Spravato vs. Ketamine Infusion
HTML-код
- Опубликовано: 28 май 2024
- Spravato vs. Ketamine Infusion is depression treatment comparison that Dr. Mandel shares his thoughts on. He'll review how the chemical make up of the medicine and route of administration may impact the effectiveness of the nasal spray relative to the intravenous method.
Ketamine Clinics Los Angeles is a world-renowned provider of ketamine for depression, ketamine for treatment resistant depression, and Ketamine Infusion Therapy for the treatment of suicidality, anxiety, post traumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), and chronic pain. KCLA has an 83% success rate treating patients suffering from mood disorders and a 70% success rate treating patients suffering from chronic pain.
Whether you’re seeking anxiety treatments, alternative treatment for bipolar disorder, or treatment for any of the conditions listed above, call 310-270-0625 now for a free phone consultation.
We’re the first and only Ketamine Clinic to be accredited by AAAASF! We set the gold-standard in patient comfort and safety with over 10,000 infusions provided as of November 2020. As one of the first clinics to open in the United States in early 2014, we’ve seen a lot. One thing remains constant; ketamine for treatment of depression works. Visit www.ketamineclinics.com/ to learn more. 
Наука
we need more providers like this who recommend all options even if it doesn't benefit him directly
Thank you for your kind words!!
@@KetamineClinicsLA Didn't mention TMS, though?
As a patient, I’m steadfast in meticulously researching everything I can about potential treatment options. Largely because educational information has either been unavailable, or (what is, is) delivered in some form of sparsely worded, dumbed-down marketing material. So my researching undergoing a potential spravato treatment led me here. And all I can say is “thank you”! I greatly appreciate you taking the time to go INTO the science involved, as well as the manner in which you expressed your personal opinion, without disregarding the alternative. Your patients are blessed to have you!
Thank you so much Missy! I'm glad we could be helpful. If you have any other questions RE: ketamine treatment, please don't hesitate to reach out. 310-270-0625. -Alyssa, Patient Care Manager
God love you doc. Thinking outside of the box, always looking for ways to help patients. Ketamine saved my life.
Excellent straightforward information. Thank you, Dr. Mandel.
Excellent. Do you do home visits to Australia? I have had Ketamine infusion for pain and discovered it turned something on in my mind and started turning the depression off.
We need Ketamine clinics in Australia.
Hi Ian, unfortunately we only work full time in our clinic in Los Angeles! I agree, Australia should offer the treatment. I believe there are some Dr's there who offer nasal spray or oral ketamine, but I'm not positive if they still do. If you are ever able to make it out to California feel free to keep us in mind!
Dr. Mandel, absolutley love this man. Helped me a lot during my treatment and he absolutley cares about you. Highly reccomend going to him
Amazing video, thank you! Just started spravato after weighing my options between that and IV. Mainly it was cost, but I already feel like a new person. I wouldn’t hesitate to try iv ketamine though moving forward, this works for me
You're an amazing doctor! Thank you
This is so interesting, I love this Doc's brief run down on the history/chemistry of ketamine. This dude should teach at universitys
Thank you so much! :) Please feel free to reach out if you ever have any questions 310-270-0625.
I love all the cool words he uses.
Been on Prozac for 30 years and in been in bed since June . Thank you >>>>>
This could be a great treatment option for you! Majority of our patients who seek treatment are considered treatment resistant, which means medications and other treatments have not worked well for them; we do have over an 80% success rate with treating mood disorders. We offer a free phone consultation if you are interested in learning more about Ketamine Infusion Therapy and if this may work well for you! 310-270-0625. -Alyssa, Patient Care Manager
@adam solomon Dr. Mandel is only affiliated with Ketamine Clinics Los Angeles, we have one location near Culver City. He does not work for any other location or hospital/facility. He does not do any other type of medicine at this time besides Ketamine Infusion Therapy- I confirmed this with him.
