As an exercise physiologist it sounds to me like he is simply not eating enough calories and/or enough calories from fat and protein. Lose the body fat, make sure the liver is not under toxic load, and stay away from xenoestrogens as much as possible. Also, just because his blood estradiol levels are low means nothing since his SHBG is high it's binding up the estradiol which shows low or normal on blood tests. Infrared sauna helps to reduce toxic load in the liver and increases glutathione status in the process. Aveena Sativa can also be used to help lower SHBG within optimal range and DIM, fiber, and other estrogen binders can be added as well. When the body senses low or optimal estrogen levels, it will in turn decrease SHBG and increase free testosterone considering liver is okay and conversion of testosterone is satisfactory by the body not driving up estrogen and DHT which in turn would increase SHBG as well. Keep in mind that too low SHBG is worse than too high! Either way your body will regulate SHBG based on hormonal needs or what it's trying to protect you from. For example, if you are starving yourself this will decrease insulin and your body will conserve energy by increasing SHBG and reducing TSH and free T3 and other hormones that control the metabolic rate. Most docs prescribe TRT which drives down the SHBG, but this is not good if there is an underlying problem it can have severe health consequences long term. A lot to this....
I was taking DIM but stopped because I read it lowers DHT as well as estrogen and DHT is a potent androgen that helps men feel like men. My SHBG was 55 on a recent lab test with a total T of 668. I'm in a similar predicament to the gentleman mentioned in the video.
I found this true also. I had been on a low-carb diet (not keto) for years and apparently it raised my SHBG. I had to start eating more carbs to help adjust it.
This individual would be best advised to address the mycotoxin route, specifically via a doctor trained in the Shoemaker protocol capable of prescribing bile acid sqeuestrants, competent in NeuroQuant imaging and willing to pursue up to the point of treating secondary MARCONs infection and using VIP nasal spray. Not a cheap route but guaranteed to lead to better answers than the guesswork employed by your average medical practitioner. Andrew Heyman's lectures on youtube explaining CIRS to a Functional Medicine audience via the Wholistic Matters channel is pure gold on this subject and a good place to start for anyone in this person's shoes.
I have started to intermittent fast 16/8 for the past 6 most, first I noticed less energy after 1 month, I felt I was not getting enough calories. I lost 25lbs in 4 most. and I noticed that my stomach fat would not go away which was unusal for me because when I loos weight I loos it there first. I could feel that I did not have as much testosterone so I had it checked. Total was 698, free was below range and my SHGB was above range at around 70-80. I quit intermittently fasting and eat 3-4 times a day.I feel better, haven't checked any blood yet
The mycotoxin idea is legit. It was for me at least. SHBG has been coming down from 100 to 50 as I’ve improved toxic load. Eating more fatty meat has seemed to help too.
Ok so I’m a 47?year old male , started anabolics early in my teens (17) .. was doing them on and off till my mid 25s . Got married stopped for a while then in was 30 went back on again and continued till 40. No crazy doses but I’ve done all types . Stayed on a try dose till 45 then got tired on pinning so went cold turkey. Now I’m 47 . Still love to train but overtrain super easy now , cortisol is high , total T is normal 650 ,estradiol is ok at 25 , fsh is 8.3 and LH is 5.2 tsh is 2.5 so all are normal . But problem is I can’t gain any muscle mass and only seem to gain fat stomach fat ( yet I’m not reallly fat I’m 179 @ 12% bf but I’m trying to get bigger without juicing again ! My shbg is high 87 , estrone is med at 38 , progesterone is high at .8 , free T is really low at 5.9 , cholesterol is high at 222 yet I eat pretty clean and albumin is at 5.0 … Contacted old trt doc and said he want me back on T injections and add Danzol but this doesn’t adress the issue . Please help me try to narrow down what’s really going on . Lots of trt docs don’t wanna fix the issue just add drugs to mask the problem 🙏🏻 Any help I would appreciate it , if u have a direct email I can send u my labs .
