REGENERATIVE MEDICINE & STEM CELL THERAPIES: Their Impact On Aging [2022]
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- Опубликовано: 22 июл 2024
- I've talked a lot about stem cells and stem cell exhaustion. So today, I thought I'd do an update and talk about the latest in regenerative medicine and stem cell therapies.
But first, we'll do a quick recap and talk about what stem cells are, what exosomes are, and their role in regenerative medicine. I'll cover how stem cell exhaustion occurs. And finally, we'll take a look at a couple of clinics doing regenerative medicine and stem cell therapies in the battle to defeat that aging process.
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CHAPTERS & TIMESTAMPS:
Intro: 00:00
Stem Cells & Exosomes: 01:25
Stem Cell Exhaustion: 04:40
Stem Cell Therapies: 06:45
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I understand that some people may be desperate, but I am unconvinced on these particular treatments. As you said, there are many other things that can be done upstream.
You said that stem cells replace dead cells, and while this is true, most other cells that have not reached their Hayflick division limit (their telomeres are still long enough to divide) also divide...and perhaps we would prefer those to divide rather than wasting the resource that stem cells represent. Stem cells are your third string bench warmers...and a lot can go wrong with third stringers too. I think it makes more sense to have your telomere lengths measured, as this should give you some idea of whether this extreme and expensive measure of stem cell therapy makes any sense. If they are long, I see no reason to take that risky and expensive step. If you are 60 and have the telomeres of an 80-year-old, maybe it is worth the risks.
There are also appear to be ways to lengthen telomeres. Legumes, red peppers, dark chocolate, nuts, seaweed, spinach, fruits, berries, and 100% fruit juice, mushrooms, oats, dairy products, and coffee appear to lengthen telomeres. Smoking can be devastating to telomeres. Alcohol, red meat, or processed meat shorten telomeres. Do these things really lengthen or shorten telomeres, or do they just lengthen the lives of cells? Hard to say. There are things that truly can extend telomeres. TA-65 has been proven to. Some other supplements, make similar claims with much less proof.
I am probably going to build a hyperbaric chamber, because studies say they can extend telomeres. Though, I too likely need a test first to see if I need to extend my telomeres, and to have a baseline to compare the "after" to.
I would like to know if they extend telomeres in other cell types rather than just white blood cells. But I haven't seen anything that tested this, yet.
Telomeres, of course, are not everything when it comes to aging, but I don't think they should be ignored either.
I would be more interested to see if stem cells can do anything for scars. Seems like a little cell proliferation in concave skin scars might reduce those scars.
I can answer some of the question I read in the comments. I have been to Panama and I got 120ml Mesenchymal stem cells (MSC) IV. I found out about it from the Joe Rogan podcast. I have auto Immune issues. I scheduled my treatment and crazy as it sounds my wife ran into Mel Gibson in a restaurant the week before my flight to Panama. He was filming a movie the town over from ours. She asked about the treatment and he was very helpful. He has personally done the treatment 4 times. All I can say is if you can afford it do it. All my auto immune issues are gone. As I type this I'm a year out from my treatment. The cost was $23,500 I'm going back after the first of the year and it will be 18k this time. The clinic is awesome very professional and safe. I actually had the same Dr. as Mel. They take care of everything Transportation and the hotel. I'm 55 and I feel like I'm 35. I hope this helps someone.
Excellent videos, Lance! Subscribed.
Lance, thanks again, for yet another great contribution!
Totally agree on the "calculated risk" part, as long as your harvested cells are not planted back there is no risk of growing an extra leg or two😄 however when aging takes too much a toll, that risk could make a difference and extend your life with a couple of quality years.
I'm in my 50's so i'll stick to the NMN and Resveratrol for now but am very curious about rejuvenating stemcells and stemceltherapies.
Would you also consider Hyperbaric oxygen therapy (HBOT) to increase telomere lenght and decrease immunosenescence in isolated blood cells?
Thank you very much for Information. We look for a therapy for our Sohn with diabetes typ 1.
Thank you for sharing information
Nice one Lance. Super curious to hear how the treatment goes for you. RMI's protocol of clearing senescent cells before treatment is really interesting and seems in line with a lot of the current date about stem cell efficacy. Looking forward to hearing about your results.
Any idea why Yamanaka dedifferentiation is not used to obtain the stem cells?
Fascinating video.
Awesome info thank you!
Glad it was helpful!
Thank you for the information.
