Cytotoxic T cells | Immune system physiology | NCLEX-RN | Khan Academy

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  • Опубликовано: 18 фев 2010
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    How cytotoxic T cells get activated by MHC-I/antigen complexes and then proceed to kill infected cells. Created by Sal Khan.
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Комментарии • 184

  • @themexiranian
    @themexiranian 13 лет назад +3

    i just like that you are drawing things out and explaining them, rather than pointing to an unmoving ppt presentation thats been molding around for years and years

  • @scramblesk8
    @scramblesk8 10 лет назад +7

    Love your videos. great idea using different colors and breaking it down with imagines. So much easier than reading a definition. Thanks!

  • @devidrsr
    @devidrsr 11 лет назад +9

    THIS IS THE BEST WAY OF TEACHING AS MY HEART SAYS

  • @shaynabourgeois7241
    @shaynabourgeois7241 12 лет назад +22

    " I am a virus, I am a virus making maching, you better kill me!" This is great! If only my instructor made her lectures like this! Thanks for being a lifesaver!!

  • @nappingracez
    @nappingracez 7 лет назад +4

    "So the big picture is, if you want to just take 20000 feet." HAHAHAHAHAHAHAHAHAHA gotta love this guy! He always makes me day studying MCAT less shitty

  • @DisKeda
    @DisKeda 3 года назад

    What this guy does can't be done better. Unbelievable videos. The best! Thank you so much!

  • @LadyD0113
    @LadyD0113 6 лет назад

    I just learned everything I need to know in an hour....than in 5 lectures...Thank you!
    Now to answer the professors ridiculous reaching questions!

  • @zuay9016
    @zuay9016 12 лет назад +4

    so these are what i've been learning in my lectures all this while!!thank you! u make my revision more enjoyable :))

  • @jessicasingh1286
    @jessicasingh1286 9 лет назад

    you have made my life so much easier.. thank you. You are a legend!

  • @ninjanerdstudent6937
    @ninjanerdstudent6937 9 лет назад +64

    Lesson learned: Shady characters need to die.

  • @xforestberryx
    @xforestberryx 14 лет назад

    this is so brilliant! ty for the upload!

  • @cherrytehhladyy
    @cherrytehhladyy 13 лет назад +1

    i'm so slow at understanding processes like this, thank you ! it was so easy for me to connect with this .

  • @in2ennui
    @in2ennui 13 лет назад +2

    Your teaching skills are AMAZING!! Very unlike my own professor... I seriously learn better from you than from sitting in class where a teacher reads slides! Step by Step drawings and words are an enormously effective technique!

  • @PurposefulPawn
    @PurposefulPawn 11 лет назад

    dude you have the best video about the lymphocytes on youtube! thanks!

  • @jerryliao5299
    @jerryliao5299 10 лет назад

    much nice visuals, many help. so thank you

  • @JoseHernandez-zh5tu
    @JoseHernandez-zh5tu 9 лет назад

    LOVE IT! GOD BLESS YOU!

  • @lloplop
    @lloplop 14 лет назад +2

    I second the grammar video!
    I really really love these videos. they help me tremendously.

  • @theprophetez1357
    @theprophetez1357 3 года назад

    Thanks Kahn you do a great job and have a new sub here. I need a break after watching two of your videos, but I certainly look forward to coming back and learning more.
    Thanks again.

  • @Ddelke
    @Ddelke 12 лет назад +1

    Thank you so much!!!! You helped me to get ready for the exam,
    keep the good work! Greetings from Serbia!! Pozdrav iz Srbije!

  • @lamishaahmed6094
    @lamishaahmed6094 Год назад

    I have been following your videos for a while, and omg every time I am in a topic, I am so amazed by you detailing and explaining skills. Khan academy is undoubtedly doing a great job of teaching people the basics of science.

  • @dulee101
    @dulee101 12 лет назад +10

    This is absolutely amazing! you saved another medical student trying to connect the dots of the immune system! Good luck with everything, these videos are so so helpful :)

  • @Nirvana87
    @Nirvana87 12 лет назад +2

    How can someone possibly dislike this??
    Awesome teacher!

