since i was pharmacy student i used to watch your videos before mid & final exams and it help me to remember things & make it easier now i'm officially graduated pharmacist but still love watching your videos😅 so i want to say thank u so much for making pharmacology easier on me ❤️🧸
I'm doing my b.pharm 3rd year right now.. Is there any scope for pharmacy after graduation???? Because, I don't see any scope in India as they are paying very low for the pharmacists.
It's nice to have a diagram of the cascade and then interject each drug class where it acts. Thank you! This is how all topics should be taught by all teachers!
The overall video was great. I would just like to note that the Mechanism of Action for Fondaparinux is incorrect. Fondaparinux actually binds to Anti-thrombin III and potentiates its selectivity and affinity for Xa. Fondaparinux is in fact Anti-thrombin III mediated which is what distinguishes it from the direct Xa inhibitors (ApiXAban, EdoXAban. RivaroXAban and BetriXAban) which are not Anti-thrombin 3 mediated.
Coagulation cascade are the ones I found hardest at med school and it was a pain to revise when comes to finals then I forget about it. Now I'm preparing for core training exams and actually find this video more helpful than ever. I never understood this topic any clearer (I guess with more clinical experience it also helps to understand bit more). Thanks so much for making this video.
Correction to MOA - Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin
Please keep making those videos, it was organized, simple, and really straightforward. You just save my 5-hour listening to recording lectures. Thank you so much
I watched the first video from your channel 6 years ago when i was in semester one 1 trynna understand autonomic NS drugs. and now I am doing my internship and wanted to revise. thank you for being with me throughout the journey
Thank you for the great video! The reversal agents discovered after this video was made: for apixaban it’s andexanet alfa, and for dabigatran it’s idarucixumab.
This was perfect from beginning to end. Information logically categorized, great talking speed, use of graphics that helped anchor understanding... bless you for taking the time to make this! First time seeing your videos, instantly subscribed. Looking forward to watching the rest of your videos through Pharmacology class!
I am self studying some medical subjects without requisite chemistry and without other helpful pre medical information. Despite the brain damage I got from this, your lecture has really helped me understand the activity of aspirin in coagulation. Huge thanks for uploading this, it has been a great help to me 😎
Oh my god! I was literally waiting for the upload of video on this topic. Sir, You make learning process in pharmacology so simple and easy to understand. I owe all my good marks to your lectures! Thanks a ton❤
just a quick errata; eloquis/(apixaban), xarelto (rivaroxaban) have an FDA approved reversal agent "Andexxa, the first factor Xa inhibitor antidote indicated for patients treated with rivaroxaban (Xarelto) and apixaban (Eliquis), when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding."
Thank you so so SO much for this video. I'm a medical student and have struggled so much with these drug classes for a long time. When I get a question in my exam about this I'll be thinking about this video haha. It was perfect. :)
Great summary video! thanks for the post. It was very helpful. I like that you give examples of all the drugs in each class and their mechanisms with visuals. This helps to solidify the information for visual learners.
霜夜 彬 how long is it going to take you to graduate and eventually get a job? Let’s pretend for a second that I am in a college that’ll allow me to earn my pharm.D then graduate. Can I then go into the field from which I studied?
@@Onmymind1 you need to complete all the prerequisite courses in undergrad and then apply to pharmacy school. I'm in my 2nd professional year of pharmacy school. The program has a total of 4 years.
Outdated. The extrinsic pathway activates the intrinsic pathway. Blood vessel damage activates the extrinsic pathway leading to thrombin formation. The thrombin then activates the intrinsic pathway. Both pathways are always activated together which explains why all the coagulation factors are needed. A deficiency of any intrinsic pathway factor or any extrinsic pathway factor will lead to haemorrhage. That is why we use fresh frozen plasma in our trauma cases. DO NOT think of the extrinsic and intrinsic pathways as being separate. They were only separated by the necros (pathologists) for lab testing.
thanks for the awesome explaining! PS: directly after the video in 2018 an antidote for factor 10 inhibitors (rivaroxaban and apixaban) was released named Andexanet Alpha! 🙂
Thanks, now I understand my case. I have DVT and my doctor give me Xarelto 15 mg 2 x a day for 3 weeks, then 20 mg daily, now I am taking Xarelto for 6 months , now, with Pt ,PTT and ultrasound of venous and arteries of my lower legs Please help me know more of my case, thank you
Buddy ... You are making things damn easy ... Thanks for making such a informative video ... combining all three classes of medications was good idea...
