Lipid Lowering Agents (Cholesterol Drugs)

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My goal is to reduce educational disparities by making education FREE.
These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
For educational purposes only; NOT medical or other advice.
Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
Opinions are entirely my own.

[@madinaradjabova1668]

HM*G (good for) *CO A (coronary artery)

[@rachael4775]

this is literally the most brilliant little trick ever my jaw is on the floor hahha

[@ruzan6386]

Genius. Will never forget this

[@erikramos1972]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@TheRyanChang]

for PCSK9 inhibitors
Pesky (PCSK-9) muhammad ali (ALIrocumab) Evolved (EVOlocumab) boxing.
This also helps us remember the side effects because you have NEURO effects and soreness (mylagias) from boxing

[@nehadharap700]

ahhh,THANKS DUDE!

[@ruzan6386]

Thank you!

[@justaryana]

Dirty, you did it again. you really did do a better job teaching this than ANYONE else. and in the nick of time for my exam!

[@hehateme1187]

To remember the ↓ LDL exceptions, Fibrates and Niacin, I added this little mnemonic:
fibra↓Tes (↓ TG) and "Nancy is extra Hot!" (Niacin - ↑ HDL - flushing)
For remembering the majority decrease LDL, I remember "All the fatties drop it LOW LOW" (Lipidemia drugs ↓ LDL lol)

[@tesnimhamdan5813]

My exam is in 2 months and your videos are so essential during this period. You just simplify everything, especially pharma which is so hard to memorize. I watched your video on HIV drugs and I answered the UW questions like it was nothing. Now I guess the lipid lowering agents will be a piece of cake as well. Thank you so much!

[@user-eb3ni4bz9q]

Dude, you're like a magical teacher that I go to when ever I stuck in a subject.

[@palomiichimplin2855]

Thank you so much for your support 🇪🇸👏🏽👏🏽👏🏽

[@yashpawate1306]

Perfect time for my pharm test tomorrow. Thank you so much!

[@doom_inik]

exam in 10 days, coming in clutch with this topic cause first aid had a lot going on with those visuals (same with sketchypharm), but you made this v easy to follow👍

[@fireman00742]

Dirty medicine is by far my favorite learning tool. I have not purchased a text book in my FNP program yet. Thank you !!!

[@georgiabessie]

How’s school going? I’m in year two FNP. I love these videos.

[@uswahsiddiqi238]

Thank you so much! Will definitely support via membership once I start earning! THANK YOU

[@anacarolinacostapontes5506]

Hi!!! Greetings from Brazil! I love your videos! They are incredibly objective and accurate! I just wanted to say thank you so so much and please keep it up! Also, just a small correction: estatins are actually competitive inhibitors and not alosteric inhibitors: they bind to the active site of the enzime HMG-CoA-redutase, taking the place of the substrate HMG-CoA, as opposed to binding to the allosteric site and inducing a conformational chance of the enzime that makes the binding of the substrate to the active site impossible.

[@GabrielSantAnaCarrijo]

In portuguese they translated "Bile acid resins" to "Bile acid kidnappers" which is just 1000% better

[@VivaLaVittoria]

Great video. I'm currently studying to be an FNP and your content gives such great overviews of different content areas.

[@yummy1857]

It’s a measure of how interesting your videos are when I’m watching them on my break after exams lol

[@sanjananayak4348]

Thank you so much! You have no idea how much anxiety this topic gave me before this video.

[@sarasims2207]

really was the best explanation i ever heard thus far ! :)

[@lauraliranzo]

WOOOOOW thank you so much! much love from DR

[@hivalee6992]

might be your best video

[@obeymadzingo6152]

thanks for the table at the end!

[@tjm1434]

Just what I needed. High-yield.

[@ekrajghai6525]

Thank you so much dirty medicine! Watching your videos makes me forget all the other resources Im using.

[@bitewmekonnen5862]

what an awesome explanation!!

[@RidaZayn]

The best explanation, Thank you 👍

[@ann26614]

Thank youuuu so much!!! THIS literally saved me!

[@usmanwisa3386]

Excellent explanations

[@mariamshabbir198]

Amazing Lecture!

[@ksharma103]

Much needed!!!!

[@MedManiac1]

thank you for saving my life!! 😭😭❤️❤️

[@shanazannaleeguptar8075]

I used your channel and I passed pharm 1, using rn to see if i can pass pharm 2, great work sir

[@JaehoonWrestling]

Your lecture is so easy to understand and ty for your contribution!!!

[@duocphamtruongtho4462]

Its so helpful, thanks so much!

[@nurula1783]

running out of things to comment in your videos but they really are helpful

[@deeeeep806]

super helpful video, thank you!!

[@user-vt5eg5zj1e]

Thank you very much bro. 🥰

[@nola-baissa2433]

Great video as always. What about Thiazolidinediones?

[@garrettmorgan9926]

Thanks Dirty! Mnemonics: NPCs are Eze. LFTs are Eze. EzetimIBe Intestinal Brush border.

[@uzmabaig465]

Thank u so much for this video

[@professorcensored3647]

9:47 "but who cares?" cracked me up. Thank you

[@priyam1550]

Thank you!

[@dream_catcher430]

Thank you very much 🙏

[@alih6953]

Thanks

[@xaaboopinkly]

Thanks sir!

