Serotonin, Dopamine and your Brain
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- Опубликовано: 21 июл 2024
- Drugs, Alcohol, and Mental Disorders alter your brain and emotions in ways we don't completely understand. This week we discuss the effects of some of these substances, and the parts we do know!
So spread the word (And be sure to subscribe for more Things You Should Know)
-Team TYSK
Features the song "Wickenden Kids" by the Rare Occasions - therareoccasions.bandcamp.com/
Citations (enable annotations to view):
Caron, Marc G. "Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter." Nature 379 (1996): 15.
Fozard, John R., and Hans O. Kalkman. "5-Hydroxytryptamine (5-HT) and the initiation of migraine: new perspectives." Naunyn-Schmiedeberg's archives of pharmacology 350.3 (1994): 225-229.
Huber, Robert, et al. "Serotonin and aggressive motivation in crustaceans: altering the decision to retreat." Proceedings of the National Academy of Sciences 94.11 (1997): 5939-5942.
Jentsch, J. David, and Robert H. Roth. "The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia." Neuropsychopharmacology 20.3 (1999): 201-225.
Kalivas, Peter W. "Neurotransmitter regulation of dopamine neurons in the ventral tegmental area." Brain Research Reviews 18.1 (1993): 75-113.
Lehtinen, Ville, and Matti Joukamaa. "Epidemiology of depression: prevalence, risk factors and treatment situation." Acta Psychiatrica Scandinavica 89.s377 (1994): 7-10.
Ramikie, Teniel S., et al. "Multiple Mechanistically Distinct Modes of Endocannabinoid Mobilization at Central Amygdala Glutamatergic Synapses." Neuron 81.5 (2014): 1111-1125.
Sternbach, Harvey. "The serotonin syndrome." Am J Psychiatry 148.6 (1991): 705-713.
Holy shit now I know why I feel like crap all the time. I'm never satisfied with my work and school and always trying to find the next big life event to happen. It's an intense feeling of anxiety and depression. Its very hard to sleep and shut off my brain, and so I try heavy reading to help get me tired but its not working anymore. I realized now that the most important thing to help balance your brain chemistry is sleep, but the problem is the lack of serotoin due to the heightened level of dopamine. Serotoin is needed to produce melatoin for quality sleep. I've been supplementing melatoin for a week now and it works effectively. I do recommend limiting the dosage to 0.5 mg of melatoin at night, higher dosages can disrupt homostasis and create negative feed back limiting production of your natural production of melatoin.
Serotonin is extremely important to innate immunity, something that is missed in most discussions about serotonin.
Source?
I spent hours trying to learn about these things on the internet, and I found all the answers I was looking for in this one convenient video, thanks dude 👍🏼
I think this is one of the very rare occasions l have sat through an entire video without fast forwarding. Really well explained and very enlightening. Thanks🙂
This really is a thing everybody should know. You made a really great video, keep up the good work.
I think there are essentially two types of depression, depression for no reason, and depression for good reason. If someone is always depressed with no obvious reason as to why they should be, then it's probably a chemical problem that can be treated with medication. But if someone is always depressed for a good reason, (loneliness, loss, chronic pain, etc) then that's normal, and you can't really heal normal. The treatment in this case would be to try to improve quality of life, if possible.
Yes, chemical.. because everything is chemical imbalance... but we need to find the reason that creates chemical imbalance. Read a book recently, "It didnt start with you" Mark Wolynn... found some answers there.
This is highly inaccurate in so many ways. I have no idea why it has 35 likes.
@@CJ-uj1qb just going by what ive lived man
Kinda sounds like you're condoning depression.
@@Luiseut59 no, im just not condemning it
Your videos are very well done. Thank you for sourcing your material in a practical and appropriate manner.
Internet gives me alot of dopamine i think,im straight up addicted to it.
honest
I remember reading somewhere that Social Media highers your dopamine aswell, which makes it so addictive. But once you stop using it, you appreciate other things more.
Daan87423 fascinating
shinzantetsu
me too. its social stimulation without fear
shinzantetsu
That's how it works. In fact, video games and the internet are pretty similar to marijuana in that the point of using them recreationally is to heighten your dopamine/serotonin. Marijuana does this a lot more, though. Which is why most pot smokers only do it occasionally while internet users use the internet for hours and hours daily.
thank you very much for putting your citations in the description. I find youtube a helpful source in locating academic videos but finding accurate ones are a bit hit or miss. thank you for these videos. keep up the good work
Very well done! Your video is very chop full of information and it pretty much sums up serotonin/dopamine dichotomy very well. Very informal. A+! Keep up the good work!
