Cancer Drugs/Pharmacology

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  • Опубликовано: 19 май 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Комментарии • 141

  • @johnhancock2920
    @johnhancock2920 4 года назад +393

    I have never loved someone that I have never met so much

    • @nyembidee1
      @nyembidee1 11 месяцев назад +2

      Totally agree 💯%
      love you @Dirty Medicine!!

    • @foodiesworldUSA
      @foodiesworldUSA 10 месяцев назад +3

      Love you @Dirty Medicine

  • @itzBarto
    @itzBarto 4 года назад +289

    Mnemo I use for Doxorubicin /Daunorubicin:
    They both end in -rubicin -> ruby (= red) -> the heart is red -> cardiotoxicity
    Dilated cardiomyopathy because it starts with D like Doxorubicin
    Dexrazoxane used to prevent it -> also starts with D and sounds like Roxane ('Roxane, you don't have to put on the red light', song by the police) -> again red for RUBYcin and heart
    Hope it helps someone :D

    • @alih6953
      @alih6953 3 года назад

      ty

    • @yaraelhefnawi7632
      @yaraelhefnawi7632 2 года назад +3

      Funny things is doxorubicin is actually a red solution and is known as ‘the red devil’

    • @mirbear72
      @mirbear72 2 года назад +1

      That's a good one

    • @crystallemmon2830
      @crystallemmon2830 5 месяцев назад +2

      This is perfect!!! Thank you 🙏🏾

    • @Seniors11
      @Seniors11 4 месяца назад +1

      Thank you! I sing the song Roxanne every time I see the drug name now lol!

  • @ayshasarmad1240
    @ayshasarmad1240 4 года назад +112

    You have no idea how much I pray for you each night you are an angel, I was praying to GOD that you make a video on cancer drugs and the video came ,May God always always always keep you happy and blessed

    • @alih6953
      @alih6953 3 года назад +2

      May GOD bless you as well well wisher

  • @shayguthrie7098
    @shayguthrie7098 11 месяцев назад +28

    I just passed STEP 1 so I am coming to reply to my most favorite Dirty mnemonic ever!! Vincristine and Chris Christie Bridgegate. I remember this one soooo well! Thank you for all you do. As soon as I am making money I am totally joining the channel.

  • @2468ayesha2468
    @2468ayesha2468 4 года назад +66

    Where is the ad. I want a few ads in your videos you deserve them👍🏼

  • @stephaniefabara2520
    @stephaniefabara2520 4 года назад +97

    Just to share my mnemonic for Topoisomerases
    I can
    2 (to the) side
    so,
    "I can" is topoisomerase 1, which ends in CAN
    "2 (to the) side" is topoisomerase 2, which ends in SIDE

  • @davidrios1492
    @davidrios1492 4 года назад +11

    I have a test on Tuesday and I went from feeling I was going to flunk to feeling good in just 30 mins. THANK YOU!

  • @stacymoroz4709
    @stacymoroz4709 2 года назад +19

    10/10 - Taking step 1 in a few weeks and pharm has always been my weakest subject. Thank you so much, your videos are so helpful!

  • @hamadrashid2285
    @hamadrashid2285 4 года назад +20

    Just a tip, for side effects the human image with corresponding drugs to organs is a great visual mnemonic in the First aid book.

    • @melissa90ify
      @melissa90ify Год назад +1

      I’ve seen the “Chemo Man” image used for this

  • @recht181
    @recht181 4 года назад +3

    I was procrastinating studying and then got your alert, so I'm gonna watch and start studying now. Thanks!

  • @umerhayat6857
    @umerhayat6857 2 года назад +9

    THIS WAS AMAZING!!!!!. Please do a video on anti tumor monoclonal antibodies!!!!!!!. They have started to come in questions a lot!!!!!

  • @pramodthapa2517
    @pramodthapa2517 4 года назад +2

    I was praying for this! thank you so much

  • @mukulgupta1495
    @mukulgupta1495 2 года назад +11

    For learning neuropathy for Paclitaxel: the "pathway"(neuropathy) of the bridge was blocked so you called a TAXI (paclitaxel)

    • @ajabisong
      @ajabisong Месяц назад

      That took a new pathway (neuropathy)

  • @ricardodias3541
    @ricardodias3541 4 года назад +3

    Thank you, Dirty! You are my hero!

  • @Capsmetro27
    @Capsmetro27 4 года назад +26

    Where's the old cancer drug video where you had the "it's time for the percolator dance" part, I remembered that video better

    • @dotri8099
      @dotri8099 4 года назад +1

      yeah i like that one better too

    • @omega3pictures
      @omega3pictures 4 года назад +3

      AGREED. "Piss-platin" for cisplatin is also much easier to memorize

    • @anita26069
      @anita26069 3 года назад

      @@omega3pictures oh yould you share this old one?

