I have always been interested in the hypothesis of Evolution. I never thought to question the hypothesis until I started doing a lot of PC repair, mostly virus removal. I realized that a lot of people do not understand that computer viruses are created by human beings. Rather, they think they just appear out of nowhere. You might think they are stupid for thinking that, but from there point of view computer programmers don't even exist, so it kind of makes sense that they would think that. And when I would tell people that computer viruses are written by people, they always asked the same question, “Why would somebody do that?”
Great video! How many outbreaks would not exist if pigs, cows, chickens and other meats were not factory farmed or consumed by humanity? I wonder how many outbreaks come from fish? It seems a lot of the time the science isn't sure, but there are clues that the viruses came from animals. Meat consumption, of course, will never stop. Consuming wild animals is done for survival in many countries. It could be avoided or discouraged if done solely for pleasure.
I just realized why I basically never catch the flu. When I was a kid, I got a really bad H3N2 flu and several years later, I was really sick with an H1N1 flu. Of course, I am assuming based on the most prevalent strains of flu for those years that I got seriously ill. After getting sick with H1N1, I decided to believe my grandma that washing one's hands would make it less likely that one would get sick, even if the hands don't look or smell dirty. I haven't been seriously ill since then until COVID-19 showed up. I still get my flu shot every year because why even risk getting sick if there's a vaccine? I did have an allergic reaction to the flu vaccine grown in egg and the only reason I took that one instead of continuing to look for the egg-free version was that everyone in my family was already sick with the flu and I didn't want to get it. I did get Stevens-Johnson rash and I was itchy for about three days but it lasted less time than the flu infections my family had and I would take that rash any day before getting sick provided I had the proper antihistamines to treat the allergic reaction.
I see "selected/selection" as a huge mistake . . As few can separate the term from "purpose" . . A gauntlet, and an environmental challenge has escaped the general conception, whereby other "sins" slip in, such as saying, "the virus wants to do . . " Such and so . . Thanks for properly eliminating so many misconceptions.
I like "arms race" better than the Red Queen thing. Not many ppl outside of specific Western countries would know what that is. I'm sure many of the younger generation may not even know what Alice in Wonderland is.
Thanks for this wonderful course, I am hopeful your next lecture on 'Emerging Viruses' will mention perhaps some of the most significant impacts viruses have had on host populations that we know or can reasonably infer. Obviously, the 1918 flu pandemic was huge for humans but I am curious on what some other huge impacts might have been for humans and across species. Thanks again for this great work.
Hello: I heard you speaking in a recent Twiv about the mutation of the virus (and all viruses, of course). A recent paper came out and was shown in the news articles. Can you please comment on one of your shows that covers Coronavirus and relate it? For now I assume it is a media misrepretentation of facts, as is always wise. Quote: "The mutation Spike D614G is of urgent concern; it beganspreadingin Europe in early February, and when introduced to new regions it rapidly becomesthe dominant form" Article name and authors: Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2 KorberB1, FischerWM1, GnanakaranS1,YoonH1, TheilerJ1, AbfaltererW1, FoleyB1, Giorgi EE1, Bhattacharya T1,Parker MD3, Partridge DG4, Evans CM4, de Silva TI4,5, on behalf of the Sheffield COVID-19 Genomics Group#,LaBrancheCC2, and MontefioriDC2
You might find the link below interesting. It suggests that there are ultimately thermodynamic reasons for the generation of structure which natural selection can then act on. www.quantamagazine.org/a-new-thermodynamics-theory-of-the-origin-of-life-20140122/
Nothing needs to "drive" it, but simply, allow for it... a more complex things needs the less complex thing to exist first, to build upon... you need communities before you can have cities, but when you have communities, cities can be formed, giving you an increase in complexity. That process goes all the way down, through organised species, organised cells, organised molecules, all the way up through countries, empires, civilisations
Could the Australians infect rabbits with one virus, and then get rid of survivors by using another one, repeating the cycle for several years (and changing the virus species every time, of course)?
Dear Professor! I am sorry if I sound demanding I learn by writing notes on paper. Can I lay my hands on pdf of these educational lectures? One of the student of Virology.