Anabolics will lower shbg....... oxandralone is a good example. Furthermore, exogenous testosterone lowers shbg........ Whereas estrogens, particularly estradiol raise it. Insulin resistance lowers it as well, likely as a compensatory mechanism to free up androgens to ultimately burn fat/visceral fat and lower insulin resistance. Shbg by the way has a higher affinity for androgens than estrogens. Albumin and even igf binding protein(s!), and arguably Thyroid binding protein (in the setting of progesterone receptors on the thyroid) can also play into free hormone levels. Outside of zebra genetics, insulin resistance and heavy synthetic estrogen use (birth control), we likely shouldn't be focussing on manipulation of shbg and more on hypoandrogenic symptoms in general.... Lastly, and interestingly, I find the paradox of testosterone lowering shbg yet at the same time increasing insulin sensitivity interesting.... As opposed to low shbg FROM insulin resistance (as stated above perhaps compensatory). Perhaps in time we will see the latter point a correlation rather than causation. There are several things like this that as far as I know aren't well understood.... Another is why esterified injectable testosterones will lower HDL (both IM and SC route)and topical agents dont, although another rabbit hole to go down in that context is dht effect on hepatocytes and glucoronidation rates of metabolites to be renally cleared
When i went through a very high whole foods fruit and veg stint (90% calories from plants) my total cholesterol dropped to 70 and I was having trouble remembering a 4 digit gym code 5 mins after it was told to me. I started adding non processed fat from all sources and whole food animal protein and my memory came back almost instantly. Apart from probably being way too low on fat and protein and doing a micro nutrient assessment.... Zinc intake and my zinc to copper ratio seemed to come up as a factor!
Easy fix, DEADLIFTS! If back not good do squats 3 times a week or deep lunges 👍🏿 Medium weight squats or Deadlifts work just as well as heavy. As long as u increase the sets from 3 to 4 sets. Next take every other day a combination of boron, Vitamin d, magnesium, flax seed, black seed and Norwegian Cod Liver Oil! Watch good movies like The Northman, light cardio every other day to loose weight. And relax! Don’t over do any of this. I raised my free testosterone 23.5% after 2 years of staying the course. Also 15lbs lighter! Although my SHGB rose by 17.1% my free-tes is up😁 Good Luck 👍🏿
Great Plains Laboratory has an OAT+Mycotoxin test. Highly recommend running it. It’s expensive but it’s arguably one of the most important labs you could run.
I am very similar to the guy they mention. I have high total testosterone but my free testosterone is low. I never got SHBG checked but my albumin is high and it appears SHBG would be high. My estrogen was just a little above average. I think the problem is in the liver bc it’s producing too much protein. The liver needs to restore its function. But idk. My hormones have always been kind of fucked ever since puberty. I just want to free my testosterone damnit!
You're saying there's a correlation between high Albumin and high SHBG? I've never had my SHBG tested but my albumin was high and my free T percentage is low Cholesterol around 200
I have low SHBG and "normal" free androgens, without the low SHBG the free androgene index would not be normal (so my interpretation would be that low SHBG is same as low fT, even though fT is normal in those low SHBG cases). Plus there is often high prolactin. Something very similar to PCOS in women. In my case, free D3 is low, Selenium is low and DHEAS is high. Realy hard to interpret.
Medical science and nutritional science so complicated eastern medicine tradition medicine with its simplification in their medical systems are so appealing when I hear this stuff. Can we just live naturally?
Watched a lot of these videos and no one as of yet tells you the range. I got three blood test, dates 4/6/23 SHBG 68.9 - Range 19.3-76.4 One lab. Second lab: 4/20/23 SHBG 57.2- *Range 22-77; Third lab: 5/15/23 69.5- *Range 21.4-67.8. So the third lab shows out of range according to the range all three were out of range if I used the thrird lab range. Anyone know what the true range is?
You should use the specific lab’s range if you don’t have a data-driven reason to use a different range. There is no such thing as a “true range,” and the numbers between labs are not necessarily exactly comparable.