Sir if you don't mind, would you pls change the thumbnail and icon image to another one
There are two clinics- one in Panama City, Panama and the other in Medellin, Columbia -that are doing systemic stem cell therapy using screened neonatal chord mesenchymal stem cells. Mel Gibson's 90 year old dad was treated at the Panama clinic and lived another 10 years. It would be great if you did an unbiased review of those clinics
Yes, his dad got the, 'Double Dose' if I recall...or was Mel Gibson himself?
@@spyman52 I don’t know. I only know what was on the Joe Rogan show and then I did a google search on whether dad was still alive. I think he died in 2020?.
What about giostar in México? And emcell in Ukraine using fetal stem cells, saw it on a documentary called the god cells
@@james575730 not sure about those clinics but you want to steer away from embryonic stem cells. They can really go haywire and cause all sorts of weirdness
@@james575730 also fetal cell use is unethical
I’m also curious about your thoughts on the regenexx orthopedic specific procedures…
Lance:
Exceptional video!
Big question: why are clinics still using these old techniques of harvesting stem cells from bone marrow, when they can easily just create induced pluripotent stem cells (IPSCs) by introducing 3 of the 4 Yamanaka factors?
It's so much simpler to take skin cells and convert them into stem cells with the Yamanaka process.
I hope you'll explore that in a new video. Thanks in advance!
Follow-up:
Sheekey just released a video today about a paper talking about in vivo induced pluripotent stem cells!
Thanks very much!
Hello Lance
Your info is amazing. Thank you! Only found you last night. I am in the UK( N Ireland)
I am not well at all and extremely concerned for my future as to make matters worse I am completely alone. I want to remain independent but with everything I have wrong with me this will be doubtful which I find frightening
I have head to toe Plaque Psoriasis which was on my dads side of the family when I was age 4, now 57
Fibromyalgia for approx 20 yrs which I believe followed after I had Shingles
Kidney Stones approx 16yrs ago
IBS approx 20 yrs, Osteoporosis after being given Zoladex aggressive Endometriosis, Osteoarthritis on my feet
Along with all that is also regular back pain
I know that I have adhesions due to all the operations I have had
I have had a keen interest in Stem Cell Therapy for a very long time long before the average person heard about it just through doing constant research due to the extensive pain I have/still am in
I wish you knew of somewhere that was closer to me as I know there are a lot of Clinics that have set up around the world just to take peoples money so at least it is good to hear of 2 genuine places
I actually went to Mexico to have the stem cell transplant and treament done. Best decision I've ever made. My knees are improving daily. And overall health is much better. For anyone having arthritis in your joints. This is amazing.
@@monalisakhan5427 Hi there thank you so much for your reply, that is just so far away for me and to do that completely ony own frightens me and if anything did go wrong I would be well put of my depth in Mexico, May I ask how much the treatment cost if you don't mind? Did you just have to attend the once? Thank you
@@marielaw1737 the price was the main reason I decided to go to Mexico. My friend had 2 shots of stem cell from her own blood here. It was over 7k for her. Mine in Mexico for 8 shots, from my own fat and blood they took stem cell and I also get embryonic stem cell. Plus they gave my an IV infusion with 50 million stem cells.. my price was 5k. No way I could have gotten all that in the states. I'm very pleased with my choice. I wish you luck. Stem Cells are an amazing treatment. I think the doctors and scientists have just begun to explore the benefits.
@@monalisakhan5427
Hi there
Thank you for your reply
Was the treatment expensive?
Also how many times did you have to attend
At this point I feel should at least ask you the name of the clinic if you don’t mind that is?
I somehow can’t see myself travelling all that way on my own plus it would add to the cost greatly
However I really do appreciate your response
Thank you!
Is the reason you didn’t talk about the cost because of possible future affiliation? Great video as always nonetheless.
Would this help with scarring on any part of the body
Just sharing... I am patching Stem Cells Rejuvenator and Activator. (As in patch) non drugs, non trasdermal. From old, in pain and sick 54 years old to a younger, healthy and fit one.
Very interesting
any idea the cost of the therapies discussed here?
Wow thats sooo awesome that you will be doing one of these treatments!! 🤯🥳 I know you said maybe but.... heck I would too. Let us know cost too so if any of us want to do this we know if it's even within our grasp to do so. I love your channel. I always understand your explanations and it's helping me become a more educated consumer of supplements that will actually DO something for my longevity. I've been a healthnut for years but after learning more from ppl like yourself I feel more confident sharing my knowledge. It's that beautiful effect of learning and sharing just as you are doing here.
I will definitely be interested to go along!!
great video 🙏🖖
Thank you 🙌
Thx for the video. Do you believe the products like STEMREGEN. Plant based product purposes endogenous stem cell mobilization.
What about Fetal Stem Cells, have you seen the documentary by Eric Merola?