RUclips somehow had me watch the 2019 version of this lecture first, one difference mutant swarms vs mutant clouds. When I think about the somewhat nondescript hosting of cloud computing programs, the term cloud seems more in line with your quasi term or i may just be confused.
Natural Selection is a real repeatable process. Evolution is just a hypothesis. Variations are NOT mutations, for example influenza does not mutate, it can produce a fixed number of variations through the process of reassortment. Most of the time when people say mutation they really mean variation. What's the difference, a variation is part of the design, it is per-programmed and produces a viable product. Mutations are never good, and always produce a defective product. Just like randomly messing with software code never produces a new feature, it just produce a defective product. However a computer virus can be designed to create variations of its self in order to trick your anti-virus, and from an outsiders prospective, you might think it is evolving, mutating, or adapting. But in reality those variations were per-programmed.
Don't talk nonsense Most mutations neutral the other part of the mutation is harmful or beneficial.Harmful mutations are rejected by natural selection and benefical ones are fixed .Many beneficial gene variants have been studied: The CKR5 gene produces a protein that specifies which compounds can enter the cell. An allele produced by deleting a single nucleotide in the CKR5 gene results in resistance to HIV (Dean et al. 1996). A point mutation in the LPR5 gene results in increased bone density, which is highly adaptive in an environment with a high expectation of injury (Boyden et al. 2002). The HbS gene that causes the harmful trait of sickle cell anemia also provides some advantage in providing resistance to malaria disease (a selective advantage in some environments).
For a biologist one of best things on the internet.
I am deeply grateful for all these information that you have taught.
Evolution is one of my favorite subjects. Great video!
I have always been interested in the hypothesis of Evolution. I never thought to question the hypothesis until I started doing a lot of PC repair, mostly virus removal. I realized that a lot of people do not understand that computer viruses are created by human beings. Rather, they think they just appear out of nowhere. You might think they are stupid for thinking that, but from there point of view computer programmers don't even exist, so it kind of makes sense that they would think that. And when I would tell people that computer viruses are written by people, they always asked the same question, “Why would somebody do that?”
I more than appreciate we are priviledged to see these more than informative lectures
Great video! How many outbreaks would not exist if pigs, cows, chickens and other meats were not factory farmed or consumed by humanity? I wonder how many outbreaks come from fish? It seems a lot of the time the science isn't sure, but there are clues that the viruses came from animals. Meat consumption, of course, will never stop. Consuming wild animals is done for survival in many countries. It could be avoided or discouraged if done solely for pleasure.
Thank you for being a teacher
I just realized why I basically never catch the flu. When I was a kid, I got a really bad H3N2 flu and several years later, I was really sick with an H1N1 flu. Of course, I am assuming based on the most prevalent strains of flu for those years that I got seriously ill. After getting sick with H1N1, I decided to believe my grandma that washing one's hands would make it less likely that one would get sick, even if the hands don't look or smell dirty. I haven't been seriously ill since then until COVID-19 showed up. I still get my flu shot every year because why even risk getting sick if there's a vaccine? I did have an allergic reaction to the flu vaccine grown in egg and the only reason I took that one instead of continuing to look for the egg-free version was that everyone in my family was already sick with the flu and I didn't want to get it. I did get Stevens-Johnson rash and I was itchy for about three days but it lasted less time than the flu infections my family had and I would take that rash any day before getting sick provided I had the proper antihistamines to treat the allergic reaction.
this lecture is awesome- helps lots to decode the current pandemic - thank you so much - great job
This lecture is especially interesting, extremely 👍👍👍
How many examples have transpired in which epidemical virus vary TOWARDS greater virulence vs AWAY from greater virulence?
I see "selected/selection" as a huge mistake . . As few can separate the term from "purpose" . . A gauntlet, and an environmental challenge has escaped the general conception, whereby other "sins" slip in, such as saying, "the virus wants to do . . " Such and so . . Thanks for properly eliminating so many misconceptions.
All very important
great explanation
Good one,
&thanks for making us laugh in these grim times (lifestyle comment :D)
Love the tattoo idea.
I like "arms race" better than the Red Queen thing. Not many ppl outside of specific Western countries would know what that is. I'm sure many of the younger generation may not even know what Alice in Wonderland is.