Ok so would this be the same for a female with same, high SHBG, normal-low testosterone, background, previously had hypothryoidism, now have normal thyroid levels.
I don’t think it makes a difference with male/female except that the sex hormone levels are generally different, but as far as I know they have the same effect on its regulation.
Go on higher fat carnivore diet, stay away from stress, heavy workouts, marathon, cold showers, fasting, drugs, alcohol, watching corn with P and other none sense....etc, and you will recover.
Some people with too high of SHGB would want to lower their level. It’s something you don’t want to be too high but also don’t want to be too low (like in your case). Just like everything else, there is an ideal level for it, and it may vary from person to person. For those with their level being too high, their free testosterone may be too low and therefore causing low testosterone like symptoms (tiredness, low sex drive, fat gaining, etc)
I also have good total Test (over 700) but low Free Test (just under or over low end of Ref range. My total Cholst varies from 160 to 190 - not low. TSH is 2.7. Getting a hormone panel done but in past SHGB was always running at high end of ref. range.
@@GroundWave Yes. Hormone panel showed high T, low free T, and high SHBG, all outside of reference range. Worst results yet. I also noticed my TSH was fairly high (3.5) but within range. After searching on PubMed I have some clues. I eat pretty much vegan with modest protein and time restrict my eating window. Avoid simple carbs. Some evidence in literature that low insulin is consistent with higher T and SHBG. Normally, men in my age group (I'm 67) have much lower T and SHBG. I eat multiple foods which contain a lot of Oleic acid (olive, EVOO, dark choc, avocadoes) which per literature shifts SHBG up. Coffee, low fat, high fiber, exercise, green tea, soy, also supposedly shift SHBG up. After cutting out olive oil avocadoes T came down to within range (700s) and SHBG drop some but still too high and free T still low out of range. So, not sure food change did this or just a fluke. Literature also noted that it's importance to have T blood draw at same time of day each time for accurate comparison, in the morning around 8 . It's what I do and also when T tends to be highest. SHBG is not supposed to be time sensitive. Blood work also showed low ferritin which might play aa role in elevated TSH, so I started taking iron bisglycinate. Need to eliminate thyroid as an issue. Will be retesting ferritin in about a month, full thyroid panel and redo male hormones making sure I'm not in an overly fasted state at blood draw. Will also keeping a food long for preceding week. The negative and positive feedback loops between the various glands in response to food etc. is pretty complex. Basically, no answers but clues and more testing and data a collection ahead.
Yes it is. You don’t want shbg too low. If it’s too low there will be higher conversion of testosterone to estrogen. And higher anxiety. From what I understand. And from my own blood work and symptoms that’s what I’ve experienced. I’m not a doctor though.
@@Dlindo8892 are you saying higher estrogen is associated with anxiety? I'm trying to figure out what went wrong on my short time on TRT. EXTREME anxiety the super energizing kind. I couldn't get Dr to test my estrogen and i couldn't afford to do it again. I just quit the testosterone
BARBELLS AND BUDS High anxiety can be coming from all sorts of factors. Low SHBG and your testosterone dose being too high. Cortisol being out of whack. Adrenal issues which is associated with cortisol. Although most of the time it’s just a matter of the dose being too high and low SHBG. The man gets a surge of hormones which in turn releases high amounts of dopamine, epinephrine and nor epinephrine and this causes high anxiety, fight or flight feeling, crawling out of your skin feeling. This goes on long enough and you start suffering with adrenal issues. The sad part is a guy goes to his primary care doctor and tells them he has anxiety they put him on anti anxiety meds, because they don’t know anything about how the endocrine system works. That’s why it’s imperative you go to someone very knowledgeable in the field. Or do your own research get blood work done.