  • @qteshorty634
    @qteshorty634 14 лет назад

    sweet!!! this helped a lot for my microbiology class I wish all the teachers were like you !

  • @illumineat_nutritionist
    @illumineat_nutritionist 7 лет назад

    This guy explains stuff SO well

  • @x3baybeee
    @x3baybeee 9 лет назад +77

    i think i learn better watching these videos at 2x the speed lol

  • @n3r0z3r0
    @n3r0z3r0 9 лет назад +1

    This is better then Science Fiction!!!! Amazing! Thank you so much!

  • @Elnora4ka
    @Elnora4ka 12 лет назад

    Thank you very much for your helpful lessons! God bless you!

  • @MrPeperonio
    @MrPeperonio Год назад

    amazing video thank you so much!

  • @wendyQR
    @wendyQR 9 лет назад

    thank you so much~now I manage to understand the whole process~~

  • @CRUZifyre
    @CRUZifyre 12 лет назад

    Incredible videos on cytotoxic and helper t cells, B cells.... These helped me understand more than the college classroom! Thank you!!!

  • @MrPyrhana25
    @MrPyrhana25 13 лет назад

    Best life sciences videos on you tube. Great logic of sequence!

  • @jimsperlakis5634
    @jimsperlakis5634 Год назад

    Great audio presentation!
    Best I've watched. But,
    You should start with a page that already has the cells drawn. Then, as you describe or define, you can label that specific cell and draw the specific receptor involved.

  • @ghoshsurajit85
    @ghoshsurajit85 13 лет назад

    This is an amazing video and exactly what i wanted to know regarding the T cells. so thanks a lot for the pleasent lecture.

  • @04imran
    @04imran 11 лет назад

    was never so clear about this before... thank u osm videao to learn

  • @boonlorify
    @boonlorify 13 лет назад

    Extreamly helpful!!!! I'm in med school and he explains it better than the book and/or the professors!!!!

  • @jahu198
    @jahu198 13 лет назад

    Thank you so so so much! I didn't understand a word of what they talked about at uni and now I get it. Well, at least the basics, but that's more than I ever thought I'd understand. (Especially with a teacher with a strong accent). Thank you! You're awesome! :)

  • @xwhiterabbitx420
    @xwhiterabbitx420 12 лет назад

    excellent! thank you!

  • @TheHishamable
    @TheHishamable 10 лет назад

    thank you so much !!!!

  • @joshgilbo
    @joshgilbo 9 лет назад +1

    fantastic video, finally understand, you're a legend

  • @toriroe8401
    @toriroe8401 12 лет назад +1

    ah thankyou so much, so helpful you explain things so well! you're amazing :)

  • @alimukhtar4759
    @alimukhtar4759 Год назад

    Thank u so much for such helpful content

  • @saskiakuik99
    @saskiakuik99 8 лет назад

    really helpful! thanks :)

  • @Pangjunmin
    @Pangjunmin 13 лет назад

    i can finally understand! my group spent so many hours trying to understand what the heck was going on, this simplifies it so much that i can teach it to them now :D

  • @msthekissable
    @msthekissable 9 лет назад +1

    Thanks so much

  • @pokuneff
    @pokuneff 14 лет назад

    You are a gifted and brilliant teacher. thank you so much!!

  • @iamchill702
    @iamchill702 7 лет назад

    WOW. Great explanation. Now to time to youtube other things completely not about my final tomorrow.

  • @cherrycoke8464
    @cherrycoke8464 13 лет назад +1

    Thank you so much for these videos Sal, you made me just a little bit smarter today. And you didn't bore me in the process. Big ups for that!! :D

  • @backstreetfan2887
    @backstreetfan2887 3 года назад

    thank you so much Khan Academy

  • @lronbutters5688
    @lronbutters5688 5 лет назад

    Love the T cells!!!

  • @xenon8117
    @xenon8117 4 года назад +3

    4:58 In my immunology test tomorrow.

