Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation
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- Опубликовано: 26 авг 2024
- Hemophilia A - Bleeding - Most Comprehensive Explanation - Hematology, Bleeding, and Coagulation.
Hemophilia is a genetic Coagulation Disorder characterized by abnormally excessive bleeding 🩸 even after a minor scratch. Hemophilia is divided into three subtypes: hemophilia A, hemophilia B, and hemophilia C. Hemophilia A and hemophilia B are X-linked recessive, whereas hemophilia C is autosomal recessive..
Coagulation Tests (PT, aPTT, TT, Fibrinogen, Mixing Studies,..etc).
The coagulation factors are divided into 3 coagulation groups | Fibrinogen group, Prothrombin group, and Contact Group..
Platelet count is one of the lab tests used by a doctor or a hematologist to assess whether your platelet number is normal, low (thrombocytopenia) or high (thrombocytosis).
Bleeding 🩸 time (BT) is another test for platelet function.
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Medicosis Perfectionalis is another level.
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:)
He is Egyptian
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Glad you enjoy it!
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you have a good pronunciation of the arabic name, btw your videos have helped me a lot for past few months. Thanks!
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absolutely looooove this lecture, soo soo creative. you pronounce Arabic sooo good, im half arabic & cant pronounce it like u, wow!!!!
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انا فخور انك مصرى بجدددد
Thank you 😊
Dude i love u , i adore u ❤this mixing study my teacher explained it 5 times and i got nothing!!
Glad I could help!
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by any chance are you an arab? because the way you pronounced Abu al-qasim khalaf was WOAH.😌
I am!
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Yes, I am :)
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Hemophilia A treatment is PDF VIII concentrate ? ( typo error VII)?
Loved the way you roasted biology teachers.
You're an absolute legend!
Hi.. first thanks for the amazing videos... I have a comment about the treatment of hemophilia.. It is written concentrated fact 7 but you mentioned fac 8. I know fac7 concentrate is also a treatment but just wanted to say you wrote 7 if you meant 8 and if you meant both, please add 8 as well :) One general comment: you can draw a spine or a pelvic bone rather than a long bone for "bone marrow" references :) once again, thanks! love your videos
Thank you so much, Sara!
I meant factor 8, not 7
Sorry about that!
@@MedicosisPerfectionalis No worries but fact 7 concentrate is also a treatment in resistant forms, so you were technically right :)
i really liked when y talked about the first doctors in history"al zahraoui ..
This is truly one of the most comprehensive explanation ever. Bravo Medicosis perfectionalis 👏👏👏
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I LOVE how you explain stuff, always the most informative and simple presentation
Greetings from Egypt 🇪🇬
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Factor 10 is her baby😂😂😂
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اخويا فخر مصر ❤❤❤
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I loved your vidoes soo helpful in pediatrics study ❤
Are u Egyptian? The way you say abu el qasim khalaf *
Yes he mentioned it in a video
16:02 you write there f 7 but you say true :)
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What do you mean by f 7 ??
@@MedicosisPerfectionalis factor 7 writing on there
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Heterozygous females who have randomly inactivated a higher percentage of X chromosomes with the normal gene may become symptomatic, as may homozygous females
I think the answer for the question is because the patient has antibody against the Factor 8. Btw your explannation is amazing. Thank you for sharing your knowledge.
Now i knew where the name Maimonides medical center in Brooklyn came from . I was going to have my rotation in Maimonides before graduation.
Good luck 🍀
Yooo how did you pronounce the Arabic name so good dude
My guess on the question is that the girl's parents both have a defect on the genetic material. Father is very likely to be hemizigous and the mother homozigous resesive.
You got part of it!
Please see the answer in the next video!
Thank you so much 😊
شكراً 🥰
🙏🙏🙏
Thank you very much ❤
and the answer still could be von willebrant disease (type 3 ) even if it is milder than hemophilia but the common is common
the mother was a carrier and the father a sufferer ,so she got two affected X chromosomes, one from father and one from mother
Excellent!
Thank you very much for your effort
God Bless you!!!!!!!!!!!!!!
God bless you too!
Hello !!! I have some questions about hemophilia A. What do you think? Which years old the hemophilia will be disappeared.