@@Dlindo8892 my PCP prescribed me an SNRI. Let me preface by saying I have anxiety anyway just not always active. I such I didn't want to take a new medication so I didn't take that SNRI. Thank you for your feedback and I'm going to go and test my SHBG as I haven't done it yet. I did get my cortisol and northern tested and he said they were normal. I can't remember if my cortisol test was before or during my testosterone therapy though
BARBELLS AND BUDS Anytime. I also suffered from anxiety even before starting trt. Cutting out alcohol and making sure I get at least 7 hours of good sleep a night has really helped. I was also diagnosed having sleep apnea which contributed to my anxiety. So getting on a cpap has made a big difference. Good luck.
Am I the only one to point out that sex organs depend on good blood flow and that high cholesterol blocks the arteries and thus impairs sexual function? How good is it to have high free testosterone if your penile or vaginal arteries cannot be properly irrigated? I can't believe I just watched a video in which practitioners are advising someone to increase their cholesterol.
That cholesterol causes plaque remains an unproven theory. One cardiologist who has done over 5,000 heart surgeries says that he has not observed a correlation between high cholesterol and heart disease. He said blaming cholesterol is equivalent to saying that firemen cause fires because they are always at a fire. Cholesterol will be used by the body to heal damage, but does not cause the damage. In older people, studies have shown that people with the highest LDL live the longest. The CDC says that low LDL is predictive of poor Covid outcomes. This is not a settled issue by any means. We know that treatment with statins is a multi billion dollar industry and that the medical community has largely ignored insulin resistance, which many believe is the number one cause of heart disease due to the fact that it can only be corrected through diet and there is no money in that.
@Bad Example the first person who told the very truth here...SHBG and food are more connected than people think. that's why I don't buy this "prolonged fasting" BS. what for? just for free T levels dropping purposes. anyways, you're right.
@@AncestralFuel yes I am aware of that and my suggestion to lower shbg to raise free t was only for naturals and not for people on trt or people taking steroid test doses.
@@AncestralFuel everyone is n9t gonna spend years of money on some T when they can just lower SBGH to levels that arent bad but increase T for essentially free
As an exercise physiologist it sounds to me like he is simply not eating enough calories and/or enough calories from fat and protein. Lose the body fat, make sure the liver is not under toxic load, and stay away from xenoestrogens as much as possible. Also, just because his blood estradiol levels are low means nothing since his SHBG is high it's binding up the estradiol which shows low or normal on blood tests. Infrared sauna helps to reduce toxic load in the liver and increases glutathione status in the process. Aveena Sativa can also be used to help lower SHBG within optimal range and DIM, fiber, and other estrogen binders can be added as well. When the body senses low or optimal estrogen levels, it will in turn decrease SHBG and increase free testosterone considering liver is okay and conversion of testosterone is satisfactory by the body not driving up estrogen and DHT which in turn would increase SHBG as well. Keep in mind that too low SHBG is worse than too high! Either way your body will regulate SHBG based on hormonal needs or what it's trying to protect you from. For example, if you are starving yourself this will decrease insulin and your body will conserve energy by increasing SHBG and reducing TSH and free T3 and other hormones that control the metabolic rate. Most docs prescribe TRT which drives down the SHBG, but this is not good if there is an underlying problem it can have severe health consequences long term. A lot to this....
Very interesting. I have high testosterone buy I think my shgb is high. It's a 54. I'm 5'9 126 lbs. I don't eat alot and having erection issues.
awesome advice!!!!
I was taking DIM but stopped because I read it lowers DHT as well as estrogen and DHT is a potent androgen that helps men feel like men. My SHBG was 55 on a recent lab test with a total T of 668. I'm in a similar predicament to the gentleman mentioned in the video.
Glad to see that Kim Wexler was able to move on and become a successful doctor after breaking up with Saul
The fucking best comment LMAO was thinking the same thing
I got my SHBG down and free T3 up by just eating more food - no weight gain or loss.
Bad Example can you suggest a good quality boron supplement?
More protein? Veggies? Both please?
sunlight lads you need it. vitamin d , zinc , magnesium
I found this true also. I had been on a low-carb diet (not keto) for years and apparently it raised my SHBG. I had to start eating more carbs to help adjust it.
Increasing D-vitamin levels lowers significantly SHBG. The lower the vitamin D, the higher SHBG.
which vitamin d or d3?