Thank you for a factual, intelligent, easy to understand video on Seretonin and Dopamine!
I love your passion in explaining things, thank to that i could follow what you say with joy. Great vid!
WHAT?! no more videos! your channel looks so promising especially with than name like that (TYSK)..makes me what to tune-in on something i should know about every week. Anyways, great vid by the way
These are great man, not really sure how you don't have like 100k subs already. even though its just your third video..
such an easy video to watch to learn these complicated issues. thanks
This video deserves millions of views I love it man :) please keep it up, subed for sure
i think its important to point out that changing your diet can also effect our serotonin and especially dopamine levels.
This is an awesome video :) its a pity that there are no new videos since some years, you seem like a very talented speaker :)
Great information, thanks for posting.
Great video. I've been looking into heaps of stuff like this lately. Thank you!
quality video, nice job man. you're easy to listen to. keep up the good work.
Great way to explain the usage of drugs and how it affects our brain and mainly our emotions, which is something understood by people like ancient yogis but rarely discuss in our everyday life, I gotta say I am extremely fascinated by this topic and I have done much of my own research by taking most of this substances myself so I can speak from real experience however when it comes to the discussion of this topic is rare to find someone that can understand it and appreciate it in a non-judging way.
thank you so much! this was great! I have spent so long looking for a comprehensible explanation o!! It would be great if you could post full references that came up as subtitles (if possible?) :)
Actually learned something...bonus!
I'm currently taking Zyvox aka Linezolid and i have to worry about serotonin syndrome so thank you for making this video. But when I was younger I did alot of XTC well MDMA so....im trying to stabilize it because after ding MDMA for like 1 yr str8 i sort of lost my mentality so.... yeah thank you for making this explanation. I also have done some reading on this but you summed it up well. THANK YOU!
P.S. I also smoked weed for 9 years and I recently quit this is my second year sober... I drink on occasion but I have had MRSA for 7 years...
Great video. Now I know more about dopamine and serotonin. With this knowledge I can better manage my own dopamine and serotonin.
Loved this. I'm a nursing student and this helped me really inderstand how all my SSRI and MAOI medications work. Thanks man. Subscribing for sure. You have very interesting topics
Well ya can't understand MAOIs without an understanding of the neurotransmitter octopamine
Please don't be so sure :'( I wish that doctors could have the chance to take psychiatric medications to see how they feel, then they might understand fully.
Thanks for that really informative video. Keep up the good work
Beautifully stated. I've never heard that take on drugs before - thankyou
Extraordinary presentation. I wonder what science will discover when AI algorithms eventually analyze all of the published amino acid research studies. TY for your overview.
Great video. Great guy. Hope top hear more from him in the future :)
Thank you for the video ..i watched it couple months aggo and really it helped me a lot...its really a great job !
Very well done. I found your presentation helpful. Thank you.
Amazing video. Thank you.
Great video! This was very interesting, thanks for sharing
Looks young, but he certainly knows what he is talking, he also provides references. We need more videos like this.
You explained everything incredibly well. Thank you
Ive been thinking about the relationship between serotonin and the gut. I learned the other day that something like 90% of the serotonin produced in your body is done there. Im thinking about the "normal american diet" and how John Wayne had like 35lbs of crap in his stomach when he died. I wonder if you have clean guts and a healthy diet and bacteria how that will affect depression. When sad we all eat a lot of crap foods too that may be making depression worse by sickening our guts. Also it may be having something to do with all the "weak" and subdued population we seem to have with lowered serotonin levels.
+Good Point the neurotransmitters in our brain are created in our guts using proteins that we eat. because we eat shitty carbohydrates all day we lower our neurotransmitters production
Snopes is not reliable for information. They are terribly biased and have even been self-contradictory at times.
Ali Garrett As soon as I pull up that link I get a notification about misinformation on their webpage and the status of that article is also false 😂
this guy hit the jackpot especially if you are antisocial serotonin in drugs help people be very social. .but other thing can help as well
I'm french and I loved your video! Bravo!
great content especially in 2014
I can imagine another world where this channel continued to make videos.
I wonder what the owner is doing now!
