Chronic Myeloid Leukemia (CML) - Myeloproliferative Neoplasm (MPN) - Philadelphia Chromosome

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  • Опубликовано: 1 фев 2025

Комментарии • 557

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  3 года назад +7

    💊🦠 Antibiotics Course: www.medicosisperfectionalis.com/
    🧠 Autonomic Pharmacology Course: www.medicosisperfectionalis.com/

  • @user-mm6ii3yh9w
    @user-mm6ii3yh9w Год назад +53

    I don’t even know why I pay tuition anymore. Your videos are a life saver and it feels like with every topic I’ve had to learn in med school, you have a video on it! Incredible work. A generation of doctors is gonna owe you big time!

  • @ifrahakbar2878
    @ifrahakbar2878 4 года назад +212

    Just let me be rich man. I'll compensate for EVERYTHING. You are literally a life saver! Thank you for making these highly interactive and hilarious videos! You're John Cena of the medicine world i.e. you're the champ! Great work!

  • @yazannouh3897
    @yazannouh3897 4 года назад +41

    Dude i have no words to express how grateful i am to finding your channel , your lectures are absolutely remarkable , they are very simple and full of important information and i've been struggling with hematology a lot during my 4th year of medical education but since i found your channel it became so much easier for me with the way you introduce the information and explain it . thank you so much and god bless you .

  • @faisalbadsha
    @faisalbadsha 2 года назад +11

    I think your Haematology lectures are the most comprehensive, excellent and amazing videos as compared to other Haematology videos in RUclips. I am big fan of your videos. I am preparing my mrcp exams by your awesome lectures. 👌

  • @RustleInThaBush
    @RustleInThaBush 3 года назад +13

    Thank you! I got diagnosed with CML about a month ago and this genuinly helped me further understand what has been happening in my own body.

    • @jad3ruby_
      @jad3ruby_ 3 года назад +2

      So sorry to hear that, I hope things get better!

    • @itsqueenbeautiess9552
      @itsqueenbeautiess9552 3 года назад

      Hope you are doing well

    • @srimathikaja2844
      @srimathikaja2844 2 года назад +1

      stay strong ! sending you all love and prayers :)

    • @slyth3rinprincess
      @slyth3rinprincess 2 года назад +1

      same but mine was almost for 6 years now.

    • @julielea8344
      @julielea8344 2 года назад

      Can you tell me any other symptoms other than weight loss & exhaustion?

  • @swapnilsingh2808
    @swapnilsingh2808 6 лет назад +71

    Soon to be a Great channel on medicine!! You are at osmosis and dr.najeeb level and these videos are greatest help to me in hematology! Keep up the great work!!#Fan

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 лет назад +4

      I can’t thank you enough! Appreciate it!

    • @sumbalijaz3551
      @sumbalijaz3551 6 лет назад +15

      @@MedicosisPerfectionalis In fact better than osmosis :)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 лет назад +5

      Thank you very much 😊

    • @Besho320
      @Besho320 6 лет назад +4

      Yess, osmosis was the best for me . But now I am stalking all the time with your channel. You are the best❤️❤️❤️❤️

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 лет назад +4

      What an honor! I can’t believe what I am reading...I am absolutely thankful!

  • @nitinsingh7827
    @nitinsingh7827 6 лет назад +26

    i am docter i saw ur video ...your video awesome for medical student ...good work keep it up....

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 лет назад +1

      Thanks, doctor...I sure will!

    • @nitinsingh7827
      @nitinsingh7827 4 года назад

      @@ricasaluria8821 Pls explain miss Rica.. I am not understand.. Meaning

    • @nitinsingh7827
      @nitinsingh7827 4 года назад +2

      @@ricasaluria8821 oh thnx my mistake 😅😅😅

    • @ricasaluria8821
      @ricasaluria8821 4 года назад

      To be fare if you're a doctor you have more knowledge than me regarding medical terminology. ✌️ It's only one letter 😉

    • @nitinsingh7827
      @nitinsingh7827 4 года назад +2

      @@ricasaluria8821 yes this is true that at least me.. Have correct knowledge about medical terminology.. Thank I admire of your fine eyes ☺☺☺