  • @DrAbdullahJadran
    @DrAbdullahJadran 2 года назад +2

    Excellent video, what an amazing explanation, thank you so much.

  • @DrBuntonDO
    @DrBuntonDO Год назад +2

    I don't know if this helps anyone but the way I remember the M-phases as well is by remembering that a bridge can sometimes fold up, separating them in the middle, kind of like what happens in a cell right after metaphase.

  • @tuqa2798
    @tuqa2798 4 года назад +4

    i miss your old way of explaining, you were very funny and energetic . please be your old you!!
    with my regards from iraq.

  • @DanielzeGreat
    @DanielzeGreat 4 года назад +10

    Can you upload the old video? It was shorter and easier to digest. I know this one is more complete, but it would be nice to have both versions. Thanks!

  • @alexbenitez2575
    @alexbenitez2575 4 года назад +31

    Hi, Dirty I’ve come across two different questions about the Alkylating Agents and they have had G1 and Cell-Cycle Non-specific as answer choices and both times it’s been CCNS. Resources checked were Becker, Boards and Beyond 2018 and Uworld. I have to say that I use your mnemonics all the time for memorization and on test day and have benefitted tremendously, but for this one specific thing I thought I’d give a heads up. Thank you for your content it’s been very helpful.

    • @Sammy.a1287
      @Sammy.a1287 2 года назад +3

      You're right. Alkylating agents are cell cycle non-specific

  • @MehF00L
    @MehF00L 4 года назад +2

    I have a final today on cancer. Oh my god, I'M SAVED!

  • @rainullah
    @rainullah 2 года назад +1

    Thanks for Explaining in such a better way 🙏🙏

  • @Mgggg500
    @Mgggg500 2 года назад +2

    Thankyou dirty !!!!!! You are an angel

  • @argumentumadbaculum
    @argumentumadbaculum 4 года назад +7

    I will never forget 5FU adverse effect, ever again.

  • @NLKEquestrian
    @NLKEquestrian 3 года назад +3

    this is probably the best video anyone can make for the driest topic in the universe. well done!

  • @hasansarhan9296
    @hasansarhan9296 Год назад +1

    This guy did made them super easy much easier to study than study them alone from a book

  • @raydavalosrd
    @raydavalosrd 2 года назад +3

    "What the hell are they asking me?"
    Me at every question

  • @bookbites101quotes
    @bookbites101quotes 4 года назад +2

    A great video , nicely divided , very high-yield . Thank you very much

  • @anukiran3
    @anukiran3 4 года назад +3

    God bless

  • @bookbites101quotes
    @bookbites101quotes 4 года назад +5

    Please make a video on immuno modulators and recent drugs

  • @sharanjhaveri6324
    @sharanjhaveri6324 4 года назад +4

    HEY , AMAZING VIDEO AS ALWAYS!! CAN yoU PLEASE DO ONE ON MONOCLONAL ANTIBODIES

  • @ko5737
    @ko5737 2 года назад +1

    Seriously ur such a saviour…👍🏻

  • @sadianusrat1237
    @sadianusrat1237 2 года назад +2

    Etoposide: E"two"poside. I don't know if anyone else shared that already but that's how I remember it.

  • @henrynnajiuba9591
    @henrynnajiuba9591 12 дней назад

    The Chris Christie thing was easily the worst memory aid I've ever come across in 20 years of undergrad and post-grad medical practice 😂😂. The 5FU/middle finger one is gold

  • @tafwolf
    @tafwolf 4 года назад +3

    Please do some videos on high yield bacteria, fungi, virus and parasites. Like agars, virulence factors etc etc

  • @M7mmad08
    @M7mmad08 4 года назад +1

    Very helpful, you are fabulous

  • @sweetfate80
    @sweetfate80 4 года назад +2

    you are so helpful thank you

  • @Patheticlife
    @Patheticlife 2 года назад +3

    TAXES are always increased so they polymerise microtubules.

  • @JustFe03
    @JustFe03 4 года назад +4

    amazing!! better than sketchy for sure!

  • @muskaninmed5860
    @muskaninmed5860 2 года назад +2

    YOU ARE LITERALLY A GOD-SENT ANGEL

  • @srana5049
    @srana5049 11 месяцев назад

    Thank you so much for this video!! You have actually made it super easy to learn.

  • @ayushi3392
    @ayushi3392 3 года назад +3

    Irinotecan, topotecan - 'I can' …topoisomerase-1
    Etoposide- '2 sides'…topoisomerase-2

  • @muhammedsiddiqui1270
    @muhammedsiddiqui1270 4 года назад +7

    Where's the percolator gone? It's time for the percolator , intercolating DNA !! Bring it back man!

