Factor V Leiden - Hypercoagulability - Bleeding and Coagulation Disorders - Hematology

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  • Опубликовано: 16 июл 2024
  • Factor V Leiden is a genetic disease characterized by a mutant factor V which resists inactivation by Activated Protein C (APC). Factor V leiden is the most common inherited disease of hypercoagulability. Patients with Factor V Leiden suffer from increased risk of thrombosis especially venous thromboembolism (VTE).
    Hypofibrinogenemia and Hypoprothrombinemia...Coagulation Disorders.
    Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
    The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
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    Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
    Bleeding 🩸 time (BT) is another test for platelet function.
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Комментарии • 79

  • @mannshah518
    @mannshah518 4 года назад +27

    This channel needs more recognition. These vids are so informative but they aren't boring. Thanks for keeping our interest in medicine at a high during this pandemic. ♥

  • @sarahbradford1647
    @sarahbradford1647 3 года назад +10

    can’t believe this is the first time I’ve found your channel! the voiceover is hilarious and your teaching style is so complementary to my learning style. thank you!!

  • @mari4sol
    @mari4sol 3 года назад +2

    hi doc I just saw the video, I have Factor V Leiden - and was concerned about the corona vaccine, the subject is very complex but fantastic and easy to unterstand by you , thank you a Nurse from Germany

  • @yinkus100
    @yinkus100 3 года назад +5

    oh medicosis, always on point! I always carry my bottle of vit D everywhere because I am a classical example of the Nigerian girl who migrated to Northern Alberta!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад +1

      I wish you all the best!
      You’re such a great person!
      Thank you so much for supporting my channel!

  • @user-sw6hl1dd2x
    @user-sw6hl1dd2x 10 месяцев назад +2

    I can't prescribe my happiness that l understood this topic.. Thank u so much..

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  10 месяцев назад +1

      You're very welcome!
      Would you please help me by sharing my videos with others?

  • @roll96shreyashimukherjee32
    @roll96shreyashimukherjee32 3 года назад +3

    Highly indebted to you for all these videos. Thank you ❤

  • @BrianaKozak
    @BrianaKozak 2 года назад +2

    You made me understand something I never thought I could and it was entertaining. Love it!

  • @rigaleb
    @rigaleb 2 года назад +2

    What can you say about the novel Factor XI inhibitors, like abelacimab? Would it be more efficient than factor Xa inhibitors considering it has a considerable lower bleeding risk and apprent higher efficiency compared to enoxaparin? They say it's the holy grail of anticoagulation since it virtually eliminates the risk of excessive bleeding while at the same slowing the intrinsic coagulation pathway.

  • @manarsmaan2624
    @manarsmaan2624 2 года назад +1

    The Greatest way of teaching. Thank you

  • @laurensullivan1522
    @laurensullivan1522 3 года назад

    Brilliant! Thank you sir!

  • @malanglog138
    @malanglog138 Год назад

    wao lub you ho gya

  • @annalese6448
    @annalese6448 2 года назад

    love your vids! Hilarious and on point

  • @bahiachibi895
    @bahiachibi895 11 месяцев назад

    Thanks 😊

  • @annielawrence2985
    @annielawrence2985 4 года назад +2

    You are so fun🤩...keep doing these sir😊

  • @roll96shreyashimukherjee32
    @roll96shreyashimukherjee32 3 года назад

    Dr ,you're the best!!!!!

  • @alanothman4576
    @alanothman4576 9 месяцев назад

    you are amazing

  • @meenabarot2037
    @meenabarot2037 Год назад +1

    awesome!!

  • @jag12341976
    @jag12341976 3 года назад +1

    Philos means friend, fili means kiss!!!! Agapi is loveeeee!!!!

  • @WolfTeamDirTpride
    @WolfTeamDirTpride 4 года назад +3

    Damn, i just had Hematology exam today morning and i searched up if you have Factor V mutation but you didn't haha. I was early 1 day 🤣

  • @farihatilat7866
    @farihatilat7866 Год назад +1

    Very helpful....... Respect sir❤️❤️

  • @stvnchrist
    @stvnchrist 3 года назад +2

    There are few caucasians that were born and raised in Nigeria, but I got the point🤓”There are no solutions, just trade offs”

  • @debbieseiffertbuildingdepa4883
    @debbieseiffertbuildingdepa4883 4 года назад +1