  • @alinausman9409
    @alinausman9409 3 года назад +2

    I got to know about this channel. I told my friends. I told my class. I told my whole batch about this incredible treasure i found.. Now it will be passed to our junior class. They will also do the same.. Ahhh now these videos will be a part of our medical life

  • @wickkk1
    @wickkk1 Год назад +1

    you explain alot better than 99% of any doctor teacher i ever had

  • @mariefardova9958
    @mariefardova9958 7 месяцев назад +2

    I am an ET patient with prefibrotic stage in bone marrow yet. Your videos are the only ones, that help my understand the whole context of my disease. Thanks a lot.

  • @ahmadaljazeeri9287
    @ahmadaljazeeri9287 4 года назад +7

    I am so happy I watched 100 videos of this haematology playlist and probably another 100 videos of other lists in your channel 😍
    I cannot imagine the effort and time you put in making these videos! Wow you’re impressive!!!
    I am very grateful and thanks a lot!
    I will continue watching your videos and hopefully watch them all. I hope you always accept me as your student 😇

  • @dingdong436.
    @dingdong436. 2 года назад +4

    Superb Medicosis! Content went straight to the memory because of the way you present! Thank you very much!❤❤

  • @nehasaleem4718
    @nehasaleem4718 2 года назад +1

    Thank goodness for you🙏🏻🙏🏻🙏🏻🙏🏻It took me one day to read through 50 pages of Davidson only because I had all the important concepts through your video😭😭ilysm life save!

  • @EfrahNaz
    @EfrahNaz 2 года назад +1

    Thankyew medicosis...I recommended ur lectures to my class fellow who was struggling to understand Vitamins and now she is your fan..:)

  • @drrubaiyanishat5322
    @drrubaiyanishat5322 3 года назад +8

    You have made leukemias and lymphomas so easy, I found these topics very difficult earlier. Thanks a lot doc

  • @aspenmiller1454
    @aspenmiller1454 4 года назад +2

    Thank you so much for making these videos. I can't thank you enough honestly. I have been trying to find thorough videos that keep my attention and I finally have. You are great at explaining plus you add a little humor here and there. I have no idea why I laughed so hard at "mommy" and "daddy". :) Seriously thank you for your work! You truly have a way of reminding me why I chose the medical field in the first place. After years of schooling its easy to lose sight of my passion. THANK YOU!

  • @JJ-bl5wo
    @JJ-bl5wo 5 лет назад +19

    Really helpful, understandable and interesting... I love your enthusiasm and sarcasm😂😂 I don't know if I should be laughing and smiling;enjoying studying pathology!😄❤

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +1

      😅😂😁 The pleasure is mine!

    • @julielea8344
      @julielea8344 2 года назад +1

      I'm here because I'm sick, & I love his personality, he actually throws in a bit of empathy, even if slightly sarcastic at times it's sooo much better than other channels!! I wish all Drs were the same!

  • @precious3844
    @precious3844 5 лет назад +1

    A certain CEO of a very big company in my country died yesterday and he had this type of cancer. This is first time to see your channel thanks for explaining this I had no idea of this type of cancer. Love from East Africa

  • @dr.sananesar958
    @dr.sananesar958 5 лет назад +5

    Each time i see ur videos, i get more n more clarity in my head☺☺.. What an explanation.. Crystal clear.. Thank u soo much😘😘😘.. Plz keep making such videos.. And congrats for ur new microphone 😃🎊

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +2

      Thanks a lot...You l have a great ear and a kind heart ❤️...Please share my videos with others, it really helps me!

    • @dr.sananesar958
      @dr.sananesar958 5 лет назад

      @@MedicosisPerfectionalisyeah sure.. Definitely I m going to share it with my colleagues.., ☺

  • @snehajpraj9100
    @snehajpraj9100 6 лет назад +2

    Thank you so much...You reduced a lot of byhearting stuff because I understood the concept. Byhearting is very scary cause you won't know when you will forget it, but once you understand something you will remember it forever. May GOOD GOD bless you.

