How to Manage Your Vitamin A Status | Chris Masterjohn Lite #60
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- Опубликовано: 15 авг 2018
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I can't thank you enough for all content on your channel! Vitamins, MTHFR, Fatty liver... This information is priceless for all people but especially for ones from poor countries. You are saving grace for people like me!
Exactly. His info is such a blessing, I want to smack some of the people leaving ass%$#@ comments.
Its important to balancing it with vitamin d, in a study without vitamin d supplementation even 5000 iu vitamin A caused bone loss!you either need lots of sun light or vit d supplement.
Well fish oil is quite balanced in that manner.
Interesting. Do you have a link for that study?
Just wanted to thank you, Chris! This series is an excellent one.
Very informative, thank you Chris
Thank you. Best presentation on this topic I guess.
Awesome info! Thx!
Great stuff as always. BTW, i like the red on black color theme
Vitamin B3 (niacin, niacinamide) helps the conversion of carotene to vitamin A.
Which is also found in animal liver
Seriously..??
Very helpful..
Thank you for sharing..!!
regards from greece :)
@@richardfrancisburton6833
A or B3..??
Thank you..!!
Regards from greece :)
Wow, thanks for the info!
*_...Also,_*
I know I'm a year late, but do you mind sharing where you learned this from? I would really like to cite it. ( •̀ ω •́ )✧
@@c.k.7361 both
Your videos are excellent. It seems good to see videos where the volume is plenty loud enough. And your content is excellent,. IMHO. Very interesting to those of us wanting to keep our nutrient levels up.
THANK YOU
some people can't convert Beta carotene into vitamin A very efficiently
You need to add info about the BCMO1 mutations.
Excellent insights Chris, 3 x 50g lamb liver each week works for me, feel amazing getting it from real food 👍
Be wary to not over-do it, copper toxicity is not fun!
Ps: zinc will fix it.
@@Youuuuuu plenty of zinc in liver
@@bolivianbillionaire1349 plenty of copper too? you need to look at the proportion
i hear that vit d could cause vit. a deficiency unless both are taken separately (and vit. a is needed more since it, and magnesium, are used by vit. d in large amounts.). vit. a defciency could also lead to acanthosis (similar to hyperkeratosis?) according to dermatologists.
You're good on micronutrients and that's why I listen to you. You mess up on the end result of the metabolism (which causes CICOpathy) but you get everything right on nutrients. I take roughly 350% of the A RDA from butterfat.
How are you consuming that much??? Isn't that a ton of butter? Or do you have a particularly pure source, like spring grassfed butter?
Given that Vitamin A easily stores in the liver and fat/tissues, please try to evaluate the metabolism and transport aspects of Vitamin A before supplementing or adopting a higher Vitamin A diet.
It's way less disruptive to simply increase one's fiber intake alongside Zinc and protein.
The metabolic pathway for carotenoids is quite lengthy involving ALDH, AOX, and Glucuronidation. The storage and transport requires enough retinol-binding protein. Any deficiencies in this path can lead to backlogs of metabolites at that step.
Even non-pro-Vitamin A carotenoids can lead to issues (e.g. lutein, astaxanthin, etc.) as they compete for being managed and clog up the route of elimination.
I have experimented with multiple sources and amounts of vitamin A. My diet is quite high in protein, and there are multiple studies that suggest vitamin A requirement increases with increased protein. Interestingly, liver tends to cause muscle cramps and/or spasms during workouts (if my intake is moderate+). I am not sure if it is vitamin A, as liver is high in many nutrients, and cod liver oil does not seem to cause the problem. The skin improvement is noticeable. I do not measure exactly, but intake from cod liver oil and liver/dessicated is probably 10-20k, and I consume lots of dairy products as well.
Why no video on vitamin E, I feel it its the hardest to manage in diet.
Thank you . But I have a question how come I know people that never eat vitamin A rich foods and don’t have any problems with their skin or vision. Isn’t most of the symptoms you said are genetic?
Dr is ot true that take suplemments of viamn A live sintetic vitmin A can cause cancer?