  • @ajiboyewilliam
    @ajiboyewilliam 11 лет назад

    You really solved my problem with mhc1 and mhc11. Thanks.

  • @mizmoe81
    @mizmoe81 13 лет назад +1

    I am SUCH a visual learner! Thank you thank you thank you!!!

  • @ghost2me
    @ghost2me 12 лет назад

    hey shady guy!!
    love these videos so much!!
    thanx a lot!! :D

  • @kareemapollo
    @kareemapollo 13 лет назад

    great job khan sahad

  • @EvelynNLB
    @EvelynNLB 12 лет назад

    your the best!!

  • @amenamahmood6402
    @amenamahmood6402 11 лет назад

    awesomeeeee...i learn alot.

  • @chadsmith7203
    @chadsmith7203 7 месяцев назад

    Entire semester of microbiology and came nowhere close to grasping it like I just did. Thank you

  • @yousifradhy2148
    @yousifradhy2148 6 лет назад +1

    عاشت ايدكم

  • @agarwalsurbhi221
    @agarwalsurbhi221 11 лет назад

    thank u so much u have made my problem in mhc1 simpler.

  • @wlsgh50
    @wlsgh50 13 лет назад

    Thanks alot ^^

  • @bl3owns3all
    @bl3owns3all 13 лет назад

    Seriously, good stuff. Now i have more hope for my finals. :)

  • @cynthiad_
    @cynthiad_ 2 года назад

    This Video helped me So So Much 💯💯🙏I love your Videos because I always learn so much!!! Thank You🤗❤

  • @AznsrAwesome
    @AznsrAwesome 12 лет назад

    10 minutes before my test and I finally understand this material

  • @trustjess
    @trustjess 14 лет назад

    You are the best thing that has ever happened to me! Maybe now I'll pas A+P II

  • @sciencenerd7639
    @sciencenerd7639 2 года назад

    Amazing

  • @alphaveteducation6782
    @alphaveteducation6782 11 лет назад

    perfect

  • @rachellouisejoyce8482
    @rachellouisejoyce8482 11 лет назад

    Thankyou so much for your video's they are amazing and really helping me revise:) Keep it up x

  • @DomedOutBullyz
    @DomedOutBullyz 12 лет назад

    Man !!!You are tha MAN!!!!

  • @YaMahaWorld
    @YaMahaWorld 12 лет назад

    Mr. Salman I wish if you were my teacher, i'm currently in basic immunity course at collage and the doc make it boring and not understandable
    I'm glad that i found your channel, you helped me a lot and made it more interesting to study :)
    Thank you so much for your efforts

  • @abdulandschool2266
    @abdulandschool2266 8 лет назад

    Shot, this is on the MCAT, I have to study good, I might need it later.

  • @Mindful2222
    @Mindful2222 10 лет назад

    amazing

  • @ronzaarraf
    @ronzaarraf 12 лет назад

    God bless u

  • @kareemapollo
    @kareemapollo 13 лет назад

    great job khan sahad
    kindly expand u r area of teaching by including medical sciences

  • @Bodyskillz2011
    @Bodyskillz2011 12 лет назад

    thank you very much man its really easy and important better than our books

  • @BloxyFliks
    @BloxyFliks Год назад

    i dream of becoming a doctor one day this helps so much and also i just saw this video

  • @akmi1717
    @akmi1717 7 лет назад

    good video.

  • @pranabnirmal5597
    @pranabnirmal5597 4 года назад +1

    After 20 years into medicine.. I start understanding immunity after watching your videos

  • @khanacademy
    @khanacademy  14 лет назад +3

    RUclips just started doing that. It should be off now.

  • @mcatpdf2248
    @mcatpdf2248 8 лет назад +5

    this is extremely helpful for MCAT

  • @bjerryy
    @bjerryy 6 лет назад

    Pro!