    So I have been told I have Leiden Factor V -doubled? Found out after having my third child. I am 55 now and using cayenne and hot spices to thin my blood. I've been to hematologist here in Vegas and frankly, they didn't seem too interested in helping me, not sure why. I like to get messages especially on my legs, they always feel tight. I am wondering if it's a good idea to have massages if it loosens up the vein and can cause clots? I feel like I have very minimal circulation in my legs. I am not a student or doctor and your video is very helpful but I am still a little confused as to what to do next if there's a way to thin the blood without getting stuck on drugs for the rest of my life ( which seems to lessen the life span of peoples lives considerably I've noticed) people I know not on prescription drugs live longer than the ones on prescription drugs. An excellent video I will watch again as I am really trying to understand this, and interestingly enough I was raised to think I was 50% French and 50% German, found out I am 50% Irish/Scottish and not too much french and german as I thought (but this is from ancestry.com so who knows how accurate that is?)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +6

      Hey Debbie,
      How are you?
      I am so s you’re going through this.
      Using cayenne and hot spices to thin your blood is not scientifically proven. Moreover, it’s almost impossible to calculate the dose. In addition, you need some lab tests to tell you how bad the problem is.
      When you said: “People who are not on prescription drugs live longer”...How do you know? What hard evidence do you have? And what do you mean by “people”, or what type of “drugs”???!
      Also, I’ve never heard of Leiden Factor V- “doubled”...If I were you, I would see another hematologist....Look, it took me a long time to find the right mechanic. Finding the right hematologist is not going to be easy. Keep looking and don’t give up. I know a lot about medicine, but I will never treat myself if I had Factor V Leiden...I need a specialist who does that for a living!
      Take care!
      I wish you the best!

    • @asamanyworlds3772
      @asamanyworlds3772 2 года назад +1

      Same here

    • @opalfishsparklequasar8663
      @opalfishsparklequasar8663 Год назад

      A "double dose" of FVL
      may mean you have
      TWO copies of the gene
      (which is autosomal dominant),
      which puts you at an
      EXTREMELY higher risk
      for blood clots.
      Anticoagulant therapy is
      LIFESAVING.

  • @ThatsWhy-
    @ThatsWhy- 3 года назад

    What is meant specifically by blood stasis here in this triad, please? Is it the thrombocytosis "platelet counts"? Or velocity vs viscosity syndrome??

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      That the blood is stagnant (moving slow).

    • @ThatsWhy-
      @ThatsWhy- 3 года назад

      @@MedicosisPerfectionalis thanx dear Dr. See you soon

  • @user-gw5pb3bq8e
    @user-gw5pb3bq8e 6 месяцев назад

    Thank you very much for this wonderful explanation. I hope you enjoy this beautiful explanation 🪻❤️ Please, how can I get the pdf please?

  • @marlenescottie970
    @marlenescottie970 4 месяца назад

    Diagnosed Sept 2023

  • @mhuraic
    @mhuraic 3 года назад

    "In a place where the sun does shine" 😄 you're very funny

  • @Yousefmmohammed
    @Yousefmmohammed 4 года назад

    What application do u use to make these animated notes???

  • @VickyGoss
    @VickyGoss Месяц назад

    What if G1691 is Present ( Factor V Normal Alelle G1691

  • @DjoleeeSD
    @DjoleeeSD Год назад +1

    "only pink you are going to see is under microscope" ahahahahaha :D

  • @YT_watcher7385
    @YT_watcher7385 2 месяца назад

    I watch these videos simply to hear his annunciation of medications

  • @zakiyare885
    @zakiyare885 10 месяцев назад

    They have Thrombosis

  • @FireFly-ew9rp
    @FireFly-ew9rp 3 года назад

    Hey medicosis perfectionalist ! How many hours do u study ? Send us ur routine .I am exhausted.Need it for motivation.😂

  • @mohama2018
    @mohama2018 2 года назад

    Messi looks funny 😆

  • @amalRay23
    @amalRay23 2 года назад +1

    I FKN LUV U

  • @Full_monty
    @Full_monty 3 года назад

    What about someone who's considering trt with Factor 5

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      What about them?

    • @Full_monty
      @Full_monty 3 года назад

      @@MedicosisPerfectionalis wouldn't trt increase the chances of developing a blood clot?
      I have Factor 5

  • @slycoffy
    @slycoffy 3 года назад

    Do you have a medical speciality?

  • @asamanyworlds3772
    @asamanyworlds3772 2 года назад

    I found out I got it I had twelve blood clots

  • @LinaAlSelek
    @LinaAlSelek 3 года назад

    Too fast in your explanation

  • @BieberGirl474
    @BieberGirl474 Год назад

    Why did you shit on family doctors like that lol

  • @dr.noir27
    @dr.noir27 2 года назад

    why change the voice? what’s up with attitude!