Thanks Dr. Chris! Is retinyl palmitate a good form?
It's synthetic. For a natural Vitamin A supplement, you need cod liver oil that has NOT had the natural A removed and/or replaced with a synthetic form. Eggs and animal livers, especially from pastured animal sources, are also good sources of natural Vitamin A.
www.greenamerica.org/blog/how-tell-if-vitamin-natural-or-synthetic
Chris, do you have some links to some studies on the connection between zinc and reduced beta carotene to retinol conversion? Couldn't find any myself. Thanks.
Here's one: www.ncbi.nlm.nih.gov/pubmed/12742542
My recent Retinol was .57 (.30 - 1.2).
I eat 4 ounces of beef liver 1x a week. Do you think I'm in good range?
I had little blisters on the back of my arms (follicular keratosis) and like little bumps on my scalp.
Both disappeared when I bought some Vitamin A drops.
I take just one drop a day (1 drop = 500 mcg/1666 IU)
Is this small dose safe for continuous use?
I also take 15 mg of zinc a day (sometimes citrate, sometimes gluconate)
Thank you
surf n turf with butter large salad and a glass of lemon water
What is your opinion on astaxanthin supplementation? Can it pose risk for Vit A toxicity? How about Krill oil? Thank you for this video.
Astaxanthin is one of the xanthophylls, a very powerful and versatile carotenoid, which, unlike most carotenoids in the body, is not converted to vitamin A.
Astaxanthin is a much more powerful antioxidant and free radical scavenger than other fat-soluble antioxidants such as tocopherols (Vitamin E) and related carotenoids (beta carotene, lutein). Astaxanthin is more than an antioxidant: it has, among other things, an anti-inflammatory and defense-strengthening effect, combats dyspepsia, promotes endurance and muscle recovery and helps against eye strain; to name a few.
@@Freedom-eo9fg Thank you!
Can I ask, what are your thoughts about retin a cream, used topical? Some talk about dangers, others say it is perfectly safe to use as a anti aging cream...
I personally would stay away from it because it mimics some effects of vitamin A but can cause a deficiency of other effects.
If I get you right, you are saying that we should take retinol, the animal form of vitamine a. I bought a vegan retinol, I cant explain how that is possible or wether they artifically gave it the structure of animal vitamin a, but it seems to exist.
Is it safe to take 5000 IU vitamin a daily in supplement form? Will it caused toxicity over time?
Also wondering about what my health coach is suggesting - a vitamin A “reset” - which we did with Vitamin D (levels went from 15 to 68 and 104) and that worked amazingly well. Somehow I’m afraid of doing this with vitamin A, without a lab, even though my son had many of the “signs”. Help!
How do you do this reset ? I suffer from HyperVitaminosis A
Yes handsome💕
He's one of the few people that actually knows what he's talking about any actually looks healthy his skin looks healthy he's at the right weight
Do you have any thoughts on retinyl palmitate vs. retinyl acetate supplements? According to Dr. Gaby, retinyl acetate has supposedly been shown to become toxic at doses 10 times lower than fat-soluble preparations like retinyl palmitate, likely due to retinyl acetate's superior bioavailability. This does not necessarily imply retinyl acetate is 10x stronger, it just may mean the water-soluble form is handled differently in the body. Anyhow, when you say try supplementing with 10,000 IU of vitamin A, is that in retinyl palmitate form or retinyl acetate?
Also, what do you think a safe daily dose of retinyl acetate is? And does it work the same way as retinyl palmitate in the body?
Palmitate is more like what you get from food. I would not take water-soluble forms unless you have an absorption defect. 10,000 IU is generally safe.
There are also some Supplements with Vitamin A from Fish Liver Oil. Are they even better than the Palmitate form?@@chrismasterjohn
@@marvinmarvin6728 They are good.
It's unfortunate that you and the nutrient detective are on such bad terms. Bad for the community. A civilised debate would do us all good.
you've talked about beta carotene and retinol. I drink milk that appears to have vitamin A palmitate. how does palmitate differ from the two you touched on
That is just retinol bound to the fatty acid palmitate.