Thanks for this wonderful course, I am hopeful your next lecture on 'Emerging Viruses' will mention perhaps some of the most significant impacts viruses have had on host populations that we know or can reasonably infer. Obviously, the 1918 flu pandemic was huge for humans but I am curious on what some other huge impacts might have been for humans and across species. Thanks again for this great work.
thank you very much you are great
Hello: I heard you speaking in a recent Twiv about the mutation of the virus (and all viruses, of course). A recent paper came out and was shown in the news articles. Can you please comment on one of your shows that covers Coronavirus and relate it? For now I assume it is a media misrepretentation of facts, as is always wise.
Quote: "The mutation Spike D614G is of urgent concern; it beganspreadingin Europe in early February, and when introduced to new regions it rapidly becomesthe dominant form"
Article name and authors:
Spike mutation pipeline reveals the emergence of a more transmissible form of SARS-CoV-2
KorberB1, FischerWM1, GnanakaranS1,YoonH1, TheilerJ1, AbfaltererW1, FoleyB1, Giorgi EE1, Bhattacharya T1,Parker MD3, Partridge DG4, Evans CM4, de Silva TI4,5, on behalf of the Sheffield COVID-19 Genomics Group#,LaBrancheCC2, and MontefioriDC2
What drives the increasing complexity? Not today but in the beginning?
You might find the link below interesting. It suggests that there are ultimately thermodynamic reasons for the generation of structure which natural selection can then act on.
www.quantamagazine.org/a-new-thermodynamics-theory-of-the-origin-of-life-20140122/
Nothing needs to "drive" it, but simply, allow for it... a more complex things needs the less complex thing to exist first, to build upon... you need communities before you can have cities, but when you have communities, cities can be formed, giving you an increase in complexity. That process goes all the way down, through organised species, organised cells, organised molecules, all the way up through countries, empires, civilisations
Could the Australians infect rabbits with one virus, and then get rid of survivors by using another one, repeating the cycle for several years (and changing the virus species every time, of course)?
Perfect👍
Dear Professor! I am sorry if I sound demanding I learn by writing notes on paper. Can I lay my hands on pdf of these educational lectures? One of the student of Virology.
He has a book ... I looked into that awhile back.
www.virology.ws/course/
Great!
RUclips somehow had me watch the 2019 version of this lecture first, one difference mutant swarms vs mutant clouds. When I think about the somewhat nondescript hosting of cloud computing programs, the term cloud seems more in line with your quasi term or i may just be confused.
NEW VIRUSES what about the ones that come from outer space?
Imaginary viruses?
Um.. does anyone else think trying to wipe out rabbits with the Andromeda Strain doesn’t seem like a good idea?
Just when I think, "Oh this lecture won't be as interesting..."
This shit is fascinating.
Like saying earth is rotation
Free?????
Came to find out if it came from a lab lol
Check an Alex Jones video ...
/sarc
uploadJ if only it was just Alex Jones
Natural Selection is a real repeatable process. Evolution is just a hypothesis.
Variations are NOT mutations, for example influenza does not mutate, it can produce a fixed number of variations through the process of reassortment. Most of the time when people say mutation they really mean variation. What's the difference, a variation is part of the design, it is per-programmed and produces a viable product.
Mutations are never good, and always produce a defective product. Just like randomly messing with software code never produces a new feature, it just produce a defective product. However a computer virus can be designed to create variations of its self in order to trick your anti-virus, and from an outsiders prospective, you might think it is evolving, mutating, or adapting. But in reality those variations were per-programmed.
Don't talk nonsense Most mutations neutral the other part of the mutation is harmful or beneficial.Harmful mutations are rejected by natural selection and benefical ones are fixed .Many beneficial gene variants have been studied:
The CKR5 gene produces a protein that specifies which compounds can enter the cell. An allele produced by deleting a single nucleotide in the CKR5 gene results in resistance to HIV (Dean et al. 1996).
A point mutation in the LPR5 gene results in increased bone density, which is highly adaptive in an environment with a high expectation of injury (Boyden et al. 2002).
The HbS gene that causes the harmful trait of sickle cell anemia also provides some advantage in providing resistance to malaria disease (a selective advantage in some environments).