to believe...rather than a little money doing legitimate research with other cautious scientists. Scientist creates a product and touts it to the rubes. Scientist rakes in money. What's complicated?
You should look into Bryan Johnson a bit more. Insanely weird, always invites hate comments - yet when someone scientifically critiques him they get blocked faster than a speeding bullet.
I'm one of them!!!
@@maarten7 Yep, I got banned from his subreddit (albeit by his mods) for critiquing his claims. Bryan himself has banned scientists to critique him.
@@James1050 One has to be suspicious when someone - making claims he can't back-up - is so defensive.
Having extensive cosmetic work done doesn't help his claims, either.
In a nutshell, what were y'all critiques of Brian Johnson? (I can always smell untrustworthy salesperson a mile away, but I dont have facts)
Just look at him. What a bad representative of men.
The argument... "We don't agree with his findings. And 'ha ha' those brains aren't thinking".
Literally NO ARGUMENT was made in this entire piece.
These influences seem to age at least as fast as anyone else. You can only beat (Premature) aging by healthy levels of social engagement, healthy exercise, and avoiding anything that promotes inflammation.
This is what I have noticed too.
They claim a lot of anti age benefits, for people who look at least as old as they are.
Dynamite report. Important. Scary. My God! People from Harvard and Stanford involved. A few years ago I was thinking of doing a YT video on Sinclair because his experiments on mice did not make sense to me. I knew that Glaxo, after spending all that money, eventually decided not to market Sinclair's products. I had no idea of the immense fortune he made. Thanks for a great report.
Thanks!
Another great video. About 5 years ago I was a speaker at Raadfest (see Maryam Margolies “What Happens When We Die?” 37:00). While on stage, I asked “who wants to live forever?“ Entire audience went crazy. “We do!” They all shouted. “Why?” I yelled back. (stunned silence.) “ Why would you want to live forever when everyone around you is an asshole?“ The point I was trying to make was the folly of pursuing immortality before pursuing spiritual development. It was lost on that group.
Well said. Even Greek and Chinese have similar arguments like you. Meanless extension of low quality of life has no point - esp. at the expense of investment of innocent public. A life lived without integrity and authenticity is equally tragic and pitiful.❤ A health society should always has more than one voice.
if he was able to "reverse aging", he would have won a nobel prize in science. The fact that he doesn't have one, speaks volumes
He has demonstrated a reverse in aging. It needs alot of refining and far more time for it to be spectacular in its results for humans. It's a case of degrees worth of anti aging.
@@paulharrisonadventuregearm5457
No way to reverse aging, damage to DNA is not reversible
@@SmashBrosBrawl totally wrong on that!!! Completely wrong! There are specific enzymes and repair mechanisms that move within our cells to repair damage
He’s never claimed to have solved the aging issue. It’s ongoing research. He has doubled the lifespan of mice and whilst this doesn’t necessarily translate to humans it is surely worth continued research.
@@SmashBrosBrawl LOL Sinclair is a fraud, but you’re just as bad as he is. DNA damage can totally be reversed. Both extreme sides of this aging debate are just as bad as the other extreme.
Very well done.
Thank you.
Please keep up your great work, hard to find real journalism these days.
Have read some of Davids books and I began to see some problems in regards to other serious books about this interesting subject - so this video is really refreshing and interesting
We live in a world where the experts in every field are turning on each other. How can we trust anyone
Try yourself.
Thanks for your continued essential work Scott. We need this content more than ever, we desperately do. Appreciate you and please keep at it.
I appreciate that! More to come.
I'm eating M&Ms daily for years! Them being healthy is great news!
Lol 😅
Mmm MNM
Thanks for sharing this story, and helping to expose this guy, long overdue to shine the light of day on his practices
Finally watched the video. I couldn't join the live feed as I was working night shift. Thank you for Great journalism. I hope your channel grows more and more. The world might not know, how utterly important, the work that you do, is. Our eyes need to be opened to the lies and deceit that people pose just to get rich.
From 🇿🇦. Thank you
After seeing all your D&D books, I must say that I truly value your output more than I did before!
Love your productions. Seeing things through the critical lens is so important to bringing the truth to the surface. I'd be interested in knowing your thoughts on Bryan Johnson's Blueprint Protocol which seems to incorporate some of Sinclairs "philosophies."
Yeah. I should reach out to him.
Loving this channel Scott. Look fwd to new episodes. Please keep them coming! 👌🏻
Did he actually ever state why he claims NMN is bogus or it simply because his science buddies say they can’t duplicate the claims? I half listened to this while I was driving and not sure if I want to give it a second go… Because yeah sure, there are gonna be all sorts of bogus supplements that come from China but that doesn’t mean you can’t produce some quality products. I’m taking a product from Tru Niagen and I’m fan. 🙌🏻
excellent journalism and storytelling
I am no scientist, but I determine if something is true by trying it myself. I have tried vitamins, nootropics and nad, here is the results so far. After trying almost 10 different types of nootropics, at least for me, it doesn't work and I will not consuming any more in the future. But for nad, I will continue consuming it, what I have experienced is, I don't know if this is directly attributed to nad, but I notice my eyesight has become much clearer when I watch movies and when I am outside, it's like my eyes has become HD.