Did you ever make that GDF11 video?
hi Lance fantastic as always. please send the Costa Rica contato. thanks
Love it 🔥
Thanks 🔥
@@LanceHitchings Absolutely
What are your thoughts on the lifewave x39 patches? Supposedly they increase ghk-cu which can have a positive effect on stem cell production…
Me too, want to know your thoughts on this too
How much did RMI gene thearpy cost?
Check out the book Life Force by Tony Robbins, among others. It takes a comprehensive look at regenerative medicine.
So me a 76 year male with 22 years fighting cancer MM. Have had 3 stem cell transplantation with my own stems. A very simple procedure. Wondering if this might impact me having the procedure?
Hello Elliot
You mention you had the Stem Cell Transplants with your own Stems. Was that via a Bone Marrow procedure? I’ve heard they can be painful even with sedation?
Also where do you have this done please as I am asking this of most people
Many thanks
Anne
We are waiting for some promising successful treatment or medicine available for spinal cord complete injury as soon as possible please we wanna go for a long walk
Please specify where and which clinic performs these protocols in Costa Rica. What could be the cost?
Regenerative Medicine Institute. You'd have to contact them to get pricing. It's not cheap.
B+ for excitement to the old cranium - B- for credibility.
Any idea on why I can't get updates. Now set to none and clicking on the notification button does nothing on either laptop or phone.
Sorry, I don't really understand RUclips or how it works. I'm lucky to get my videos posted.
@@LanceHitchings can this cure blood cancer
great brother tell us about asbitence from sex benefits
Cost?
You mention a clinic by a naturopath named Harry Adelson...a non medical doctor who not only has been injecting spines of patients but also is doing procedures not authorized by the Utah Naturopathic Act. It is my very strong opinion as an actual orthopedic surgeon and regenerative medicine doctor in this field for 15+ years that Harry Adelson is in violation of the Naturopathic Act by injecting and doing procedures significantly more involved than the "minor office procedures" allowed by the statute. Harry Adelson has sued at least one other nationally respected medical specialist in this field for also voicing the opinion that Adelson is way out of bounds as a naturopath in doing these medical/surgical procedures...the lawsuit was thrown out. There are so many reputable and highly trained places to go! I appreciate your helping to protect the public from scams like amniotic stem cells, umbilical cord stem cells, and Wharton's Jelly stem cells. In addition, the public should know about all of the FDA legal actions shutting down companies like Kimera Exosomes because exosomes are not approved to be used in human AND have no human studies published in the orthopedic arena....and for sure nothing versus something far far cheaper like PRP. You have a great pulpit and hopefully people will take what you say and do their own research as well!
What places would you recommend? What do you think of the clinic in Panama
@@beezybe7166 To truly do your own best research here is what i would recommend regardless of where you are going. #1 get the names of the doctors who would actually be evaluating you and injecting your body. Make sure they are in fact doctors...google their names and see who they are and what their specialties are...see an orthopedic doctor for an orthopedic problem! Check them on linkedin. Check them on google scholar to see if they have published any research in the field. #2 Find out what sources they use for the treatment they are planning. Every study published in the USA has shown that any claims of frozen "stem cells" that are supposed to be in the amniotic fluid and wharton' jelly, and umbilical cord blood are in fact false. NONE have actual stem cells. So don't go any place trying to sell you stem cells that are not from your own body. In fact avoid them at all costs in the USA. Most international clinics use these products too....zero stem cells if not from your own body. Max profit for the clinic! #3 Be extremely wary of anyone telling you that culturing your own stem cells is worth tens of thousands of dollars more than the same day procedures we do every day here in the USA. There are essentially NO studies showing that culturing stem cells for an orthopedic injection is any better than the same day procedures we do. In fact, for many orthopedic conditions, platelet rich plasma from your own blood is more than enough and has the science to back it up!
@@beezybe7166 PRP costs in the US should range from $300- $900 per injection but all PRP is not the same which is why it is important to ask the doctor if they measure the PRP on the day they inject you....it is the only way to be sure of what you are actually getting and simply requires a hematology machine in the office. Bone marrow concentrate (stem cell) injections in the USA range from $2000- $6000 per injection and there is less evidence on when and where this makes sense compared to the more robust evidence we have for PRP use. Suffice to say that arthritic joints and degenerative tendons are two conditions for which BMC may be worth the extra cost and invasiveness. There are so many honest, thoughtful, evidence based clinicians in the USA that I can't really think of a great reason to leave the country unless it is for vacation or a condition where there is absolute proof that culturing stem cells makes a huge difference.