You've a great way of explaining a complicated subject
Hi sweetie, your video is amazing!!! I really appreciate you appealing to the general masses to ensure that this is a complex neurotransmitter malfunction. You are truly gifted and so helpful to all of us. I'd love to discuss with you more about the possibility of realms in the brain heart connection.
Amazing summary. Thanks!
Great video! That guy should be on TED Talks.
these woman marker sketches fitted so well with the video very great video
wow. this helped me open my eyes. i have a new perspective of my situation now.
this explains my life problem
Excellent information!!
TWO THUMBS UP + SUBSCRIBED!
Your awesome man, Thank you!
Now that was a seriously good vid!
This is a great video!! I love learning about neurotransmitters!!! 👊
well explained
very well explained - thanks !
I really liked you delivery of this video you taught me a lot also, thank you.
Informative! You just stopped me from buying a serotonin supplement. I'm gonna try the natural food option
Great job! For your health!
Great Video man, Thank You!
Too much is too less and too less is too much to handle. I liked when you said that! Because it's true you can either have too much or too less of something so you just go crazy.
This was awesome. Thank you for this video. Curious if the brain re-balances itself once one ceases to consume cocaine, marijuana etc... I'd appreciate your insight.
Thanks.
yes it does rebalance if you work on it
It takes a very long time and lot of working - after a lot of brain abuse with drugs and trauma as you have been basically neglecting your brain. So now you need to think of your brain as a baby and care, feed and teach new things like u do to a baby
Neuroplasticity is a thing... Go to a search on it. Our brains are adapted to change...
Thank you! I really like the way you explain things - please make more videos!! :)
*Dopamine is not a reward neurotransmitter.*
We now know that it's responsible for the *anticipation* of a reward but not the reception of the reward.
Thank you for the video!
A good and informative Video. Told in Layman's terms to make people have a better understanding of Depression. I found it very informative and have a better understanding of Depression. Thanks for sharing.
Awesome video.
Well explained great video
Excellent job.
good job! Really appreciated
Awesome information
So helpful! Thank you!
Thank you for information.
Now this is an amazing video
Very good sir.
Thank you for your video! It may explain what happened in Calhoun's rat experiments, which seemed to extinguish the reward feedback in even the most active and aggressive rats.
Great explanation! Thanks
great video, nicely done
Great video great presenting!
How does it actually go away you can be in between but going back and forth to each side. How do I stop that?😢 It's hard! Sometimes I think too less and other times I think too much. When there's a test I am either done too early or done too late when I write a whole paragraph about something the next second I forget everything.... I don't think it can be fixed unless there's a more depth of study to it I've came this far now and I won't stop learning. The scary part is will I remember it all I have ADHD once someone has it trust me there is no way to fix it unless you tell me that I need to stop thinking in that way and stop putting myself down well with me what I have didn't go in the right way of the cycle instead it went backwards and like you said in the beginning 👀 you are right about saying depression is hard to fix. Try fixing it going backwards that's what I'm going through. Most of the people start out with a behavioral disorder but I started with axitety and depression so that's something to really think about. I wish it could be fixed by not having any meds in my body I want to be normal but I'm not I'm a Victoria look it up in the urban dictionary the first one is who I exactly am and it's sad... I was a totally normal kid but once I got older alot of things changed and I didn't know what was happening but as of today I just learned about myself and so I have ADHD 😭❤️ Hope things get better
Thanks for your effort!
And to the author, great super awesome video I Learned a lot of information thank you again man, I would like to see more videos of yours.
Good balanced view
how about playing video games? does that effect the seratonin and dopamine?
this video really helped me understand thank you.
great vid. very informative and easy to understand... for a difficult subject to understand! lol. thanks!
Awesome video
Take away lesson is
Get high on accomplishments !
Will do !
Nicely said.
I really liked the way you made the video, not using caricature software and doing your own drawings, and being to the point and truthful. Thank you... :)
bloody good video mate!
Thank you very much.
Very interesting video.
Very informative video!
Always be happy.
You are a good teacher sir
Wow great video.
Love love love this video so easily said
excellent explanations! thank you,
im happyy i truly learn something interesting and important
Thanks for the video. I learned a bit.
Thanks for talking
Great video! Thanks Brother 'D
Awesome video bro
Please get back on youtube, video's are informative and interesting. Thanks
i got mental illness Bipolar type 2 and social Anxiety and im taking a Serotonin supplement,Would it even me out?
Thanks for explainin this so clearly