Oncology Horizons: New Prospects and Targets for Pediatric and Adult Brain Cancer Intervention

Drs. Sheila Singh and Hong Han from McMaster University. They will be presenting their work on understanding cancer stem cells and the cancer stem niche in the initiation of brain tumours and resistance to therapy as well as systems biology approaches to identify new molecular drivers and therapy targets in the tumour microenvironment.
Targeting clonal heterogeneity in treatment-refractory Glioblastoma with novel and empiric immunotherapies
Dr. Sheila Singh
Dr. Sheila Singh is a Professor of Surgery and Biochemistry, Chief Pediatric Neurosurgeon at McMaster Children’s Hospital, the Division Head of Neurosurgery at Hamilton Health Sciences, and the inaugural Director of McMaster’s new Centre for Discovery in Cancer Research. She holds a Tier 1/ Senior Canada Research Chair in Human Brain Cancer Stem Cell Biology and is Director of the McMaster Surgeon Scientist Program.
Embracing complexity to achieve precision: multilayer cell fate control in brain development and cancer
Dr. Hong Han
Dr. Hong Han received her B.Sc. Honours degree at the University of British Columbia and then completed her Ph.D. in the Department of Molecular Genetics at the University of Toronto (U of T). Dr. Hong was the first recipient of the prestigious Donnelly Home Research Fellow Fund at U of T, which allowed her to become a semi-independent investigator to develop projects and supervise a research team. In 2022, she was appointed as an Assistant Professor in the Department of Biochemistry and Biomedical Sciences and a Principal Investigator at the Centre for Discovery in Cancer Research at McMaster University.