  • @Clauudiiiiia
    @Clauudiiiiia 6 лет назад +79

    'Hello, it's cancer', 'are these cells do their job properly or do they suck'🤣 haha. Thank you so much for these videos!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  6 лет назад +1

      You’re very welcome! Best of luck to you! Thanks a million for your comment!

    • @Mitzoo
      @Mitzoo 5 лет назад

      quite a lot of needy romanian med students in here

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад

      What do you mean by “needy”? 🤔

    • @Mitzoo
      @Mitzoo 5 лет назад +1

      @@MedicosisPerfectionalis we are lacking logical explanation... That's what I mean by "needy" 😂
      P.s: thank you a lot for the uploads, great work!

  • @dr.resmisumesh4512
    @dr.resmisumesh4512 6 дней назад

    Such a good channel.....really helpful.seen many you tube videos.urs is amazing.

  • @MountainMST
    @MountainMST 2 года назад +1

    Great video describing all the scientific breakdown of CML. I was diagnosed with CML in 2019. I have found that benzene exposures can also be a factor in the likelihood of this cancer forming.

  • @reineamare2460
    @reineamare2460 Год назад +1

    Thanks!

  • @rumesa9947
    @rumesa9947 3 месяца назад

    Thankyou so much. I have exams tomorrow and this was a huge help!!

  • @shakiraziz853
    @shakiraziz853 3 года назад

    Very comprehensive and detailed explanation. I am learning my brother who just recently suspected with CML.. thank you very much, this is very helpful!

  • @meme-lm2zd
    @meme-lm2zd 6 лет назад +2

    I'm about to end all the videos of this fascinating series..
    n by the end I'm not the same person who entered it..u've lightened me up..thanx alot doctor.. keep it up

  • @alexandramandea9867
    @alexandramandea9867 4 года назад +2

    Too bad they don`t explain that well in medschool. You make medschool students` lives easier. Thank you!

  • @6474323
    @6474323 2 года назад +1

    I couldn't resist but to comment ... i love your videos man .. once i have credit i will definitely support your channel ...

  • @shaheensalamat9929
    @shaheensalamat9929 4 года назад +2

    Your way of teaching is amazing, it made the topic sooo easy. Thank you for this wonderful video😄😄

  • @Livingthewayiwant
    @Livingthewayiwant 4 года назад +1

    what a crystal clear explanation... not complicated also.... love your videos.. keep it coming

  • @tiktokhub4298
    @tiktokhub4298 2 года назад

    mark my words bro i owe you a million dollars for this video

  • @dianebautista6030
    @dianebautista6030 6 лет назад +4

    this is an awesome video! Thank you for this! Hoping for more episode! You really have the potential, dude! I love it

  • @mahirahmariam
    @mahirahmariam 5 лет назад +3

    Thank you so much for all these videos. I just discovered your channel couple of days back and your videos have been really really helpful. 😊

  • @busranurbozkurt
    @busranurbozkurt 2 года назад +1

    You are a lifesaver🥺 Thanks🙏

  • @MohammadAldefrawy
    @MohammadAldefrawy 2 года назад +2

    مجهود رائع يا صديقي ... شكرا لك على تسهيل المعلومات وتقديمها سائغة للمتابعين

  • @arjackson8036
    @arjackson8036 2 года назад

    Awesome videos! Some other sources say there is a percentage of patients with CML who do not have the Philadelphia chromosome. 5-10%

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  5 лет назад +11

    Sorry! I made a MISTAKE in this video!
    The mistake: CML is characterized by increased number of neutrophils.
    The correction: CML is characterized by increased number of basophils.
    💊 👨‍🏫 Antibiotics Lectures: www.medicosisperfectionalis.com/products/courses/antibiotics/
    💉 📜 My Notes, cases and courses www.medicosisperfectionalis.com/
    😅 If you like mnemonics, try Picmonic: www.picmonic.com/referrals/JK55NQXQQB9JLC119
    📕📗 Books that I recommend, www.amazon.com/shop/medicosisperfectionalis