Paul saladino said he had high levels of iron and he did blood donating which brought his levels down
This individual would be best advised to address the mycotoxin route, specifically via a doctor trained in the Shoemaker protocol capable of prescribing bile acid sqeuestrants, competent in NeuroQuant imaging and willing to pursue up to the point of treating secondary MARCONs infection and using VIP nasal spray. Not a cheap route but guaranteed to lead to better answers than the guesswork employed by your average medical practitioner. Andrew Heyman's lectures on youtube explaining CIRS to a Functional Medicine audience via the Wholistic Matters channel is pure gold on this subject and a good place to start for anyone in this person's shoes.
I have started to intermittent fast 16/8 for the past 6 most, first I noticed less energy after 1 month, I felt I was not getting enough calories. I lost 25lbs in 4 most. and I noticed that my stomach fat would not go away which was unusal for me because when I loos weight I loos it there first. I could feel that I did not have as much testosterone so I had it checked. Total was 698, free was below range and my SHGB was above range at around 70-80. I quit intermittently fasting and eat 3-4 times a day.I feel better, haven't checked any blood yet
Have you had an opportunity to get your blood work done again? It would be interesting to see if your SHBG went back down. Thanks
The mycotoxin idea is legit. It was for me at least. SHBG has been coming down from 100 to 50 as I’ve improved toxic load. Eating more fatty meat has seemed to help too.
Besides fatty meat what to do to to eliminate or reduce the microtoxin?
Mycotoxins can cause a whole host of issues that you would never think about. 100% agree. And it’s very overlooked.
@@BARBELLS-AND-BUDS Probably too late for this one, but the #1 source of mycotoxins in the US is peanut butter.
@@Murnan79 Damn not the PB lol
Hard to find any healthy clean foods anymore
@@Murnan79. I eat a lot of peanut butter. I have been chronically high for years. Thank you!
Iron overload can cause shbg to go up. EONutrition has a video about this.
Yeah just saw that and donated a pint to the red cross, fingers crossed
Dr Paul Saladino lowered his shbg by donating blood.
Yes, this works in males which got Iron overload in the blood.
This was of no help. If you dont know about it why talk about it
Ok so I’m a 47?year old male , started anabolics early in my teens (17) .. was doing them on and off till my mid 25s . Got married stopped for a while then in was 30 went back on again and continued till 40. No crazy doses but I’ve done all types . Stayed on a try dose till 45 then got tired on pinning so went cold turkey. Now I’m 47 . Still love to train but overtrain super easy now , cortisol is high , total T is normal 650 ,estradiol is ok at 25 , fsh is 8.3 and LH is 5.2 tsh is 2.5 so all are normal . But problem is I can’t gain any muscle mass and only seem to gain fat stomach fat ( yet I’m not reallly fat I’m 179 @ 12% bf but I’m trying to get bigger without juicing again ! My shbg is high 87 , estrone is med at 38 , progesterone is high at .8 , free T is really low at 5.9 , cholesterol is high at 222 yet I eat pretty clean and albumin is at 5.0 …
Contacted old trt doc and said he want me back on T injections and add Danzol but this doesn’t adress the issue . Please help me try to narrow down what’s really going on . Lots of trt docs don’t wanna fix the issue just add drugs to mask the problem 🙏🏻
Any help I would appreciate it , if u have a direct email I can send u my labs .
We have similar ranges... You gotta lower that SHBG. Totally cutting out sugar is the start.