@@chrismasterjohn so are vitamin A palmitate supplements fine to consume? Or are they synthetic?
Eating 3.5 oz of liver goes over the UL of copper, if I eat it twice a week will I be fine?
You can switch to chicken liver, it's not that high in copper.
What about red palm oil? Sustainably farmed, of course 😉
Palm oil comes from a tree and NOT an animal. It doesn't have any REAL Vitamin A. It could have pre-vitamin A (like Beta Carotene) that your body has to convert. You need a good animal source of Vitamin A like eggs, liver or cod liver oil. Carrots, sweet potatoes etc. all have only Beta Carotene, but the FDA lets them call it Vitamin A.
I have the symptoms of Vitamin A Deficiency but took Accutane 13 years ago and have felt toxic since. I have very dry eyes, and a dry mouth, as well as brain fog, digestive issues and very low sex drive. What are your thoughts?
Accutane causes cellular vitamin A deficiency. I would get a workup for vitamin A toxicity and test supplementing 10,000 IU of retinol under a doctor's supervision.
@The Roar Within For an alternative perspective, do a google search for “Grant Genereux Vitamin A Toxicity” and download his ebooks.
if your not making enough bile it wont matter how much vit A you take as you wont digest it! look up ox bile supplements,helped me within days with digestive issues and vit A deficiency
stallion758 Did you take Accutane?
I took Accutane many years ago, and recently got tested for Vitamin A which was very low. I have had good results with 5000IU retinol per day.
I am vitamin A deficient and supplementing 10,000 IU is still leaving me with dry skin. I had severe reactions to the MMR (measles rash all over my body) and I have night blindness and zero tolerance to alcohol. I believe that through my mothers family I have an ADH polymorphism. Taking riboflavin zinc and NAD along with vitamin A greatly helped but I still have deficiency symptoms. My doctor will not help with this because he does not want to acknowledge a link between vitamin A deficiency and the MMR. Can some people safely take more then 10,000 IU a day?
I hope that you are improving. Keep in mind that Vitamin A for skin is Not a "quick fix" and may take 3 to 6 months to take effect. Keep in mind also that Vitamin A is a fat-soluble vitamin and may be better absorbed with a fatty or oily meal. Cod Liver Oil forms of Vitamin A may provide some Omega 3 Fatty Acids in addition to Vitamin A. Carlson is one brand. Consider using a Vitamin D3 supplement to balance Vitamin A. Minerals like Zinc and Selenium may enhance Vitamin A's effects on the skin and immune system. Consider supplementing with at least 100-percent of the RDA of those minerals, if you don't do so already. I am not a medical professional, so these are just my thoughts.
@@davidsarr7852 Thank you :)
Hi Chris
I have a weird reaction to vitaminA be it supp or liver/CLO. I get paresthesia in my legs. Ankles, calves and back of the knees. I have bad case of LongCovid/CFS.
I just cannot figure out why. Chronic virus? Microbiome?
just 50g of liver is enought to notice. Goes away after few days.
cant find any studies or similar experiences
Not sure, but how do you know you need more?
@@chrismasterjohn I don't. But since I don't have conventional therapies available I'm trying to find my own way.
And having paresthesias after eating a bit of liver seems suspicious and and finding the cause of this might potentially give me the key or at least a clue for what went wrong with me.
Also vitamin D helps me tremendously. And I consumed quite a lot so I thought about balancing.
If I figure something out perhaps I will come back here and share.
Glad you're replying to old videos. Cheers mate your videos help me navigate this shit
I eat 1-3 carrots every day and supplement vit D 2000-2500IU/day. for long time enough. Several days ago I have tested fat-soluble vitamins, and I have too high vitamin A level, over the normal range. Do not eat liver, never supplemented vit A. Maybe should eat less carrots lol
Some people are better at converting beta-carotene than others.
beta-carotene can not cause toxicity right? I eat a diet high in carrots and sweet potatoes (combined 750 grams a day).
Wrong. High doses of beta-carotene from supplements convert to oxidation products that cause toxicity by lowering levels of retinoic acid, the activated form of vitamin A. Just don't turn your skin orange and don't juice to get orders of magnitude over what you could eat and you should be fine.