@@beezybe7166 IN no particular order....just off the top of my head: In Los angeles...Shounuck Patel, DO or Steve Sampson , DO In San Diego: Chris Rogers, MD, Mary Ambach, MD In Portland...Rahul Desai, MD In Dallas... me (lol) In Denver.... Chris Centeno, John Pitts, Jason Markle, Matthew Hyzy In New Jersey: Gerry Malanga, Jay Bowen IN Atlanta....Ken Mautner, MD In San Francisco....Rowan Paul, MD There are a ton more...
Urine therapy contains stem cells
What about
Macular degeneration????
Can stem cell therapy cause tumors / cancer?
if they can regenerate cells and make unhealthy cells healthy than could we presume that an IV MSC therapy be cancer preventative?
So do any of these stem cell clinics have any compelling before and after pictures or data to validate what I assume are insanely expensive treatments? Or is this all just theoretical?
Its been proposed that the benefit from stem cell therapy is from the Exosomes that the cells secret until they congest in the lungs and die. Lots of dead cells in the lung area can cause its own problem.
Doesn't seem like the science is quite there yet, there needs to be more steps to make sure the stemcell replenish the pool and not just die.
@@RobLocksley Cool. So anyway, back to my question...
@@scottk1525 It works, but the reasons and how effective it is for replenishing the Stem cells are still in question.
It is not theoretical as stem cell therapy has existed for decades.
And if you google you probably can find pictures of people looking younger, just like you look younger after plastic surgery; but that is not the main reason to do stem cell therapy, you do it to replensih your stem cells not only to look younger.
@@RobLocksley Google turns up nothing. I remain skeptical.
@@scottk1525 Me too. That is why I wrote that even if it does show youthfulness in pictures it might not be the youthfulness we want from stem cell therapy.
Works well for some cancers and such but no compelling evidence that the stem cells stay put when you inject them, even when doing so at the 'proper' places.
I remain sceptical that stem cell therapy as it is done today is usefull for stem cell population in our bodies.
brother prolong fasting also produces stem cells isnt it better then injecting stem cells
Please explain more...I want to understand
@@ifeanyijoshua6773 5 day water fast produces srem cells serch about it as the stem cells are produced your immune system will be remewed by gods will search
East Africa we use stem cells we don't depend on docs we are our own docs and we have discovered a lot. We go natural.
Hi Lance, this is Pearl from Dean's weekend. I would love to continue the professional communication if you are interested. Let me know via which platform. Thanks.
Hi Pearl. Yeah, that would be great. My email is located on my channel's "About" page. Send me an email and let's start a conversation.
Vertebrates🤔The current available therapies are just not good enough.
Agreed!
How many millions of stems we can take in a year 🙏
nobody has any scientific idea of that
If this was a viable technology with before and after results, the business would be thriving.. Here in Thailand, stem cell clinics are legal and affordable compared to anywhere else, yet their businesses are struggling. I discussed with a doctor/professor of medicine, and he informed me it was medically unproven science. I had already spent $1000 on some stem cell treatment for aging that was applied to the face, and honestly saw zero results. Remember, there’s many clinics that make extraordinary claims but have NO actual proof or scientific data to support them, which tells me they’re only looking to make a whole lot of money off people who want to look eternally young.
There are places in medicine where we have the data that stem cell therapy is useful. Within orthopedics there is a lot of data that bone marrow derived stem cells call help people with their joint pain and with tendon and ligament injuries and with back pain. There are way way more scams though and you are so right to question every claim and ask for clinical evidence that what is being proposed hs some actual basis in clinical medicine. These cash pay procedures attract the worst types of people both medical and nonmedical who simply want to separate people in need from their hard earned money.
Does anyone think it would help with dementia/alzheimers?🤔
Sounds like the powers that shouldn't be are ok with depopulation, but not with age extension. It would make for some pension challenges. Hard to pay longer on pensions when you are maintaining 100+ overseas military bases.
Here is the over-arching problem. You have over a trillion cells in your body. Trying to replace cells at a few hundred at a time seems daunting. Also stem cells have all the genetic information from your youth. You could reverse stem cells back to a more youthful state without donors (Pluripotent stem cells). Maybe it's too expensive. Anyway, the vast number of cells that would need to be changed makes this procedure seem dubious. I would want to see studies where you look at treated sites and see what the actual impact / benefit happened. Asking people how they feel is more of a placebo effect rather than a scientific effect.
I don’t know why he himself is looking old then 😂
Stem cells don't do that they are more hype than any results.
bottom line, they do not want old people to keep living and keep collecting gov't pensions and being a burden on the younger generation..........jmo
A large number of republicans want to end SS and Medicare. Scott, Rubio, Johnson and Romney are leading the charge.