Check out Christopher walker and his book MASTER YOUR T
Anabolics will lower shbg....... oxandralone is a good example. Furthermore, exogenous testosterone lowers shbg........ Whereas estrogens, particularly estradiol raise it. Insulin resistance lowers it as well, likely as a compensatory mechanism to free up androgens to ultimately burn fat/visceral fat and lower insulin resistance. Shbg by the way has a higher affinity for androgens than estrogens. Albumin and even igf binding protein(s!), and arguably Thyroid binding protein (in the setting of progesterone receptors on the thyroid) can also play into free hormone levels. Outside of zebra genetics, insulin resistance and heavy synthetic estrogen use (birth control), we likely shouldn't be focussing on manipulation of shbg and more on hypoandrogenic symptoms in general.... Lastly, and interestingly, I find the paradox of testosterone lowering shbg yet at the same time increasing insulin sensitivity interesting.... As opposed to low shbg FROM insulin resistance (as stated above perhaps compensatory). Perhaps in time we will see the latter point a correlation rather than causation. There are several things like this that as far as I know aren't well understood.... Another is why esterified injectable testosterones will lower HDL (both IM and SC route)and topical agents dont, although another rabbit hole to go down in that context is dht effect on hepatocytes and glucoronidation rates of metabolites to be renally cleared
Thyroid meds can increase shbg and using an androgen may lower shbg :)
Thyroid meds can lower cholesterol as well.
When i went through a very high whole foods fruit and veg stint (90% calories from plants) my total cholesterol dropped to 70 and I was having trouble remembering a 4 digit gym code 5 mins after it was told to me. I started adding non processed fat from all sources and whole food animal protein and my memory came back almost instantly. Apart from probably being way too low on fat and protein and doing a micro nutrient assessment.... Zinc intake and my zinc to copper ratio seemed to come up as a factor!
You were protein deficient, that's all. Eat your legumes
ScIeNCe
I've heard this before for older men, high SHBG is actually better for longevity.
Easy fix, DEADLIFTS!
If back not good do squats 3 times a week or deep lunges 👍🏿
Medium weight squats or Deadlifts work just as well as heavy. As long as u increase the sets from 3 to 4 sets.
Next take every other day a combination of boron, Vitamin d, magnesium, flax seed, black seed and Norwegian Cod Liver Oil!
Watch good movies like The Northman, light cardio every other day to loose weight.
And relax! Don’t over do any of this. I raised my free testosterone 23.5% after 2 years of staying the course. Also 15lbs lighter!
Although my SHGB rose by 17.1% my free-tes is up😁
Good Luck 👍🏿
Interesing about the mycotoxin raising SHGB. What is the best way to test for mycotoxin and how do you convince your doctor there is a problem?
Great Plains Laboratory has an OAT+Mycotoxin test. Highly recommend running it. It’s expensive but it’s arguably one of the most important labs you could run.
I am very similar to the guy they mention. I have high total testosterone but my free testosterone is low. I never got SHBG checked but my albumin is high and it appears SHBG would be high. My estrogen was just a little above average. I think the problem is in the liver bc it’s producing too much protein. The liver needs to restore its function. But idk. My hormones have always been kind of fucked ever since puberty. I just want to free my testosterone damnit!
You're saying there's a correlation between high Albumin and high SHBG?
I've never had my SHBG tested but my albumin was high and my free T percentage is low
Cholesterol around 200
You ever find a solution?
High albumin is good.
@@erastvandorenyo bro what did you do?
I have low SHBG and "normal" free androgens, without the low SHBG the free androgene index would not be normal (so my interpretation would be that low SHBG is same as low fT, even though fT is normal in those low SHBG cases). Plus there is often high prolactin. Something very similar to PCOS in women. In my case, free D3 is low, Selenium is low and DHEAS is high. Realy hard to interpret.
Medical science and nutritional science so complicated eastern medicine tradition medicine with its simplification in their medical systems are so appealing when I hear this stuff. Can we just live naturally?
Watched a lot of these videos and no one as of yet tells you the range. I got three blood test, dates 4/6/23 SHBG 68.9 - Range 19.3-76.4 One lab. Second lab: 4/20/23 SHBG 57.2- *Range 22-77; Third lab: 5/15/23 69.5- *Range 21.4-67.8. So the third lab shows out of range according to the range all three were out of range if I used the thrird lab range. Anyone know what the true range is?
You should use the specific lab’s range if you don’t have a data-driven reason to use a different range. There is no such thing as a “true range,” and the numbers between labs are not necessarily exactly comparable.