    • @emilysouther4614
      @emilysouther4614 5 лет назад

      I had a flow cytometry that came back negative but I tested positive for the Philadelphia (bcr-abl) now I'm going for a bone marrow biopsy. Could I have CML

    • @emilysouther4614
      @emilysouther4614 5 лет назад

      Also I was diagnosed with absolute lymphocytosis

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +2

      Could be...Only the biopsy can confirm...Please don’t panic...Stay calm and wait for the results...We don’t know anything yet, it could be false positive, and even if it’s CML, it’s very treatable...Your emotional stability is really important, so please take it easy, and follow up with your doctor...If you have any questions, let me know...and keep me updated...All the best!

    • @emilysouther4614
      @emilysouther4614 5 лет назад

      @@MedicosisPerfectionalis have you heard of negative flow cytometry and positive for the bcr-abl? I love all your videos. I'm not a medical professional but I love everything about it. I'm actually doing a lot better than everyone else around me. Ive done a lot of research and am super positive.

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +1

      FISH is more accurate than flow cytometry, but the biopsy is the most accurate. Thanks...Keep it up.

  • @tamaradimes4438
    @tamaradimes4438 3 года назад

    these videos helped me alooottt to get through my HLS system thank you so much all the way from Jordan

  • @lisamalipilo5113
    @lisamalipilo5113 2 года назад +1

    You saved my degree 💯

  • @cgh148
    @cgh148 Год назад +1

    I was diagnosed with CML at the age of 19. 27 now. I had around 850 WBC on my CBC when I was first admitted to the hospital. I also lost my hearing due to the amount of WBC. Crazy thing was I was still some how in the Chronic phase. Additionally, my brain was swelling to the point it was touching the cranium, my heart was swelling as well. Of course my spleen was huge. A bunch of other wild symptoms occurred as well. Looking back I should have gone to emergency way earlier.

  • @garrett_jp
    @garrett_jp 3 года назад +1

    I really appreciate every one of your videos -- couldn't get through heme / lymph in med school without you. Thank you!

  • @JPlay777
    @JPlay777 5 лет назад +5

    Hello. Thank you for making these videos. They are really well done. I am wondering if you have done, or are planning on doing a video on CMML. All the best to you!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  5 лет назад +1

      Thanks for your question...Can you please send me a message on my Facebook page?

  • @Mariah-ge5be
    @Mariah-ge5be 6 лет назад +2

    I can't thank you enough for these useful and full of inforamtion videos!🤩💙this is inspite of the understandable explanation of the subject itself👏👏

  • @rukiee.b.ovwigho5709
    @rukiee.b.ovwigho5709 2 года назад +2

    Thanks for your well-explained, easy video. You're making medicine fun and easy 👏👏👏

  • @SH-my4bd
    @SH-my4bd 3 года назад +1

    You’re so cute 🥺 the mic thing made me say awwww🥺♥️♥️♥️

  • @افنانمحمد-ي6ص
    @افنانمحمد-ي6ص Год назад +1

    You are a serious legend 🍀

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  Год назад +2

    📝 Download my handwritten notes: www.medicosisperfectionalis.com/

  • @christfollower5713
    @christfollower5713 4 года назад +2

    Oh i find this better than Osmosis , real human voice with very good speed level in your speech , thanks man , Jesus bless you ❤

  • @olamideoludoju
    @olamideoludoju Год назад +1

    God bless you medicosis for interesting haematology videos 🤩

  • @misthisinha3157
    @misthisinha3157 2 года назад +1

    Your explanation is very good. Thanks 😊

  • @veggiechefCD
    @veggiechefCD 6 лет назад +3

    Very good video.. among the best I have watched after a CML diagnosis..

