Bilirubin

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  • Опубликовано: 8 фев 2025
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Комментарии • 114

  • @Jerry-dv1gy
    @Jerry-dv1gy 2 года назад +113

    I think I speak for thousands of people when I say that I'd pay major $$$ for a Pathoma/Boards/Osmosis/Physeo type service made by you. Blessings my guy

  • @nahidahrahman3939
    @nahidahrahman3939 4 года назад +224

    its cute how Dr. Dirty Medicine says he loves us at the end of each video

  • @adamgrobart8691
    @adamgrobart8691 3 года назад +12

    this video alone is worth $4.99. Thank you for making studying so much more enjoyable!

  • @nenimarie89
    @nenimarie89 4 года назад +26

    dirty.... simply love you. When I'm not a broke med student, I will make sure to donate any way I can!

  • @sidc1759
    @sidc1759 4 года назад +19

    Literally died laughing at the Rock has come back to dirty medicine 😂. Im friends with his first cousin haha we went to undergrad together

  • @amibenya
    @amibenya 4 года назад +23

    Another mnemonic about Dubin Johnson vs Rotor : in Dubin johnson liver is Dark, in Rotor it s Regular.

  • @innominadojustis2224
    @innominadojustis2224 3 года назад +5

    This is Pure Gold, to me you DESERVE NOBEL PRIZE, thank you for helping us and beeing you👍🏻

  • @urvimistry4069
    @urvimistry4069 2 года назад +6

    Your lectures are life savers for exams!!

  • @PS-pr5py
    @PS-pr5py 4 года назад +3

    Pay the man!!!!
    Awesome vid. Thank-you.

  • @akshayakannan9959
    @akshayakannan9959 4 года назад +8

    Best video I've seen on the topic! 🙌 Thank you so much, you're great!

  • @footballsgreatest2645
    @footballsgreatest2645 4 года назад +11

    Excellent video as always. Would be great if you could do a video or two on Hepatitis if possible
    Congrats on making the First Aid list again!

  • @Ziakhan-km9du
    @Ziakhan-km9du 4 года назад +7

    Waoooooooo amazing sir most of time I recommended your vid in diff step 1 preparation grp

  • @meenabarot2037
    @meenabarot2037 Год назад +1

    you are the best Doc!!

  • @ggockma20
    @ggockma20 3 года назад +1

    This was great, Dirty you are the people’s Champ!

  • @johnkevin1104
    @johnkevin1104 2 года назад +1

    i didn't expect to see the Rock in a video about bilirubin, i am pleasantly surprised

  • @alih6953
    @alih6953 4 года назад +2

    Glad to see you back amazing work as always brother!

  • @alih6953
    @alih6953 Год назад +1

    You explained this better than Pathoma! You rock!

  • @hyperduke26
    @hyperduke26 2 года назад +2

    You're too AWESOME, please be a professor and your students will love you.

  • @KkIaRvAyNa
    @KkIaRvAyNa 6 месяцев назад

    For rotor syndrome, mneumonic is ROlled OATs, and oats are "not black" in colour, so is the liver in Rotor Syndrome

  • @animalloverb15
    @animalloverb15 4 года назад +4

    boards in 2 weeks and this is one of my weaker areas, thanks!!

  • @thehandlez
    @thehandlez 3 года назад +1

    For Dubin-Johnson think of the MR(C)P in Dublin

  • @obinnaokolocha4462
    @obinnaokolocha4462 3 года назад

    I have always used the Rock to remember Dubin Johnson.. I was so happy to see this

  • @l2ebel96
    @l2ebel96 4 года назад +1

    Great tie-in with Dubin Johnson and honestly one of the greatest WWE superstars.

  • @AKAzad-cd4jp
    @AKAzad-cd4jp 5 месяцев назад

    i just love this channel , awesome

  • @klosero448
    @klosero448 4 года назад

    the people elbow haha nice mimo about the rock :) you rocking bro

  • @100.shivasankarsubramanian9
    @100.shivasankarsubramanian9 Год назад +1

    Dubin Johnson ( Dwayne Johnson )
    Black liver ( black Adam )

  • @aliozochika3702
    @aliozochika3702 Месяц назад

    If only I had money I would sponsor all these lectures

  • @ericao2014
    @ericao2014 4 года назад +1

    This is GOLD! Thank you so much!

  • @jakobjusinski
    @jakobjusinski 17 дней назад

    Thanks!

  • @musabzulfiqar
    @musabzulfiqar 3 года назад

    You've got a gift man, great video

  • @oliviabunbury7025
    @oliviabunbury7025 4 года назад +6

    Made my day when the Rock was mentioned 😌🙏🏽

  • @lcasey-bb8vz
    @lcasey-bb8vz 4 года назад +14

    Hey thanks so much for the video! I am slightly confused how we will be able to distinguish between gilbert syn and CJ2. If they both have decreased UDP glucuronyl transferace?