And what do you advise for youngers and adults to grow up brave without any pains and bevel arms or legs.
Thanks for answer...
really useful! thank u
Thank you so much 😊
heyy 🖐️🖐️great doctor i ever seen 🙏 please you make mnemonic of clotting factor
That’s a good idea 💡
كفو عليك
XLD >> Hypophosphatemic rickets
Case scenario : it could be vwD tybe 3 i geuss
Loved the way u explained the whole concept, as well as ur cross talks.! Thanks a ton❤️❤️❤️.!!!
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The best videos!
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You are funny still 🤣🤣🤣🙌🏽
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I think the baby girl’s father is hemophilic and her mom is the carrier . Or her coagulation factor VIII is inhibited by antobody
Very nice thank you
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Thank u so much doc
My pleasure 😇
answer to your question is : the woman must be the carrier.Due to some causes may be the reason may be drug therapy the dominant gene gets inactivated then the recessive gene express itself and disease manifest clinically
4:22 Al Zahrawi!!!!!!
Good , I like all vediow
Thank you 🙏
thanks alot arabic guy!!!!!!!!!!
on mixing studies, i think you should say that the aPTT remains prolonged (high) not low!!
Yes
This is so much simpler than what I learn in nursing lecture 😂😂
Awesome 👏
Thank you ♥️
My pleasure!
Hi ,thanks for the mesmerising explanation!
I have a qst , why are corticosteroids given to Haemophilic patients? Aren't they supposed to block arachidonic acid pathway by blocking phospholipase A and have antiaggregant effect on platelets therefore they worsen the hemorrhage and do not improve it !? But at the same time cortisol in high doses has a procoagulant effect! This is really confusing and contradictory 😭 can u answer that qst plz and thanks in advance
I’ve never heard of giving steroids to hemophilia patients!
@@MedicosisPerfectionalis hmmm ,no it's not to treat the pathology (Haemophilia)itself, it's used to treat hemarthrosis for example ,by inhibiting inflammation, the paradoxical thing here is that corticosteroides inhibit platelets aggregation isn't it? So corticosteroides in this case are like a honey mixed with poison lol how can we explain this, sir, in your opinion?
a funny way to learn
Thank you 🙏
Hahaha woww you make it soooo lovely 🤩
Thank you 🙏
@@MedicosisPerfectionalis my pleasure
Ehy BT is normal??? If BT is normal.. then why small cut leads to a lot of bleeding. Please reply bow I have exam tomorrow.😅😭
my man minute 16:30
in the treatment section it should be factor 8 instead of seven
Yes
In treatment factor viii is used or vii? U r saying viii but in video it's vii showing
Oops 😬
Sorry 😐
Hmmm. she has inherited an inhibitor against factor V111. Don't know. BTW your graphics are amazing. But then I am an artist and not a scientist. Different side of the brain eh! Thank you for your dedication toward teaching of everyone who comes to your site.
You’re very welcome, dear :)
Thank you so much for your kind words.
Haha 😂, yeah, different side of the brain...You’re a scientist too :)
Regarding the question...I don’t think there’s a difference-genetically- between a deficiency and an Inhibitor...If it's X-linked recessive, then it’s X-linked recessive whether it’s a deficiency or an inhibitor.
Can you please try again?
@@MedicosisPerfectionalis I'll attempt it again. Her F V111c is low because she has type A, despite being female. Most people with type A are male.
@@hannahrosa5485 vWD I think.
Thanx alot dr
Thank you so much
Of course!
I appreciate it!
Impressive Arabic pronunciation
Thank you!
U r amazing 🙏
Thank you!
The first part of the video was just like i'm watching a comedy movie 🤣🤣❤
But sir i didn't really understand the idea of x-linked recessive, the carrier thing and the whole mechanism i always had problems understanding those heredity-related stuff :( would you please help me with it? Or if you have a video where you elaborated a lil bit more about heredity, please put me a link 💔 and thanks alot.
this is amazing XD
Thank you so much 😊
Is pencillin z contra indicated in this case?
🧡🙌🏼🙌🏼love ya.
Thank you so much ☺️
11:48 main lecture
It is because of von willibrand factor deficiency
What is “it” referring to?
iam back although i wasnt away
Welcome 🤗