  • @anmolsamanta2873
    @anmolsamanta2873 4 года назад +1

    Ur videos make concepts so easy and fun... Love ur videos

  • @asmaoushi3564
    @asmaoushi3564 9 месяцев назад +1

    🎉 no word can explain my gratefulness, just we r thankfull beyond the infinity

  • @sushmasepta8704
    @sushmasepta8704 Год назад

    U r great brother
    U helped me to clear interventional cardiology entrence

  • @RAN-mh7fx
    @RAN-mh7fx Год назад +1

    This was really helpful. I’m in love with your videos

  • @amritajyoti2176
    @amritajyoti2176 2 года назад

    You made hematology intersting for me! Hats off!✨🍀✨

  • @Kpimoli77
    @Kpimoli77 5 лет назад +6

    Blessing as a human!

  • @asmitapokharel5847
    @asmitapokharel5847 5 лет назад +1

    You are the best teacher . Thank you for all the amazing video😌

  • @khalidsaeedt.v9637
    @khalidsaeedt.v9637 Год назад

    best lectures for medical students

  • @loyaltyesmaeel5656
    @loyaltyesmaeel5656 6 лет назад +1

    excellent work 👏👏👏
    but plz add to the video the new classification of myeloid neoplasm by WHO 2016 because acc to this classification blast cell in CML up to 19% and many other items to diagnose CML by blood film and no need for BM examinations to diagnose CML and at 11:30 plz explain more the cell lysis syndrome
    thank you 🙏 for the great video sooon you will be no 1 medical channel 👏👏👏🤗🤗🤗

  • @DoctorAmritPandey
    @DoctorAmritPandey Год назад +2

    Thank you very much. Keep making such awesome videos 😊

  • @shahinvasigh1889
    @shahinvasigh1889 Год назад

    Very simple and useful explanation great job❤

  • @thankusimon5451
    @thankusimon5451 2 года назад

    Thankyou So much for your information, extreamly thankfull to you , i was also diagnosed cml 37% in bcr test and taking imatinib 400 veenat since 3 month , going to test again next month, no other problems yet, only some times feeling cold in normal wheather and Hemoglobin stays 10.5 not moving up

  • @leonardopeixoto5162
    @leonardopeixoto5162 5 лет назад +1

    Just figure it out your channel and I'm loving it!

  • @EdisonBrewster
    @EdisonBrewster 5 лет назад +1

    Finally! I can understand what the hell happens to me. Extremely helpful, it's not easy to recieve all this info from an oncologist face to face. Thanks so much for this awesome presentation.

  • @margaridaeumeggy887
    @margaridaeumeggy887 Год назад +1

    so good, thx ill pass my exams bc of u :)

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  Год назад +1

      I am honored, Margarida!
      I wish you all the success in the world!
      When you have a moment, would you please help me by sharing?

    • @margaridaeumeggy887
      @margaridaeumeggy887 Год назад

      @@MedicosisPerfectionalis im going to share with all my peers

  • @shahdebied8586
    @shahdebied8586 3 года назад +2

    You saved my life !❤️

  • @archanamohan.v2320
    @archanamohan.v2320 4 года назад +1

    You are best teacher sir😊❤️

  • @rojinmansouri9452
    @rojinmansouri9452 7 месяцев назад +1

    Thank you 😍😍

  • @blueblah620
    @blueblah620 3 года назад +1

    Suchh an amazing work .really addicted for your videos great medicosis

  • @مروةالبشير-ب6ط
    @مروةالبشير-ب6ط 3 года назад

    This is sooo crazy 😭🖤
    I spent more than 2 weeke try to undestand leukemia... And i feel satistid just after 2 minut from starting veidio 😭🖤

  • @MedicosisPerfectionalis
    @MedicosisPerfectionalis  4 года назад +7

    😍🖼Animated Mnemonics (Picmonic): www.picmonic.com/viphookup/medicosis/
    📗 Get my notes in pdf files at www.medicosisperfectionalis.com/
    If you like my videos, please consider leaving a tip at www.paypal.me/perfectionalis/

    • @gegeehab9176
      @gegeehab9176 4 года назад

      الشرح بتاعك احسن منهم الف مره..دول داخلين مسابقه ف سرعه الكلام

  • @amalaldakhil03
    @amalaldakhil03 Год назад

    Loved your explanation. It was very informative.

