Point mutation
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- Опубликовано: 27 мар 2015
- This DNA mutation lecture explains about types of point mutations like nonsense mutation, missense mutation, silent mutation etc.
A mutation is a everlasting exchange somewhere in a DNA sequence. DNA is the unit of heredity of all organisms, so this means that mutations can most often be handed on to offspring. Mutations do not have got to be bad. Some are worthy, whilst others are impartial or don't have any effect. There are a lot of one of a kind categories of mutations, however in this lesson we can center of attention on factor mutations, or these attributable to a metamorphosis in a single or a fewnucleotides at a single area in a DNA sequence.
A mutation that includes a single nucleotide and may consist of lack of a nucleotide, substitution of a nucleotide for another, or the insertion of an extra nucleotide.
For instance, sickle-mobile disorder is triggered with the aid of a single factor mutation (a missense mutation) within the beta-hemoglobin gene at role 6 that converts a GAG codon into GTG, which encodes the amino acid valine as a substitute than glutamic acid.
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hello! please explain to me the causes and factors of spontaneous mutation. I understand that cells no longer copy properly due to natural factors. but I would like to know what those natural factors are. How do they appear and where? because everything in life happens due to some factors. thank you very much.
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Isn't the frameshift mutation is considered a different type from the point mutation??
It's classified as a separated category in books
Yea... That's what.. I'm confused too
beautifully explained
Thank you with your Videos, presentation . Can you explain how to Change gene frequency due to mutation , non recurring mutation, recurring mutation.
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When talk genetic code and codons, please refer to RNA codes, so A,U,C,G. Cuz transcription goes 5' to 3' reading the template 3' to 5'. That means though UAG is a stop codon, TAG on one DNA template would be read as 5'CUA 3' on mRNA, which is not a stop codon. People like reading codons in 5' to 3' direction, but it's confusing if you don't know which strand is being talked about. I know you're talking about the coding strand, not the template strand. Anyway, the rest of the infos are pretty informative. Peace
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Sir in any type of mutation ..is the base changed in only one strand of DNA or in both strands ?...
For example if one strand of DNA has certain sequence and lets imagine A is replced with G in one strand ..will the other strand at same position be replaced with C ,since G pairs with C ?
Each of six populations of Drosophila in
different geographic regions had a specific
arrangement of bands in one of the large
autosomes:
a.12345678 d. 14322678
b.12263478 e. 154322678
c.16223478 f. 15432678
a. Assume that the arrangement letter a is
the original one. In what order did the
other arrangements most likely arise?
b. What type of structural aberration is
responsible for each change?
Please help.. i dont understand how to solve this problem
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Shomu Biology, thank you for a clear presentation. Change in nucleotide in a codon changes the amino acid as well as the protein.. GMO technology incorporates a foreign gene, the protein are likely to be changed? Does the change of mutation in nucleotides, be equated to GMO transformation.
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Hlo sir ,you said that CAT codes for histidine but here15:52 you wrote valine (in silent mutation)
Thanku sir good explanation
How do i memorise what codon is codes for what protein and on translation what base pair changes to what ????? Is there a way to memorise??
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I knew that in case of A always add T and in case of C always G inserted in case of mutation .is that wrong concept?
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Can u make a video on molecular mechanism of chemical mutation by mutagens
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Just a bit confused between frameshift and the insertion mutation from the point mutation..can someone please help me!
You can go watch his frameshift mutation video, but basically, in Frameshift, one nucleotide is inserted or deleted, causing the entire reading frame to shift. Instead of only changing one codon like in point mutation, all the following codons are changed.
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Only those will get it who listen carefully, and if you're even getting doubts you can google them,
Understanding the concept and then reading the question is better