    • @dinabadawy32
      @dinabadawy32 4 года назад +37

      The age of onset is one way. CJ2 will be during neonate/infant stages while Gilbert will be older child/adolescence (since its usually asymptomatic for the most part until jaundice is triggered).
      Also, Gilbert usually triggers jaundice during stressful situations like fasting and with alcohol consumption.
      And one last thing, indirect bilirubin in CJ2 is usually < 20mg while in gilbert, its usually < 3mg.
      Hope this helps!

  • @madusatharasingha5841
    @madusatharasingha5841 Год назад

    Thank you. Great video ❤

  • @rampdtiwari1051
    @rampdtiwari1051 4 года назад +1

    U r great presenter

  • @OsvaldoVillarreal-zq4hs
    @OsvaldoVillarreal-zq4hs 8 месяцев назад

    Great Lecture

  • @Drsarakanna
    @Drsarakanna 2 года назад

    Fantastic explanation

  • @g.a.r3058
    @g.a.r3058 2 года назад

    appreciate the thing you do, thanks man

  • @42taranpreetsingh88
    @42taranpreetsingh88 11 месяцев назад

    HI! Can we get a video on git embryology? Would really appreciate the help. THANK YOU. Love the videos.

  • @imranulhoda1005
    @imranulhoda1005 4 года назад

    You are Simply Awesome Sir 👌

  • @aayushirajani8088
    @aayushirajani8088 4 года назад +1

    can you make videos on the esophageal diseases and or various liver problems like steatosis and alcoholic and hepatitis changes

  • @Lilisusmle
    @Lilisusmle 3 года назад

    u r the best ! thank you

  • @ahmedelnaggar8337
    @ahmedelnaggar8337 Год назад

    My UGTA1A is deficient according to my genetic test. But tests don’t show higher than normal indirect (unconjugated) bilirubin, but it’s the Conjugated that’s slightly high. My ultrasound shows nothing wrong with liver biliary ducts. I have beta thalassemia.

  • @fereshtahkhoshbakht1999
    @fereshtahkhoshbakht1999 4 года назад +1

    Very useful 👌

  • @sharikkhan4945
    @sharikkhan4945 23 дня назад

    Great way of explanation.. btw whats difference between Gilbert and criglar najjar type 1..

    • @TheDannie17
      @TheDannie17 11 дней назад

      The main difference is the severity, Gilbert syndrome is a very mild form that can be asymptomatic or occasionally cause jaundice during stress, fasting, etc but otherwise doesn't require treatment, and Crigler-Najjar type 1 is a more moderate form that can manifest with symptoms and be treated with phenobarbital

  • @nicewoman2900
    @nicewoman2900 3 года назад

    Thank you very much😊😊

  • @isharaudanipuhulwella2716
    @isharaudanipuhulwella2716 2 года назад

    Great explanation 👍

  • @siddharthrahul99
    @siddharthrahul99 4 года назад

    U are awesome. Thanks bro

  • @jeremymoore145
    @jeremymoore145 2 года назад

    Thank you.

  • @kayallen7603
    @kayallen7603 Год назад

    Can they not be treated by introducing the needed enzyme?

  • @thepacemaker8165
    @thepacemaker8165 4 года назад

    Will definitely send in some help ....thank you

  • @Kat-tc3uy
    @Kat-tc3uy 3 года назад

    awesome!! more GI path please

  • @vanshajchandra307
    @vanshajchandra307 4 года назад

    Just 5 sec into your video and I click the Like button because I know I am gonna like it anyway Dr Dirty

  • @pedazodetorpedo
    @pedazodetorpedo Год назад

    My clue for Dubin-Johnson and the black liver is that Dubh means black in Irish and Gaelic, as in Dublin "Black Pool"

  • @deedhymaira2040
    @deedhymaira2040 Год назад

    Amazing 👏 ❤

  • @hallomer
    @hallomer Год назад

    Thankyou

  • @dailyusmle8710
    @dailyusmle8710 4 года назад +3

    Is the black liver primarily due to conjugated bilirubin buildup in the liver? Cause if both Dubin johnson and Rotor have an increased buildup of conjugated bilirubin then why doesnt the increased buildup cause the liver to appear black in Rotor?
    Can anyone answer this please....

    • @rachelbarnhill9808
      @rachelbarnhill9808 2 года назад +4

      I know this question was asked a year ago but just in case anyone else is wondering: DJ is a defect in getting conjugated bilirubin out of the hepatocytes and into the bile canaliculi. Rotor syndrome is a defect in getting recycled bilirubin back into the liver. So Rotor syndrome has an elevation in bilirubin outside of the liver = no black liver!

  • @xxaejon3217
    @xxaejon3217 Год назад

    may god bless u

  • @assholapure
    @assholapure 2 года назад

    We love you back 💕

  • @erikramos7206
    @erikramos7206 4 года назад

    Great man, great man!

