You are just Amazing teacher .💐 your videos help us a lot. Because of your lecture we able to understand all concept very easily and properly . Please Make more video so we able to understand all concept... Thanks a lot sir ( mine favorite teacher ) 💐☺ Love from India ...😊💐
Thanks alot for helping me with some important points in metabolism. One question i wud like to raise here is why the reactions shown here show reversible arrows when the oxidative pathway is supposed to be irreversible? I see the same thing in some other videos also.
I love your videos, as a medical student they help me so much! Anyways, I wanted to ask whether the arrows shouldn't be only one sided. Isn't the oxidative phase known for it's irreversible reactions?
This is a very great video.But I am a little bit confused because in the textbooks it was said that OXIDATIVE pathway is irreversible .Can you please explain me.Thank you .
Glucose 6 phosphate dehydrogenase is a rate limiting step, it is also an irreversible step. It is inhibited by its own formation of product. High levels of NADPH will inhibit glucose 6 phosphate dehydrogenase. Glucose 6 phosphate has a high affinity for NADP+. There are deficiencies linked to G6PDH. It is the most common enzymopathy known to man. It causes hemolytic anemia and Flavism. It is treated with antimalaria medication called primaquian. That's all I know of this enzyme. -i am a podiatry medical student.
Thanks for sharing your thought. It's an irreversible step but it was written on the board (in the video) as a double arrow . By the way, G6PD deficiency patients are usually a symptomatic and they shows up their hemolytic anaemia when exposed to drugs such as anti malarial , antibiotics and much others . And so Primaquine would make a G6PD patient more prone to hemolysis . I am a medical student in my preclinical years. Thanks for your advice.
its different in textbook....but ur way of explanation is fantastic..... its as equivalent as a pre school teacher would strengthen the basics of the kids....:)
Thxxxxxxx 1) My question is why in PPP the oxidation is achieved by dehydrogenation usingNADP+ not NAD+ (as the hydrogen acceptor)?? 2) And could you please simplify the difference between NADPH & NADH for me?
Very nice lecture. But i think there is a problem with the formulas for glucose-6-phosphate and 6-phosphoglucono-D-lactone which are missing a few hydrogen.
Great video but I believe the reactions in this phase of the pathway are irreversible (one arrow). Also, I am learning in class the the last step you have here occurs in the second phase because it is reversible. Not sure if anyone knows what the right answer truly is.
Iam medical Iraqi student ,your style in teaching is fantastic and your lectures very clear thanks alot !
its almost 2019 and this vid is saving my grade, thank u for these amazing informative well made lectures :)
thank you, you helped me ALOT more than my professor would ever do.
Thank you so much for making these lectures! They are extremely helpful and very clearly explained!
I need this, it help me a lot .
Thank you Sir🙂
From-India🇮🇳
Thank you so much, you really enhance our understanding ability.You acts just like a catalyst!
You are just Amazing teacher .💐 your videos help us a lot. Because of your lecture we able to understand all concept very easily and properly . Please Make more video so we able to understand all concept...
Thanks a lot sir ( mine favorite teacher ) 💐☺
Love from India ...😊💐
You are an absolute legend!!! Thank you for all your hard work!!!
I just love to study biochemistry because of your lectures
Aren't all the reactions of the oxidative phase non-reversible?
Life saver! Love your videos so much for exam help.
Thanks alot for helping me with some important points in metabolism. One question i wud like to raise here is why the reactions shown here show reversible arrows when the oxidative pathway is supposed to be irreversible? I see the same thing in some other videos also.
You made a mistake. The oxidative phase of the hexose monophosphate pathway is an irreversible reaction.
You're saving me for exams
Thank you so much! it's really helpful :)
Yes
Deep explanation...Found it helpful thank you 👍
Thanks alot! Your videos always help me.
I love your videos, as a medical student they help me so much!
Anyways, I wanted to ask whether the arrows shouldn't be only one sided. Isn't the oxidative phase known for it's irreversible reactions?
This is a very great video.But I am a little bit confused because in the textbooks it was said that OXIDATIVE pathway is irreversible .Can you please explain me.Thank you .
Glucose 6 phosphate dehydrogenase is a rate limiting step, it is also an irreversible step. It is inhibited by its own formation of product. High levels of NADPH will inhibit glucose 6 phosphate dehydrogenase. Glucose 6 phosphate has a high affinity for NADP+. There are deficiencies linked to G6PDH. It is the most common enzymopathy known to man. It causes hemolytic anemia and Flavism. It is treated with antimalaria medication called primaquian. That's all I know of this enzyme.
-i am a podiatry medical student.
Thanks for sharing your thought.
It's an irreversible step but it was written on the board (in the video) as a double arrow .
By the way, G6PD deficiency patients are usually a symptomatic and they shows up their hemolytic anaemia when exposed to drugs such as anti malarial , antibiotics and much others .
And so Primaquine would make a G6PD patient more prone to hemolysis .
I am a medical student in my preclinical years.
Thanks for your advice.
you are the best💓thank you very much you really helped me😍😍😍
its different in textbook....but ur way of explanation is fantastic..... its as equivalent as a pre school teacher would strengthen the basics of the kids....:)
Very effective lectures .
glucose 6 phosphate where the c5 carbon one H atom is vanish
Very nice explaination....
Thxxxxxxx
1) My question is why in PPP the oxidation is achieved by dehydrogenation usingNADP+ not NAD+ (as the hydrogen acceptor)??
2) And could you please simplify the difference between NADPH & NADH for me?
Do someone know if he teach on some other platform or RUclips channel now ?
May Allah bless you :) thankyou so much.
Very nice lecture. But i think there is a problem with the formulas for glucose-6-phosphate and 6-phosphoglucono-D-lactone which are missing a few hydrogen.
Perfect❤
mind blown! thank you so much!!!!
Great video but I believe the reactions in this phase of the pathway are irreversible (one arrow). Also, I am learning in class the the last step you have here occurs in the second phase because it is reversible. Not sure if anyone knows what the right answer truly is.
yes , indeed .
Love this video.sir, 1st, 2nd & 3rd step reactions are may be irreversible reaction.
wow...............thank you Sir
Thank you sir
excellent
can u come to iraq??😅😅😂😂 we need u here
The oxygen-carbon bond broken in the second step should be the one connecting the 5th carbon not the 1st carbon though…
life saver
Thank you
I like this lecture, but is stage one irreversible
stage?
i think i'm in love
Great video! Just something I noticed was that you said a hydride ion is an H+ ion but it is an H- ion.
thanks
oxidative phase us irreversible.......cuz CO2 gas production...
isnot it like that?
Lob from Pakistan
Have an exam in a week, wish me luck!!
❤❤❤
Hallo sir g 🌹🌹🙏🙏
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Thanks