It’s expensive, it works for me IV infusions unfortunately it ware’s off over time. It’s possible to become addicted to not having thoughts of harming yourself and paralyzing depression. At 500 per treatment it’s not feasible. It’s unfortunate it’s so expensive it’s the only thing that I’ve found that works.
My psychiatrist has been talking about Spravato because I have been on every pill, and TMS was an absolute nightmare for me. I also have chronic pain from Lyme disease that is making my depression worse, and I don't feel like I have anything to lose anymore. It sounds like IVs work better, I didn't know that was an option at the Spravato clinics if the nasal spray fails. Thank you for the information. My psychiatrist can't answer questions very well, she just pushes expensive treatments, but my insurance will cover it. They know about anything is cheaper than being inpatient.
No problem at all! Please feel free to call our clinic if you have any additional questions 310-270-0625.
Yea, but the cost is wayyy different, plus Ketamine isn't covered by insurance
I'm starting Spavato very soon within days. Looking forward to it.
I am med-resitant.
Thank you so much for this video. Very helpful. Was approved for spravato but I think I’m going to spend the money on the infusions as it seems like the success rates are higher.
Wow. The fact Johnson and Johnson patented the S isomer is really interesting. I’m very fascinated with the science.
I’ll be starting ketamine infusion therapy in a few weeks. It’s free at a hospital an hour away from me.
How has it gone for you?
How was your experience with ketamine.. was it helpful..has it any side effects.. please let me know..i am struggling with depression for 2 years
Agnes of Aurora,
How was your experience?
Which state are you getting it at?
I am looking for options..
Where did you get your treatment? How are YOU doing? Successful I hope.
And where was this hospital?
Dr. Mandel did wonders for me.
Thank you for your very kind words about Dr. Mandel!
@@KetamineClinicsLABurn in hell
Except most insurance companies don’t pay for ketamine infusion. Medicare pays for spravato.
Wow! I did not know that! Thanks sommuch for sharing this info! But how do I find a clinic like yours, where they know how to adjust the dose? I live on the East Coast.
Hi Julia, ASKP.org has a directory/provider list that could be helpful. Unfortunately I am unable to give you a direct referral since I do not know exactly how every clinic runs. We do however have many patients come from out of state or even out of the country to visit for treatment, so if you are unable to find one in your area you are more than welcome to reach out to us! 310-270-0625. We have a hotel within walking distance that many out of town patients stay at. Please let me know if you have any questions. Happy Holidays! -Alyssa, Patient Care Manager
CT
My doc just gave me 20mg in each nostril I’m 150 pounds I don’t feel anything not even close to IV infusion.
So if it's only 40%, then why not simply increase the dose of spray in the nose?
does ketamine have any roles in treating obsessive compulsive disorder?
This isn't completely accurate. The Spravato prescribing information indicates that the dose can be raised by using up to 2 additional nasal spray devices to give up to a total dose of 84mg.
Realistically,it needs to be absorbed, the glands can only absorb a limited amount per minute
What about nerve pain that's not necessarily damage? As I'm not sure if glutamate is released if there's no damage. And ket works on glut to block it. If it's not released, thus, isn't the cause of the pain, ket won't do anything.
I started Spravato (via nasal injections) last week, after 2 sessions my anxiety vanished and my mood improved a lot. The experience is very enjoyable too, it makes me fly high.
By the way, do you know if Spravato is compatible with mild renal impairment ? I forgot to tell my psychatrist about that.
I wish I could find info about BP increase in Sprivato therapy. I have a volatile bp that reacts to meds. I think I will only do this if I can take 1 mg Catapress first.
The S isomer isn’t as therapeutic as the R or racemic it doesn’t act on all the neurotransmitter that ketamine dose. But also the administration makes a huge deal. Infusion your connected to drug for several hours at a time allowing the drug to actual have time to cause long time beneficial effects. Spravato you take up to twice a week and it is good for depression but it’s really not a long term solution (this coming from a Soravato patient and health professional highly knowledge in the class of drugs ketamine falls under) unfortunately infusion are so expensive. They do have racemic ketamine pills you can get prescribed or compounded for low daily nasal dosages.