@@chrismasterjohn is cod liver oil a good option for vit a ? Also can you tell me what will help with iron overload ? My dr said he thinks I have it , he Prescribed IP6 I’ve been reading all kinds of things and it says I can also deplete zinc and copper along with iron so I won’t take that is there anything else you can recommend for iron overload
Agree with Chris. Wrong. And, even more so if your diet is sufficient in fats which accelerate the absorption and storage of all forms.
How much vitamin D does one need to balance 25,000 IU of retinol? Is there a correct ratio?
Alsoooo so curious to know this!!
I think I've seen 10:1 with vitamin A being 10. Morley Robbins said something about this. Masterjohn also might of mentioned it in a video about the Vitamin D paradox on the Ancestory Forum channel.
I'm curious what your thoughts are on the new controversy that Vitamin A is actually a toxin.
Fear mongering bs
Exploring RV Dude that information comes from the militant vegans. Surprise???
It's at least something that needs to be minimized. There seem to be too many issues stemming from high amounts of carotenoids and their metabolic offspring, retinols. At the very least, one should try a 5-6 week challenge of a high-fiber diet with enough red meat or Zinc/protein before embarking on 3,000 mcg of Vitamin A/day (or 10,000 IU).
Vitamin A never ever helped my hyperkeratosis, only Vit D especially sunshine helps...weird. And what makes it 10x worse is fish oil
Maybe you have psoriasis.
Or something microbial in nature.
Angelique (love that name), fish oil is a PUFA that is more toxic than is good. Go to Ray Peat's site to learn more.
How can fish oil make it worse, its just omega 3. Maybe you bought a low quality one?
@@birage9885
What about cod liver oil..??
Thank you..!!
Regards from greece :)
I cant find retinol supplement? did you mean retinyl palmitate?
Yes, that is retinol.
@@chrismasterjohn Hi Chris! Thanks a lot for taking the time to respond to my questions. I am trying to avoid PUFA and do not want to consume Cod liver oil. Do you happen to know any products that provide retinol without the PUFA? Thanks again!
Is there actually any direct evidence that poor converters need to consume preformed retinol? If the most prevalent SNP impairs conversion by around 59%, doesn't that just mean those individuals would simply go from needing around 900mcg as RAE to around 1400mcg? 1400mcg as RAE seems rather doable if you just drink a cup of carrot juice for example. I'm genuinely ignorant about this, so I was just curious
Very good question. I’m curious as well.
There's no direct evidence, no. The question here isn't about what has been shown to definitely be the case, but rather what is reasonable precaution given what's known about factors that render one a poor converter and the ubiquity of retinol in all traditional diets.
Traditional diets did not include dietary supplements, and even Weston A. Price was cautious about using Cod Liver Oil: nutritionrestored.com/blog-forum/topic/cod-liver-oil-is-a-poison-and-the-research-has-always-said-so/
Vitamin B5 requires vitamin A to function properly.
What is the mechanism? Pantothenic acid is easily metabolized to CoA, isn't it?
why would you want your body working hard converting plant trash in the reall thing...
A lot of the population can't even properly convert beta carotene properly
It's like people converting fat and protein into glucose instead of just eating fruit or carbs.
@@markaguilera493 fair enough, yet the amount of glucose you burn per day is not that big.
To be fair the amount of body tissue we built everyday is probably not a lot.
Then again on a fat adapted metabolism the amount of glucose you will need in a given day is even lower.
So at any case the amount of fruit or carbs you will need to avoid having to create your sugar de novo is not high.
@@stefdiazdiaz7067 The amount of glucose you burn each day depends on your physical activity but also your bmr. Fat being a slow source of energy it is ideal to fuel low intensity activity such as sleeping, breathing, hanging around, standing, walking and glucose is ideal for high intensity activity. Our bodies make all the fat and cholesterol we need and most important all the protective hormones from glucose and fructose that upgrade thyroïd function.
@@markaguilera493 most people would do better burning more fat vis a vis glucose