IL-1 "Gun" (man with gun shooting flames at a skeleton with a thermometer taped to its head. Macrophage mad in the background) : Inflammation, Bone resorption, fever, adhesion, secreted by macrophages. IL-2 "Shoe" (shoe that has a forcefield. Within the forcefield are 3 tea cups labeled helper, cytotoxic, and regulatory t cells. At the forefront is a natural killer monster guy): stimulates helper, cytotoxic, regulatory t cells, and natural killer cells. IL-3 "Tree" (Palm tree that is somehow promoting the growth of bone marrow behind it): Stimulates the growth and differentiation of bone marrow stem cells (similar to Granulocyte Macrophage-Colony Stimulating Factor) IL-4 "Door" (door says "Beg 4 Help!"): stimulates the growth of B cells, isotype class switching of IgE/IgG, differentiation of Helper T Cells. IL-5 "Bee Hive" (bee hive labeled "BAE hive"): promotes growth and differentiation of B cells, class switching to IgA, and growth/differentiation of eosinophils. IL-6 "Sticks" (Aisle 6 being blocked by sticks that are on fire. Beyond the door is a cute protein shake with a thermometer attached. Sitting on top is a mad macrophage: IL-6 promotes inflammation through vasodilation and increased capillary permeability. IL-6 promotes a fever and the cute protein shake = stimulates acute phase proteins. Macrophage makes IL-6. IL-7 "7-up can" (7-up can that has a poster attached which circles the lymphoid progenitor section in stem cell differentiation chart): IL-7 stimulating lymphoid progenitor cells IL-8 "8-balls" (8 balls everywhere that is being cleaned by an angry neutrophil janitor. Macrophage scared he will be cleaned up. Upset macrophage at the end): IL-8 recruits neutrophils to clear up infections. Macrophage secretes IL-8. IL-10 "fireman-cosplay Hen" (the fireman has a tagged beta fish): IL-10 attenuates the inflammatory response. TGF-B also attenuates the immune response by decreasing expression of MHC2, TH1, activated macrophages, and DCs. IL-12 "clock set to 12" (the clock screams "the natural killers have won" with a macrophage sitting on top): two functions of IL-12 by activating NK cells and promotes differentiation of TH1 cells. Secreted by macrophages. In the parking lot, there is an elephant raised on a tuna fish can leaking fluid and labeled "end white-haired granny cachexia! TNF-A" connected to a thermometer with a screaming macrophage: Tuna fish-elephant = TNF-A which activates Endothelium, causes WBC recruitment, maintains Granulomas, causes Cachexia in malignancy (vascular leak, fever, macrophages). Infinity Gum with a "G" on it within the parking lot with macrophages shooting lasers at a shoe: Interferon Gamma stimulates macrophages to kill phagocytosed pathogens and inhibits differentiation of Th2 cells. Induces IgG isotype switching in B cells. Interferons A,B interfere with DNA and RNA viruses. Adverse effects of interferons include flu like symptoms, neutropenia, myopathy, interferon induced myopathy, and depression.
At first I was like there's no way I can learn anything from this but here I am thinking of aisles in the store every time I need to know the function of a cytokine. Amazing.
Yooo im so grateful i found this video! I got midterms coming up tomorrow and this helped me greatly for my exam in immunology! More vids like these pls 🥺
I just wrapped up my 4 years of struggling to memorize all these interleukins in 10 minute long video! Thank you so much and I like a cute protein shake at 7:00🥰
IL-1 "Gun" (man with gun shooting flames at a skeleton with a thermometer taped to its head. Macrophage mad in the background) : Inflammation, Bone resorption, fever, adhesion, secreted by macrophages.
IL-2 "Shoe" (shoe that has a forcefield. Within the forcefield are 3 tea cups labeled helper, cytotoxic, and regulatory t cells. At the forefront is a natural killer monster guy): stimulates helper, cytotoxic, regulatory t cells, and natural killer cells.
IL-3 "Tree" (Palm tree that is somehow promoting the growth of bone marrow behind it): Stimulates the growth and differentiation of bone marrow stem cells (similar to Granulocyte Macrophage-Colony Stimulating Factor)
IL-4 "Door" (door says "Beg 4 Help!"): stimulates the growth of B cells, isotype class switching of IgE/IgG, differentiation of Helper T Cells.