Thank you for your comment! Route of administration, as you mention, is so critical in the antidepressant effect of ketamine therapy. We hope this information becomes more widely known to those who can benefit from IV Ketamine Infusion Therapy. We appreciate your support.
Yep the nasal spray worked 1-2 times then i just felt anesthetic high and my thyroid suffered
Its too low and too often and i found myself chasing the first treatment feelings which breeds addiction yo chase something not designed to help but give u just enough to keep taking it! 👎
Ketamine is very very different then Spravato so im going with the in home sublingual even though i have to pay for that ill be done in less than a month !
Thank you for this information, Doctor, but could you give us just a couple of examples of what alternative treatments there are to ketamine and Spravato for depression and anxiety? Thank you.
transcranial magnetic stimulation (TMS) is one that we are adding soon and that many patients have found to be effective. it is often covered by insurance.
@@KetamineClinicsLA how much is one treatment. Is this safe for a patient who has had breakdowns in the past, or cardiac issues. Thanks. If you cannot answer these questions, i will call your clinic
@@michelesinclair4360 Thanks for the questions. These are not easily answered in this forum. We need to better understand what you mean by "breakdowns" and "cardiac issues". Neither are a disqualifier, but with anything, we need to know details to give an appropriate assessment. Please call us and we are happy to speak with you.
Too bad I don’t have $3,000 for 4 weeks of ketamine infusion.
Hi there, we are sorry to hear this. We do offer our patients interest-free financing for one year and super bills to assist patients with filing insurance claims. If you have additional questions, please don't hesitate to contact our patient care team at (310) 270--0625. We are open Monday-Friday 9am-5pm PT. Sincerely, Team KCLA
In germany you can get ketamin prescribed.
Kaan T any first world country except the US will cover at least a part of this. In Canada you may have to pay a portion of the price for the drug, but you will not pay to get it administered!
Spravato, which is the ketamine nasal spray treatment, has been much more effective for me than the infusion treatment and my Medicare Advantage plan is covering 100% of the cost of the drug.
@@davidwainwright8714 i am the opposite! The first 6 spravato treatments were great! By the 8th one it stopped having any effect. Taking out the R molecule makes it less effective than plain K. But insurance wont cover infusions...just Spravato. I wish i could buy it some other way. Maybe infusion prices will drop
I’m going to try it because Medicare covers it. Does this clinic take insurance or is everything cash or payment plans?
Hello, we do not accept Medicare and are out of network with insurance providers. We do offer financing options for patients. Please feel free to give us a call if you have any additional questions! 310-270-0625.
So, I have a concern that I am hoping have a little light shed on before beginning treatment. I have an upcoming appointment scheduled for this Monday, that I’m really excited about.
From the research I’ve gathered thus far, I’m feeling very optimistic about giving Spravato a shot. It’s my understanding that it must be taken continuously over time, and the amount of treatments is based on a case by case treatment plan. What I’d really like to know is, how clients with long term usage, have done with Spravato. Those whole have gone into month 10, and then 1 year and beyond. Id like to know if clients are feeling an even baseline of relief over time, where they begin to finally reach a point, where they continue to remain positive that the days of having to struggle just to get through the day can finally feel like there over. I want to hear that, this can be a long term solution that keeps working over time.
Please, anyone that has information on the statistics of the average case study on this, I greatly appreciate your candor examples.
what if you can't afford either on medicare advantage? I'm near the end of my rope. Financially struggling and none of the meds are working and I've been on nearly every one
I agree, it should be available at public hospitals. The drug is cheap. It is made expensive because you need to pay an anesthetist and rent premises. That's why it is too expensive for a lot of people. The nasal spray has been made from a derivative by a pharmaceutical company and they are charging a lot for it because they have to get a return from the expensive trials they had to do. As Dr Mandel says It can be given as an intramuscular injection, which means you don't need an anesthetist to set it up. It;s not as good, but it is quite good. I've had both. A nurse can inject it. It should be available free or at low cost if people have a referral from a GP or psychiatrist. Many severely depressed people aren't able to work, so how can they pay for it?