  • @xmega456
    @xmega456 3 года назад +2

    youre amazing dude, thank you so much

  • @arlybrutus1198
    @arlybrutus1198 4 года назад +2

    Love the politics mnemonics you are a genius

  • @sabafarrukh1795
    @sabafarrukh1795 Год назад +2

    You say the cell cycle has been crammed into my brain since before medical school, but I, have sucked at understanding the cell cycle since I was 14 so hurrah.

  • @drswetaruparel
    @drswetaruparel 4 года назад +2

    Very very very helpful !!! 👍

  • @yasinyildirim4686
    @yasinyildirim4686 2 года назад +1

    This video is made by a beautiful and amazing human being!

  • @akash1yadav5
    @akash1yadav5 4 года назад +2

    Love you bro. Love 💕 from the 🇳🇵

  • @namir1782
    @namir1782 27 дней назад

    great video but the main moa of antracyclins(doxo-daunorubicin) is also inhibitting the topoisomerase2

  • @_maaal_husseinshakir2993
    @_maaal_husseinshakir2993 2 года назад +1

    thank you so much , from iraq

  • @ughsirius
    @ughsirius Год назад

    Thank you soooo much!!!

  • @johnheshbon
    @johnheshbon Год назад

    A clear explanation.

  • @zaranajam4231
    @zaranajam4231 4 года назад +2

    Superb👍

  • @abhisheksharma07
    @abhisheksharma07 Год назад +2

    You might wanna update this video as alkylating agents and platins are cell cycle non specific.

  • @sonyalvi6266
    @sonyalvi6266 4 года назад +3

    Thanks alot. This helps me alot 😭❤

  • @devwarner6880
    @devwarner6880 Год назад

    Wow! Great ! Thanks!

  • @dr.mitchellbradyd.o.7071
    @dr.mitchellbradyd.o.7071 4 года назад +9

    In the TAXI they had to take a different PATH.

    • @dookieshoes861
      @dookieshoes861 3 года назад +1

      Or sitting on the taxi for to long can make your legs numb!

  • @arvindkumarpt
    @arvindkumarpt 3 года назад +2

    Awesome thank you so much 🙏🙏 especially the s phase drugs they were killing me 🥴 , not anymore 😁

  • @omniaabumiddain5783
    @omniaabumiddain5783 4 года назад +4

    A genius! Thank you so much😍

  • @nathan9015cm9015cm
    @nathan9015cm9015cm 4 года назад +5

    Love you Dirty USMLE! Studying for step 1 now. Patreon for sure

  • @rikis7086
    @rikis7086 5 месяцев назад

    I made a different dumb mnemonic for Cladribine/Cytarabine: Tara likes pie, but Chad is a purist and won't eat anything unhealthy. Thus CyTARAbine is a PIErimidine analog, and CHADribine is a purine analog.
    Kinda silly but hope it helps someone!

  • @jamspice25
    @jamspice25 2 года назад +1

    Amazing!

  • @studywithramprasathrp3093
    @studywithramprasathrp3093 5 месяцев назад

    Hey sir, you are the best senior out there 😍

  • @akinwaleakinlade76
    @akinwaleakinlade76 3 года назад +2

    M phase Duplicate phase( m phase inhibitors). Inhibition of microtubules.
    Vincristine, vinblastine( prevent polymerisation, stops microtubules). Neurotoxicity, paclitaxel,( hyperstabilise M phase, makes it superstable) Neuropathy eribulin causes arthalgia.
    Gi ( cell duplication) phase inhibitors cisplatin,( nephrotoxicity)bulsulfan( pulmonary fibrosis) cytotoxicity, cyclosphamide( hemorrhagic cystitis), camustine,(cns toxicity).
    S phase. ( DnA phase)!
    Azathiapine : purine synthesis
    6 mecapurinol: purine synthesis xanthan oxidase
    Methotrexate myelosupression.

  • @OthmanMatar
    @OthmanMatar Год назад

    thank you

  • @muzamilmehmood3195
    @muzamilmehmood3195 3 года назад +2

    Thanks 👍👍👍

  • @amyma6463
    @amyma6463 8 месяцев назад

    Thanks for making it so simple 😩❤

  • @arlybrutus1198
    @arlybrutus1198 4 года назад +6

    so many funny moments the only thing is I cannot study around with you with my kids around lol

  • @bushraehsanullah2497
    @bushraehsanullah2497 4 года назад +3

    Hey please post your old video with the percolator it's better . This is good too ;) but post both

  • @tracey5301
    @tracey5301 2 года назад +1

    You are my hero

  • @eminemfan8203
    @eminemfan8203 3 месяца назад

    Bleomycin and busulfan blow out the lungs.
    I like your mnemonic but this one helps me so I am hoping it helps others as well!