IL-5 "Bee Hive" (bee hive labeled "BAE hive"): promotes growth and differentiation of B cells, class switching to IgA, and growth/differentiation of eosinophils.
IL-6 "Sticks" (Aisle 6 being blocked by sticks that are on fire. Beyond the door is a cute protein shake with a thermometer attached. Sitting on top is a mad macrophage: IL-6 promotes inflammation through vasodilation and increased capillary permeability. IL-6 promotes a fever and the cute protein shake = stimulates acute phase proteins. Macrophage makes IL-6.
IL-7 "7-up can" (7-up can that has a poster attached which circles the lymphoid progenitor section in stem cell differentiation chart): IL-7 stimulating lymphoid progenitor cells
IL-8 "8-balls" (8 balls everywhere that is being cleaned by an angry neutrophil janitor. Macrophage scared he will be cleaned up. Upset macrophage at the end): IL-8 recruits neutrophils to clear up infections. Macrophage secretes IL-8.
IL-10 "fireman-cosplay Hen" (the fireman has a tagged beta fish): IL-10 attenuates the inflammatory response. TGF-B also attenuates the immune response by decreasing expression of MHC2, TH1, activated macrophages, and DCs.
IL-12 "clock set to 12" (the clock screams "the natural killers have won" with a macrophage sitting on top): two functions of IL-12 by activating NK cells and promotes differentiation of TH1 cells. Secreted by macrophages.
In the parking lot, there is an elephant raised on a tuna fish can leaking fluid and labeled "end white-haired granny cachexia! TNF-A" connected to a thermometer with a screaming macrophage: Tuna fish-elephant = TNF-A which activates Endothelium, causes WBC recruitment, maintains Granulomas, causes Cachexia in malignancy (vascular leak, fever, macrophages).
Infinity Gum with a "G" on it within the parking lot with macrophages shooting lasers at a shoe: Interferon Gamma stimulates macrophages to kill phagocytosed pathogens and inhibits differentiation of Th2 cells. Induces IgG isotype switching in B cells.
Interferons A,B interfere with DNA and RNA viruses. Adverse effects of interferons include flu like symptoms, neutropenia, myopathy, interferon induced myopathy, and depression.
Wow, I feel so honored that you took the time to do that!!! Awesome!!!! Thank you so so so much. I am sure people will find this beneficial. Amazing.
This needs to be pinned.
At first I was like there's no way I can learn anything from this but here I am thinking of aisles in the store every time I need to know the function of a cytokine. Amazing.
=) Such a compliment! Thank you!
Me scoffing at the video the first 5 mins in, now me crying tears of joy revising this video before my exam!
=) Thank you for sharing ajane! I am so happy I was helpful!
I didn't expect to find something as fantastic like this, I am impressed and so grateful!
=) Such a compliment. .Thank you so much!
me laughing while studying immunology? i never expected that
thank u so much lol
=) So happy to hear that I made it fun! Thank you!
God bless you sir. You paved the way for many medical students. Thank you!
=) Thank you kevon!
Thank you so so much! This helped me study for an immunology exam
Thank you so much!!!
Yooo im so grateful i found this video! I got midterms coming up tomorrow and this helped me greatly for my exam in immunology! More vids like these pls 🥺
I am so happy I can help!!
I just wrapped up my 4 years of struggling to memorize all these interleukins in 10 minute long video! Thank you so much and I like a cute protein shake at 7:00🥰
Thank you! So happy to hear that I helped so much!!
I am watching this multiple times, such a fun and enjoyable video, thank you for making this.
Thank you yan!!! Such a compliment!!! I spent so much time on that one- I am happy it paid off!
Thank you so much for sharing your gift of teaching and creativity with the world. You actually made me day!
Such a beautiful thing to say - thank you so much!!
Man this was sooooo goofy, well thought out, entertaining and really hit home the points. Thank You!!!
You are welcome!! SO happy to hear that I was helpful!!
Your icon is so creative btw!
This story is the best way to remember all the cytokines! Thank you, very helpful and made it very easy !!!
Thank you Maria, I really appreciate the comment!