[@drdianellyspintobenamaraap5935]

love this channel

[@vietle1313]

this man the goat

[@manjushreeinamdar1242]

Thankyou God sent angel

[@shen3998]

Amazing work dude 👍keep going

[@Nishamukherjee1995]

Thanks a lot sir

[@jhalajayraj130]

Life saver video

[@veenaveena797]

Your teaching method helps to register and retain facts...

[@omnasharma955]

Could you please make a video on diuretics? Thank you

[@Army_Dentist]

Dirty you are super clean with concepts🎉😅👏🏻

[@nasimmalakoti7031]

You're amazing

[@umairjaved4755]

@Dirty med my exam is next month. Kindly upload one video on Adrenergic system.
P.S: Thank u so much for every video. May God bless u for that

[@25lizfair]

Thank you for the video! one thing to clarify...don't fibrates also increase HDL? via PPAR-a? the take-home points at the end only point out that niacin increases HDL, and that fibrates just reduce trigs

[@yaalia.s9033]

cant thank u enough

[@TheRebellefleur27]

thank you

[@moob2020]

Can you please upload a video about opthalmology (especially fundoscopic images )

[@sdnyanzi]

No

[@maryemmallick2752]

you promised making it easier for us and you kept your promise. KUDOS😍😇

[@Azhrxy]

So thank y dr.

[@adaezenwankwo6754]

This guy is good

[@zorrento14]

My exam is in June and I'm clenching my pearls rn

[@Kittendoc]

Same

[@HuevoBendito]

Mine's in July. We got this!

[@drmoctarali7385]

From somalia you are one in billion

[@williamkudiewu1032]

Dirty is crazy man love this guy

[@grace_cee9335]

Thnk u so so much

[@moji1466]

Not the nerdy academic career 😂 ! Great video

[@bandanaghimire6427]

Good

[@thesweetpotatogirl]

Thnk you🌟🌟🌟

[@beatriz.e.m7545]

hey just a question because you had said the Fibrates second pathway via PPAR a increases the HDL: which would mean that HDL would be increased for both Niacin and Fibrates how come you only put a decreased quantity of triglyceride in fibrates?

[@josephakalonu1052]

HDL would be increased by Niacin only.

[@omerhaseebkhan]

salute to u

[@ahmadcheema7198]

Thank you ^_^

[@globularfish2074]

You can use "NPCs wearing TIMs are at the IBorder" for the ezetimibe if you need a mnemonic

[@lauraliranzo]

You are theeeeee besssttt!

[@AhsanKhan-wo2ql]

Its the mnemonic juicelord himself

[@mohannedjamal9471]

amazing, just wanted to mention that resins can increase TGs by increasing VLDL

[@johanlalnunmawia3818]

Wow ! Really 😲

[@zuhramuskan5563]

HOW?
WILL YOU MIND TO EXPLAIN IT

[@elizabethdean1209]

Thank you for your incredible generosity in the work you do! You are making the world a better place in a big way! Have you ever considered a life time membership option? I would love to support your work and my ongoing education for life. Dr. Been has the option of one time payment for unlimited access and I love the idea! ✌️ Liz Dean

[@nigelwang2447]

Primates bring stones to the PPARt-ay 😂

[@padmajahawaldar4319]

Thank you dirty ❤

[@arizonablossom8635]

Thanks a lot dirty medicine🙏

[@meethamallawati850]

Please come and teach at our college

[@shanemckenzie8681]

Not being mean bro, but your voice soothes me to 😴 stay awesome

[@unicornspoops]

Sketchy pharm is insane for this topic. It explains the physiology but its convoluted and difficult to remember bc of that. I'd say dont bother with it and use this with FA instead.

[@AN-zg3sr]

Cholestrol is not bad it's the oxidised lipids which are nd in presence of glycation..the combination results in CVD

[@graywolf2600]

Do you have a source on the dementia adverse effect?

[@DirtyMedicine]

Bottom line seems to be that FDA was concerned enough about cognitive changes. Be it statistically significant or not, it is worth knowing about imo:
link.springer.com/article/10.1007/s40264-015-0296-6
www.ahajournals.org/doi/epub/10.1161/CIRCRESAHA.118.313238

[@darkmoon3646]

DIRTY U FREAKING LEGEND

[@puneetgill4994]

💯

[@TheGhadaelarbash]

Note: PPAR-Gamma was mentioned in the insulin drugs "Bring Glitta to the party"...Glita was the drugs of TZDS and Party MoA

[@Angielle_]

❤❤

[@joshmcgoo]

commenting for the algorithm

[@user-sb1ku5hq7h]

Love from Russia 🎉

[@deadricchampion6856]

Based Dirtymedicine

[@UsmleAspirantPediatrician]

What I think is that although you eat fibers so that you don’t get POOP STONES, FIBRATES make you stones 🧐

[@Lights0ut]

Find the odd one out
1. Atorvastatin
2. Simvastatin
3. Nystatin
4. Rosuvastatin

[@TusharMathapati.]

Nystatin because it is antifungal and others are not

[@jamesgordon8867]

Where is Chromium?

[@sleepytraveler369]

No mention of gallstones with bile acid resins? Wtf dirty

[@kayallen7603]

statins = yuck.

[@neya732]

thank you so much dirty

[@MatanLinevitz]

Dirty, you are that guy. Thank you for contributing to all of our success!! You are a great teacher and great person in general!

[@amanydubai7880]

Thanks