  • @Arilaynne
    @Arilaynne 13 лет назад

    Your vids are truly great.
    But i'd like to add that thrombocytes are also not nucleated

  • @howardxing5885
    @howardxing5885 6 лет назад

    4:54 "nuts" and sacrifice
    lol

  • @nystagmus
    @nystagmus 4 года назад

    Along with MHC IIs, Dendritic cells also have MHC I
    Same with macrophages and B cells

  • @maram5102
    @maram5102 5 лет назад

    Science legend .

  • @ShimmyMD
    @ShimmyMD 14 лет назад

    @Zturn
    RBCs don't have nuclei nor any organelles like ER or mitochondria. So they don't have an MHC I.
    But they get degraded in the spleen every ~120 days

  • @paulhetherington3854
    @paulhetherington3854 4 года назад

    Sphere--XL or KL-- for cell. SIDZPHERO= Sip this, carried drink-- cells and receptors-- nodes-- arteries-- vents-- caps. Rapido-- shaped organelles.

  • @abdullahyusuf190
    @abdullahyusuf190 8 лет назад

    This guy knows everything, he's the voice for organic chemistry and differential equations

    • @Nicole-em7iv
      @Nicole-em7iv 7 лет назад

      this is pretty basic undergrad stuff. almost everyone with a bachelor's degree knows as much..

    • @basicallydelpan8768
      @basicallydelpan8768 7 лет назад

      yes probably really simple stuff. Studying it in yr 11

  • @tombiddles
    @tombiddles 12 лет назад

    I have exams coming up, You have saved my ass!! (a grateful medical student)

  • @GoodTunesFtw
    @GoodTunesFtw 14 лет назад

    I've never seen ads on his videos.

  • @chrisjay7750
    @chrisjay7750 9 лет назад

    Im trying to find in your video a reference to APC licensing but can't :( Its where T helper cells bind to a dendritic cell via the mhc class 2 and cd4+, (as well as cd40-40L) and then allow the dendritic cell to express the processed peptides on the surface of their MHC 1, to allow the recruitment of cytotoxic cd8+ t cells?

  • @ShimmyMD
    @ShimmyMD 14 лет назад +1

    I have a question...when you say the DNA gets shuffled around...do you refer to the post transcriptional modifications of pre-mRNA (exon splicing combination's)?
    Because I don't think DNA can do that. THANKS
    Great video btw!!

  • @wonkeyleggs
    @wonkeyleggs 11 лет назад

    I totally agree, there needs to be a Khan-uni degree

  • @lsu0824
    @lsu0824 12 лет назад +1

    "YOU BETTER KILL ME!" lol I love it

  • @sameenaz2006
    @sameenaz2006 14 лет назад

    @stardanny33 He is referring to alternative splicing. Different ways to splice out introns creating different sets of mature mRNA to be translated, thus giving off different proteins. Also, it gains more variance through post-translation modification, such as different forms of sorting and glycosylation at the golgi before being presented on the surface. Hope that helps.

  • @babyshamblez
    @babyshamblez 13 лет назад

    @addycastro @addycastro B cells display both MHC 1 and MHC 2. the antigens are presented on MHC 2 because the antibodies coating the membrane of the Bcell have attached to a foreign particle. this particle is then engulfed, lysed and some of the protein debris is presented on the MHC2 on the outside of the cell so the Helper T cells can come and help produce antibodies. MHC1 complexes only have antigens presented on them when a foreign body enters the cell without being engulfed...

  • @davidizquierdogomez
    @davidizquierdogomez 6 лет назад

    no cytokines to activate CD8 T cells? just the MHC I ?

  • @rosecook7110
    @rosecook7110 2 года назад

    I love his enthusiasm on all subjects 😂 teaching is his calling

  • @sarahawsome77
    @sarahawsome77 7 лет назад

    I LOVE YOU

  • @lean84
    @lean84 13 лет назад

    @in2ennui "...sitting in class where a teacher reads slides! ..." sounds like one of my classes :p

  • @Shhambolic
    @Shhambolic 12 лет назад

    the awkward moment when you realise youre paying uni loads of fees to educate you, but the place you learn the most are free videos on the internet...