The first time I saw Sinclair was on Huberman. I thought to myself, this guy probably dyes his hair and makes sure to shave every day to look younger. Sure enough, he admitted to dying his hair later in the episode.
Won’t be long before you will be doing one of these about Bryan Johnson .
Thank you so much for having the courage to expose this type of charlatan. 👏🏻
Love your videos! Thanks so much for your investigative research
Glad you like them!
First time listener. Really liked it. One thing. A little less smug would be more effective.
I am fairly neutral and tried many supplements. I take resveratrol and NMN daily for 7 years. Missed maybe 20-30 days in total, mainly due to some travel. My wife started 4 years later. We are not easy to sway either way. I cannot say either way if it increased or decreased my age. But I can honestly say that all my muscle pains are gone and I can stretch the same way as I did in my 30s. And I am twice as old now. I stopped having periodic pinching heart aches that spooked me during frequent weight lifting for number of years. I attribute it to both supplements since my diet did not change much and it would be too much for placebo effect to numb my leg muscles and hide heart pains. Go figure..
Which brand do u use please
@@leonardzemlinsky7165 I use NMN, it’s one of the few supplements that seem to work. For me it took several weeks but I noticed a step change in my jogging, no pain. Extending life who knows, improving my quality of health and fitness definitely.
Fairly neutral but you take res for 7 years??
@@gqas1247 following
@@simonwiltshire7089 exactly. I will try anything that appears to have some chance of being true (or more). I take AKG, resveratrol, NMN, Fisetin, Berberin and 5-6 more not as regularly. I measure and evaluate and whatever seems to work I continue. I don’t really care that some folks see Sinclair as fraud. All I care about is that I can afford it and it seems to work for me and my wife. And until I stop feeling like in my 30-s I will continue taking it. And I wish all people online to feel like me and share their findings of whatever they take to help all of us feel better.
Surprised Scotts channel isn't bigger, love the videos!
It’s growing really fast right now. Let’s see where we are in a year!
Well, the one thing i would say to Sinclair is, extraordinary claims require extraordinary evidence. Lets see the evidence.
Helooks 20 yrs youbger and je does not reco a compNy to buy from
I spent thousands of pounds in the Resveratrol lie and later in the NMN lie. I am a fool. I want my money back.
I love that you have your D&D books on diplay there. Ravenloft and DarkSun! MY MAN! :D
I need to do a D&D video.
Scott you have opened my awareness, like a lost sheep looking to improve myself thank you for reminding me of critical thinking, I hope you get the support you are hoping for.
Super-excited for this one
Thank you Scott, I'm addicted to health podcasts so have been taken for a ride. There's no one you can trust, but just to say I appreciate you showing this information about Sinclair because I was about to buy some of his products. You're right they all go on each other's podcasts promoting one another like an old boys network. You want to believe in it and being loyal to them, believe in everything they're telling you!! Dr Campbell who is from the UK, he's not selling anything, he is sharing good information on health and other things.
If you want to live longer & healthier get sugar completely out of your life and only eat no more than 1500 calories a day. Eat like a diabetic. Gentle daily exercise is also critical. Emphasis is on daily. Being surrounded by family & friends also contributes to longevity.
So glad I found this channel. I feel the veil is lifted somewhat on stuff that we all consume. In the case of Sinclair though, I always felt his claims were suspicious given the lack of real proof to back them up
The secret to longevity is interacting with etheogens, specially at microdosing levels, practicing yoga & meditating at least 20 minutes a day. These r very simple & ridiculously obvious activities that have been literally ignored by almost the entire history of humanity due to aggressive campaigns of misinformation. Eternal life is definitely not guaranteed but I am absolutely sure that the human body can easily exceed a century of life looking incomprehensibly younger, more flexible & practically worry less. 3 very simple activities that if maintained on a daily basis will keep the bodies, again, hyper flexible, hyper aware & an without the number 1 cause of all illnesses ruminating at nauseum, worrying!
True. Long term stress is terrible for your health. Short term is good tho! I prefer harder exercise to yoga and meditation. There's a ton of proof behind it.
@@earx23 respecting that my brethren! Meditation can also b incorporated 3 times a week for only 20 minutes. However, psychedelics is the main key here. It opens the third eye dude. Nothing is ever the same
The thing I do admire about David Sinclair is that he takes the supplements that he advises others to take. As for his business dealings I really don't know.
You may very well be right concerning this individual, but you lost me early on by your obvious misrepresentation that he is claiming to deliver immortality.
That showed me that you are dishonest and so I can't be confident of anything you say is factually correct past that point and that was the point at which I stopped watching your video.
You should move into acting because obviously you can't do journalism.
It’s the immortality grift. He’s selling the dream.