According to Wikipedia and PassMedicine, Fondaparinux binds antithrombin and accelerates its inhibition of factor Xa. In your video, you say it does not bind to anything. Correct me if I am wrong or edit the video to avoid misleading.
Thank you sir for this video.. Excellent video 👌of totally information about all coagulation,anti coagulation,anti platelets,thrombolytic. Thanking you..
![Antihypertensive Drug Chart: Pharmacology Made Easy [Classes, Medication Trick, Mechanism of Action]](/img/1.gif)
🚀 Elevate Your Pharm Game! 📚 Join Patreon for A+ Study Notes!
👉 www.patreon.com/speedpharmacology 👈
Perfect
Update: an antidote for apixaban and rivaroxaban is now available: Andexanet alfa. Came out in 2018, one year after this video was uploaded.
thank you for information
Thanks 👍👍
Thank you
Also, Dabigatran has an antidote, Praxbind
Idarucizumab a monoclonal antibody
since i was pharmacy student i used to watch your videos before mid & final exams and it help me to remember things & make it easier
now i'm officially graduated pharmacist but still love watching your videos😅
so i want to say thank u so much for making pharmacology easier on me ❤️🧸
From which country are you from Ma??
I'm doing my b.pharm 3rd year right now.. Is there any scope for pharmacy after graduation????
Because, I don't see any scope in India as they are paying very low for the pharmacists.
It's nice to have a diagram of the cascade and then interject each drug class where it acts. Thank you! This is how all topics should be taught by all teachers!
The overall video was great. I would just like to note that the Mechanism of Action for Fondaparinux is incorrect. Fondaparinux actually binds to Anti-thrombin III and potentiates its selectivity and affinity for Xa. Fondaparinux is in fact Anti-thrombin III mediated which is what distinguishes it from the direct Xa inhibitors (ApiXAban, EdoXAban. RivaroXAban and BetriXAban) which are not Anti-thrombin 3 mediated.
Coagulation cascade are the ones I found hardest at med school and it was a pain to revise when comes to finals then I forget about it. Now I'm preparing for core training exams and actually find this video more helpful than ever. I never understood this topic any clearer (I guess with more clinical experience it also helps to understand bit more). Thanks so much for making this video.
Correction to MOA - Fondaparinux selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin
under the phosphodiesterase inhibitors, how did we go from increase in cAMP to decrease in ca2+????
@@humaameersupposedly it should be increase in Ca2+ right?
Please keep making those videos, it was organized, simple, and really straightforward. You just save my 5-hour listening to recording lectures. Thank you so much
I watched the first video from your channel 6 years ago when i was in semester one 1 trynna understand autonomic NS drugs.
and now I am doing my internship and wanted to revise.
thank you for being with me throughout the journey
Thank you for the great video! The reversal agents discovered after this video was made: for apixaban it’s andexanet alfa, and for dabigatran it’s idarucixumab.
This was perfect from beginning to end. Information logically categorized, great talking speed, use of graphics that helped anchor understanding... bless you for taking the time to make this!
First time seeing your videos, instantly subscribed. Looking forward to watching the rest of your videos through Pharmacology class!
ruclips.net/video/ynnPMgdEV5M/видео.html
You are conveying little faster
And your slang make it us difficulty in understanding in some places
I am self studying some medical subjects without requisite chemistry and without other helpful pre medical information.
Despite the brain damage I got from this, your lecture has really helped me understand the activity of aspirin in coagulation.
Huge thanks for uploading this, it has been a great help to me 😎
this video is absolute gold. thank you so much for taking your time to make this, you deserve an award.