  • @g.a.mylesii6677
    @g.a.mylesii6677 4 года назад +3

    Please please please- this is good but I need the old video!

  • @ayshasarmad1240
    @ayshasarmad1240 4 года назад +3

    Please any one just help with monoclonal antibodies used for which receptor nemonics and tyrosine kinase inhibitors uses

  • @MylaRayPereira
    @MylaRayPereira 2 года назад +2

    tenipoSIDE/etopoSIDE (topo II) -- there are "TWO SIDES" to every story

  • @chrizstele5922
    @chrizstele5922 4 года назад +11

    Paclitaxel starts with letter "P".. neuropathy has a "p" in the middle so...it can be memorized like that

    • @jayl5734
      @jayl5734 4 года назад +3

      i thought he was gunna say paclitaxel / neuroPATHy. People would have to take another route, aka another PATH, to go through the bridge or whatever. but yours is pretty cool too!

  • @crystaldolly9498
    @crystaldolly9498 2 года назад +1

    Can you make new video regarding hematology and oncology drugs added in first aid 2021?

  • @abigailfinkenauer4188
    @abigailfinkenauer4188 2 года назад +1

    so helpful!!!!!!!!!

  • @sharliferramroop724
    @sharliferramroop724 3 года назад +2

    omg thank you

  • @ryanthomas5148
    @ryanthomas5148 10 месяцев назад

    Such a good review 💯

  • @dotri8099
    @dotri8099 4 года назад +2

    miss your cytarabine old "mnemonic" :))

  • @aryanneupane5673
    @aryanneupane5673 2 года назад +2

    There are always two “ sides” to any thing. Etoposide and Teniposide = Topoisomerase 2

  • @ua7632
    @ua7632 8 месяцев назад

    Isn’t carmustine also bioactivated in the liver? 9:01

  • @ahmedelkheety3334
    @ahmedelkheety3334 2 года назад +2

    for etoposide just remember eTWOposide

  • @ameterasu13
    @ameterasu13 Год назад +1

    I know did Plasma cell dyscrasias, MPNs, Myelodysplastic syndrome, Lymphoma, Leukemia but doe we have to do this ? Necessarily??

  • @048mahamuuthafahima8
    @048mahamuuthafahima8 4 года назад +2

    Please Make a video about men syndromes pleases

  • @Vunami
    @Vunami 2 года назад +1

    Just want to let you know that Cisplatin arrests the G2/S phases.

  • @ramblingsofafutureMD
    @ramblingsofafutureMD 6 месяцев назад +1

    a way I remembered topsides and pecans topsides have 2 Es so topisomerase 2 and pecans have one e so topoisomerase 1. hope it helps

  • @taheraahmadi1723
    @taheraahmadi1723 Год назад

    ❤❤❤

  • @user-ro9py6pv7c
    @user-ro9py6pv7c Месяц назад

    IrinotecAN,topotecAN AN=1
    Inhibit topoisomerase 1

  • @ryanhiggins3477
    @ryanhiggins3477 3 года назад +2

    Taxis find a PATH through the city

  • @tumisangmakumula6232
    @tumisangmakumula6232 4 года назад +2

    no i take back what i said...it was before i watched the whole video

  • @foodiesworldUSA
    @foodiesworldUSA 7 месяцев назад

    Vinblastine I think it’s a different side effect

  • @eddyeddy7523
    @eddyeddy7523 2 года назад +2

    Dirty presents clean stuff

  • @bisratbisrat1081
    @bisratbisrat1081 5 месяцев назад

    There is always to sides so- drugs ending with sides inhibit topoisomerase 2

  • @akinwaleakinlade76
    @akinwaleakinlade76 3 года назад +3

    5 fluorouracil
    Methotrexate
    Hydroxyurea
    5 FU
    G2 Inhibitors.
    Topoisomerase inhibitor check if it wound correctly.
    Anti tumour antibiotics
    Doxorubicin( pulmonary fibrosis)
    Bleomycin: dilated cardiomyopathy.

    • @JJ-cn2ud
      @JJ-cn2ud Год назад

      Doxo=Detailed cardiomyopathy
      Bleomycin=Pulmonary fibrosis

  • @damienroland5350
    @damienroland5350 4 года назад +4

    If God had a disciple that was a video this would be it lol

    • @damienroland5350
      @damienroland5350 4 года назад

      Im re-taking my Step 1 exam next month and feel so much more confident now that I found this channel!

  • @wasim1880
    @wasim1880 4 года назад +1

    Please make a video on AIDS 😇

  • @vanshajchandra307
    @vanshajchandra307 3 года назад +3

    Dirty sharing mnemonics based on US politics and sports, meanwhile me, the poor IMG

  • @fadihamati10
    @fadihamati10 4 года назад +2

    Neuropathy is what you get if you sit in traffic for too long!