Hi there. It sounds like you have been working very hard to manage your depressive symptoms and that is courageous. While it may seem like you've tried every treatment option available, more progressive treatments are available. We urge you to not give up hope and to please explore other options. We can discuss our treatment with you more, including financing options that are available. We also wish the treatment was more accessible and we hope that as these incredible results continue to withstand the tests of time, it becomes more accessible to all. If you are feeling suicidal, please call the National Suicide Prevention Lifeline at 1-800-273-8255. They can help.
Ketamine Clinics of Los Angeles the stuff (Ketamine) barely costs anything, help the guy out a bit, let him pay what he can.
I have Medicare Advantage too (Humana PPO) and they are paying 100% for Spravato which is the ketamine nasal spray.
@@davidwainwright8714 is the spray working for you
I would love to try ketamine infusions but in my area there is only a couple places that do it and it’s very far away. Also, I don’t know for sure, but I’m guessing insurance doesn’t cover this.
Insurance is usually covering it after you have failed X number of antidepressants.
@@jessicah3450 insurance doesn’t cover iv infusion therapy because it’s not fda approved and maybe other reasons. I’m starting in a couple days.
I am currently in a psychedelic therapies program. I have been learning from some of the best scientists in the field. I was instructed that Spravato, nasal routine for Ketamine, is not effective, one doctor said worthless according to studies.
Where is ur program or a program like it located?
Spravato works or me
I can tell.
Another question, if I may: Should we only get ketamine infusions from a place that employs anesthesiologists (sp?) to infuse it? I hope not, since such a requirement would eliminate many clinic choisces for many people, including me. But I prefer to know the truth. Thank you.
Not necessarily an anesthesiologist, though we understand ketamine better than anyone, but another physician who understands how to use ketamine safely and is medically trained to intervene if there is an adverse event. ER doctors can be very effective. A psychiatrist who works closely with a CRNA can be a great combination. You need one person who knows both mental health AND ketamine or a team of people who can provide complete care when working together. IV infusions are the gold standard, safest, and most effective.
No disassociation at all totally coherent.
Are you referring to Spravato or with IV infusions? If you're referring to IV, you may have gotten a very low dose. We try to get our patients at the right dose which is normally some level of dissociation.
@@KetamineClinicsLA did infusions then doc gave me 10mg ketamine spray I don’t feel much of anything seems to only last 10 minutes or more
@@KetamineClinicsLA The infusions we’re very intense.But even those just very extreme heightened sense there was a dissassociative effect but no hallucinating or out of body.But this at home nasal spray seems like garbage.
@@KetamineClinicsLA I sent him your video on dosing but not sure if he saw it yet.
@@KetamineClinicsLA So what dose for 145 pounds should I have on the ketamine nasal spray it’s not Spravato but I assume it’s the same only cheaper .lol
Wich other alternatives are there especially when you have tried a lot of different medications and psychotherapies.
ketamine infusion therapy, TMS, and soon, mdma and psilocybin.
Can ketamine or spravato help schizophrenia? I have severe negative symptoms, anhedonia, lack of motivation, and social isolation. I was told that ketamine in known to treat anhedonia.
ketamine can be very helpful for anhedonia, lack of motivation and social isolation, however, we are extra careful when someone has a diagnosis of schizophrenia since ketamine is a dissociative and there is a possibility that it could make delusions and such worse. If you are interested in speaking with us further about your specific situation, please call our clinic directly at 310-270-0625. Thank you!
If you need a spiritual breakthrough or an ego death, recreational purposes? Mental help PTSD, anxiety, ADHD, shrooms,lsd, DMT, chocolate bars.All you need is psychedelics and a good reliable source to purchase, shamans online 24/7 to assist through your struggles, check out @morgan_drugz page on Instagram for quality psychedelic products..,
I have done both and infusion is wayyyyy better and more psychedelic like. The spray doesnt seem that great during treatment. Like you took a sedative.