I am not a doctor or pharmacist but after watching this video I understand each and everything about clotting.
bless you bro (Y) Thumbs up .
WHO KNEW IT WAS THIS EASY!!! I can't thank you even for saving my life
I was struggling with this for hours then I found your video
This is the freaking best!
ruclips.net/video/ynnPMgdEV5M/видео.html
Oh my god! I was literally waiting for the upload of video on this topic. Sir, You make learning process in pharmacology so simple and easy to understand. I owe all my good marks to your lectures! Thanks a ton❤
Avneeta Swashna
just a quick errata; eloquis/(apixaban), xarelto (rivaroxaban) have an FDA approved reversal agent
"Andexxa, the first factor Xa inhibitor antidote indicated for patients treated with rivaroxaban (Xarelto) and apixaban (Eliquis), when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding."
Even Dabigatra has an antidote: Idarucizumab
Amazing video. I have been struggling with this topic but this has made it very easy for me . Thank you.
I would just like to say thank you for captioning your content! As a subtitle person, you're making it easier for me to learn, so thank you.
Ever since I found His videos ,I have improved in my pharmacology and pharmacotherapeutics✌
I have just discovered you and u have no idea how grateful I am.
Excellent presentation. Thank you.
thanks for keeping your lectures short, simple and to the point
Thank you for videos..you make me attention for this mechanism
Thank you so so SO much for this video. I'm a medical student and have struggled so much with these drug classes for a long time. When I get a question in my exam about this I'll be thinking about this video haha. It was perfect. :)
Glad you liked it!
U brought peace to my mind u deserve a Nobel prize
God bless the authors of the internet. I have a test on this in an hour and I have not managed to even read it.
I am fortunate to find your channel and watch your lectures. They are directly oriented to the point and easy to understand. Thanks so much!!!!
Great summary video! thanks for the post. It was very helpful. I like that you give examples of all the drugs in each class and their mechanisms with visuals. This helps to solidify the information for visual learners.
best pharmacology explanation ever!!!!
Hi, Can you make video on Antiemetics..
And Thanks a lot for making the toughest topics of pharmacology EASIEST..!
Excellent video. Well organized, clear, and logically explained. Thank you!
One word speed learning pharmacology.. thank you sir..
exam tomorrow. Really help me understand more ! thank you !
Thank you so much for all your hard work in making these!!! I feel so much better after watching your videos! You are an absolute blessing
EXCELLENT - perfect for nursing students. Thanks for making this!
Dude, this is awesome! Thnk you from a struggling pharmacy student.
I am in pharmacy school. I watched this last year in pharmacology. Now I am watching this for my therapeutics class.
霜夜 彬 how long is it going to take you to graduate and eventually get a job? Let’s pretend for a second that I am in a college that’ll allow me to earn my pharm.D then graduate. Can I then go into the field from which I studied?
@@Onmymind1 you need to complete all the prerequisite courses in undergrad and then apply to pharmacy school. I'm in my 2nd professional year of pharmacy school. The program has a total of 4 years.
Thank you so much! I can't believe I was struggling with them from 2 hrs and I got it at once or twice from a 16 min video.
Wow! You are gifted to teach.
Outdated. The extrinsic pathway activates the intrinsic pathway. Blood vessel damage activates the extrinsic pathway leading to thrombin formation. The thrombin then activates the intrinsic pathway. Both pathways are always activated together which explains why all the coagulation factors are needed. A deficiency of any intrinsic pathway factor or any extrinsic pathway factor will lead to haemorrhage. That is why we use fresh frozen plasma in our trauma cases. DO NOT think of the extrinsic and intrinsic pathways as being separate. They were only separated by the necros (pathologists) for lab testing.
Very clear and so so helpful! Thanks a lot! It has been long time it was not clear, but now it is, praise the Lord! :)
You are totally genius man...thanks for your hard work...that make our understanding to pharmacology very easy..a billion thanks to your work
Brief but very educative! Thank you. God bless!
thanks for the awesome explaining! PS: directly after the video in 2018 an antidote for factor 10 inhibitors (rivaroxaban and apixaban) was released named Andexanet Alpha! 🙂
it is actually an Pseudoreceptor for the drugs that keep them from the Xa factor receptors!