  • @Mim2nord
    @Mim2nord 3 года назад

    I think you'd better say "THERE's a high LAP" , instead of "YOU have a high LAP".
    Thank you for your videos, you are helping us greatly..

  • @مروةالبشير-ب6ط
    @مروةالبشير-ب6ط 3 года назад

    Oh man
    Should you upload your notes in this video 🖤
    It will be greater than any textbook 😭🖤

  • @joz4448
    @joz4448 3 года назад +1

    Your videos are awesome, greatly appreciated !!!

  • @afshan2089
    @afshan2089 Год назад +1

    Your videos are very helpful.Thank you very much.

  • @carolinasalazar5019
    @carolinasalazar5019 2 года назад

    i don’t understand why there is an anemia since this is a myeloproliferative neoplasia, the number of erythrocytes shouldn’t be raised?
    thank you so much for this!

  • @raviShankar-sm1nj
    @raviShankar-sm1nj 3 года назад +1

    Lots and tons of respect for u...

  • @elahdiamante7355
    @elahdiamante7355 5 лет назад +2

    it is really helpful for my coming exam . thank u medicosis perfectionalis!!! God bless

  • @AhmedKareem1996
    @AhmedKareem1996 5 лет назад

    Thank you for the great info.
    Note : BCR is (Breakpoint Cluster Region) not Break Cluster Region 4:23

  • @hebahammoudi7160
    @hebahammoudi7160 18 дней назад

    You are a legend

  • @maryamalrawi6645
    @maryamalrawi6645 4 года назад +1

    Really you are greatest one 😍👏👏👏👏

  • @priyasharma1110
    @priyasharma1110 5 лет назад +1

    Excellent explanation 😊☺

  • @romer2279
    @romer2279 4 года назад

    thanks for sharing.. im dealing with CML since 2015..

  • @vijaybylla9541
    @vijaybylla9541 4 года назад

    Wise and wonderfulll
    Too much dazzled in the way u TEACH
    THANK YOUU👍

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  4 года назад +1

      Thank you 🙏

    • @vijaybylla9541
      @vijaybylla9541 4 года назад

      Didnt know it should be this much fun until u teach😍😍tqq
      Keep making vds
      We r in love with them 💛

  • @jacksparrow-wq1pb
    @jacksparrow-wq1pb 11 месяцев назад

    Love your lessons ❤❤❤

  • @nirsamra9016
    @nirsamra9016 6 месяцев назад

    really good and informative video thank you !! , can you refer or tell me why in cml there is increast in b12 ?

  • @graciacharliemushinye9511
    @graciacharliemushinye9511 2 года назад

    Thank you medicosis!

  • @noularahim
    @noularahim 2 года назад

    Wow what an explanation !

  • @tpkgmc1391
    @tpkgmc1391 4 года назад +1

    Your video is more than brilliant,, keep it 👆

  • @ReznickovaJ
    @ReznickovaJ 3 года назад

    I love how you talk to me like Im stupid. Beause I am. Thank you for the videos!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      You’re not stupid!
      I was just trying not to make the lectures boring 😊

    • @ReznickovaJ
      @ReznickovaJ 3 года назад

      @@MedicosisPerfectionalis haha, It was just a litttle diss at myself :D The videos are great and help a lot!

    • @MedicosisPerfectionalis
      @MedicosisPerfectionalis  3 года назад

      Thank you 🙏

  • @dinimutiakhairunnisa4439
    @dinimutiakhairunnisa4439 3 месяца назад +1

    thankyou😍

  • @sidharthramdas427
    @sidharthramdas427 5 лет назад +1

    Really understood the concept of CML..thank you so much for this video..you are doing an amazing job.🙏❤️

  • @esrailsk4592
    @esrailsk4592 5 лет назад +1

    Your video is just amazing...👌👌👌

  • @سوسوسو-ض3ن
    @سوسوسو-ض3ن 4 года назад +1

    thank you so much for all this

  • @dahis6763
    @dahis6763 10 месяцев назад

    I love your explanation

  • @dibyasattwakarmakar
    @dibyasattwakarmakar Год назад +1

    Thank You , Sir