I have treatment resistant depression...Been treated for 30 yrs and still struggling...I'm concerned if this Spravato treatment will show up on a random drug test? As I'm a Commercial Driver with CDL???
I'm not sure how long the Spravato would show up, however, it would not be more than a day or so depending what type of test is done. You can always receive a treatment letter saying this is for medical purposes! Feel free to call our clinic to discuss this further 310-270-0625.
I wish this would be covered by insurance
If you have a PPO plan there is a possibility that Spravato will be covered by your insurance. You can ask your psychiatrist to help you look into it since it will require a referral from one. Ketamine Infusion Therapy has also been partially covered by some PPO plans if you have any out of network reimbursement and have hit your deductible. Please feel free to reach out with any additional questions! 310-270-0625.
Why did they choose the S isomer?
Hi there, great question. At the time that the manufacturers were in the initial stages of research, it was believed that the S isomer had less of a psychoactive effect than the R isomer, which was considered to be an undesirable effect. However, it is now believed that the psychoactive or dissociative effect is an important aspect of treatment. The R-isomer is being researched and people are actively working toward patenting it for the treatment of mood disorders. If you have additional questions, please don't hesitate to reach out to our Patient Care team at (310) 270-0625.
Is the "s" the only form for nasal treatment?
There is ketamine nasal spray and also "esketamine"/Spravato which is only the "s" isomer. These are two different types of nasal spray.
I just picked up my script. It's ketamine hydrochloride. As nasal spray. I have to call my Dr though bc it just says to take 1-2 sprays in each nostril. Anything I've seen says to take only 2x a week or every other day.
I am taking the compounded ketamine spray. Tonight will be my 4th dose and it is definitely working. However, does this affect cortisol? The first 2 nights I was "thrown" awake in the middle of the night. I felt it was my cortisol levels.
@@elliemae4887 I'm not sure about that, I'm sorry! I would ask your ketamine provider :)
Ketamine tried it and I went into hallucinations and the doc took me out
He said ketamine occurs in nature. Where is this natural source?
parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-020-04402-w
Occurs naturally yet someone patents it 🤔
Same as water.
Patenting the S isonemer is how they can make money off a generic ketamine medicine. Strictly business move.
Of course it is more expensive, big pharma
H6
What the doctor is trying to say is that IT IS BAD FOR HIS BUSINESS, he’s probably never even given a dose.
Hi there. Dr. Mandel is an approved provider of Spravato and it is currently offered at Ketamine Clinics of Los Angeles should patients elect this treatment over IV. Patients opt for IV Ketamine Infusion Therapy because it is backed by a substantial amount of research and studies over nearly 20 years. The Ketamine Advocacy Network has an abundance of information regarding the importance of the route of administration which we encourage you to check out!
Ketamine Clinics of Los Angeles Fair enough. Just for the sake of conversation It’s still less lucrative I would imagine. With that being said, as we say in my business (Automotive retail) “profit in not a bad word, the man has a right to make a living for the help he provides. I’m certainly not one of those people who is for some sort of socialized medicine program. When you take money out of medicine you want up getting what you pay for literally and figuratively. Smart people who would wind up going to a great university and becoming phenomenal doctors wind up going into finance and running a hedge fund or something, I want my doctor wealthy/comfortable so he can focus on what he’s doing and be motivated. My “bad for business“ statement was not meant to be pejorative. Anyway, Are you guys affiliated with anyone on in the NY area?
@@mog882 Hello there. We're not affiliated with anyone in the NY area, unfortunately. We have one location in Los Angeles, CA. If you would like to find a provider near you, there is a great directory available at: www.ketamineadvocacynetwork.org/provider-directory/.
@@mog882 the health insurance industry/big pharma are the ones making the trillions in profits while 80.4M working americans cannot afford healthcare, it's not the medical providers but the insurance industries who prevent much needed care for somany, unlike literally every other first world nation does for it's citizenry who pay taxes
Haha sales BS. Advocating for a non FDA version of drug.
Healthcare for the rich. They do not accept insurance. I find that despicable.