Ok so would this be the same for a female with same, high SHBG, normal-low testosterone, background, previously had hypothryoidism, now have normal thyroid levels.
I don’t think it makes a difference with male/female except that the sex hormone levels are generally different, but as far as I know they have the same effect on its regulation.
@@chrismasterjohn ok thank you for responding!
Go on higher fat carnivore diet, stay away from stress, heavy workouts, marathon, cold showers, fasting, drugs, alcohol, watching corn with P and other none sense....etc, and you will recover.
Hard 👎 Dr 😂
Eat fatty red meat or use beef tallow. 3 oz beef liver every other day.
Im fifteen my testosterone is 345 but shbg 62. Help/advice would be appreciated!
Also free testosterone 838 ng/dl
Not a doctor, can’t treat anyone, and can’t interpret individual cases in the comments here were there is not enough data, sorry.
The last thing you want to do is lower SHBG. My SHBG is very low at 13 nmol/L and it makes me feel absolutely terrible.
What are the symptoms of low SHBG?
Yeah, last blood draw mine was 16. It’s been as low as 12.
Too low or too high is not good...the body works best when balanced
Some people with too high of SHGB would want to lower their level. It’s something you don’t want to be too high but also don’t want to be too low (like in your case). Just like everything else, there is an ideal level for it, and it may vary from person to person. For those with their level being too high, their free testosterone may be too low and therefore causing low testosterone like symptoms (tiredness, low sex drive, fat gaining, etc)
I also have good total Test (over 700) but low Free Test (just under or over low end of Ref range. My total Cholst varies from 160 to 190 - not low. TSH is 2.7. Getting a hormone panel done but in past SHGB was always running at high end of ref. range.
Any updates? I am in the same boat as you
@@GroundWave Yes. Hormone panel showed high T, low free T, and high SHBG, all outside of reference range. Worst results yet. I also noticed my TSH was fairly high (3.5) but within range. After searching on PubMed I have some clues. I eat pretty much vegan with modest protein and time restrict my eating window. Avoid simple carbs. Some evidence in literature that low insulin is consistent with higher T and SHBG. Normally, men in my age group (I'm 67) have much lower T and SHBG. I eat multiple foods which contain a lot of Oleic acid (olive, EVOO, dark choc, avocadoes) which per literature shifts SHBG up. Coffee, low fat, high fiber, exercise, green tea, soy, also supposedly shift SHBG up. After cutting out olive oil avocadoes T came down to within range (700s) and SHBG drop some but still too high and free T still low out of range. So, not sure food change did this or just a fluke. Literature also noted that it's importance to have T blood draw at same time of day each time for accurate comparison, in the morning around 8 . It's what I do and also when T tends to be highest. SHBG is not supposed to be time sensitive. Blood work also showed low ferritin which might play aa role in elevated TSH, so I started taking iron bisglycinate. Need to eliminate thyroid as an issue. Will be retesting ferritin in about a month, full thyroid panel and redo male hormones making sure I'm not in an overly fasted state at blood draw. Will also keeping a food long for preceding week. The negative and positive feedback loops between the various glands in response to food etc. is pretty complex. Basically, no answers but clues and more testing and data a collection ahead.
DIMM helps lower it.
Isn't the latest research pointing at SHBG being important in transporting T INTO the cell? Surely too low SHBG would be as bad as too high, isn't it?
Yes it is. You don’t want shbg too low. If it’s too low there will be higher conversion of testosterone to estrogen. And higher anxiety. From what I understand. And from my own blood work and symptoms that’s what I’ve experienced. I’m not a doctor though.
@@Dlindo8892 are you saying higher estrogen is associated with anxiety?
I'm trying to figure out what went wrong on my short time on TRT.
EXTREME anxiety the super energizing kind.
I couldn't get Dr to test my estrogen and i couldn't afford to do it again.