Oldschool windows xp and wii like animations are superb.. hope you keep up. Fan from Turkey
This video is so helpful! I always share it with my friends who are learning immuno. Thank you!
=) That makes me so happy to hear!! Yes, I still benefit tremendously from that video myself
Excellent! Was skeptical during the into (don’t use RUclips much for study) I was really surprised and loved your way of thinking
Such a huge compliment - thank you so much!
This is the best video I’ve ever seen in my life
=) That's the biggest compliment ever
I wish my teacher had a machine like that too. LOL!
=) I am happy you liked the video. Thank you!
God bless you AJ!!!!!🥲
Dude, this is Crazy!!
Thankyou for taking time out for people like us. 😇
You are welcome!! It's how I studied myself
This is pure gold, I love it
Thank you so much! I remember working so hard on that video. I am so happy you gained from it.
So underrated - amazinggg video and memory hacks!
Thank you so much Dr. Aayushi!
Wtf i love you!!! Thanks for creative videos like this😭😭😭
Thank you Mikaela! Kind words! I am flattered!
Wow.....i am very happy that i founded this ...
I am so happy as well!!
Awesome as usual. Thanks a million!
Thank you so much Binyamin! Really means a lot
A shout out for bro's work🔥
Wow ! Really nailed this one . Thankyou so much . 🎉
Thank you Swathi! So sorry for the delayed response to your nice comment!
your videos literally had saved my life!
I am so happy to hear!!! =) Thank you!
Soooo grateful for this work!!! This was da bomb!
Thank you so much!!
this is so unhinged. i love when academics get funny.
=) Thank you !
This helped a lot!
Thank you very much you don’t know how you help me
Such a compliment thank you!
Thank you very much.
I hope to complete all immune system in the same way
Thank you amal!! You can check out immunology videos at my website www.AJmonics.com Let me know if you need anything
Brooo this is too good can't lie so helpful cheers mate❤️❤️
Thank you! Sorry for my delayed response!!
Wow so easy to understand 👏👏❤️❤️❤️💯
So happy you found it easy to understand! Thank you for watching
I wish i could study like this. Thank you
I wish I could meet you one day! Thank you so much!
Thank you so much . It's really good.
=) Thank you!
This was amazing, thank you so much for this!
You are welcome optimisticbutt3rfly! (You gotta explain that youtube name to me!!)
Nice explanation
Thank you!!!!!!!!!
i love this so much!! thank youuu
Thank you so much Jahnvi! So happy to help!
Woah this is mesmerising. IL-6 - maybe that's a cute FACE protein
love it!
awesome ❤
=) Thank you!
Thankyou!!!! This is amazing
Thank you so much Shreya!
I am currently working on the review card for it - please check it out on my website!! www.AJmonics.com
@@AJmonics definitely!
This video is just amazing!
Thank you so much Nasma! Worked so hard on that one!
This is amazing 👏
Thank you so much!
where is th 11?
This worths a million views
Thank you! Worked so hard on that video - I am happy it was worth it!
My favorite part was the parking
=) Amazed that you got that far
Oh my god. Love this
=) Thank you so much!! Working on a review card for it - will be available on my website. (Please check it out!! www.AJmonics.com/ )
thank you this is amazing
Thank you! So happy you liked it!
Very good
Thank you very much! Worked hard on that video!
WOW !!
Nice!
Thank you!!!
Nice
Thank you!
thanks lol super helpful
My pleasure! I spent soooo many hours on that one!
thank you
You are so welcome!! I hope you gain from it!
WHERE WERE YOU MY ENTIRE LIFE????
=) Happy to be a part of your life now!
Maddalo video na midday gudu
=)
Move over Hot T-Bone stEAK
=)
You rhyme a lot of times. Great starter content though bro
=) Thank you
THISSSSSSSSSSSSS
=) So happy you like it. Where are you from?
😂👍🏼
=) Thank you
LLLLLLLLLLLLLLOOOOOOOOOOOOOOOOOOOOOLLLLLLLLLLLLLLLLLLL TOOOOOOOOOOOO EASYYYYYYYYYYYYYYY
=) Thank you!!! So happy you liked it fellip!
U saved me 🫶🥹🥹
That's what I want to hear!