Feedback Inhibition | Class 11 | Enzymes | New Syllabus | Federal Board

Feedback inhibition is a cellular control mechanism that regulates metabolic pathways by preventing excessive product accumulation. It's like a brake system that prevents the cell from overproducing certain molecules.
Here's how it works: when a product accumulates, it binds to an allosteric site on an enzyme, changing its shape and inhibiting its activity. This reduces the production of the product, maintaining homeostasis and preventing excessive accumulation.
Think of it like a thermostat: when the temperature rises, the thermostat turns off the heater to maintain a stable temperature. Similarly, feedback inhibition turns off the enzyme when the product level rises, maintaining a stable metabolic balance.
Feedback inhibition is crucial in various metabolic pathways, such as glycolysis, the citric acid cycle, and amino acid synthesis. It prevents metabolic disorders, regulates energy production, and maintains cellular homeostasis.
In summary, feedback inhibition is a vital cellular control mechanism that prevents excessive product accumulation, maintains homeostasis, and regulates metabolic pathways. It's an essential process that keeps our cells running smoothly!
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