All the important points are wonderfully covered with clear explanation 😍😍
The best lecture so far of this very complicated topics and the use of picture aids is just superb!❤
I loved this- straight to the point.
you are an amazing person who make everything in pharmacology easier and simple (may god bless you )
Thank you, Short and sufficient 👍🏼
dude you just saved my life, thanks for the vid
Lots of helpful videos by speed pharmacology, thank u.
Such an amazing talk. Really made me understand this topic
I urge you to plz make more videos. Superb videos. You are doing amazing job.
Fantastic video on anticoagulants
your channel is a discovery 4 me
Thanks, now I understand my case. I have DVT and my doctor give me Xarelto 15 mg 2 x a day for 3 weeks, then 20 mg daily, now I am taking Xarelto for 6 months , now, with Pt ,PTT and ultrasound of venous and arteries of my lower legs
Please help me know more of my case, thank you
Very clear , coherent and insightful
The best video of the topic! Thank you!
Really thanks for this useful video😘
Buddy ... You are making things damn easy ... Thanks for making such a informative video ... combining all three classes of medications was good idea...
I can't thank you enough, God bless you, may you achieve more than what you wish for💕
According to Wikipedia and PassMedicine, Fondaparinux binds antithrombin and accelerates its inhibition of factor Xa. In your video, you say it does not bind to anything. Correct me if I am wrong or edit the video to avoid misleading.
I have ttp and this really help explain why certain drugs aren’t safe for me to use
Thank you so much sir
My mind was just blown 🤯🤯🤯 absolutely awesome video! I highly recommend! Very helpful 👌
Sir, this video is very helpful. After watching this video, all my doubts on antiplatelets and anticoagulants are cleared.
ruclips.net/video/ynnPMgdEV5M/видео.html
Can you take omoprazole 20mg with blood thinners
you are literally a life saver!!! thank you so much for making my life and concepts easier. God bless you
Perfect lecture for Anticoagulants and Antiplatelets
enjoyed ????? buddy u r better than my uni lecturer THANK U
Thank you..you saved my time
Thanks.... Everything in one video
you are the best . the video is awesome you make me love pharmacology thanks & please continue
7:39 anticoagulan
14:15 trombolitic
2:07 antiplatelet drugs
Thankyou Soo Much Sir
Love From India ❤️
Thank you so much, so clear and simple
May God bless you
Exactly what I needed. Thanks
this is the most awesomest video ever . i ama pharmacy student and all your videos has made my studying so easy . thanks alot
I love your videos! Please keep up the great work!
Excellent video! Covers everything. Really grateful to you for making this!😀
thank you thank you very much didn't simply enjoy...was just awsome
These are SOOOOO great! thank you for posting! Can you make a video explaining Antipsychotic drugs?
Thank you so much for making this topic understand in just 16 minutes :)
Thank you sir for this video..
Excellent video 👌of totally information about all coagulation,anti coagulation,anti platelets,thrombolytic.
Thanking you..
wonderful explaination!!!
I discovered this video on Pronto Therapy Folio - there are plenty more great videos there that will help out
Sir make more videos as soon as possible
Muhammad bilal Coz we have to pass in our 2nd MBBS..LOL
Yup Mohit & I'm in 3rd yr Mbbs exam
We've pharma in 3rd yr Mbbs
ruclips.net/video/ynnPMgdEV5M/видео.html
Beautiful explanation. Thank you!
thank you for this video
great job
Man you’re the best... love your lectures~
thank you so much. the drawings really help me understand much more than powerpoint slides alone
Well simplified... Great job..
Thank you.
Thanks for this video very informative
thankz for your explanation, its so helpfull, cant wait your next video..
Beyond the best.
Thank you so much,sir...
This video helped me to understand the topic crystal clear🎉
YOU ARE AN ANGEL...
Please make videos on other topics ....it's really a good aid for us in pharmacology .....
The best explanation