I just quit the testosterone
BARBELLS AND BUDS High anxiety can be coming from all sorts of factors. Low SHBG and your testosterone dose being too high. Cortisol being out of whack. Adrenal issues which is associated with cortisol. Although most of the time it’s just a matter of the dose being too high and low SHBG. The man gets a surge of hormones which in turn releases high amounts of dopamine, epinephrine and nor epinephrine and this causes high anxiety, fight or flight feeling, crawling out of your skin feeling. This goes on long enough and you start suffering with adrenal issues. The sad part is a guy goes to his primary care doctor and tells them he has anxiety they put him on anti anxiety meds, because they don’t know anything about how the endocrine system works. That’s why it’s imperative you go to someone very knowledgeable in the field. Or do your own research get blood work done.
@@Dlindo8892 my PCP prescribed me an SNRI.
Let me preface by saying I have anxiety anyway just not always active.
I such I didn't want to take a new medication so I didn't take that SNRI.
Thank you for your feedback and I'm going to go and test my SHBG as I haven't done it yet.
I did get my cortisol and northern tested and he said they were normal.
I can't remember if my cortisol test was before or during my testosterone therapy though
BARBELLS AND BUDS Anytime. I also suffered from anxiety even before starting trt. Cutting out alcohol and making sure I get at least 7 hours of good sleep a night has really helped. I was also diagnosed having sleep apnea which contributed to my anxiety. So getting on a cpap has made a big difference. Good luck.
thanx cris, paleo god
High shbg have to do with low bile, too low/high cholesterol levels, no fiber, not getting adequate amounts of protein according to body weight.
Take it easy maybe stop stroking the old log
Am I the only one to point out that sex organs depend on good blood flow and that high cholesterol blocks the arteries and thus impairs sexual function? How good is it to have high free testosterone if your penile or vaginal arteries cannot be properly irrigated? I can't believe I just watched a video in which practitioners are advising someone to increase their cholesterol.
Cholesterol may be responsible for electrostatic propulsion of the RBC through tiny capillaries www.ncbi.nlm.nih.gov/pmc/articles/PMC4456713/
That's a myth. I have high collestoral and my cardiologist told me my arteries are amazingly clean. Avoid bad stress it increases cortisol.
That cholesterol causes plaque remains an unproven theory. One cardiologist who has done over 5,000 heart surgeries says that he has not observed a correlation between high cholesterol and heart disease. He said blaming cholesterol is equivalent to saying that firemen cause fires because they are always at a fire. Cholesterol will be used by the body to heal damage, but does not cause the damage. In older people, studies have shown that people with the highest LDL live the longest. The CDC says that low LDL is predictive of poor Covid outcomes. This is not a settled issue by any means. We know that treatment with statins is a multi billion dollar industry and that the medical community has largely ignored insulin resistance, which many believe is the number one cause of heart disease due to the fact that it can only be corrected through diet and there is no money in that.
Very few doctors know this
it would be more interesting how to bring it up, low shbg is one of the worst things that can happen to you and its very common on TRT
idiot
@Bad Example doing keto & IF for 2 years now, ni change in liw shbg
@Bad Example everything my friend, its genetics
Yes. This is just as important.
@Bad Example the first person who told the very truth here...SHBG and food are more connected than people think. that's why I don't buy this "prolonged fasting" BS. what for? just for free T levels dropping purposes. anyways, you're right.
Low SHBG is a biomarker of fatty liver. DO NOT lower your SHBG.
You need to lower it if you want to feel masculine as total T is almost useless if most of it is bound to shbg.
@@lewisevander SHGB transports testosterone to your organs. It's not useless.
@@lewisevander best to leave SHBG be and simply add exogenous testosterone to increase free T - but once on it, you are on it for life.
@@AncestralFuel yes I am aware of that and my suggestion to lower shbg to raise free t was only for naturals and not for people on trt or people taking steroid test doses.
@@AncestralFuel everyone is n9t gonna spend years of money on some T when they can just lower SBGH to levels that arent bad but increase T for essentially free
Iron overload!
As a female i want to high shbg pkease suggest
Increase iron
Winstrlo lower it too
Cool. Waste of time.