SDS PAGE : How does it works?

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  • Опубликовано: 30 янв 2025

Комментарии • 64

  • @GhaniaHime
    @GhaniaHime 4 года назад +22

    Great video, my college biochem professor is making us watch this video for lab today! I'm glad you're getting exposure and views!! Great explanation and visuals.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад +3

      Thanks man ...please share among friends and help me to reach big audience

    • @lmtrevino7
      @lmtrevino7 3 года назад +2

      @@animatedbiologywitharpan You made an SDS gel and you forgot to add SDS in your gel mix. You realized this after you loaded your protein on the gel and began running it. What will your results look like? How will the protein migrate in the gel in the absence of SDS?

  • @eyalpaz6014
    @eyalpaz6014 5 лет назад +19

    Excelent video.
    But I think there is a small mistake when you talk about Glycine. Glycine pI is 6.06, so at pH=6.8 it will have a weak negative charge and not a positive charge. If it had a positive charge it would not run into the gel, but go the opposite way and exit from above.

    • @hollygriffiths9719
      @hollygriffiths9719 3 года назад

      Thanks for this comment, makes this video somewhat comprehendable... Cant believe I pay for a lecturer to direct me to videos like this that aren't even fully correct!!

    • @MannansElearning2021
      @MannansElearning2021 3 года назад +1

      Amino acid pKa1 pKa2 pI
      Glycine 2.34 9.60 5.97

    • @hola-lw1bi
      @hola-lw1bi 3 года назад

      @@MannansElearning2021 why does the pka carboxylic acid change per molecule?

  • @kaylanyoungman5517
    @kaylanyoungman5517 2 года назад +1

    Very well explained with lots of information; thank you sir.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @bhaswatichakraborty9245
    @bhaswatichakraborty9245 4 года назад +3

    Such an informative and amazing video. Such visuals will definitely help the learners to grasp the topics easily. Much grateful! Hope to see such amazing content in the future as well. 😍

  • @neelamanna112
    @neelamanna112 2 года назад +1

    Amazing..thanks a lot for wonderful animation😊😊

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад

      In order to make high quality content consistently, we need support from you. Please support us by using super thanks option. Super thanks icon is present below the video ( a heart sign with $ in it ) . You can support using paytm/ phone pe/ gPay / paypal. Your small contribution means a lot for us.

  • @plsfia4363
    @plsfia4363 3 года назад +1

    May I ask why the ionic strength necessary in the conduct of SDS-PAGE?

  • @moviemania9726
    @moviemania9726 4 года назад +1

    Great explanation

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @n-sh2014
    @n-sh2014 3 года назад +1

    Fabulous! Thanks a million.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @sristi_2360
    @sristi_2360 3 года назад +2

    Could you please say that how can we experimentally analyse whether a single band represents a single protein or two different proteins with same molecular weight.?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Spend only 4 minutes to get this answer ruclips.net/video/FHvblg338Gg/видео.html

    • @sristi_2360
      @sristi_2360 3 года назад

      @@animatedbiologywitharpan hey thank you so much. Btw, apart from 2D , can we use western blotting rather with the help of antibodies specific to my desired protein?

  • @sreeram6416
    @sreeram6416 Год назад +1

    Why specifically 5% is used in stacking gel

  • @fabianamorales2410
    @fabianamorales2410 3 года назад +1

    what are the applications of this technique?

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад +1

      It can separate proteins based on molecular weight. It's the first step to perform a western blot.

  • @cardiacmyxoma4073
    @cardiacmyxoma4073 3 года назад +1

    Thank you so much!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @khaledalharmoudi3350
    @khaledalharmoudi3350 4 года назад +1

    Thank you. it helped a lot.

  • @yumabaker9850
    @yumabaker9850 4 года назад +1

    Amazing! thank you.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  4 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @raymondshine4774
    @raymondshine4774 2 года назад +1

    It would have been better if you had put the references on each slides.
    That could be easier for us to find more infos

  • @nikitampmaurya
    @nikitampmaurya 3 года назад +1

    Thank you!

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад +1

      Please share my channel link with your friends and help me to reach big audience

    • @nikitampmaurya
      @nikitampmaurya 3 года назад +1

      Our professor introduced us to your Channel. 😊

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      @@nikitampmaurya wow ...so nice to hear that....please share with your friends and help me to reach out big audience.

  • @rahulmohanty4008
    @rahulmohanty4008 4 года назад +1

    Loved it

  • @jinx2873
    @jinx2873 3 года назад +1

    thank you

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Please share my channel link with your friends and help me to reach big audience...love from India

  • @ThiNKBiologyThiNKVISION
    @ThiNKBiologyThiNKVISION 4 года назад

    ⭐Amazing Video Sir!
    If u don't mind, Can I translate this video to my native language to explain ?
    with respective credits to You.
    Thank You sir!

  • @峰-t1b
    @峰-t1b 4 года назад +1

    Why the protein becomes free?

  • @akanshasharma1643
    @akanshasharma1643 5 лет назад

    Toooo goooodddd😘

  • @renupandey5597
    @renupandey5597 3 года назад +1

    Lovely

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  3 года назад

      Please share my channel link with your friends and help me to reach big audience

  • @PritomAhad
    @PritomAhad 4 года назад +1

    R u bangladeshi?

  • @supritadas1761
    @supritadas1761 5 лет назад

    too good

  • @AbeyPyrro
    @AbeyPyrro 2 года назад +1

    You took 1 minute 16 seconds extra.

    • @animatedbiologywitharpan
      @animatedbiologywitharpan  2 года назад +1

      Sorry about that, i hope that the content was useful

    • @AbeyPyrro
      @AbeyPyrro 2 года назад

      @@animatedbiologywitharpan was joking very well explained