  • @Kunosamah
    @Kunosamah 2 месяца назад

    Bro ur the goat indeed

  • @MaryamMahboob-u4c
    @MaryamMahboob-u4c 8 месяцев назад

    It really was an amazing lec

  • @piyooshverma6187
    @piyooshverma6187 4 года назад

    Amazing work ... Antiretroviral drugs please

  • @zaheerchoudhury3093
    @zaheerchoudhury3093 2 года назад

    Thank you sir💖

  • @島影ふじえ
    @島影ふじえ Год назад

    dirty how can i contribute without becoming a monthlo supportet?

  • @MuhammadAhsan-mp8hq
    @MuhammadAhsan-mp8hq 2 года назад

    How to differentiate Gilbert fro criggler 1

  • @kaitewalkermutale7038
    @kaitewalkermutale7038 3 года назад

    you are the best

  • @jagadishmrv
    @jagadishmrv 10 месяцев назад

    Amazing

  • @faridamcole5632
    @faridamcole5632 2 года назад

    Amazing thank you.

  • @zahhio8000
    @zahhio8000 2 года назад

    If there was udp-glucuronyl transferase deficiency does that mean there isn’t any conjugated bilirubin? Then how the body gets rid of the bilirubin?

  • @amaneehmeh8756
    @amaneehmeh8756 4 года назад

    dude you're so amazing . This was so helpful

  • @richarddarrah2014
    @richarddarrah2014 3 года назад

    I can smellllllllllllllll, what the Rock, is cooking in this video.

  • @pedazodetorpedo
    @pedazodetorpedo Год назад

    What would I have if presenting with isolated direct and indirect hyperbilirubinemia with 30% direct fraction? Total bilirubin level is 27 umol/L (normal range 0-20 umol/L)

  • @SalmaSafory
    @SalmaSafory 2 года назад

    Its amazing ✨✨✨✨ and i guess you need to change the title to congenital hyperbilirubinemia

  • @muzamilmehmood3195
    @muzamilmehmood3195 4 года назад

    An excellent lecture wd good meumonic.... But i m getting too much adds while watching it..

  • @ibrahimsaeed9366
    @ibrahimsaeed9366 Год назад

    Thanks man

  • @christinehuynh7642
    @christinehuynh7642 3 года назад

    I dont quite understand the difference between crigler najjar II and gilbert. is it just a different gene involved? Both decrease UDP Glucuronyl transferase and increase unconj bilirubin?

  • @tasniaferdous4569
    @tasniaferdous4569 Год назад

    THANK YOUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU!!!!!!!!!

  • @B3bita1215
    @B3bita1215 2 года назад +1

    I love you too Dirty 😭❤️

  • @alaabayoumy4853
    @alaabayoumy4853 2 года назад

    Heyy are there other videos for git other than these 4??? Please help thanks!!!

  • @muhammadjunaidali769
    @muhammadjunaidali769 4 года назад

    Awesome

  • @Sasukeloverxxx
    @Sasukeloverxxx 4 года назад

    This>>>UW explanations

  • @mohamedafifi955
    @mohamedafifi955 4 года назад

    You're amazing

  • @zeinshabarek5026
    @zeinshabarek5026 2 года назад

    thankuuuuuuuuuuuu

  • @tom301292
    @tom301292 4 года назад

    Great video, thanks! 4 or 5 adverts is a bit excessive and rather annoying though 😒

  • @aleksandarmisic6998
    @aleksandarmisic6998 3 года назад

    I have Gilbert. how my level bi,irybin go down or low.Somthing advice ,cure Can help with Calcium d clucarate

  • @jaken6494
    @jaken6494 Год назад

    love u too dad

  • @sepidehmortezaee4499
    @sepidehmortezaee4499 4 года назад

    🙏🏻🙏🏻🙏🏻🙏🏻🙏🏻

  • @dr-adamsheikhsaid3254
    @dr-adamsheikhsaid3254 9 месяцев назад

    LOVE YOU MAN

  • @DocLiabrary2k17
    @DocLiabrary2k17 Год назад

    ❤🎉

  • @mariamelsafty
    @mariamelsafty Год назад +1

    love u too

    • @HTBFopi
      @HTBFopi Год назад

      what about me?

  • @nehemiahwilson6864
    @nehemiahwilson6864 3 года назад

    Hilarious ending!

  • @sdiofjsoidjf
    @sdiofjsoidjf 3 года назад

    LIFESAVERS should be branded based on you

  • @radhasdfghjkl
    @radhasdfghjkl 2 года назад

    I love you too ❤

  • @nathaliegonzaleztorres1893
    @nathaliegonzaleztorres1893 3 года назад

    Love you too, Dirty 🥺

  • @fereshtahkhoshbakht1999
    @fereshtahkhoshbakht1999 4 года назад

    Omg I just think about this topic few hours ago😳😳

  • @xoxoserend1p1ty
    @xoxoserend1p1ty 4 года назад

    YAY!

  • @ghubb
    @ghubb Год назад

    fire

  • @ahmadsadain203
    @ahmadsadain203 4 года назад

    love

  • @drap9904
    @drap9904 4 года назад

    😃😃😃😃

  • @drkrunalpatelortho
    @drkrunalpatelortho 4 года назад

    D for dirty d for dubin d for Dark liver