@@sgcarney@sgcarney It may well be a grift. But he isn't selling immortality. That's ridiculous claim. And if you come right out of the box with a whole lot of hyperbolic nonsense, you destroy your credibility and I really can't be bothered.
As somebody who bought and read Sinclair's book and was very interested in his ideas, I'm glad we have a free flow of information and truth finds its way.
I read this story about a supercentenarian that lived to 120. She smoked until she was 115. The role of genetics cannot be underestimated
Outliers always exist. However playing percentages and risk, that is not likely to work out for most people. Genetics mean something but you'd be surprised how much you can fight genetics with exercise and diet.
@@GraftonPrimaryvideo great take
We don't judge on outliers. Smoking is causally linked to cancer, for every smoker who makes it over 100 probably about 50 die before 65. Everything I hear suggests that the role of genetics is largely overstated.
@@GraftonPrimaryvideo smoking is terrible for you, I would never condone it. What I'm saying is that there must be very strong genetic factors involved with those outliers, because not all of them lived super-healthy lives (like smoking for a...century). The average person should absolutely have good diet, exercise & sleep habits. But I think as a society we are too obsessed with living to these old ages, and then we use these "genetic outliers"/supercentenarians as examples of what average people should strive for in terms of longevity, which is sort of misleading. As a culture, we should be valorizing individuals that had a high quality of life right up until the end, in my opinion.
Average life expectancy has been *decreasing* in the US; snake oil and moonshots are a distraction from the actual life-extending solutions we could implement like universal healthcare
It decreased temporary during covid. It's probably going to significantly increase due to drugs like GLP-1 analogues having anti-diabetes, anti-obesity, anti-cancer, anti-atherosclerosis, etc effects. These drugs show the path forward by using drugs to modify human biology.
The decline started with COVID: so we have to see if the decline continues or stabilizes; and obesity is the main suspect if it continues.
Your videos are superb
I commented my opinion earlier. But let me say this as well, after taking my stack for 3 years now, my blood tests keep getting better. I just had my latest test yesterday and it was perfect. No more high uric acid. Cholesterol levels down to normal. HDL and LDL normal. I take NMN, NR, Creatine, Collagen, Omega 3s, Fisetin, Quercetin, and Senolytique. Keep one thing in mind as well, Scott is a writer for left leaning publications. He writes for Wired, Mother Jones, and National Public Radio. The left are those guys who all tried to get us vaccinated. Remember that and always look up those who back a eugenics narrative. Not difficult to figure out who they are.
I am 80. Take not all You listed, but it really helps. No one gives me 80. I am still in sport (table tennis), still working part time... Taking supplements from my sixties.
@@chucklohn522 I will take things that are not true for 100
Nothing to do with 'left' or 'right' - both have become corporate shill, whether for the medical mafia or the war-mongering profiteers.
Thank you. I have been taking NMN and resveratol for a while now and feel good. So I don't get the hate
Lol, creatine can make your blood tests worse. Folks, don't follow this bro science afficianado's advice.
And to think that after all of the videos I’ve watched of yours, I only JUST saw your UW degree! Always a good day when I see another Badger doing awesome stuff. Keep it up, Scott!
Fear of aging and death equates to a sense of desperation, vulnerability. Who wants to live forever 😊. Reservetrol was around and touted for its benefits many years before Sinclair studies. But sounds like he took to the fountain of youth end. I know we can live healthier standards of life. But that is up to each individual to make better choices every day.
Did Sinclair really believe in his work or was he really trying to scam for monetary value?
Thanks for your great work ❤
resveratrol has lengthened the lifespan of over half a dozen species, iirc, including vertebrates and mammals. In vitro it turned old human cells young again. These experiments would all have to be refuted to refute resveratrol
Thanks for a great job! Like to see another side of those stories! ❤
Well thanks for covering longevity. Are you still a fan of the subject?
Thanks for exposing all these people who deceive others for profit! I'm glad I saw you on Dr. Mike's show, it was an eye-opener!
Big question, how is Harvard still associated with him?
Indeed.
11:15 Harvard gets a cut of your IP, and also your federal grant dollars.
I knew taking just a pill would stop and revert aging sounds too good to be true
Imagine the cognitive dissonance inside my brain having listened to so many Huberman podcasts and believed everything Sinclair has said. To be honest this makes me doubt your videos too. How do I know you are not the grifter? If you aren’t I have fallen before for one, so how do I know the difference now?
My company and I developed and patented the first ion propelled aircrafts with onboard power. Much later a small group at MIT claimed to have developed “the first ion propelled aircraft of any kind to lift its power supply,” and they widely published it in The Journal of Nature. They have made a lot money by continuing these incorrect claims!
There are 45 flight footage videos of the earlier, much more powerful by weight, aircrafts in flight on my YT channel and site, linked to the icon on the left, including with qualified officials present. The published patents explain clearly how they work.
Interesting. Send me an email.
Love your videos. Keep them coming and thank you so much! Down with false idols and money grab schemes!
You got it!
This was quite interesting. Keep up the good work.